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Volumn 9, Issue 3, 2015, Pages 313-325

Towards understanding mechanisms governing cytotoxicity of metal oxides nanoparticles: Hints from nano-QSAR studies

Author keywords

HaCaT; Nano metal oxides; Nano QSAR; Nanoparticles; Toxicity

Indexed keywords

ALUMINUM; ANTIMONY; BISMUTH; CHROMIUM; COBALT; INDIUM; IRON; LANTHANUM; MANGANESE; METAL OXIDE NANOPARTICLE; NANOPARTICLE; NICKEL; SILICON; TIN; TITANIUM; TUNGSTEN; UNCLASSIFIED DRUG; VANADIUM; YTTRIUM; ZINC; ZIRCONIUM; METAL NANOPARTICLE; OXIDE;

EID: 84929663897     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2014.930195     Document Type: Article
Times cited : (156)

References (84)
  • 1
    • 79961096067 scopus 로고    scopus 로고
    • Effect of gold nanoparticle aggregation on cell uptake and toxicity
    • Albanese A, Chan WCW. 2011. Effect of gold nanoparticle aggregation on cell uptake and toxicity. ACS Nano 5:5478-89.
    • (2011) ACS Nano , vol.5 , pp. 5478-5489
    • Albanese, A.1    Chan, W.C.W.2
  • 2
    • 0027171266 scopus 로고
    • Oxidants, antioxidants, and the degenerative diseases of aging
    • Ames BN, Shigenaga MK, Hagen TM. 1993. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci 90:7915-22.
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 7915-7922
    • Ames, B.N.1    Shigenaga, M.K.2    Hagen, T.M.3
  • 3
    • 84861991267 scopus 로고    scopus 로고
    • Sub-toxic effects of CuO nanoparticles on bacteria: Kinetics, role of Cu ions and possible mechanisms of action
    • Bondarenko O, Ivask A, Käkinen A, Kahru A. 2012. Sub-toxic effects of CuO nanoparticles on bacteria: kinetics, role of Cu ions and possible mechanisms of action. Environ Pollut 169:81-9.
    • (2012) Environ Pollut , vol.169 , pp. 81-89
    • Bondarenko, O.1    Ivask, A.2    Käkinen, A.3    Kahru, A.4
  • 4
    • 27944489615 scopus 로고    scopus 로고
    • In vitro cytotoxicity of nanoparticles in mammalian germline stem cells
    • Braydich-Stolle L, Hussain S, Schlager JJ, Hofmann MC. 2005. In vitro cytotoxicity of nanoparticles in mammalian germline stem cells. Toxicol Sci 88:412-19.
    • (2005) Toxicol Sci , vol.88 , pp. 412-419
    • Braydich-Stolle, L.1    Hussain, S.2    Schlager, J.J.3    Hofmann, M.C.4
  • 5
    • 84872443428 scopus 로고    scopus 로고
    • Development and evaluation of structure-reactivity models for predicting the in vitro oxidative stress of metal oxide nanoparticles
    • In: Puzyn T & Leszczynski J, eds. Cambridge, United Kingdom: Royal Society of Chemistry
    • Burello E, Worth AP. (2012). Development and evaluation of structure-reactivity models for predicting the in vitro oxidative stress of metal oxide nanoparticles. In: Puzyn T & Leszczynski J, eds. Towards Efficient Designing of Safe Nanomaterials: Innovative Merge of Computational Approaches and Experimental Techniques. Cambridge, United Kingdom: Royal Society of Chemistry, 257-83.
    • (2012) Towards Efficient Designing of Safe Nanomaterials: Innovative Merge of Computational Approaches and Experimental Techniques , pp. 257-283
    • Burello, E.1    Worth, A.P.2
  • 6
    • 79957797236 scopus 로고    scopus 로고
    • A theoretical framework for predicting the oxidative stress potential of oxide nanoparticles
    • Burello E, Worth AP. 2011a. A theoretical framework for predicting the oxidative stress potential of oxide nanoparticles. Nanotoxicology 5: 228-35.
    • (2011) Nanotoxicology , vol.5 , pp. 228-235
    • Burello, E.1    Worth, A.P.2
  • 8
    • 0034282468 scopus 로고    scopus 로고
    • Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae
    • Cabiscol E., Piulats E, Echave P, Herrero E, Ros J. 2000. Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae. J Biol Chem 1:27393-8.
    • (2000) J Biol Chem , vol.1 , pp. 27393-27398
    • Cabiscol, E.1    Piulats, E.2    Echave, P.3    Herrero, E.4    Ros, J.5
  • 10
    • 33847789142 scopus 로고    scopus 로고
    • Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles
    • Cedervall T, Lynch I, Lindman S, Berggård T, Thulin E, Nilsson H, et al. 2007. Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles. Proc Natl Acad Sci USA 104:2050-5.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 2050-2055
    • Cedervall, T.1    Lynch, I.2    Lindman, S.3    Berggård, T.4    Thulin, E.5    Nilsson, H.6
  • 11
    • 53549118593 scopus 로고    scopus 로고
    • Selective aggregation mechanism of unmodified gold nanoparticles in detection of single nucleotide polymorphism
    • Cho K, Lee Y, Lee CH, Lee K, Kim Y, Choi H, et al. 2008. Selective aggregation mechanism of unmodified gold nanoparticles in detection of single nucleotide polymorphism. J Phys Chem C 112:8629-33.
    • (2008) J Phys Chem C , vol.112 , pp. 8629-8633
    • Cho, K.1    Lee, Y.2    Lee, C.H.3    Lee, K.4    Kim, Y.5    Choi, H.6
  • 12
    • 84859096802 scopus 로고    scopus 로고
    • Zeta potential and solubility to toxic ions as mechanisms of lung inflammation caused by metal/metal oxide nanoparticles
    • Cho WS, Duffin R, Thielbeer F, Bradley M, Megson LL, MacNee W, et al. 2012. Zeta potential and solubility to toxic ions as mechanisms of lung inflammation caused by metal/metal oxide nanoparticles. Toxicol Sci 126:469-77.
    • (2012) Toxicol Sci , vol.126 , pp. 469-477
    • Cho, W.S.1    Duffin, R.2    Thielbeer, F.3    Bradley, M.4    Megson, L.L.5    Macnee, W.6
  • 15
    • 70349399043 scopus 로고    scopus 로고
    • Copper oxide nanoparticles induce oxidative stress and cytotoxicity in airway epithelial cells
    • Fahmy B, Cormier SA. 2009. Copper oxide nanoparticles induce oxidative stress and cytotoxicity in airway epithelial cells. Toxicol In Vitro 23:1365-71.
    • (2009) Toxicol in Vitro , vol.23 , pp. 1365-1371
    • Fahmy, B.1    Cormier, S.A.2
  • 17
    • 60249101343 scopus 로고    scopus 로고
    • Gene expression profiles in rat lung after inhalation exposure to C 60 fullerene particles
    • Fujita K, Morimoto Y, Ogami A, Myojyo T, Tanaka I, Shimada M, et al. 2009. Gene expression profiles in rat lung after inhalation exposure to C 60 fullerene particles. Toxicology 258:47-55.
    • (2009) Toxicology , vol.258 , pp. 47-55
    • Fujita, K.1    Morimoto, Y.2    Ogami, A.3    Myojyo, T.4    Tanaka, I.5    Shimada, M.6
  • 20
    • 78650682753 scopus 로고    scopus 로고
    • Influence of individual ionic components on the agglomeration kinetics of silver nanoparticles
    • Gebauer JS, Treuel L. 2011. Influence of individual ionic components on the agglomeration kinetics of silver nanoparticles. J Colloid Interface Sci 354:546-54.
    • (2011) J Colloid Interface Sci , vol.354 , pp. 546-554
    • Gebauer, J.S.1    Treuel, L.2
  • 21
    • 34250628103 scopus 로고    scopus 로고
    • Principles of QSAR models validation: Internal and external
    • Gramatica P. 2007. Principles of QSAR models validation: internal and external. QSAR Comb Sci 26:694-701.
    • (2007) QSAR Comb Sci , vol.26 , pp. 694-701
    • Gramatica, P.1
  • 22
    • 84872775982 scopus 로고    scopus 로고
    • QSAR modeling is not ''push a button and find a correlation'': A case study of acute toxicity of (benzo-)triazoles on algae
    • Gramatica P, Cassani C, Roy PP, Kovarich S,Wei YC, Papa E. 2012. QSAR modeling is not ''push a button and find a correlation'': a case study of acute toxicity of (benzo-)triazoles on algae. Mol Inf 31:817-35.
    • (2012) Mol Inf , vol.31 , pp. 817-835
    • Gramatica, P.1    Cassani, C.2    Roy, P.P.3    Kovarich, S.4    Wei, Y.C.5    Papa, E.6
  • 24
    • 44449126091 scopus 로고    scopus 로고
    • The ecotoxicology of nanoparticles and nanomaterials: Current status, knowledge gaps, challenges, and future needs
    • Handy RD, Owen R, Valsami-Jones E. 2008. The ecotoxicology of nanoparticles and nanomaterials: current status, knowledge gaps, challenges, and future needs. Ecotoxicology 17:315-25.
    • (2008) Ecotoxicology , vol.17 , pp. 315-325
    • Handy, R.D.1    Owen, R.2    Valsami-Jones, E.3
  • 26
    • 79959357045 scopus 로고    scopus 로고
    • Toxicity of metal oxides nanoparticles
    • In: Fishbein JC, ed. Oxford: Elsevier
    • Horie M, Fujita K. (2011). Toxicity of metal oxides nanoparticles. In: Fishbein JC, ed. Advances in Molecular Toxicology. Vol. 5. Oxford: Elsevier, 145-78.
    • (2011) Advances in Molecular Toxicology , vol.5 , pp. 145-178
    • Horie, M.1    Fujita, K.2
  • 28
    • 50649117912 scopus 로고    scopus 로고
    • Cellular defenses against superoxide and hydrogen peroxide
    • Imlay JA. 2008. Cellular defenses against superoxide and hydrogen peroxide. Annu Rev Biochem 77:755-76.
    • (2008) Annu Rev Biochem , vol.77 , pp. 755-776
    • Imlay, J.A.1
  • 29
    • 0347303044 scopus 로고    scopus 로고
    • The surface activity of ultrafine particles
    • Jefferson DA. 2000. The surface activity of ultrafine particles. Phil Trans R Soc Lond A 358:2683-92.
    • (2000) Phil Trans R Soc Lond A , vol.358 , pp. 2683-2692
    • Jefferson, D.A.1
  • 30
    • 58149184031 scopus 로고    scopus 로고
    • Characterization of size, surface charge, and agglomeration state of nanoparticle dispersions for toxicological studies
    • Jiang J, Oberdörster G, Biswas P. 2009. Characterization of size, surface charge, and agglomeration state of nanoparticle dispersions for toxicological studies. J Nanopart Res 11:77-99.
    • (2009) J Nanopart Res , vol.11 , pp. 77-99
    • Jiang, J.1    Oberdörster, G.2    Biswas, P.3
  • 31
    • 58149184031 scopus 로고    scopus 로고
    • Characterization of size, surface charge, and agglomeration state of nanoparticle dispersions for toxicological studies
    • Jiang J, Oberdörster G, Biswas P. 2009. Characterization of size, surface charge, and agglomeration state of nanoparticle dispersions for toxicological studies. J Nanopart Res 11:77-89.
    • (2009) J Nanopart Res , vol.11 , pp. 77-89
    • Jiang, J.1    Oberdörster, G.2    Biswas, P.3
  • 33
    • 2342612833 scopus 로고    scopus 로고
    • Size-and temperature-dependent structural transitions in gold nanoparticles
    • 1-4
    • Koga K, Ikeshoji T, Sugawara KI. 2004. Size-and temperature-dependent structural transitions in gold nanoparticles. Phys Rev Lett 92:115507 (1-4).
    • (2004) Phys Rev Lett , vol.92 , pp. 115507
    • Koga, K.1    Ikeshoji, T.2    Sugawara, K.I.3
  • 34
    • 33846852632 scopus 로고    scopus 로고
    • An effective way to stabilize colloidal particles dispersed in polar and non-polar media
    • Kohut A, Voronov A, Peukert W. 2007. An effective way to stabilize colloidal particles dispersed in polar and non-polar media. Langmuir 23:504-8.
    • (2007) Langmuir , vol.23 , pp. 504-508
    • Kohut, A.1    Voronov, A.2    Peukert, W.3
  • 35
    • 84863002431 scopus 로고    scopus 로고
    • Repeated oral dose toxicity of iron oxide nanoparticles: Biochemical and histopathological alterations in different tissues of rats
    • Kumari M, Rajak S, Singh SP, Kumari SI, Kumar PU, Murty USN, et al. 2012. Repeated oral dose toxicity of iron oxide nanoparticles: biochemical and histopathological alterations in different tissues of rats. J Nanosci Nanotechnol 12:2149-59.
    • (2012) J Nanosci Nanotechnol , vol.12 , pp. 2149-2159
    • Kumari, M.1    Rajak, S.2    Singh, S.P.3    Kumari, S.I.4    Kumar, P.U.5    Murty, U.S.N.6
  • 38
    • 28444442646 scopus 로고    scopus 로고
    • Oxide nanoparticle uptake in human lung fibroblasts: Effects of particle size, agglomeration, and diffusion at low concentrations
    • Limbach LK, Li YC, Grass RN, Brunner TJ, Hintermann MA, Muller M, et al. 2005. Oxide nanoparticle uptake in human lung fibroblasts: effects of particle size, agglomeration, and diffusion at low concentrations. Environ Sci Technol 39:9370-6.
    • (2005) Environ Sci Technol , vol.39 , pp. 9370-9376
    • Limbach, L.K.1    Li, Y.C.2    Grass, R.N.3    Brunner, T.J.4    Hintermann, M.A.5    Muller, M.6
  • 39
    • 34250217766 scopus 로고    scopus 로고
    • Exposure of engineered nanoparticles to human lung epithelial cells: Influence of chemical composition and catalytic activity on oxidative stress
    • Limbach LK, Wick P, Manser P, Grass RN, Bruinink A, Stark WJ.2007. Exposure of engineered nanoparticles to human lung epithelial cells: influence of chemical composition and catalytic activity on oxidative stress. Environ Sci Technol 41:4158-63.
    • (2007) Environ Sci Technol , vol.41 , pp. 4158-4163
    • Limbach, L.K.1    Wick, P.2    Manser, P.3    Grass, R.N.4    Bruinink, A.5    Stark, W.J.6
  • 41
    • 33845372148 scopus 로고    scopus 로고
    • Toxicity of cerium oxide nanoparticles in human lung cancer cells
    • Lin W, Huang YW, Zhou XD, Ma Y. 2006. Toxicity of cerium oxide nanoparticles in human lung cancer cells. Int J Toxicol 25:451-7.
    • (2006) Int J Toxicol , vol.25 , pp. 451-457
    • Lin, W.1    Huang, Y.W.2    Zhou, X.D.3    Ma, Y.4
  • 42
    • 61449181236 scopus 로고    scopus 로고
    • Emerging methods and tools for environmental risk assessment, decision-making, and policy for nanomaterials: Summary of NATO Advanced Research Workshop
    • Linkov I, Steevens J, Adlakha-Hutcheon G, Bennett E, Chappell M, Colvin V, et al. 2009. Emerging methods and tools for environmental risk assessment, decision-making, and policy for nanomaterials: summary of NATO Advanced Research Workshop. J Nanopart Res 11:513-27.
    • (2009) J Nanopart Res , vol.11 , pp. 513-527
    • Linkov, I.1    Steevens, J.2    Adlakha-Hutcheon, G.3    Bennett, E.4    Chappell, M.5    Colvin, V.6
  • 43
    • 55749091647 scopus 로고    scopus 로고
    • Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts
    • Lundqvist M, Stigler J, Elia G, Lynch I, Cedervall T, Dawson KA. 2008. Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc Natl Acad Sci USA 105:14265-70.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14265-14270
    • Lundqvist, M.1    Stigler, J.2    Elia, G.3    Lynch, I.4    Cedervall, T.5    Dawson, K.A.6
  • 44
    • 78650725684 scopus 로고    scopus 로고
    • Effects of cell culture media on the dynamic formation of protein-nanoparticle complexes and influence on the cellular response
    • Maiorano G, Sabella S, Sorce B, Brunetti V, Malvindi MA, Cingolani R, Pompa PP. 2010. Effects of cell culture media on the dynamic formation of protein-nanoparticle complexes and influence on the cellular response. ACS Nano 4:7481-91.
    • (2010) ACS Nano , vol.4 , pp. 7481-7491
    • Maiorano, G.1    Sabella, S.2    Sorce, B.3    Brunetti, V.4    Malvindi, M.A.5    Cingolani, R.6    Pompa, P.P.7
  • 45
    • 28844499975 scopus 로고    scopus 로고
    • Airborne nanostructured particles and occupational health
    • Maynard AD, Kuempel ED. 2005. Airborne nanostructured particles and occupational health. J Nanopart Res 7:587-614.
    • (2005) J Nanopart Res , vol.7 , pp. 587-614
    • Maynard, A.D.1    Kuempel, E.D.2
  • 46
    • 68649093091 scopus 로고    scopus 로고
    • A predictive toxicological paradigm for the safety assessment of nanomaterials
    • Meng H, Xia T, George S, Nel AE. 2009. A predictive toxicological paradigm for the safety assessment of nanomaterials. ACS Nano 3: 1620-7.
    • (2009) ACS Nano , vol.3 , pp. 1620-1627
    • Meng, H.1    Xia, T.2    George, S.3    Nel, A.E.4
  • 47
    • 77957165334 scopus 로고    scopus 로고
    • Internalisation of hybrid titanium dioxide/para-amino benzoic acid nanoparticles in human dendritic cells did not induce toxicity and changes in their functions
    • Migdal C, Rahal R, Rubod A, Callejon S, Colomb E, Atrux-Tallau N, et al. 2010. Internalisation of hybrid titanium dioxide/para-amino benzoic acid nanoparticles in human dendritic cells did not induce toxicity and changes in their functions. Toxicol Lett 199:34-42.
    • (2010) Toxicol Lett , vol.199 , pp. 34-42
    • Migdal, C.1    Rahal, R.2    Rubod, A.3    Callejon, S.4    Colomb, E.5    Atrux-Tallau, N.6
  • 48
    • 38149135806 scopus 로고    scopus 로고
    • Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique
    • Murdock RC, Braydich-Stolle L, Schrand AM, Schlager JJ, SM H. 2008. Characterization of nanomaterial dispersion in solution prior to in vitro exposure using dynamic light scattering technique. Toxicol Sci 101: 239-53.
    • (2008) Toxicol Sci , vol.101 , pp. 239-253
    • Murdock, R.C.1    Braydich-Stolle, L.2    Schrand, A.M.3    Schlager, J.J.4
  • 50
    • 0036153806 scopus 로고    scopus 로고
    • Toxicokinetics and effects of fibrous and nonfibrous particles
    • Oberdörster G. 2002. Toxicokinetics and effects of fibrous and nonfibrous particles. Inhal Toxicol 14:29-56.
    • (2002) Inhal Toxicol , vol.14 , pp. 29-56
    • Oberdörster, G.1
  • 51
    • 84921487146 scopus 로고    scopus 로고
    • OECD Principles for the validation, for regulatory purposes, of (Quantittative) Structure Activity Relationship models. 37th Joint Meeting of the Chemicals Committee andWorking Party on Chemicals. Paris, France: Organisation for economic co-operation and development
    • OECD Principles for the validation, for regulatory purposes, of (Quantittative) Structure Activity Relationship models. 37th Joint Meeting of the Chemicals Committee andWorking Party on Chemicals, Pesticides and Biotechnology. 2004. Paris, France: Organisation for economic co-operation and development. Available at: http://www. oecd.org/env/ehs/riskassessment/validationofqsarmodels.html.
    • (2004) Pesticides and Biotechnology
  • 52
    • 79953274470 scopus 로고    scopus 로고
    • Antimicrobial activity and cellular toxicity of nanoparticle-polymyxin B conjugates
    • Park S, Chibli H, Wong J, Nadeau JL. 2011. Antimicrobial activity and cellular toxicity of nanoparticle-polymyxin B conjugates. Nanotechnology 22:185101-10.
    • (2011) Nanotechnology , vol.22 , pp. 185101-185110
    • Park, S.1    Chibli, H.2    Wong, J.3    Nadeau, J.L.4
  • 53
    • 0035216069 scopus 로고    scopus 로고
    • Degenerate semiconductors in the light of electronegativity and chemical hardness
    • Portier J, Campet G, Poquet A, Marcel C, Subramanian MA. 2001. Degenerate semiconductors in the light of electronegativity and chemical hardness. Int J Inorg Mater 3:1039-43.
    • (2001) Int J Inorg Mater , vol.3 , pp. 1039-1043
    • Portier, J.1    Campet, G.2    Poquet, A.3    Marcel, C.4    Subramanian, M.A.5
  • 55
    • 34147191540 scopus 로고    scopus 로고
    • Characterization of the size, shape, and state of dispersion of nanoparticles for toxicological studies
    • Powers KW, Palazuelos M, Moudgil BM, Roberts SM. 2007. Characterization of the size, shape, and state of dispersion of nanoparticles for toxicological studies. Nanotoxicology 1:42-51.
    • (2007) Nanotoxicology , vol.1 , pp. 42-51
    • Powers, K.W.1    Palazuelos, M.2    Moudgil, B.M.3    Roberts, S.M.4
  • 56
    • 77952842146 scopus 로고    scopus 로고
    • Copper nanoparticles exert size and concentration dependent toxicity on somatosensory neurons of rat
    • Prabhu BM, Ali SF, Murdock RC, Hussain SM, Srivatsan M. 2010. Copper nanoparticles exert size and concentration dependent toxicity on somatosensory neurons of rat. Nanotoxicology 4:150-60.
    • (2010) Nanotoxicology , vol.4 , pp. 150-160
    • Prabhu, B.M.1    Ali, S.F.2    Murdock, R.C.3    Hussain, S.M.4    Srivatsan, M.5
  • 58
    • 77955769029 scopus 로고    scopus 로고
    • Surface chemistry and aspect ratio mediated cellular uptake of Au nanorods
    • Qiu Y, Liu Y, Wang L, Xu L, Bai R, Ji Y, et al. 2010. Surface chemistry and aspect ratio mediated cellular uptake of Au nanorods. Biomaterials 31:7606-19.
    • (2010) Biomaterials , vol.31 , pp. 7606-7619
    • Qiu, Y.1    Liu, Y.2    Wang, L.3    Xu, L.4    Bai, R.5    Ji, Y.6
  • 59
    • 78650312249 scopus 로고    scopus 로고
    • Evaluation of nanoparticle aggregation in human blood serum
    • Rausch K, Reuter A, Fischer K, Schmidt M. 2010. Evaluation of nanoparticle aggregation in human blood serum. Biomacromolecules 11:2836-9.
    • (2010) Biomacromolecules , vol.11 , pp. 2836-2839
    • Rausch, K.1    Reuter, A.2    Fischer, K.3    Schmidt, M.4
  • 60
    • 78049323834 scopus 로고    scopus 로고
    • Correlating physico-chemical with toxicological properties of nanoparticles: The present and the future
    • Rivera Gil P, Oberdörster G, Elder A, Puntes V, Parak WJ. 2010. Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future. ACS Nano 4:5527-31.
    • (2010) ACS Nano , vol.4 , pp. 5527-5531
    • Rivera Gil, P.1    Oberdörster, G.2    Elder, A.3    Puntes, V.4    Parak, W.J.5
  • 61
    • 33745452651 scopus 로고    scopus 로고
    • Size matters: Why nanomaterials are different?
    • Roduner E. 2006. Size matters: why nanomaterials are different? Chem Soc Rev 35:583-92.
    • (2006) Chem Soc Rev , vol.35 , pp. 583-592
    • Roduner, E.1
  • 62
    • 84877123509 scopus 로고    scopus 로고
    • Uncertainty in QSAR predictions
    • Sahlin U. 2013. Uncertainty in QSAR predictions. Altern Lab Anim 41: 111-25.
    • (2013) Altern Lab Anim , vol.41 , pp. 111-125
    • Sahlin, U.1
  • 63
    • 84877120272 scopus 로고    scopus 로고
    • Arguments for considering uncertainty in QSAR predictions in hazard and risk assessments
    • Sahlin U, Golsteijn L, Sarfraz MI, Peijnenburg W. 2013. Arguments for considering uncertainty in QSAR predictions in hazard and risk assessments. Altern Lab Anim 41:91-110.
    • (2013) Altern Lab Anim , vol.41 , pp. 91-110
    • Sahlin, U.1    Golsteijn, L.2    Sarfraz, M.I.3    Peijnenburg, W.4
  • 64
    • 52049117672 scopus 로고    scopus 로고
    • Ionic strength and composition affect the mobility of surfacemodified fe0 nanoparticles in water-saturated sand columns
    • Saleh N, Kim H-J, Phenrat T, Matyjaszewski K, Tilton RD, Lovry GV. 2008a. Ionic strength and composition affect the mobility of surfacemodified fe0 nanoparticles in water-saturated sand columns. Environ Sci Technol 42:3349-55.
    • (2008) Environ Sci Technol , vol.42 , pp. 3349-3355
    • Saleh, N.1    Kim, H.-J.2    Phenrat, T.3    Matyjaszewski, K.4    Tilton, R.D.5    Lovry, G.V.6
  • 65
    • 55349109241 scopus 로고    scopus 로고
    • Aggregation kinetics of multiwalled carbon nanotubes in aquatic systems: Measurements and environmental implications
    • Saleh NB, Pfefferle LD, Elimeiech M. 2008b. Aggregation kinetics of multiwalled carbon nanotubes in aquatic systems: measurements and environmental implications. Environ Sci Technol 42:7963-9.
    • (2008) Environ Sci Technol , vol.42 , pp. 7963-7969
    • Saleh, N.B.1    Pfefferle, L.D.2    Elimeiech, M.3
  • 66
    • 77950380428 scopus 로고    scopus 로고
    • Influence of biomacromolecules and humic acid on the aggregation kinetics of single-walled carbon nanotubes
    • Saleh NB, Pfefferle LD, Elimeiech M. 2010. Influence of biomacromolecules and humic acid on the aggregation kinetics of single-walled carbon nanotubes. Environ Sci Technol 44:2412-18.
    • (2010) Environ Sci Technol , vol.44 , pp. 2412-2418
    • Saleh, N.B.1    Pfefferle, L.D.2    Elimeiech, M.3
  • 69
    • 34548164647 scopus 로고    scopus 로고
    • Comparative pulmonary toxicity assessments of C60 water suspensions in rats: Few differences in fullerene toxicity in vivo in contrast to in vitro profiles
    • Sayes CM, Marchione AA, Reed KL, Warheit DB. 2007. Comparative pulmonary toxicity assessments of C60 water suspensions in rats: few differences in fullerene toxicity in vivo in contrast to in vitro profiles. Nano Lett 7:2399-406.
    • (2007) Nano Lett , vol.7 , pp. 2399-2406
    • Sayes, C.M.1    Marchione, A.A.2    Reed, K.L.3    Warheit, D.B.4
  • 71
    • 79959780296 scopus 로고    scopus 로고
    • Experimental and theoretical studies of the colloidal stability of nanoparticles: A general interpretation based on stability maps
    • Segets D, Marczak R, Schäfer S, Paula C, Gnichwitz JF, Hirsch A, Peukert W. 2011. Experimental and theoretical studies of the colloidal stability of nanoparticles: a general interpretation based on stability maps. ACS Nano 5:4658-69.
    • (2011) ACS Nano , vol.5 , pp. 4658-4669
    • Segets, D.1    Marczak, R.2    Schäfer, S.3    Paula, C.4    Gnichwitz, J.F.5    Hirsch, A.6    Peukert, W.7
  • 73
    • 84929686875 scopus 로고    scopus 로고
    • S.C. Chemistry, Editor 2009. (Accessed 02 April 2012)
    • Stewart JJP. 2009. MOPAC2009. S.C. Chemistry, Editor 2009. p. Available at: http://openmopac.net/MOPAC2009.html (Accessed 02 April 2012).
    • (2009) MOPAC2009
    • Stewart, J.J.P.1
  • 74
    • 35448937584 scopus 로고    scopus 로고
    • Optimization of parameters for semiempirical methods. V. Modification of NDDO approximations and application to 70 elements
    • Stewart JJP. 2007. Optimization of parameters for semiempirical methods. V. Modification of NDDO approximations and application to 70 elements. J Mol Model 13:1173-213.
    • (2007) J Mol Model , vol.13 , pp. 1173-1213
    • Stewart, J.J.P.1
  • 75
    • 84872292201 scopus 로고    scopus 로고
    • Optimization of parameters for semi-empirical methods VI: More modifications to the NDDO approximations and re-optimization of parameters
    • Stewart JJP. 2013. Optimization of parameters for semi-empirical methods VI: more modifications to the NDDO approximations and re-optimization of parameters. J Mol Model 19:1-32.
    • (2013) J Mol Model , vol.19 , pp. 1-32
    • Stewart, J.J.P.1
  • 76
    • 0028798434 scopus 로고
    • Oxidative mechanisms in the toxicity of metal ions
    • Stohs SJ, Bagchi D. 1995. Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med 18:321-36.
    • (1995) Free Radic Biol Med , vol.18 , pp. 321-336
    • Stohs, S.J.1    Bagchi, D.2
  • 77
    • 0038724207 scopus 로고    scopus 로고
    • The importance of being earnest: Validation is the absolute essential for successful application and interpretation of QSPR models
    • Tropsha A, Gramatica P, Gombar VK. 2003. The importance of being earnest: Validation is the absolute essential for successful application and interpretation of QSPR models. QSAR Comb Sci 22: 69-77.
    • (2003) QSAR Comb Sci , vol.22 , pp. 69-77
    • Tropsha, A.1    Gramatica, P.2    Gombar, V.K.3
  • 78
    • 84896348692 scopus 로고    scopus 로고
    • Immunotoxicity of nanoparticles: Computational study suggests that CNTs and C60 fullerenes might be recognized as pathogens by Toll-like receptors
    • Turabekova M, Rasulev B, Theodor M, Jackman J, Leszczynska D, Leszczynski J. 2014. Immunotoxicity of nanoparticles: computational study suggests that CNTs and C60 fullerenes might be recognized as pathogens by Toll-like receptors. Nanoscale 6:3488-95.
    • (2014) Nanoscale , vol.6 , pp. 3488-3495
    • Turabekova, M.1    Rasulev, B.2    Theodor, M.3    Jackman, J.4    Leszczynska, D.5    Leszczynski, J.6
  • 79
    • 0142150051 scopus 로고    scopus 로고
    • Mitochondrial formation of reactive oxygen spicies
    • Turrens JF. 2003. Mitochondrial formation of reactive oxygen spicies. J Physiol 552:335-44.
    • (2003) J Physiol , vol.552 , pp. 335-344
    • Turrens, J.F.1
  • 80
    • 84895855470 scopus 로고    scopus 로고
    • Cuprous oxide nanoparticles inhibit growth and metastasis of melanoma by targeting mitochondria
    • Wang Y, Yang F, Zhang X-H, Zi X-Y, Pan X-H, Chen F, et al. 2013. Cuprous oxide nanoparticles inhibit growth and metastasis of melanoma by targeting mitochondria. Cell Death Dis 4:e783. doi: 10.1038/ cddis.2013.314.
    • (2013) Cell Death Dis , vol.4 , pp. e783
    • Wang, Y.1    Yang, F.2    Zhang, X.-H.3    Zi, X.-Y.4    Pan, X.-H.5    Chen, F.6
  • 82
    • 84885757504 scopus 로고    scopus 로고
    • Applying quantitative structure-activity relationship approaches to nanotoxicology: Current status and future potential
    • Winklera DA, Mombelli E, Pietroiusti A, Tran L, Worth A, Fadeel B, McCall MJ. 2013. Applying quantitative structure-activity relationship approaches to nanotoxicology: current status and future potential. Toxicology 313:15-23.
    • (2013) Toxicology , vol.313 , pp. 15-23
    • Winklera, D.A.1    Mombelli, E.2    Pietroiusti, A.3    Tran, L.4    Worth, A.5    Fadeel, B.6    McCall, M.J.7
  • 83
    • 84862846212 scopus 로고    scopus 로고
    • Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation
    • Zhang H, Ji Z, Xia T, Meng H, Low-Kam C, Liu R, et al. 2012. Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation. ACS Nano 6: 4349-68.
    • (2012) ACS Nano , vol.6 , pp. 4349-4368
    • Zhang, H.1    Ji, Z.2    Xia, T.3    Meng, H.4    Low-Kam, C.5    Liu, R.6
  • 84
    • 80655144964 scopus 로고    scopus 로고
    • Stable nanoparticle aggregates/agglomerates of different sizes and the effect of their size on hemolytic cytotoxicity
    • Zook JM, MacCuspie RI, Locascio LE, Halter MD, Elliott JT. 2011. Stable nanoparticle aggregates/agglomerates of different sizes and the effect of their size on hemolytic cytotoxicity. Nanotoxicology 5: 517-30.
    • (2011) Nanotoxicology , vol.5 , pp. 517-530
    • Zook, J.M.1    Maccuspie, R.I.2    Locascio, L.E.3    Halter, M.D.4    Elliott, J.T.5


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