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Volumn 1, Issue 1, 2012, Pages 107-118

Genetic deficiency of complement component 3 does not alter disease progression in a mouse model of Huntington's disease

Author keywords

Complement C3; Huntington disease; immunity; innate; neurodegenerative diseases

Indexed keywords

COMPLEMENT COMPONENT C3;

EID: 84929877921     PISSN: 18796397     EISSN: 18796400     Source Type: Journal    
DOI: 10.3233/JHD-2012-120021     Document Type: Article
Times cited : (23)

References (47)
  • 1
    • 45149107487 scopus 로고    scopus 로고
    • Mechanisms of neurodegeneration in Huntington's disease
    • Gil JM, Rego AC. Mechanisms of neurodegeneration in Huntington's disease. Eur J Neurosci. 2008;27(11):2803-20.
    • (2008) Eur J Neurosci , vol.27 , Issue.11 , pp. 2803-2820
    • Gil, J.M.1    Rego, A.C.2
  • 7
    • 78651422988 scopus 로고    scopus 로고
    • Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: A multimodal imaging study
    • Politis M, Pavese N, Tai YF, Kiferle L, Mason SL, Brooks DJ, Tabrizi SJ, Barker RA, Piccini P. Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: A multimodal imaging study. Hum Brain Mapp. 2011;32(2):258-70.
    • (2011) Hum Brain Mapp , vol.32 , Issue.2 , pp. 258-270
    • Politis, M.1    Pavese, N.2    Tai, Y.F.3    Kiferle, L.4    Mason, S.L.5    Brooks, D.J.6    Tabrizi, S.J.7    Barker, R.A.8    Piccini, P.9
  • 9
    • 0032873347 scopus 로고    scopus 로고
    • Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease
    • Singhrao SK, Neal JW, Morgan BP, Gasque P. Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease. Exp Neurol. 1999;362-76.
    • (1999) Exp Neurol , pp. 362-376
    • Singhrao, S.K.1    Neal, J.W.2    Morgan, B.P.3    Gasque, P.4
  • 11
    • 0029558338 scopus 로고
    • Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity
    • Wessels MR, Butko P, Ma M, Warren HB, Lage AL, Carroll MC. Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity. Proc Natl Acad Sci USA. 1995;92(25):11490-4.
    • (1995) Proc Natl Acad Sci USA. , vol.92 , Issue.25 , pp. 11490-11494
    • Wessels, M.R.1    Butko, P.2    Ma, M.3    Warren, H.B.4    Lage, A.L.5    Carroll, M.C.6
  • 15
    • 84856007233 scopus 로고    scopus 로고
    • Sialic acid on the neuronal glycocalyx prevents complement C1 binding and complement receptor-3-mediated removal by microglia
    • Linnartz B, Kopatz J, Tenner AJ, Neumann H. Sialic acid on the neuronal glycocalyx prevents complement C1 binding and complement receptor-3-mediated removal by microglia. J Neurosci. 2012;32(3):946-52.
    • (2012) J Neurosci. , vol.32 , Issue.3 , pp. 946-952
    • Linnartz, B.1    Kopatz, J.2    Tenner, A.J.3    Neumann, H.4
  • 17
    • 4644328027 scopus 로고    scopus 로고
    • Deletion of the complement anaphylatoxin C3a receptor attenuates, whereas ectopic expression of C3a in the brain exacerbates, experimental autoimmune encephalomyelitis
    • Boos L, Campbell IL, Ames R, Wetsel RA, Barnum SR. Deletion of the complement anaphylatoxin C3a receptor attenuates, whereas ectopic expression of C3a in the brain exacerbates, experimental autoimmune encephalomyelitis. J Immunol. 2004;173(7):4708-14.
    • (2004) J Immunol. , vol.173 , Issue.7 , pp. 4708-4714
    • Boos, L.1    Campbell, I.L.2    Ames, R.3    Wetsel, R.A.4    Barnum, S.R.5
  • 18
    • 0033214747 scopus 로고    scopus 로고
    • Glial responses to synaptic damage and plasticity
    • Aldskogius H, Liu L, Svensson M. Glial responses to synaptic damage and plasticity. J Neurosci Res. 1999;58(1):33-41.
    • (1999) J Neurosci Res , vol.58 , Issue.1 , pp. 33-41
    • Aldskogius, H.1    Liu, L.2    Svensson, M.3
  • 20
    • 46749087854 scopus 로고    scopus 로고
    • Complement C3 deficiency leads to accelerated amyloid {beta} plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice
    • Maier M, Peng Y, Jiang L, Seabrook TJ, Carroll MC, Lemere CA. Complement C3 deficiency leads to accelerated amyloid {beta} plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice. J Neurosci. 2008;28(25):6333-41.
    • (2008) J Neurosci , vol.28 , Issue.25 , pp. 6333-6341
    • Maier, M.1    Peng, Y.2    Jiang, L.3    Seabrook, T.J.4    Carroll, M.C.5    Lemere, C.A.6
  • 21
    • 48749128086 scopus 로고    scopus 로고
    • Disruption of the complement cascade delays retinal ganglion cell death following retinal ischemia-reperfusion
    • Kuehn MH, Kim CY, Jiang B, Dumitrescu AV, Kwon YH. Disruption of the complement cascade delays retinal ganglion cell death following retinal ischemia-reperfusion. Exp Eye Res. 2008;87(2):89-95.
    • (2008) Exp Eye Res , vol.87 , Issue.2 , pp. 89-95
    • Kuehn, M.H.1    Kim, C.Y.2    Jiang, B.3    Dumitrescu, A.V.4    Kwon, Y.H.5
  • 23
    • 80052074316 scopus 로고    scopus 로고
    • The role of immunity in Huntington's disease
    • Soulet D, Cicchetti F. The role of immunity in Huntington's disease. Mol Psychiatry. 2011;16(9):889-902.
    • (2011) Mol Psychiatry , vol.16 , Issue.9 , pp. 889-902
    • Soulet, D.1    Cicchetti, F.2
  • 24
    • 36048937343 scopus 로고    scopus 로고
    • Complement-targeted therapeutics
    • Ricklin D, Lambris JD. Complement-targeted therapeutics. Nat Biotechnol. 2007;25(11):1265-75.
    • (2007) Nat Biotechnol , vol.25 , Issue.11 , pp. 1265-1275
    • Ricklin, D.1    Lambris, J.D.2
  • 25
    • 70450224874 scopus 로고    scopus 로고
    • Recent developments in low molecular weight complement inhibitors
    • Qu H, Ricklin D, Lambris JD. Recent developments in low molecular weight complement inhibitors. Mol Immunol. 2009;47(2-3):185-95.
    • (2009) Mol Immunol , vol.47 , Issue.2-3 , pp. 185-195
    • Qu, H.1    Ricklin, D.2    Lambris, J.D.3
  • 26
    • 0035214922 scopus 로고    scopus 로고
    • Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice
    • Klapstein GJ, Fisher RS, Zanjani H, Cepeda C, Jokel ES, Chesselet MF, Levine MS. Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice. J Neurophysiol. 2001;86(6):2667-77.
    • (2001) J Neurophysiol , vol.86 , Issue.6 , pp. 2667-2677
    • Klapstein, G.J.1    Fisher, R.S.2    Zanjani, H.3    Cepeda, C.4    Jokel, E.S.5    Chesselet, M.F.6    Levine, M.S.7
  • 28
    • 80055122189 scopus 로고    scopus 로고
    • Microdissection of rat brain for RNA or protein extraction from specific brain region
    • Chiu K, Lau WM, Lau HT, So K-F, Chang RC-C. Microdissection of rat brain for RNA or protein extraction from specific brain region. J Vis Exp. 2007;(7):269.
    • (2007) J Vis Exp , Issue.7 , pp. 269
    • Chiu, K.1    Lau, W.M.2    Lau, H.T.3    So, K.-F.4    Chang, R.C.-C.5
  • 29
    • 56549119132 scopus 로고    scopus 로고
    • Optimisation of region-specific reference gene selection and relative gene expression analysis methods for pre-clinical trials of Huntington's disease
    • Benn CL, Fox H, Bates GP. Optimisation of region-specific reference gene selection and relative gene expression analysis methods for pre-clinical trials of Huntington's disease. Mol Neurodegener. 2008;3:17.
    • (2008) Mol Neurodegener , vol.3 , pp. 17
    • Benn, C.L.1    Fox, H.2    Bates, G.P.3
  • 36
    • 66749119970 scopus 로고    scopus 로고
    • Genetic knock-down of HDAC7 does not ameliorate disease pathogenesis in the R6/2 mouse model of Huntington's disease
    • Benn CL, Butler R, Mariner L, Nixon J, Moffitt H, Mielcarek M, Woodman B, Bates GP. Genetic knock-down of HDAC7 does not ameliorate disease pathogenesis in the R6/2 mouse model of Huntington's disease. PLoS ONE. 2009;4(6):e5747.
    • (2009) PLoS ONE , vol.4 , Issue.6 , pp. e5747
    • Benn, C.L.1    Butler, R.2    Mariner, L.3    Nixon, J.4    Moffitt, H.5    Mielcarek, M.6    Woodman, B.7    Bates, G.P.8
  • 39
    • 68249112361 scopus 로고    scopus 로고
    • Distinct neuroinflammatory profile in post-mortem human Huntington's disease
    • Silvestroni A, Faull RLM, Strand AD, Moller T. Distinct neuroinflammatory profile in post-mortem human Huntington's disease. Neuroreport. 2009;20(12):1098-103.
    • (2009) Neuroreport , vol.20 , Issue.12 , pp. 1098-1103
    • Silvestroni, A.1    Faull, R.L.M.2    Strand, A.D.3    Moller, T.4
  • 42
    • 79952579942 scopus 로고    scopus 로고
    • Neurodegenerative disease and adult neurogenesis
    • Winner B, Kohl Z, Gage FH. Neurodegenerative disease and adult neurogenesis. Eur J Neurosci. 2011;33(6):1139-51.
    • (2011) Eur J Neurosci , vol.33 , Issue.6 , pp. 1139-1151
    • Winner, B.1    Kohl, Z.2    Gage, F.H.3
  • 43
    • 23644456320 scopus 로고    scopus 로고
    • C3a expressed in the central nervous system protects against LPS-induced shock
    • Boos L, Szalai AJ, Barnum SR. C3a expressed in the central nervous system protects against LPS-induced shock. Neurosci Lett. 2005;387(2):68-71.
    • (2005) Neurosci Lett , vol.387 , Issue.2 , pp. 68-71
    • Boos, L.1    Szalai, A.J.2    Barnum, S.R.3
  • 44
    • 0034670027 scopus 로고    scopus 로고
    • Cutting edge: Targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock
    • Kildsgaard J, Hollmann TJ, Matthews KW, Bian K, Murad F, Wetsel RA. Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock. J Immunol. 2000;165(10):5406-9.
    • (2000) J Immunol , vol.165 , Issue.10 , pp. 5406-5409
    • Kildsgaard, J.1    Hollmann, T.J.2    Matthews, K.W.3    Bian, K.4    Murad, F.5    Wetsel, R.A.6
  • 45
    • 62549118640 scopus 로고    scopus 로고
    • C3a receptor deficiency accelerates the onset of renal injury in the MRL/lpr mouse
    • Wenderfer SE, Wang H, Ke B, Wetsel RA, Braun MC. C3a receptor deficiency accelerates the onset of renal injury in the MRL/lpr mouse. Mol Immunol. 2009;46(7):1397-404.
    • (2009) Mol Immunol , vol.46 , Issue.7 , pp. 1397-1404
    • Wenderfer, S.E.1    Wang, H.2    Ke, B.3    Wetsel, R.A.4    Braun, M.C.5
  • 47
    • 34447336141 scopus 로고    scopus 로고
    • The complement system in liver diseases
    • Qin X, Gao B. The complement system in liver diseases. Cell Mol Immunol. 2006;3(5):333-40.
    • (2006) Cell Mol Immunol , vol.3 , Issue.5 , pp. 333-340
    • Qin, X.1    Gao, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.