Ongoing studies of deimination in neurodegenerative diseases using the F95 antibody

Protein Deimination in Human Health and Disease

Volumn , Issue , 2014, Pages 257-280

  Nicholas, Anthony P ^a   Lu, Liang ^a   Heaven, Michael ^b   Kadish, Inga ^c   Van Groen, Thomas ^c   Accaviti Loper, Mary Ann ^d   Wewering, Sonja ^e   Kofskey, Diane ^f   Gambetti, Pierluigi ^f   Brenner, Michael ^g  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d University of Alabama at Birmingham   (United States)

^e RUHR UNIVERSITY BOCHUM   (Germany)

^f CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g University of Alabama at Birmingham   (United States)

Author keywords

Aging; Alexander disease; Alzheimer's disease; Amyotrophic lateral sclerosis; Creutzfeldt Jakob disease; Diffuse Lewy body disease; Glioma; Parkinson's disease

Indexed keywords

EID: 84929669522     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4614-8317-5_14     Document Type: Chapter

References (40)

1. Acharya NK, Nagele EP, Han M, Coretti NJ, Demarshall C, Kosciuk MC, et al. (2012). Neuronal PAD4 expression and protein citrullination: possible role in production of autoantibodies associated with neurodegenerative disease. J Autoimmun 38: 369-380
2. Akiyama H, Schwab C, Kondo H, Mori H, Kametani F, Ikeda K, et al. (1996). Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-Terminal sequences of -Amyloid protein. Neurosci Lett 206: 169-172
3. Akiyama K, Sakurai Y, Asou H, Senshu T. (1999). Localization of peptidylarginine deiminase type II in a stage-specific immature oligodendrocyte from rat cerebral hemisphere. Neurosci Lett 274: 53-55
4. Andrew SM, Titus JA, Coico R, Amin A. (1997). Purification of immunoglobulin M and immunoglobulin D. Curr Protoc Immunol 21 (Suppl): 2.9.1-2.9.8
5. Bhattacharya SK. (2009). Retinal deimination in aging and disease. IUBMB Life 61: 504-509
6. Borchelt DR, Thinakaran G, Eckman CB, Lee MK, Davenport F, Ratovitsky T, et al. (1996). Familial Alzheimer's disease-linked presenilin 1 variants elevate A1-42/1-40 ratio in vitro and in vivo. Neuron 17: 1005-1013
7. Brenner M, Johnson AB, Boespfl ug-Tanguy O, Rodriguez D, Goldman JE, Messing A. (2001). Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nat Genet 27: 117-120
8. Chang X, Han J. (2006). Expression of peptidylarginine deiminase type 4 (PAD4) in various tumors. Mol Carcinog 45: 183-196
9. De Rycke L, Nicholas AP, Cantaert T, Kruithof E, Echols JD, Vandekerckhove B, et al. (2005). Synovial intracellular citrullinated proteins colocalizing with peptidyl arginine deiminase are pathophysiologically relevant antigenic determinants of rheumatoid arthritis-specific humoral autoimmunity. Arthritis Rheum 52: 2323-2330
10. Eriksen JL, Dawson TM, Dickson DW, Petrucelli L. (2003). Caught in the act: a-synuclein is the culprit in Parkinson's disease. Neuron 40: 453-456
11. Frautschy SA, Cole GM, Baird A. (1992). Phagocytosis and deposition of vascular beta-Amyloid in rat brains injected with Alzheimer beta-Amyloid. Am J Pathol 140: 1389-1399
12. Grant JE, Hu J, Liu T, Jain MR, Elkabes S, Li H. (2007). Post-Translational modifications in the rat lumbar spinal cord in experimental autoimmune encephalomyelitis. J Proteome Res 6: 2786-2791
13. Harauz G, Musse AA. (2007). A tale of two citrullines-structural and functional aspects of myelin basic protein deimination in health and disease. Neurochem Res 32: 137-158
14. Harlow E, Lane DP. (1988). Antibodies: a laboratory manual. Cold Spring Harbor Publishing, New York
15. Ishigami A, Ohsawa T, Hiratsuka M, Taguchi H, Kobayashi S, Saito Y, et al. (2005). Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease. J Neurosci Res 80: 120-128
16. Jang B, Jin JK, Jeon YC, Cho HJ, Ishigami A, Choi KC, et al. (2010). Involvement of peptidylarginine deiminase-mediated post-Translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease. Acta Neuropathol 119: 199-210
17. Keilhoff G, Prell T, Langnaese K, Mawrin C, Simon M, Fansa H, et al. (2008). Expression pattern of peptidylarginine deiminase in rat and human Schwann cells. Dev Neurobiol 68: 101-114
18. Liu L, Ikonen S, Heikkinen T, Tapiola T, van Groen T, Tanila H. (2002). The effects of long-Term treatment with metrifonate, a cholinesterase inhibitor, on cholinergic activity, amyloid pathology, and cognitive function in APP and PS1 doubly transgenic mice. Exp Neurol 173: 196-204
19. Lu L, Wang S, Zheng L, Li X, Suswam EA, Zhang X, et al. (2009). Amyotrophic lateral sclerosislinked mutant SOD1 sequesters Hu antigen R (HuR) and TIA-1-related protein (TIAR): implications for impaired post-Transcriptional regulation of vascular endothelial growth factor. J Biol Chem 284: 33989-33998
20. Ludolph AC, Brettschneider J, Weishaupt JH. (2012). Amyotrophic lateral sclerosis. Curr Opin Neurol 25: 530-535
21. Mendritzki S, Schmidt S, Sczepan T, Zhu XR, Segelcke D, Lübbert H. (2010). Spinal cord pathology in alpha-synuclein transgenic mice. Parkinsons Dis 2010: 375462
22. Messing A, Head MW, Galles K, Galbreath EJ, Goldman JE, Brenner M. (1998). Fatal encephalopathy with astrocyte inclusions in GFAP transgenic mice. Am J Pathol 152: 391-398
23. Morren JA, Galvez-Jimenez N. (2012). Current and prospective disease-modifying therapies for amyotrophic lateral sclerosis. Expert Opin Investig Drugs 21: 297-320
24. Moscarello MA, Wood DD, Ackerly C, Boulias C. (1994). Myelin in multiple sclerosis is developmentally immature. J Clin Invest 94: 146-154
25. Nevens JR, Mallia AK, Wendt MW, Smith PK. (1992). Affinity chromatographic purification of immunoglobulin M antibodies utilizing immobilized mannan binding protein. J Chromatogr 597: 247-256
26. Nicholas AP. (2011). Dual immunofluorescence study of citrullinated proteins in Parkinson diseased substantia nigra. Neurosci Lett 495: 26-29
27. Nicholas AP. (2013). Dual immunofluorescence study of citrullinated proteins in Alzheimer diseased frontal cortex. Neurosci Lett 545: 107-111
28. Nicholas AP, Whitaker JN. (2002). Preparation of a monoclonal antibody to citrullinated epitopes: its characterization and some applications to immunohistochemistry in human brain. Glia 37: 328-336
29. Nicholas AP, King JL, Sambandam T, Echols JD, Gupta KB, McInnis C, et al. (2003). Immunohistochemical localization of citrullinated proteins in adult rat brain. J Comp Neurol 459: 251-266
30. Nicholas AP, Sambandam T, Echols JD, Tourtellotte WW. (2004). Increased citrullinated glial fibrillary acidic protein in secondary progressive multiple sclerosis. J Comp Neurol 473: 128-136
31. Nicholas AP, Sambandam T, Echols JD, Barnum SR. (2005). Expression of citrullinated proteins in murine experimental autoimmune encephalomyelitis. J Comp Neurol 486: 254-266
32. Perng MD, Su M, Wen SF, Li R, Gibbon T, Prescott AR, et al. (2006). The Alexander diseasecausing glial fibrillary acidic protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of aB-crystallin and HSP27. Am J Hum Genet 79: 197-213
33. Sambandam T, Belousova M, Accavitti-Loper MA, Blanquicett C, Guercello V, Raijmakers R, et al. (2004). Increased peptidylarginine deiminase type II in hypoxic astrocytes. Biochem Biophys Res Commun 325: 1324-1329
34. Shimada N, Handa S, Uchida Y, Fukuda M, Maruyama N, Asaga H, et al. (2010). Developmental and age-related changes of peptidylarginine deiminase 2 in the mouse brain. J Neurosci Res 88: 798-806
35. van Groen T, Kiliaan AJ, Kadish I. (2006). Deposition of mouse amyloid in human APP/PS1 double and single AD model transgenic mice. Neurobiol Dis 23: 653-662
36. Van Langenhove T, van der Zee J, Van Broeckhoven C. (2012). The molecular basis of the frontotemporal lobar degeneration-Amyotrophic lateral sclerosis spectrum. Ann Med 44: 817-828
37. Vincent SR, Leung E, Watanabe K. (1992). Immunohistochemical localization of peptidylarginine deiminase in rat brain. J Chem Neuroanat 5: 159-168
38. Wegiel J, Wang KC, Tarnawski M, Lach B. (2000). Microglia cells are the driving force in fibrillar plaque formation, whereas astrocytes are a leading factor in plaque degradation. Acta Neuropathol 100: 356-364
39. Wyss-Coray T, Loike JD, Brionne TC, Lu E, Anankov R, Yan F, et al. (2003). Adult mouse astrocytes degrade amyloid-beta in vitro and in situ. Nat Med 9: 453-457
40. Xu K, Malouf AT, Messing A, Silver J. (1999). Glial fibrillary acidic protein is necessary for mature astrocytes to react to beta-Amyloid. Glia 25: 390-403