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Volumn 50, Issue 8, 2015, Pages 1025-1031

Everolimus treatment for patients with autoimmune hepatitis and poor response to standard therapy and drug alternatives in use

Author keywords

Alternative treatment; Autoimmune hepatitis; Everolimus; Mammalian target of rapamycin inhibitor; Nonresponse; Poor response; Treatment

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTINUCLEAR ANTIBODY; AZATHIOPRINE; BUDESONIDE; CHOLESTEROL; CYCLOSPORIN; EVEROLIMUS; MYCOPHENOLATE MOFETIL; PREDNISOLONE; TACROLIMUS; CORTICOSTEROID; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID;

EID: 84929894634     PISSN: 00365521     EISSN: 15027708     Source Type: Journal    
DOI: 10.3109/00365521.2014.998271     Document Type: Article
Times cited : (40)

References (50)
  • 1
    • 0018866458 scopus 로고
    • Late results of the Royal Free Hospital prospective controlled trial of prednisolone therapy in hepatitis B surface antigen negative chronic active hepatitis
    • Kirk AP, Jain S, Pocock S, Thomas HC, Sherlock S. Late results of the Royal Free Hospital prospective controlled trial of prednisolone therapy in hepatitis B surface antigen negative chronic active hepatitis. Gut 1980;21:78-83.
    • (1980) Gut , vol.21 , pp. 78-83
    • Kirk, A.P.1    Jain, S.2    Pocock, S.3    Thomas, H.C.4    Sherlock, S.5
  • 2
  • 3
    • 33748897869 scopus 로고    scopus 로고
    • Persistent elevation of serum alanine aminotransferase levels leads to poor survival and hepatocellular carcinoma development in type 1 autoimmune hepatitis
    • Miyake Y, Iwasaki Y, Terada R, Okamaoto R, Ikeda H, Makino Y, et al. Persistent elevation of serum alanine aminotransferase levels leads to poor survival and hepatocellular carcinoma development in type 1 autoimmune hepatitis. Aliment Pharmacol Ther 2006;24:1197-205.
    • (2006) Aliment Pharmacol Ther , vol.24 , pp. 1197-1205
    • Miyake, Y.1    Iwasaki, Y.2    Terada, R.3    Okamaoto, R.4    Ikeda, H.5    Makino, Y.6
  • 4
    • 22844442418 scopus 로고    scopus 로고
    • Early treatment response predicts the need for liver transplantation in autoimmune hepatitis
    • Tan P, Marotta P, Ghent C, Adams P. Early treatment response predicts the need for liver transplantation in autoimmune hepatitis. Liver Int 2005;25:728-33.
    • (2005) Liver Int , vol.25 , pp. 728-733
    • Tan, P.1    Marotta, P.2    Ghent, C.3    Adams, P.4
  • 5
    • 0027293230 scopus 로고
    • Acute liver failure: Redefining the syndromes
    • O'Grady JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet 1993;342:273-5.
    • (1993) Lancet , vol.342 , pp. 273-275
    • O'Grady, J.G.1    Schalm, S.W.2    Williams, R.3
  • 7
    • 33645703754 scopus 로고    scopus 로고
    • Clinical characteristics of fulminant-type autoimmune hepatitis: An analysis of eleven cases
    • Miyake Y, Iwasaki Y, Terada R, Onishi T, Okamoto R, Sakai N, et al. Clinical characteristics of fulminant-type autoimmune hepatitis: an analysis of eleven cases. Aliment Pharmacol Ther 2006;23:1347-53.
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 1347-1353
    • Miyake, Y.1    Iwasaki, Y.2    Terada, R.3    Onishi, T.4    Okamoto, R.5    Sakai, N.6
  • 8
    • 34547394251 scopus 로고    scopus 로고
    • Usefulness of corticosteroids for the treatment of severe and fulminant forms of autoimmune hepatitis
    • Ichai P, Duclos-Vallee JC, Guettier C, Hamida SB, Antonini T, Delvart V, et al. Usefulness of corticosteroids for the treatment of severe and fulminant forms of autoimmune hepatitis. Liver Transpl 2007;13:996-1003.
    • (2007) Liver Transpl , vol.13 , pp. 996-1003
    • Ichai, P.1    Duclos-Vallee, J.C.2    Guettier, C.3    Hamida, S.B.4    Antonini, T.5    Delvart, V.6
  • 9
    • 37749002935 scopus 로고    scopus 로고
    • The impact of ethnicity on the natural history of autoimmune hepatitis
    • Verma S, Torbenson M, Thuluvath PJ. The impact of ethnicity on the natural history of autoimmune hepatitis. Hepatology 2007;46:1828-35.
    • (2007) Hepatology , vol.46 , pp. 1828-1835
    • Verma, S.1    Torbenson, M.2    Thuluvath, P.J.3
  • 10
    • 59649086033 scopus 로고    scopus 로고
    • Features and consequences of untreated type 1 autoimmune hepatitis
    • Czaja AJ. Features and consequences of untreated type 1 autoimmune hepatitis. Liver Int 2009;29:816-23.
    • (2009) Liver Int , vol.29 , pp. 816-823
    • Czaja, A.J.1
  • 11
    • 0035002235 scopus 로고    scopus 로고
    • Longterm management and prognosis of autoimmune hepatitis (AIH): A single center experience
    • Kanzler S, Lohr H, Gerken G, Galle PR, Lohse AW. Longterm management and prognosis of autoimmune hepatitis (AIH): a single center experience. Z Gastroenterol 2001;39: 339-8.
    • (2001) Z Gastroenterol , vol.39 , pp. 339-348
    • Kanzler, S.1    Lohr, H.2    Gerken, G.3    Galle, P.R.4    Lohse, A.W.5
  • 12
    • 0018866458 scopus 로고
    • Late results of the Royal Free Hospital prospective controlled trial of prednisolone therapy in hepatitis B surface antigen negative chronic active hepatitis
    • Kirk AP, Jain S, Pocock S, Thomas HC, Sherlock S. Late results of the Royal Free Hospital prospective controlled trial of prednisolone therapy in hepatitis B surface antigen negative chronic active hepatitis. Gut 1980;21:78-83.
    • (1980) Gut , vol.21 , pp. 78-83
    • Kirk, A.P.1    Jain, S.2    Pocock, S.3    Thomas, H.C.4    Sherlock, S.5
  • 13
    • 0015432456 scopus 로고
    • Clinical, biochemical, and histological remission of severe chronic active liver disease: A controlled study of treatments and early prognosis
    • Soloway RD, Summerskill WH, Baggenstoss AH, Geall MG, Gitnick GL, Elveback IR, et al. Clinical, biochemical, and histological remission of severe chronic active liver disease: a controlled study of treatments and early prognosis. Gastroenterology 1972;63:820-33.
    • (1972) Gastroenterology , vol.63 , pp. 820-833
    • Soloway, R.D.1    Summerskill, W.H.2    Baggenstoss, A.H.3    Geall, M.G.4    Gitnick, G.L.5    Elveback, I.R.6
  • 14
    • 0016802724 scopus 로고
    • Prednisone for chronic active liver disease: Dose titration, standard dose, and combination with azathioprine compared
    • Summerskill WH, Korman MG, Ammon HV, Baggenstoss AH. Prednisone for chronic active liver disease: dose titration, standard dose, and combination with azathioprine compared. Gut 1975;16:876-83.
    • (1975) Gut , vol.16 , pp. 876-883
    • Summerskill, W.H.1    Korman, M.G.2    Ammon, H.V.3    Baggenstoss, A.H.4
  • 15
    • 0015432456 scopus 로고
    • Clinical, biochemical, and histological remission of severe chronic active liver disease: A controlled study of treatments and early prognosis
    • Soloway RD, Summerskill WH, Baggenstoss AH, Geall MG, Gitnick GL, Elveback IR, et al. Clinical, biochemical, and histological remission of severe chronic active liver disease: a controlled study of treatments and early prognosis. Gastroenterology 1972;63:820-33.
    • (1972) Gastroenterology , vol.63 , pp. 820-833
    • Soloway, R.D.1    Summerskill, W.H.2    Baggenstoss, A.H.3    Geall, M.G.4    Gitnick, G.L.5    Elveback, I.R.6
  • 16
    • 77957345684 scopus 로고    scopus 로고
    • Budesonide induces remission more effectively than prednisone in a controlled trial of patients with autoimmune hepatitis
    • Manns MP, Woynarowski M, Kreisel W, Lurie Y, Rust C, Zuckerman E, et al. Budesonide induces remission more effectively than prednisone in a controlled trial of patients with autoimmune hepatitis. Gastroenterology 2010;139: 1198-206.
    • (2010) Gastroenterology , vol.139 , pp. 1198-1206
    • Manns, M.P.1    Woynarowski, M.2    Kreisel, W.3    Lurie, Y.4    Rust, C.5    Zuckerman, E.6
  • 19
    • 22844442303 scopus 로고    scopus 로고
    • Transplant immunosuppressive agents in non-transplant chronic autoimmune hepatitis: The Canadian association for the study of liver (CASL) experience with mycophenolate mofetil and tacrolimus
    • Chatur N, Ramji A, Bain VG, Ma MM, Marotta PJ, Ghent CN, et al. Transplant immunosuppressive agents in non-transplant chronic autoimmune hepatitis: the Canadian association for the study of liver (CASL) experience with mycophenolate mofetil and tacrolimus. Liver Int 2005;25: 723-7.
    • (2005) Liver Int , vol.25 , pp. 723-727
    • Chatur, N.1    Ramji, A.2    Bain, V.G.3    Ma, M.M.4    Marotta, P.J.5    Ghent, C.N.6
  • 20
    • 0023205295 scopus 로고
    • Cyclosporine treatment of autoimmune chronic active hepatitis
    • Hyams JS, Ballow M, Leichtner AM. Cyclosporine treatment of autoimmune chronic active hepatitis. Gastroenterology 1987;93:890-3.
    • (1987) Gastroenterology , vol.93 , pp. 890-893
    • Hyams, J.S.1    Ballow, M.2    Leichtner, A.M.3
  • 21
    • 34447521577 scopus 로고    scopus 로고
    • Low-dose tacrolimus ameliorates liver inflammation and fibrosis in steroid refractory autoimmune hepatitis
    • Larsen FS, Vainer B, Eefsen M, Bjerring PN, Adel HB. Low-dose tacrolimus ameliorates liver inflammation and fibrosis in steroid refractory autoimmune hepatitis. World J Gastroenterol 2007;13:3232-6.
    • (2007) World J Gastroenterol , vol.13 , pp. 3232-3236
    • Larsen, F.S.1    Vainer, B.2    Eefsen, M.3    Bjerring, P.N.4    Adel, H.B.5
  • 22
    • 0033845138 scopus 로고    scopus 로고
    • Mycophenolate mofetil for maintenance of remission in autoimmune hepatitis in patients resistant to or intolerant of azathioprine
    • Richardson PD, James PD, Ryder SD. Mycophenolate mofetil for maintenance of remission in autoimmune hepatitis in patients resistant to or intolerant of azathioprine. J Hepatol 2000;33:371-5.
    • (2000) J Hepatol , vol.33 , pp. 371-375
    • Richardson, P.D.1    James, P.D.2    Ryder, S.D.3
  • 23
    • 84860389502 scopus 로고    scopus 로고
    • Mycophenolate for the treatment of autoimmune hepatitis: Prospective assessment of its efficacy and safety for induction and maintenance of remission in a large cohort of treatment-naive patients
    • Zachou K, Gatselis N, Papadamou G, Rigopoulou EI, Dalekos GN. Mycophenolate for the treatment of autoimmune hepatitis: prospective assessment of its efficacy and safety for induction and maintenance of remission in a large cohort of treatment-naive patients. J Hepatol 2011;55: 636-46.
    • (2011) J Hepatol , vol.55 , pp. 636-646
    • Zachou, K.1    Gatselis, N.2    Papadamou, G.3    Rigopoulou, E.I.4    Dalekos, G.N.5
  • 25
    • 34447521577 scopus 로고    scopus 로고
    • Low-dose tacrolimus ameliorates liver inflammation and fibrosis in steroid refractory autoimmune hepatitis
    • Larsen FS, Vainer B, Eefsen M, Bjerring PN, Adel HB. Low-dose tacrolimus ameliorates liver inflammation and fibrosis in steroid refractory autoimmune hepatitis. World J Gastroenterol 2007;13:3232-6.
    • (2007) World J Gastroenterol , vol.13 , pp. 3232-3236
    • Larsen, F.S.1    Vainer, B.2    Eefsen, M.3    Bjerring, P.N.4    Adel, H.B.5
  • 26
    • 77958508170 scopus 로고    scopus 로고
    • Mycophenolate mofetil for the treatment of autoimmune hepatitis in patients refractory or intolerant to conventional therapy
    • Sharzehi K, Huang MA, Schreibman IR, Brown KA. Mycophenolate mofetil for the treatment of autoimmune hepatitis in patients refractory or intolerant to conventional therapy. Can J Gastroenterol 2010;24:588-92.
    • (2010) Can J Gastroenterol , vol.24 , pp. 588-592
    • Sharzehi, K.1    Huang, M.A.2    Schreibman, I.R.3    Brown, K.A.4
  • 28
    • 84860389502 scopus 로고    scopus 로고
    • Mycophenolate for the treatment of autoimmune hepatitis: Prospective assessment of its efficacy and safety for induction and maintenance of remission in a large cohort of treatment-naive patients
    • Zachou K, Gatselis N, Papadamou G, Rigopoulou EI, Dalekos GN. Mycophenolate for the treatment of autoimmune hepatitis: prospective assessment of its efficacy and safety for induction and maintenance of remission in a large cohort of treatment-naive patients. J Hepatol 2011;55:636-46.
    • (2011) J Hepatol , vol.55 , pp. 636-646
    • Zachou, K.1    Gatselis, N.2    Papadamou, G.3    Rigopoulou, E.I.4    Dalekos, G.N.5
  • 30
    • 34447096274 scopus 로고    scopus 로고
    • Mycophenolate mofetil in autoimmune hepatitis patients not responsive or intolerant to standard immunosuppressive therapy
    • Inductivo-Yu I, Adams A, Gish RG, Wakil A, Bzowej NH, Frederick RT, et al. Mycophenolate mofetil in autoimmune hepatitis patients not responsive or intolerant to standard immunosuppressive therapy. Clin Gastroenterol Hepatol 2007;5:799-802.
    • (2007) Clin Gastroenterol Hepatol , vol.5 , pp. 799-802
    • Inductivo-Yu, I.1    Adams, A.2    Gish, R.G.3    Wakil, A.4    Bzowej, N.H.5    Frederick, R.T.6
  • 32
    • 0032718310 scopus 로고    scopus 로고
    • International Autoimmune Hepatitis Group Report: Review of criteria for diagnosis of autoimmune hepatitis
    • Alvarez F, Berg PA, Bianchi FB, Bianchi L, Burroughs AK, Cancado EL, et al. International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999;31:929-38.
    • (1999) J Hepatol , vol.31 , pp. 929-938
    • Alvarez, F.1    Berg, P.A.2    Bianchi, F.B.3    Bianchi, L.4    Burroughs, A.K.5    Cancado, E.L.6
  • 33
    • 0035002235 scopus 로고    scopus 로고
    • Longterm management and prognosis of autoimmune hepatitis (AIH): A single center experience
    • Kanzler S, Lohr H, Gerken G, Galle PR, Lohse AW. Longterm management and prognosis of autoimmune hepatitis (AIH): a single center experience. Z Gastroenterol 2001;39: 339-8.
    • (2001) Z Gastroenterol , vol.39 , pp. 339-348
    • Kanzler, S.1    Lohr, H.2    Gerken, G.3    Galle, P.R.4    Lohse, A.W.5
  • 34
    • 0018866458 scopus 로고
    • Late results of the Royal Free Hospital prospective controlled trial of prednisolone therapy in hepatitis B surface antigen negative chronic active hepatitis
    • Kirk AP, Jain S, Pocock S, Thomas HC, Sherlock S. Late results of the Royal Free Hospital prospective controlled trial of prednisolone therapy in hepatitis B surface antigen negative chronic active hepatitis. Gut 1980;21:78-83.
    • (1980) Gut , vol.21 , pp. 78-83
    • Kirk, A.P.1    Jain, S.2    Pocock, S.3    Thomas, H.C.4    Sherlock, S.5
  • 35
    • 34047223229 scopus 로고    scopus 로고
    • Consequences of treatment withdrawal in type 1 autoimmune hepatitis
    • Montano-Loza AJ, Carpenter HA, Czaja AJ. Consequences of treatment withdrawal in type 1 autoimmune hepatitis. Liver Int 2007;27:507-15.
    • (2007) Liver Int , vol.27 , pp. 507-515
    • Montano-Loza, A.J.1    Carpenter, H.A.2    Czaja, A.J.3
  • 36
    • 0015432456 scopus 로고
    • Clinical, biochemical, and histological remission of severe chronic active liver disease: A controlled study of treatments and early prognosis
    • Soloway RD, Summerskill WH, Baggenstoss AH, Geall MG, Gitnick GL, Elveback IR, et al. Clinical, biochemical, and histological remission of severe chronic active liver disease: a controlled study of treatments and early prognosis. Gastroenterology 1972;63:820-33.
    • (1972) Gastroenterology , vol.63 , pp. 820-833
    • Soloway, R.D.1    Summerskill, W.H.2    Baggenstoss, A.H.3    Geall, M.G.4    Gitnick, G.L.5    Elveback, I.R.6
  • 37
    • 0032403227 scopus 로고    scopus 로고
    • Successful treatment of refractory type 1 autoimmune hepatitis with methotrexate
    • Burak KW, Urbanski SJ, Swain MG. Successful treatment of refractory type 1 autoimmune hepatitis with methotrexate. J Hepatol 1998;29:990-3.
    • (1998) J Hepatol , vol.29 , pp. 990-993
    • Burak, K.W.1    Urbanski, S.J.2    Swain, M.G.3
  • 38
    • 8544229063 scopus 로고    scopus 로고
    • Cyclophosphamide as alternative immunosuppressive therapy for autoimmune hepatitis-report of three cases
    • Kanzler S, Gerken G, Dienes HP, Meyer zum Buschenfelde KH, Lohse AW. Cyclophosphamide as alternative immunosuppressive therapy for autoimmune hepatitis-report of three cases. Z Gastroenterol 1997;35:571-8.
    • (1997) Z Gastroenterol , vol.35 , pp. 571-578
    • Kanzler, S.1    Gerken, G.2    Dienes, H.P.3    Meyerzum Buschenfelde, K.H.4    Lohse, A.W.5
  • 41
    • 80051696782 scopus 로고    scopus 로고
    • Tolerability of everolimus-based immunosuppression in maintenance liver transplant recipients
    • Vallin M, Guillaud O, Morard I, Gagnieu MC, Mentha G, Adham M, et al. Tolerability of everolimus-based immunosuppression in maintenance liver transplant recipients. Clin Transplant 2011;25:660-9.
    • (2011) Clin Transplant , vol.25 , pp. 660-669
    • Vallin, M.1    Guillaud, O.2    Morard, I.3    Gagnieu, M.C.4    Mentha, G.5    Adham, M.6
  • 42
    • 5444267283 scopus 로고    scopus 로고
    • Tolerability and steady-state pharmacokinetics of everolimus in maintenance renal transplant patients
    • Budde K, Neumayer HH, Lehne G, Winkler M, Hauser IA, Lison A, et al. Tolerability and steady-state pharmacokinetics of everolimus in maintenance renal transplant patients. Nephrol Dial Transplant 2004;19:2606-14.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 2606-2614
    • Budde, K.1    Neumayer, H.H.2    Lehne, G.3    Winkler, M.4    Hauser, I.A.5    Lison, A.6
  • 43
    • 77953407754 scopus 로고    scopus 로고
    • Everolimus- A new approach in the treatment of renal cell carcinoma
    • Anandappa G, Hollingdale A, Eisen T. Everolimus- A new approach in the treatment of renal cell carcinoma. Cancer Manag Res 2010;2:61-70.
    • (2010) Cancer Manag Res , vol.2 , pp. 61-70
    • Anandappa, G.1    Hollingdale, A.2    Eisen, T.3
  • 44
    • 84859711356 scopus 로고    scopus 로고
    • Everolimus plus early tacrolimus minimization: A phase III, randomized, openlabel, multicentre trial in renal transplantation
    • Langer RM, Hene R, Vitko S, Christiaans M, Tedesco-Silva H Jr, Ciechanowski K, et al. Everolimus plus early tacrolimus minimization: a phase III, randomized, openlabel, multicentre trial in renal transplantation. Transpl Int 2012;25:592-602.
    • (2012) Transpl Int , vol.25 , pp. 592-602
    • Langer, R.M.1    Hene, R.2    Vitko, S.3    Christiaans, M.4    Tedesco-Silva, H.5    Ciechanowski, K.6
  • 45
    • 48649107474 scopus 로고    scopus 로고
    • Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebocontrolled phase III trial
    • Motzer RJ, Escudier B, Oudard S, Hutson TE, Porta C, Bracarda S, et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebocontrolled phase III trial. Lancet 2008;372:449-56.
    • (2008) Lancet , vol.372 , pp. 449-456
    • Motzer, R.J.1    Escudier, B.2    Oudard, S.3    Hutson, T.E.4    Porta, C.5    Bracarda, S.6
  • 46
    • 84859711356 scopus 로고    scopus 로고
    • Everolimus plus early tacrolimus minimization: A phase III, randomized, openlabel, multicentre trial in renal transplantation
    • Langer RM, Hene R, Vitko S, Christiaans M, Tedesco-Silva H Jr, Ciechanowski K, et al. Everolimus plus early tacrolimus minimization: a phase III, randomized, openlabel, multicentre trial in renal transplantation. Transpl Int 2012;25:592-602.
    • (2012) Transpl Int , vol.25 , pp. 592-602
    • Langer, R.M.1    Hene, R.2    Vitko, S.3    Christiaans, M.4    Tedesco-Silva, H.5    Ciechanowski, K.6
  • 47
    • 48649107474 scopus 로고    scopus 로고
    • Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebocontrolled phase III trial
    • Motzer RJ, Escudier B, Oudard S, Hutson TE, Porta C, Bracarda S, et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebocontrolled phase III trial. Lancet 2008;372:449-56.
    • (2008) Lancet , vol.372 , pp. 449-456
    • Motzer, R.J.1    Escudier, B.2    Oudard, S.3    Hutson, T.E.4    Porta, C.5    Bracarda, S.6
  • 49
    • 81355138582 scopus 로고    scopus 로고
    • MTOR inhibitors: What role in liver transplantation?
    • Kawahara T, Asthana S, Kneteman NM. m-TOR inhibitors: what role in liver transplantation? JHepatol 2011;55:1441-51.
    • (2011) J Hepatol , vol.55 , pp. 1441-1451
    • Kawahara, T.1    Asthana, S.2    Kneteman, N.M.3


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