Dual immunofluorescence study of citrullinated proteins in Alzheimer diseased frontal cortex

Neuroscience Letters

Volumn 545, Issue , 2013, Pages 107-111

  Nicholas, Anthony P ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

Amyloid beta; Citrulline; Deimination; Glial fibrillary acidic protein; Peptidyl arginine deiminase; Tau

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CITRULLINE; GLIAL FIBRILLARY ACIDIC PROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY F95; NEURON SPECIFIC NUCLEAR PROTEIN; PEPTIDYL CITRULLINE; TAU PROTEIN; UNCLASSIFIED DRUG; VIMENTIN;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ARTICLE; ASTROCYTE; BRAIN CORTEX; CELL STRUCTURE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPLASM; FRONTAL CORTEX; GRAY MATTER; GREAT BLOOD VESSEL; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; NERVE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SENILE PLAQUE; WHITE MATTER;

ALZHEIMER DISEASE; CEREBRAL ARTERIES; CITRULLINE; FLUORESCENT ANTIBODY TECHNIQUE; FRONTAL LOBE; HUMANS; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; NERVE TISSUE PROTEINS; NEURONS; TISSUE DISTRIBUTION;

EID: 84878554880     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.04.028     Document Type: Article

References (38)

1. Acharya N.K., Nagele E.P., Han M., Coretti N.J., Demarshall C., Kosciuk M.C., Boulos P.A., Nagele R.G. Neuronal PAD4 expression and protein citrullination: possible role in production of autoantibodies associated with neurodegenerative disease. J. Autoimmun. 2012, 38:369-380.
2. Akiyama K., Inoue K., Senshu T. Immunocytochemical demonstration of skeletal muscle type peptidylarginine deiminase in various rat tissues. Cell Biol. Int. Rep. 1990, 14:267-273.
3. Asaga H., Ishigami A. Protein deimination in the rat brain: generation of citrulline-containing proteins in cerebrum perfused with oxygen-deprived media. Biomed. Res. 2000, 21:197-205.
4. Asaga H., Senshu T. Combined biochemical and immunocytochemical analyses of postmortem protein deimination in the rat spinal cord. Cell Biol. Int. 1993, 17:525-532.
5. Ballatore C., Lee V.M., Trojanowski J.Q. Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat. Rev. Neurosci. 2007, 8:663-672.
6. Baschong W., Suetterlin R., Laeng R.H. Control of autofluorescence of archival formaldehyde-fixed, paraffin-embedded tissue in confocal laser scanning microscopy (CLSM). J. Histochem. Cytochem. 2001, 49:1565-1571.
7. Bhattacharya S.K., Crabb J.S., Bonilha V.L., Gu X., Takahara H., Crabb J.W. Proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis. Invest. Ophthalmol. Vis. Sci. 2006, 47:2508-2514.
8. Cuthbert G.L., Daujat S., Snowden A.W., Erdjument-Bromage H., Hagiwara T., Yamada M., Schneider R., Gregory P.D., Tempst P., Bannister A.J., Kouzarides T. Histone deimination antagonizes arginine methylation. Cell 2004, 118:545-553.
9. Frackowiak J., Zoltowska A., Wisniewski H.M., Non-fibrillar β-Amyloid protein is associated with smooth muscle cells of vessel walls in Alzheimer disease. J. Neuropathol. Exp. Neurol. 1994, 53:637-645.
10. Frautschy S.A., Cole G.M., Baird A. Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid. Am. J. Pathol. 1992, 140:1389-1399.
11. Giannakopoulos P., Hof P.R., Michel J.P., Guimon J., Bouras C. Cerebral cortex pathology in aging and Alzheimer's disease: a quantitative survey of large hospital-based geriatric and psychiatric cohorts. Brain Res. Rev. 1997, 25:217-245.
12. Grant J.E., Hu J., Liu T., Jain M.R., Elkabes S., Li H. Post-translational modifications in the rat lumbar spinal cord in experimental autoimmune encephalomyelitis. J. Proteome Res. 2007, 6:2786-2791.
13. 2+-dependent deimination-induced disassembly of intermediate filaments involves specific modification of the amino-terminal head domain. J. Biol. Chem. 1989, 264:18119-18127.
14. Ishigami A., Ohsawa T., Hiratsuka M., Taguchi H., Kobayashi S., Saito Y., Murayama S., Asaga H., Toda T., Kimura N., Maruyama N. Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease. J. Neurosci. Res. 2005, 80:120-128.
15. Jang B., Jin J.K., Jeon Y.C., Cho H.J., Ishigami A., Choi K.C., Carp R.I., Maruyama N., Kim Y.S., Choi E.K. Involvement of peptidylarginine deiminase-mediated post-translational citrullination in pathogenesis of sporadic Creutzfeldt-Jakob disease. Acta Neuropathol. 2010, 119:199-210.
16. Jang B., Kim E., Choi J.K., Jin J.K., Kim J.I., Ishigami A., Maruyama N., Carp R.I., Kim Y.S., Choi E.K. Accumulation of citrullinated proteins by up-regulated peptidylarginine deiminase 2 in brains of scrapie-infected mice: a possible role in pathogenesis. Am. J. Pathol. 2008, 173:1129-1142.
17. Kawai M., Kalaria R.N., Cras P., Siedlak S.L., Velasco M.E., Shelton E.R., Chan H.W., Greenberg B.D., Perry G. Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease. Brain Res. 1993, 623:142-146.
18. Keilhoff G., Prell T., Langnaese K., Mawrin C., Simon M., Fansa H., Nicholas A.P. Expression pattern of peptidylarginine deiminase in rat and human Schwann cells. Dev. Neurobiol. 2008, 68:101-114.
19. Lange S., Gögel S., Leung K.Y., Vernay B., Nicholas A.P., Causey C.P., Thompson P.R., Greene N.D., Ferretti P. Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability. Dev. Biol. 2011, 355:205-214.
20. Levenson J.M., Sweatt J.D. Epigenetic mechanisms in memory formation. Nat. Rev. Neurosci. 2005, 6:108-118.
21. Mastronardi F.G., Wood D.D., Mei J., Raijmakers R., Tseveleki V., Dosch H.-M., Probert L., Casaccia-Bonnefil P., Moscarello M.A. Increased citrullination of histone H3 in multiple sclerosis brain and animal models of demyelination: a role for tumor necrosis factor-induced peptidylarginine deiminase 4 translocation. J. Neurosci. 2006, 26:11387-11396.
22. Mi K., Johnson G.V. The role of tau phosphorylation in the pathogenesis of Alzheimer's disease. Curr. Alzheimer Res. 2005, 3:449-463.
23. Moscarello M.A., Pritzker L., Mastronardi F.G., Wood D.D. Peptidylarginine deiminase: a candidate factor in demyelinating disease. J. Neurochem. 2002, 81:335-343.
24. Moscarello M.A., Wood D.D., Ackerly C., Boulias C. Myelin in multiple sclerosis is developmentally immature. J. Clin. Invest. 1994, 94:146-154.
25. Nagele R.G., D'Andrea M.R., Lee H., Venkataraman V., Wang H.-Y. Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains. Brain Res. 2003, 971:197-209.
26. Nicholas A.P. Dual immunofluorescence study of citrullinated proteins in Parkinson diseased substantia nigra. Neurosci. Lett. 2011, 495:26-29.
27. Nicholas A.P., King J.L., Sambandam T., Echols J.D., Gupta K.B., McInnis C., Whitaker J.N. Immunohistochemical localization of citrullinated proteins in adult rat brain. J. Comp. Neurol. 2003, 459:251-266.
28. Nicholas A.P., Sambandam T., Echols J.D., Barnum S.R. Expression of citrullinated proteins in murine experimental autoimmune encephalomyelitis. J. Comp. Neurol. 2005, 486:254-266.
29. Nicholas A.P., Sambandam T., Echols J.D., Tourtellotte W.W. Increased citrullinated glial fibrillary acidic protein in secondary progressive multiple sclerosis. J. Comp. Neurol. 2004, 473:128-136.
30. Nicholas A.P., Whitaker J.N. Preparation of a monoclonal antibody to citrullinated epitopes: its characterization and some applications to immunohistochemistry in human brain. Glia 2002, 37:328-336.
31. Raijmakers R., Vogelzangs J., Croxford J.L., Wesseling P., van Venrooij W.J., Pruijn G.J. Citrullination of central nervous system proteins during the development of experimental autoimmune encephalomyelitis. J. Comp. Neurol. 2005, 486:243-253.
32. Sambandam T., Belousova M., Accavitti-Loper M.A., Blanquicett C., Guercello V., Raijmakers R., Nicholas A.P. Increased peptidylarginine deiminase type II in hypoxic astrocytes. Biochem. Biophys. Res. Commun. 2004, 325:1324-1329.
33. Senshu T., Sato T., Inoue T., Akiyama K., Asaga H. Detection of citrulline residues in deiminated proteins on polyvinylidene difluoride membrane. Anal. Biochem. 1992, 203:94-100.
34. Vincent S.R., Leung E., Watanabe K. Immunohistochemical localization of peptidylarginine deiminase in rat brain. J. Chem. Neuroanat. 1992, 5:159-168.
35. Wegiel J., Wang K.C., Tarnawski M., Lach B. Microglia cells are the driving force in fibrillar plaque formation, whereas astrocytes are a leading factor in plaque degradation. Acta Neuropathol. 2000, 100:356-364.
36. Wood D.D., Bilbao J.M., O'Connors P., Moscarello M.A. Acute multiple sclerosis (Marburg type) is associated with developmentally immature myelin basic protein. Ann. Neurol. 1996, 40:18-24.
37. Wyss-Coray T., Loike J.D., Brionne T.C., Lu E., Anankov R., Yan F., Silverstein S.C., Husemann J. Adult mouse astrocytes degrade amyloid-β in vitro and in situ. Nature Med. 2003, 9:453-457.
38. Xu K., Malouf A.T., Messing A., Silver J. Glial fibrillary acidic protein is necessary for mature astrocytes to react to beta-amyloid. Glia 1999, 25:390-403.