DNA methylation profiles in placenta and its association with gestational diabetes mellitus

Experimental and Clinical Endocrinology and Diabetes

Volumn 123, Issue 5, 2015, Pages 282-288

  Rong, C ^a,b   Cui, X ^b   Chen, J ^b   Qian, Y ^b   Jia, R ^b   Hu, Y ^a  

^a THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^b WOMEN S HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

DNA methylation; gestational diabetes mellitus; microarray; placenta

Indexed keywords

DNA; GLUCOSE TRANSPORTER 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PLASMA RETINOL BINDING PROTEIN; RBP4 PROTEIN, HUMAN; RESISTIN; RETN PROTEIN, HUMAN; SLC2A3 PROTEIN, HUMAN;

ADULT; APOPTOSIS; ARTICLE; CELL GROWTH; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DNA MICROARRAY; ENERGY METABOLISM; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE LOCUS; GENE REGULATORY NETWORK; GENE TARGETING; GENETIC ANALYSIS; GENETIC ASSOCIATION; GLUCOSE TRANSPORTER 3 GENE; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; IMMUNOREGULATION; INFLAMMATION; NERVOUS SYSTEM DEVELOPMENT; PLACENTA; POLYMERASE CHAIN REACTION; PPAR ALPHA GENE; PREGNANCY DIABETES MELLITUS; PREGNANT WOMAN; PRIORITY JOURNAL; PROMOTER REGION; RESISTIN GENE; RETINOL BINDING PROTEIN 4 GENE; SIGNAL TRANSDUCTION; VALIDATION STUDY; CESAREAN SECTION; DOWN REGULATION; GENETICS; METABOLISM; PREGNANCY; THIRD TRIMESTER PREGNANCY; UPREGULATION;

ADULT; CESAREAN SECTION; CPG ISLANDS; DIABETES, GESTATIONAL; DNA METHYLATION; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC LOCI; GLUCOSE TRANSPORTER TYPE 3; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLACENTA; PPAR ALPHA; PREGNANCY; PREGNANCY TRIMESTER, THIRD; PROMOTER REGIONS, GENETIC; RESISTIN; RETINOL-BINDING PROTEINS, PLASMA; UP-REGULATION;

EID: 84929843677     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0034-1398666     Document Type: Article

References (36)

1. Ruchat S. M., Houde A. A., Voisin G. et al. Gestational diabetes mellitus epigenetically affects genes predominantly involved in metabolic diseases. Epigenetics: 2013; 8 935 943
2. Nomura Y., Lambertini L., Rialdi A. et al. Global methylation in the placenta and umbilical cord blood from pregnancies with maternal gestational diabetes, preeclampsia, and obesity. Reproductive Sciences: 2014; 21 131 137
3. Tracy L. S. Gestational diabetes mellitus. Clinical Diabetes: 2004; 23 17 24
4. Burton G. J., Jauniaux E., Charnock-Jones D. S. The influence of the intrauterine environment on human placental development. Int J Dev Biol: 2010; 54 303 312
5. Nelissen E. C., van Montfoort A. P., Dumoulin J. C. et al. Epigenetics and the placenta. Human reproduction update: 2011; 17 397 417
6. Ge Z. J., Liang Q. X., Luo S. M. et al. Diabetic uterus environment may play a key role in alterations of DNA methylation of several imprinted genes at mid-gestation in mice. Reproductive biology and endocrinology: 2013; 11 119
7. Bouchard L., Thibault S., Guay S-P. et al. Leptin gene epigenetic adaptation to impaired glucose metabolism during pregnancy. Diabetes Care: 2010; 33 2436 2441
8. Bouchard L., Hivert M. F., Guay S. P. et al. Placental adiponectin gene DNA methylation levels are associated with mothers' blood glucose concentration. Diabetes: 2012; 61 1272 1280
9. Houde A., St-Pierre J., Hivert M. et al. Placental lipoprotein lipase DNA methylation levels are associated with gestational diabetes mellitus and maternal and cord blood lipid profiles. J Dev Orig Hlth Dis: 2014; 5 132 141
10. American Diabetes Association Diagnosis and classification of diabetes mellitus. Diabetes care: 2010; 33 01 S62 S69
11. Rodenhiser D. I., Andrews J., Kennette W. et al. Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays. Breast cancer research: 2008; 10 1 15
12. th Annual International Conference of the IEEE 2006; IEEE
13. Reiling E., Van't Riet E., Groenewoud M. et al. Combined effects of single-nucleotide polymorphisms in GCK, GCKR, G6PC2 and MTNR1B on fasting plasma glucose and type 2 diabetes risk. Diabetologia: 2009; 52 1866 1870
14. Petry C. J. Gestational diabetes: risk factors and recent advances in its genetics and treatment. Brit J Nutr: 2010; 104 775 787
15. Polakis P. WNT signaling and cancer. Genes & development: 2000; 14 1837 1851
16. Jin T. The WNT signaling pathway and diabetes mellitus. Diabetologia: 2008; 51 1771 1780
17. Buchanan T. A., Xiang A. H. Gestational diabetes mellitus. J Clin Invest: 2005; 115 485 491
18. Wellen K. E., Hotamisligil G. S. Inflammation, stress, and diabetes. J Clin Invest: 2005; 115 1111 1119
19. Schroeder D. I., Blair J. D., Lott P. et al. The human placenta methylome. P Natl Acad Sci USA: 2013; 110 6037 6042
20. Petraglia F., Coukos G., Volpe A. et al. Involvement of placental neurohormones in human parturition. Ann NY Acad Sci: 1991; 622 331 340
21. Yen S. S. The placenta as the third brain. J Reprod Med: 1994; 39 277 280
22. Khoo C. M., Lee K. O. Endocrine emergencies in pregnancy. Best Pract Res Cl Ga: 2013; 27 885 891
23. Dolinoy D. C., Weidman J. R., Jirtle R. L. Epigenetic gene regulation: linking early developmental environment to adult disease. Reprod Toxical: 2007; 23 297 307
24. Novakovic B., Gordon L., Robinson W. P. et al. Glucose as a fetal nutrient: dynamic regulation of several glucose transporter genes by DNA methylation in the human placenta across gestation. J Nutr Biochem: 2013; 24 282 288
25. Yura S., Sagawa N., Itoh H. et al. Resistin is expressed in the human placenta. J Clin Endocr Metab: 2003; 88 1394 1397
26. Steppan C. M., Bailey S. T., Bhat S. et al. The hormone resistin links obesity to diabetes. Nature: 2001; 409 307 312
27. Kuzmicki M., Telejko B., Szamatowicz J. et al. High resistin and interleukin-6 levels are associated with gestational diabetes mellitus. Gynecol Endocrinol: 2009; 25 258 263
28. Duggirala R., Blangero J., Almasy L. et al. Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans. Am J Hum Genet: 1999; 64 1127 1140
29. Su Y. X., Hong J., Yan Q. et al. Increased serum retinol-binding protein-4 levels in pregnant women with and without gestational diabetes mellitus. Diabetes Metab: 2010; 36 470 475
30. Jawerbaum A., Capobianco E. Review: Effects of PPAR activation in the placenta and the fetus: implications in maternal diabetes. Placenta: 2011; 32 02 S212 S217
31. Lee K. J., Shim S. H., Kang K. M. et al. Global gene expression changes induced in the human placenta during labor. Placenta: 2010; 31 698 704
32. Avila L., Yuen R. K., Diego-Alvarez D. et al. Evaluating DNA methylation and gene expression variability in the human term placenta. Placenta: 2010; 31 1070 1077
33. Maier S., Olek A. Diabetes: a candidate disease for efficient DNA methylation profiling. J Nutr: 2002; 132 8 Suppl S2440 S2443
34. Nadler T. S., Stoehr J. P., Schueler K. L. et al. The expression of adipogenic genesis is decreased in obesity and diabetes mellitus. Proc Natl Acad Sci USA: 2000; 97 11371 11376
35. Corominola H., Conner L. J., Beavers L. S. et al. Identification of novel genes differentially expressed in omental fat of obese subjects and obese type 2 diabetic patients. Diabetes: 2001; 50 2822 2830
36. Ducluzeau P. H., Perretti N., Laville M. et al. Regulation by insulin of gene expression in human skeletal muscle and adipose tissue Evidence for specific defects in type 2 diabetes. Diabetes: 2001; 50 1134 1142