-
1
-
-
0013462065
-
A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes
-
Moyzis RK, Buckingham JM, Cram LS, et al: A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes. Proc Natl Acad Sci USA 1988; 85:6622–6626
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 6622-6626
-
-
Moyzis, R.K.1
Buckingham, J.M.2
Cram, L.S.3
-
2
-
-
0015844590
-
A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon
-
Olovnikov AM: A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. J Theor Biol 1973; 41: 181–190
-
(1973)
J Theor Biol
, vol.41
, pp. 181-190
-
-
Olovnikov, A.M.1
-
3
-
-
39749173730
-
Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer’s disease
-
Thomas P, O’ Callaghan NJ, Fenech M: Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer’s disease. Mech Ageing Dev 2008; 129:183–190
-
(2008)
Mech Ageing Dev
, vol.129
, pp. 183-190
-
-
Thomas, P.1
O’ Callaghan, N.J.2
Fenech, M.3
-
4
-
-
0029681361
-
Accelerated telomere shortening in ataxia telangiectasia
-
Metcalfe JA, Parkhill J, Campbell L, et al: Accelerated telomere shortening in ataxia telangiectasia. Nat Genet 1996; 13:350–353
-
(1996)
Nat Genet
, vol.13
, pp. 350-353
-
-
Metcalfe, J.A.1
Parkhill, J.2
Campbell, L.3
-
5
-
-
34548430918
-
Intrinsic mitochondrial dysfunction in ATM-deficient lymphoblastoid cells
-
Ambrose M, Goldstine JV, Gatti RA: Intrinsic mitochondrial dysfunction in ATM-deficient lymphoblastoid cells. Hum Mol Genet 2007; 16:2154–2164
-
(2007)
Hum Mol Genet
, vol.16
, pp. 2154-2164
-
-
Ambrose, M.1
Goldstine, J.V.2
Gatti, R.A.3
-
6
-
-
84856893251
-
Mitochondrial dysfunction in ataxia-telangiectasia
-
Valentin-Vega YA, Maclean KH, Tait-Mulder J, et al: Mitochondrial dysfunction in ataxia-telangiectasia. Blood 2012; 119:1490–1500
-
(2012)
Blood
, vol.119
, pp. 1490-1500
-
-
Valentin-Vega, Y.A.1
Maclean, K.H.2
Tait-Mulder, J.3
-
7
-
-
33749042331
-
Transcriptional repression of PGC-1aby mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
-
Cui L, Jeong H, Borovecki F, et al: Transcriptional repression of PGC-1a by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell 2006; 127:59–69
-
(2006)
Cell
, vol.127
, pp. 59-69
-
-
Cui, L.1
Jeong, H.2
Borovecki, F.3
-
8
-
-
62149107892
-
DNA damage and repair in Alzheimer’s disease
-
Coppedè F, Migliore L: DNA damage and repair in Alzheimer’s disease. Curr Alzheimer Res 2009; 6:36–47
-
(2009)
Curr Alzheimer Res
, vol.6
, pp. 36-47
-
-
Coppedè, F.1
Migliore, L.2
-
9
-
-
84861461464
-
Axis of ageing: Telomeres, p53 and mitochondria
-
Sahin E, DePinho RA: Axis of ageing: telomeres, p53 and mitochondria. Nat Rev Mol Cell Biol 2012; 13:397–404
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 397-404
-
-
Sahin, E.1
Depinho, R.A.2
-
10
-
-
79951812916
-
Telomere dysfunction induces metabolic and mitochondrial compromise
-
Sahin E, Colla S, Liesa M, et al: Telomere dysfunction induces metabolic and mitochondrial compromise. Nature 2011; 470: 359–365
-
(2011)
Nature
, vol.470
, pp. 359-365
-
-
Sahin, E.1
Colla, S.2
Liesa, M.3
-
11
-
-
84861325995
-
Molecular neuropathogenesis of Alzheimer’s disease: An interaction model stressing the central role of oxidative stress
-
Rodrigues R, Smith MA, Wang X, et al: Molecular neuropathogenesis of Alzheimer’s disease: an interaction model stressing the central role of oxidative stress. Future Neurol 2012; 7:287–305
-
(2012)
Future Neurol
, vol.7
, pp. 287-305
-
-
Rodrigues, R.1
Smith, M.A.2
Wang, X.3
-
12
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Lin MT, Beal MF: Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006; 443:787–795
-
(2006)
Nature
, vol.443
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
14
-
-
2342419515
-
Telomere measurement by quantitative PCR
-
Cawthon RM: Telomere measurement by quantitative PCR. Nucleic Acids Res 2002; 30:e47
-
(2002)
Nucleic Acids Res
, pp. 30
-
-
Cawthon, R.M.1
-
15
-
-
0141454795
-
Molecular analysis of Huntington’s disease and linked polymorphisms in the Indian population
-
Saleem Q, Roy S, Murgood U, et al: Molecular analysis of Huntington’s disease and linked polymorphisms in the Indian population. Acta Neurol Scand 2003; 108:281–286
-
(2003)
Acta Neurol Scand
, vol.108
, pp. 281-286
-
-
Saleem, Q.1
Roy, S.2
Murgood, U.3
-
16
-
-
0029067940
-
A hindi version of the MMSE: The development of a cognitive screening instrument for a largely illiterate rural elderly population in India
-
Ganguli M, Ratcliff G, Chandra V, et al: A hindi version of the MMSE: The development of a cognitive screening instrument for a largely illiterate rural elderly population in India. Int J Geriatr Psychiatry 1995; 10:367–377
-
(1995)
Int J Geriatr Psychiatry
, vol.10
, pp. 367-377
-
-
Ganguli, M.1
Ratcliff, G.2
Chandra, V.3
-
17
-
-
0024284028
-
A simple salting out procedure for extracting DNA from human nucleated cells
-
Miller SA, Dykes DD, Polesky HF: A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16:1215
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 1215
-
-
Miller, S.A.1
Dykes, D.D.2
Polesky, H.F.3
-
18
-
-
24644465053
-
The R commander: A basic-statistics graphical user interface to R
-
Fox J: The R commander: a basic-statistics graphical user interface to R. J Stat Softw 2005; 14:1–42
-
(2005)
J Stat Softw
, vol.14
, pp. 1-42
-
-
Fox, J.1
-
20
-
-
84862181593
-
T-tests, non-parametric tests, and large studies— a paradox of statistical practice?
-
Fagerland MW: t-tests, non-parametric tests, and large studies— a paradox of statistical practice? BMCMed Res Methodol 2012; 12:78
-
(2012)
Bmcmed Res Methodol
, vol.12
, pp. 78
-
-
Fagerland, M.W.1
-
21
-
-
0035908777
-
Mann-Whitney test is not just a test of medians: Differences in spread can be important
-
Hart A: Mann-Whitney test is not just a test of medians: differences in spread can be important. BMJ 2001; 323:391–393
-
(2001)
BMJ
, vol.323
, pp. 391-393
-
-
Hart, A.1
-
22
-
-
84866925330
-
Downregulation of genes involved in metabolism and oxidative stress in the peripheral leukocytes of Huntington’s disease patients
-
Chang K-H, Chen Y-C, Wu Y-R, et al: Downregulation of genes involved in metabolism and oxidative stress in the peripheral leukocytes of Huntington’s disease patients. PLoS ONE 2012; 7: e46492
-
(2012)
Plos ONE
, vol.7
-
-
Chang, K.-H.1
Chen, Y.-C.2
Wu, Y.-R.3
-
23
-
-
23344448837
-
Genome-wide expression profiling of human blood reveals biomarkers for Huntington’s disease
-
Borovecki F, Lovrecic L, Zhou J, et al: Genome-wide expression profiling of human blood reveals biomarkers for Huntington’s disease. Proc Natl Acad Sci USA 2005; 102:11023–11028
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 11023-11028
-
-
Borovecki, F.1
Lovrecic, L.2
Zhou, J.3
-
24
-
-
84864526960
-
European Huntington Disease Network: A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset
-
Soyal SM, Felder TK, Auer S, et al; European Huntington Disease Network: A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset. Hum Mol Genet 2012; 21:3461–3473
-
(2012)
Hum Mol Genet
, vol.21
, pp. 3461-3473
-
-
Soyal, S.M.1
Felder, T.K.2
Auer, S.3
-
25
-
-
84856211181
-
Telomere length is agedependent and reduced in monocytes of Alzheimer patients
-
Hochstrasser T, Marksteiner J, Humpel C: Telomere length is agedependent and reduced in monocytes of Alzheimer patients. Exp Gerontol 2012; 47:160–163
-
(2012)
Exp Gerontol
, vol.47
, pp. 160-163
-
-
Hochstrasser, T.1
Marksteiner, J.2
Humpel, C.3
-
26
-
-
0033747604
-
Short telomeres in patients with vascular dementia: An indicator of low antioxidative capacity and a possible risk factor?
-
von Zglinicki T, Serra V, Lorenz M, et al: Short telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor? Lab Invest 2000; 80: 1739–1747
-
(2000)
Lab Invest
, vol.80
, pp. 1739-1747
-
-
Von Zglinicki, T.1
Serra, V.2
Lorenz, M.3
-
27
-
-
46049085018
-
Shorter telomeres may mark early risk of dementia: Preliminary analysis of 62 participants from the Nurses’ Health Study
-
Grodstein F, van Oijen M, Irizarry MC, et al.: Shorter telomeres may mark early risk of dementia: preliminary analysis of 62 participants from the Nurses’ Health Study. PLoS ONE 2008; 3: e1590
-
(2008)
Plos ONE
, vol.3
-
-
Grodstein, F.1
Van Oijen, M.2
Irizarry, M.C.3
-
28
-
-
84867346421
-
Association of shorter leukocyte telomere repeat length with dementia and mortality
-
Honig LS, Kang MS, Schupf N, et al: Association of shorter leukocyte telomere repeat length with dementia and mortality. Arch Neurol 2012; 69:1332–1339
-
(2012)
Arch Neurol
, vol.69
, pp. 1332-1339
-
-
Honig, L.S.1
Kang, M.S.2
Schupf, N.3
-
29
-
-
0036629255
-
Oxidative stress shortens telomeres
-
von Zglinicki T: Oxidative stress shortens telomeres. Trends Biochem Sci 2002; 27:339–344
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 339-344
-
-
Von Zglinicki, T.1
-
30
-
-
38749084157
-
Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia
-
Gackowski D, Rozalski R, Siomek A, et al: Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia. J Neurol Sci 2008; 266:57–62
-
(2008)
J Neurol Sci
, vol.266
, pp. 57-62
-
-
Gackowski, D.1
Rozalski, R.2
Siomek, A.3
-
31
-
-
84888198610
-
DNA methylation and Alzheimer’s disease
-
Edited by Tollefsbol TO. New York, Springer
-
van Groen T: DNA methylation and Alzheimer’s disease, in Epigenetics of Aging. Edited by Tollefsbol TO. New York, Springer, 2010, pp 315–326
-
(2010)
Epigenetics of Aging
, pp. 315-326
-
-
Van Groen, T.1
-
32
-
-
33947317206
-
The epigenetic regulation of mammalian telomeres
-
Blasco MA: The epigenetic regulation of mammalian telomeres. Nat Rev Genet 2007; 8:299–309
-
(2007)
Nat Rev Genet
, vol.8
, pp. 299-309
-
-
Blasco, M.A.1
-
34
-
-
84860510280
-
Disease-specific phenotypes in dopamine neurons from human iPSbased models of genetic and sporadic Parkinson’s disease
-
Sánchez-Danés A, Richaud-Patin Y, Carballo-Carbajal I, et al: Disease-specific phenotypes in dopamine neurons from human iPSbased models of genetic and sporadic Parkinson’s disease. EMBOMol Med 2012; 4:380–395
-
(2012)
Embomol Med
, vol.4
, pp. 380-395
-
-
Sánchez-Danés, A.1
Richaud-Patin, Y.2
Carballo-Carbajal, I.3
-
35
-
-
78650990326
-
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
-
Jaskelioff M, Muller FL, Paik J-H, et al: Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature 2011; 469:102–106
-
(2011)
Nature
, vol.469
, pp. 102-106
-
-
Jaskelioff, M.1
Muller, F.L.2
Paik, J.-H.3
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