-
1
-
-
84857225422
-
Argonaute and the Nuclear RNAs: New pathways for RNA-mediated control of gene expression
-
Gagnon KT and DR Corey (2012). Argonaute and the Nuclear RNAs: new pathways for RNA-mediated control of gene expression. Nucleic Acid Ther 22:3-16.
-
(2012)
Nucleic Acid Ther
, vol.22
, pp. 3-16
-
-
Gagnon, K.T.1
Corey, D.R.2
-
2
-
-
84891930123
-
Chromatin remodeling by small RNA machinery in mammalian cells
-
Li LC (2014). Chromatin remodeling by small RNA machinery in mammalian cells. Epigenetics 9:45-52.
-
(2014)
Epigenetics
, vol.9
, pp. 45-52
-
-
Li, L.C.1
-
3
-
-
84872533627
-
RNA Interference in the nucleus: Roles for small RNAs in transcription, epigenetics, and beyond
-
Castel SE and RA Martienssen (2013). RNA Interference in the nucleus: roles for small RNAs in transcription, epigenetics, and beyond. Nat Rev Genet 14:100-112.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 100-112
-
-
Castel, S.E.1
Martienssen, R.A.2
-
4
-
-
84906938579
-
Import routes and nuclear functions of argonaute and other small RNA-silencing proteins
-
Schraivogel D and G Meister (2014). Import routes and nuclear functions of argonaute and other small RNA-silencing proteins. Trends Biochem Sci 39:420-431.
-
(2014)
Trends Biochem Sci
, vol.39
, pp. 420-431
-
-
Schraivogel, D.1
Meister, G.2
-
5
-
-
84902011435
-
Human nuclear dicer restricts the deleterious accumulation of endogenous double-stranded RNA
-
White E, M Schacklow, K Kamieniarz-Gdula, NJ Proudfoot and M Gullerova (2014). Human nuclear dicer restricts the deleterious accumulation of endogenous double-stranded RNA. Nat Struc Mol Biol 21:552-559.
-
(2014)
Nat Struc Mol Biol
, vol.21
, pp. 552-559
-
-
White, E.1
Schacklow, M.2
Kamieniarz-Gdula, K.3
Proudfoot, N.J.4
Gullerova, M.5
-
6
-
-
84923572337
-
The varied roles of nuclear argonaute-small RNA complexes and avenues for therapy
-
Ross JP and Kassir Z (2014). The varied roles of nuclear argonaute-small RNA complexes and avenues for therapy. Mol Ther Nucl Acids 3:e203.
-
(2014)
Mol Ther Nucl Acids
, vol.3
, pp. e203
-
-
Ross, J.P.1
Kassir, Z.2
-
7
-
-
84890409577
-
A Network of noncoding RNAs links transcription of inflammatory pathway genes COX-2 and PLAG24A
-
Matsui M, H Zhang, Y Chu, KT Gagnon, M Manoharan, DR Corey and BA Janowski (2013). A Network of noncoding RNAs links transcription of inflammatory pathway genes COX-2 and PLAG24A. Nucleic Acids Res 41:10086-10109.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 10086-10109
-
-
Matsui, M.1
Zhang, H.2
Chu, Y.3
Gagnon, K.T.4
Manoharan, M.5
Corey, D.R.6
Janowski, B.A.7
-
8
-
-
84873626217
-
Long non-coding RNA targeting and transcriptional de-repression
-
Weinberg MS and KV Morris (2013). Long non-coding RNA targeting and transcriptional de-repression. Nucleic Acid Ther 23:9-4.
-
(2013)
Nucleic Acid Ther
, vol.23
, pp. 9-14
-
-
Weinberg, M.S.1
Morris, K.V.2
-
9
-
-
40349094597
-
MicroRNA-373 induces expression of genes with complementary promoter sequences
-
Place RF, LC Li, D Pookot, EJ Noonan and R Dahiya (2001). MicroRNA-373 induces expression of genes with complementary promoter sequences. Proc Natl Acad Sci (USA) 105:1608-613.
-
(2001)
Proc Natl Acad Sci (USA)
, vol.105
, pp. 1608-1613
-
-
Place, R.F.1
Li, L.C.2
Pookot, D.3
Noonan, E.J.4
Dahiya, R.5
-
10
-
-
55849135596
-
MicroRNA-directed transcriptional gene silencing in mammalian cells
-
Kim DH, P Saetrom, O Snove and JJ Rossi (2008). MicroRNA-directed transcriptional gene silencing in mammalian cells. Proc Natl Acad Sci 105:16230-16235.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 16230-16235
-
-
Kim, D.H.1
Saetrom, P.2
Snove, O.3
Rossi, J.J.4
-
11
-
-
79959347056
-
Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters
-
Younger ST and DR Corey (2011). Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters. Nucl Acids Res 39:5682-5691.
-
(2011)
Nucl Acids Res
, vol.39
, pp. 5682-5691
-
-
Younger, S.T.1
Corey, D.R.2
-
13
-
-
84855822424
-
Intracellular localization and routing of miRNA and RNAi pathway components
-
Orht T, J Muetze, P Svoboda and P Schwille, P (2012). Intracellular localization and routing of miRNA and RNAi pathway components. Curr Top Med Chem 12:79-8.
-
(2012)
Curr Top Med Chem
, vol.12
, pp. 79-88
-
-
Orht, T.1
Muetze, J.2
Svoboda, P.3
Schwille, P.4
-
14
-
-
84892544892
-
RNAi factors are present and active in mammalian cell nuclei
-
Gagnon KT, L Li, Y Chu, BA Janowski and DR Corey (2014). RNAi factors are present and active in mammalian cell nuclei. Cell Reports 6:211-221.
-
(2014)
Cell Reports
, vol.6
, pp. 211-221
-
-
Gagnon, K.T.1
Li, L.2
Chu, Y.3
Janowski, B.A.4
Corey, D.R.5
-
15
-
-
84901830311
-
Antisense-mediated exon skipping: Taking advantage of a trick from Mother Nature to treat rare genetic diseases
-
Veltrop M and A Aartsma-Rus (2014). Antisense-mediated exon skipping: taking advantage of a trick from Mother Nature to treat rare genetic diseases. Exper Cell Res 325:50-55.
-
(2014)
Exper Cell Res
, vol.325
, pp. 50-55
-
-
Veltrop, M.1
Aartsma-Rus, A.2
-
16
-
-
84893541929
-
A chemical view of oligonucleotides for exon skipping and related drug applications
-
Jarver P, L O'Donovan and MJ Gait (2014). A chemical view of oligonucleotides for exon skipping and related drug applications. Nucleic Acid Ther 24:37-47.
-
(2014)
Nucleic Acid Ther
, vol.24
, pp. 37-47
-
-
Jarver, P.1
O'Donovan, L.2
Gait, M.J.3
-
17
-
-
84921996531
-
Antisense oligonucleotide-based therapies for diseases caused by pre-mRNA processing defects
-
Rigo F, PP Seth and CF Bennett (2014). Antisense oligonucleotide-based therapies for diseases caused by pre-mRNA processing defects. Adv Exp Med Biol 825:303-352.
-
(2014)
Adv Exp Med Biol
, vol.825
, pp. 303-352
-
-
Rigo, F.1
Seth, P.P.2
Bennett, C.F.3
-
18
-
-
84916613367
-
The influence of argonaute proteins on alternative RNA splicing
-
Battsche E and M Ameyar-Zazoua (2014). The influence of argonaute proteins on alternative RNA splicing. Wiley Interdiscip Rev. RNA 6:141-156.
-
(2014)
Wiley Interdiscip Rev. RNA
, vol.6
, pp. 141-156
-
-
Battsche, E.1
Ameyar-Zazoua, M.2
-
19
-
-
84863116114
-
Expanding the action of duplex RNAs into the nucleus: Redirecting alternative splicing
-
Liu J, J Hu, and DR Corey (2012). Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicing. Nucl Acids Res 40:1240-1250.
-
(2012)
Nucl Acids Res
, vol.40
, pp. 1240-1250
-
-
Liu, J.1
Hu, J.2
Corey, D.R.3
-
20
-
-
67650299463
-
Control of alternative splicing through siRNA-mediated transcriptional gene silencing
-
Allo M, V Buggiano, JP Fededa, E Petrillo, I Schor, M de la Mata, E Agirre, M Plass, E Eyras, et al. (2009). Control of alternative splicing through siRNA-mediated transcriptional gene silencing. Nat Struc Mol Biol 16:717-724.
-
(2009)
Nat Struc Mol Biol
, vol.16
, pp. 717-724
-
-
Allo, M.1
Buggiano, V.2
Fededa, J.P.3
Petrillo, E.4
Schor, I.5
De La Mata, M.6
Agirre, E.7
Plass, M.8
Eyras, E.9
-
21
-
-
84929881784
-
Control of alternative splicing through siRNA-mediated transcriptional gene silencing
-
Ameyar-Zazoua M, C Rachez, M Souidi, P Robin, L Fritsch, R Young, N Morozova, R Fenouil, N Descostes, et al. (2014). Control of alternative splicing through siRNA-mediated transcriptional gene silencing. Nat Struc Mol Biol 19:998-1004.
-
(2014)
Nat Struc Mol Biol
, vol.19
, pp. 998-1004
-
-
Ameyar-Zazoua, M.1
Rachez, C.2
Souidi, M.3
Robin, P.4
Fritsch, L.5
Young, R.6
Morozova, N.7
Fenouil, R.8
Descostes, N.9
-
22
-
-
84914674878
-
Argonaute-1 binds transcriptional enhances and controls constitutive and alternative splicing in human cells
-
2104
-
Allo M, E Agirre, S Bessonov, P Bertucci, L Gomez Acuna, V Buggiano, N Bellora, B Singh, E Petrillo, et al. (2104). Argonaute-1 binds transcriptional enhances and controls constitutive and alternative splicing in human cells. Proc Natl Acad Sci (USA) 111:15622-15629.
-
Proc Natl Acad Sci (USA)
, vol.111
, pp. 15622-15629
-
-
Allo, M.1
Agirre, E.2
Bessonov, S.3
Bertucci, P.4
Gomez Acuna, L.5
Buggiano, V.6
Bellora, N.7
Singh, B.8
Petrillo, E.9
-
23
-
-
84865682650
-
Single-stranded siRNAs activate RNAi in animals
-
Lima WF, TP Prakash, HM Murray, GA Kinberger, W Li, AE Chappell, CS Li, SF Murray, H Gaus, et al. (2012). Single-stranded siRNAs activate RNAi in animals. Cell 150: 883-894.
-
(2012)
Cell
, vol.150
, pp. 883-894
-
-
Lima, W.F.1
Prakash, T.P.2
Murray, H.M.3
Kinberger, G.A.4
Li, W.5
Chappell, A.E.6
Li, C.S.7
Murray, S.F.8
Gaus, H.9
-
24
-
-
84880529654
-
Lipid nanoparticles improve activity of single-stranded siRNA and gapmer antisense oligonucleotides in animals
-
Prakash TP, WF Lima, HM Murray, S Elbashir, W Cantley, D Foster, M Jayaraman, AE Chappell, M Manoharan, EE Swayze and ST Crooke. (2013). Lipid nanoparticles improve activity of single-stranded siRNA and gapmer antisense oligonucleotides in animals. ACS Chem Biol 8:1402-1406.
-
(2013)
ACS Chem Biol
, vol.8
, pp. 1402-1406
-
-
Prakash, T.P.1
Lima, W.F.2
Murray, H.M.3
Elbashir, S.4
Cantley, W.5
Foster, D.6
Jayaraman, M.7
Chappell, A.E.8
Manoharan, M.9
Swayze, E.E.10
Crooke, S.T.11
-
25
-
-
84865688581
-
Single-stranded RNAs that function through RNAi are potent and allele-selective inhibitors of huntingtin expression
-
Yu D, H Pendergraff, J Liu, HB Kordasiewicz, DW Cleveland, E Swayze, W Lima, ST Crooke, T Prakash and DR Corey. (2012). Single-stranded RNAs that function through RNAi are potent and allele-selective inhibitors of huntingtin expression. Cell 150:895-908.
-
(2012)
Cell
, vol.150
, pp. 895-908
-
-
Yu, D.1
Pendergraff, H.2
Liu, J.3
Kordasiewicz, H.B.4
Cleveland, D.W.5
Swayze, E.6
Lima, W.7
Crooke, S.T.8
Prakash, T.9
Corey, D.R.10
-
26
-
-
84900842932
-
Exploring the effect of sequence length and composition on allele-selective inhibition of human huntingtin expression by single-stranded silencing RNAs
-
Hu J, J Lui, D Yu, Y Aiba, S Lee, H Pendergraff, J Boubaker, JW Arates, C Lagier-Tourenne, et al. (2014). Exploring the effect of sequence length and composition on allele-selective inhibition of human huntingtin expression by single-stranded silencing RNAs. Nucleic Acid Ther 24:199-209.
-
(2014)
Nucleic Acid Ther
, vol.24
, pp. 199-209
-
-
Hu, J.1
Lui, J.2
Yu, D.3
Aiba, Y.4
Lee, S.5
Pendergraff, H.6
Boubaker, J.7
Arates, J.W.8
Lagier-Tourenne, C.9
-
27
-
-
84890015655
-
ss-siRNAs allele-selectively inhibit ataxin-3 expression: Multiple mechanisms for an alternative gene silencing strategy
-
Liu J, D Yu, Y Aiba, H Pendergraff, EE Swayze, WF Lima, TP Prakash and DR Corey. (2013). ss-siRNAs allele-selectively inhibit ataxin-3 expression: Multiple mechanisms for an alternative gene silencing strategy. Nucl Acids Res 41: 9570-9583.
-
(2013)
Nucl Acids Res
, vol.41
, pp. 9570-9583
-
-
Liu, J.1
Yu, D.2
Aiba, Y.3
Pendergraff, H.4
Swayze, E.E.5
Lima, W.F.6
Prakash, T.P.7
Corey, D.R.8
-
28
-
-
84904634045
-
Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAs
-
Hu J, J Liu, KJ Narayannair, JG Lackey, S. Kuchimanchi, KG Rajeev, M Manoharan, EE Swayze, WF Lima, et al. (2014). Allele-selective inhibition of mutant atrophin-1 expression by duplex and single-stranded RNAs. Biochemistry 53,4510-4518.
-
(2014)
Biochemistry
, vol.53
, pp. 4510-4518
-
-
Hu, J.1
Liu, J.2
Narayannair, K.J.3
Lackey, J.G.4
Kuchimanchi, S.5
Rajeev, K.G.6
Manoharan, M.7
Swayze, E.E.8
Lima, W.F.9
-
29
-
-
84872589628
-
Transcriptional silencing by single-stranded RNAs targeting a noncoding RNA that overlaps a gene promoter
-
Matsui M, TP Prakash and DR Corey. (2013). Transcriptional silencing by single-stranded RNAs targeting a noncoding RNA that overlaps a gene promoter. ACS Chem Biol 8:122-126.
-
(2013)
ACS Chem Biol
, vol.8
, pp. 122-126
-
-
Matsui, M.1
Prakash, T.P.2
Corey, D.R.3
-
30
-
-
0036823504
-
Targeted exon skipping as a potential gene correction therapy for Duchenne muscular dystrophy
-
Aartsma-Rus A, M Bremmer-Bout, AMM Janson, JT Dunnen, GTB van Ommen and JCT van Deutekom. (2002). Targeted exon skipping as a potential gene correction therapy for Duchenne muscular dystrophy. Neuromuscl Disord 12:S71-S77.
-
(2002)
Neuromuscl Disord
, vol.12
, pp. S71-S77
-
-
Aartsma-Rus, A.1
Bremmer-Bout, M.2
Janson, A.M.M.3
Dunnen, J.T.4
Van Ommen, G.T.B.5
Van Deutekom, J.C.T.6
-
31
-
-
34848904544
-
Comparative analysis of antisense oligonucleotide sequences for targeting skipping of exon 5 during dystrophin pre-mRNA splicing in human muscle
-
Arechavala-Gomeza V, IR Graham, LJ Popplewell, AM Adams, A Aartsma-Rus, M Kinali, JE Morgan, JC Van Deutekom, SD Wilton, G Dickson and F Muntoni. (2007). Comparative analysis of antisense oligonucleotide sequences for targeting skipping of exon 5 during dystrophin pre-mRNA splicing in human muscle. Hum Mol Gene Ther 18:798-810.
-
(2007)
Hum Mol Gene Ther
, vol.18
, pp. 798-810
-
-
Arechavala-Gomeza, V.1
Graham, I.R.2
Popplewell, L.J.3
Adams, A.M.4
Aartsma-Rus, A.5
Kinali, M.6
Morgan, J.E.7
Van Deutekom, J.C.8
Wilton, S.D.9
Dickson, G.10
Muntoni, F.11
-
32
-
-
37549034298
-
Local dystrophin restoration with antisense oligonucleotide PRO051
-
van Deutekom JC, AA Janson, IB Ginjaar, WS Frankhuizen, A Aartsma-Rus, M Bremmer-Bout, JT den Dunnen, K Koop, AJ van der Kooi, et al. (2007). Local dystrophin restoration with antisense oligonucleotide PRO051. New Eng J Med 375:2677-2686.
-
(2007)
New Eng J Med
, vol.375
, pp. 2677-2686
-
-
Van Deutekom, J.C.1
Janson, A.A.2
Ginjaar, I.B.3
Frankhuizen, W.S.4
Aartsma-Rus, A.5
Bremmer-Bout, M.6
Den Dunnen, J.T.7
Koop, K.8
Van Der Kooi, A.J.9
-
33
-
-
78650916689
-
The status of exon skipping as a therapeutic approach to Duchennes muscular dystrophy
-
Lu QL, T Yokota, S Takeda, L Garcia, F Muntoni and T Partridge. (2011). The status of exon skipping as a therapeutic approach to Duchennes muscular dystrophy. Mol Ther 19:9-15.
-
(2011)
Mol Ther
, vol.19
, pp. 9-15
-
-
Lu, Q.L.1
Yokota, T.2
Takeda, S.3
Garcia, L.4
Muntoni, F.5
Partridge, T.6
-
34
-
-
84874970703
-
Targeting mRNA splicing as a potential treatment for Duchenne muscular dystrophy
-
Kole R and BJ Leppert (2012). Targeting mRNA splicing as a potential treatment for Duchenne muscular dystrophy. Discov Med 14:59-69.
-
(2012)
Discov Med
, vol.14
, pp. 59-69
-
-
Kole, R.1
Leppert, B.J.2
-
35
-
-
84907991204
-
Safety and efficacy of drisapersen for the treatment of Duchenne muscular dystrophy (DEMAND II): An exploratory randomised, placebo-controlled phase 2 study
-
Voit T, H Topaloglu, V Straub, F Muntoni, N Deconinck, G Campion, SJ de Kimpe, M Eagle, M Guglieri, et al. (2014). Safety and efficacy of drisapersen for the treatment of Duchenne muscular dystrophy (DEMAND II): an exploratory randomised, placebo-controlled phase 2 study. Lancet Neurol 13:987-996.
-
(2014)
Lancet Neurol
, vol.13
, pp. 987-996
-
-
Voit, T.1
Topaloglu, H.2
Straub, V.3
Muntoni, F.4
Deconinck, N.5
Campion, G.6
De Kimpe, S.J.7
Eagle, M.8
Guglieri, M.9
-
36
-
-
84899120609
-
Exon-skipping therapy: A roadblock, detour, or a bump in the road
-
Hoffman EP and EM Mcnally. (2014). Exon-skipping therapy: a roadblock, detour, or a bump in the road. Sci Transl Med 6:230.
-
(2014)
Sci Transl Med
, vol.6
, pp. 230
-
-
Hoffman, E.P.1
Mcnally, E.M.2
-
37
-
-
4444368187
-
Argonaute 2 is the catalytic engine of RNAi
-
Liu J, MA Carmell, FV Rivas, CG Marsden, JM Thomsen, JJ Song, SM Hammond, L Joshua-Tor and GJ Hannon. (2004). Argonaute 2 is the catalytic engine of RNAi. Science 305:1437-1441.
-
(2004)
Science
, vol.305
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomsen, J.M.5
Song, J.J.6
Hammond, S.M.7
Joshua-Tor, L.8
Hannon, G.J.9
-
38
-
-
57749206034
-
Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex
-
Wang Y, S Juranek, H Li, G Sheng, T Tuschl and DJ Patel. (2008). Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex. Nature 456:921-926.
-
(2008)
Nature
, vol.456
, pp. 921-926
-
-
Wang, Y.1
Juranek, S.2
Li, H.3
Sheng, G.4
Tuschl, T.5
Patel, D.J.6
|