메뉴 건너뛰기




Volumn 27, Issue 2, 2015, Pages e92-e96

Reduced telomere length in neurodegenerative disorders may suggest shared biology

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; ASSESSMENT OF HUMANS; ATAXIA TELANGIECTASIA; BIOLOGY; CAG REPEAT; CELL AGING; COMPARATIVE STUDY; CONTROLLED STUDY; DEGENERATIVE DISEASE; DEMENTIA; FEMALE; HINDI MENTAL STATUS EXAMINATION SCALE; HUMAN; HUNTINGTON CHOREA; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PHENOTYPE; PRIORITY JOURNAL; TELOMERE; TELOMERE LENGTH; ADOLESCENT; CHILD; CLASSIFICATION; COMPLICATION; GENETICS; MIDDLE AGED; TELOMERE SHORTENING;

EID: 84929662223     PISSN: 08950172     EISSN: 15457222     Source Type: Journal    
DOI: 10.1176/appi.neuropsych.13100240     Document Type: Article
Times cited : (43)

References (35)
  • 1
    • 0013462065 scopus 로고
    • A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes
    • Moyzis RK, Buckingham JM, Cram LS, et al: A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes. Proc Natl Acad Sci USA 1988; 85:6622–6626
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 6622-6626
    • Moyzis, R.K.1    Buckingham, J.M.2    Cram, L.S.3
  • 2
    • 0015844590 scopus 로고
    • A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon
    • Olovnikov AM: A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon. J Theor Biol 1973; 41: 181–190
    • (1973) J Theor Biol , vol.41 , pp. 181-190
    • Olovnikov, A.M.1
  • 3
    • 39749173730 scopus 로고    scopus 로고
    • Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer’s disease
    • Thomas P, O’ Callaghan NJ, Fenech M: Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer’s disease. Mech Ageing Dev 2008; 129:183–190
    • (2008) Mech Ageing Dev , vol.129 , pp. 183-190
    • Thomas, P.1    O’ Callaghan, N.J.2    Fenech, M.3
  • 4
    • 0029681361 scopus 로고    scopus 로고
    • Accelerated telomere shortening in ataxia telangiectasia
    • Metcalfe JA, Parkhill J, Campbell L, et al: Accelerated telomere shortening in ataxia telangiectasia. Nat Genet 1996; 13:350–353
    • (1996) Nat Genet , vol.13 , pp. 350-353
    • Metcalfe, J.A.1    Parkhill, J.2    Campbell, L.3
  • 5
    • 34548430918 scopus 로고    scopus 로고
    • Intrinsic mitochondrial dysfunction in ATM-deficient lymphoblastoid cells
    • Ambrose M, Goldstine JV, Gatti RA: Intrinsic mitochondrial dysfunction in ATM-deficient lymphoblastoid cells. Hum Mol Genet 2007; 16:2154–2164
    • (2007) Hum Mol Genet , vol.16 , pp. 2154-2164
    • Ambrose, M.1    Goldstine, J.V.2    Gatti, R.A.3
  • 6
    • 84856893251 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in ataxia-telangiectasia
    • Valentin-Vega YA, Maclean KH, Tait-Mulder J, et al: Mitochondrial dysfunction in ataxia-telangiectasia. Blood 2012; 119:1490–1500
    • (2012) Blood , vol.119 , pp. 1490-1500
    • Valentin-Vega, Y.A.1    Maclean, K.H.2    Tait-Mulder, J.3
  • 7
    • 33749042331 scopus 로고    scopus 로고
    • Transcriptional repression of PGC-1aby mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
    • Cui L, Jeong H, Borovecki F, et al: Transcriptional repression of PGC-1a by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell 2006; 127:59–69
    • (2006) Cell , vol.127 , pp. 59-69
    • Cui, L.1    Jeong, H.2    Borovecki, F.3
  • 8
    • 62149107892 scopus 로고    scopus 로고
    • DNA damage and repair in Alzheimer’s disease
    • Coppedè F, Migliore L: DNA damage and repair in Alzheimer’s disease. Curr Alzheimer Res 2009; 6:36–47
    • (2009) Curr Alzheimer Res , vol.6 , pp. 36-47
    • Coppedè, F.1    Migliore, L.2
  • 9
    • 84861461464 scopus 로고    scopus 로고
    • Axis of ageing: Telomeres, p53 and mitochondria
    • Sahin E, DePinho RA: Axis of ageing: telomeres, p53 and mitochondria. Nat Rev Mol Cell Biol 2012; 13:397–404
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 397-404
    • Sahin, E.1    Depinho, R.A.2
  • 10
    • 79951812916 scopus 로고    scopus 로고
    • Telomere dysfunction induces metabolic and mitochondrial compromise
    • Sahin E, Colla S, Liesa M, et al: Telomere dysfunction induces metabolic and mitochondrial compromise. Nature 2011; 470: 359–365
    • (2011) Nature , vol.470 , pp. 359-365
    • Sahin, E.1    Colla, S.2    Liesa, M.3
  • 11
    • 84861325995 scopus 로고    scopus 로고
    • Molecular neuropathogenesis of Alzheimer’s disease: An interaction model stressing the central role of oxidative stress
    • Rodrigues R, Smith MA, Wang X, et al: Molecular neuropathogenesis of Alzheimer’s disease: an interaction model stressing the central role of oxidative stress. Future Neurol 2012; 7:287–305
    • (2012) Future Neurol , vol.7 , pp. 287-305
    • Rodrigues, R.1    Smith, M.A.2    Wang, X.3
  • 12
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • Lin MT, Beal MF: Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 2006; 443:787–795
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 14
    • 2342419515 scopus 로고    scopus 로고
    • Telomere measurement by quantitative PCR
    • Cawthon RM: Telomere measurement by quantitative PCR. Nucleic Acids Res 2002; 30:e47
    • (2002) Nucleic Acids Res , pp. 30
    • Cawthon, R.M.1
  • 15
    • 0141454795 scopus 로고    scopus 로고
    • Molecular analysis of Huntington’s disease and linked polymorphisms in the Indian population
    • Saleem Q, Roy S, Murgood U, et al: Molecular analysis of Huntington’s disease and linked polymorphisms in the Indian population. Acta Neurol Scand 2003; 108:281–286
    • (2003) Acta Neurol Scand , vol.108 , pp. 281-286
    • Saleem, Q.1    Roy, S.2    Murgood, U.3
  • 16
    • 0029067940 scopus 로고
    • A hindi version of the MMSE: The development of a cognitive screening instrument for a largely illiterate rural elderly population in India
    • Ganguli M, Ratcliff G, Chandra V, et al: A hindi version of the MMSE: The development of a cognitive screening instrument for a largely illiterate rural elderly population in India. Int J Geriatr Psychiatry 1995; 10:367–377
    • (1995) Int J Geriatr Psychiatry , vol.10 , pp. 367-377
    • Ganguli, M.1    Ratcliff, G.2    Chandra, V.3
  • 17
    • 0024284028 scopus 로고
    • A simple salting out procedure for extracting DNA from human nucleated cells
    • Miller SA, Dykes DD, Polesky HF: A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16:1215
    • (1988) Nucleic Acids Res , vol.16 , pp. 1215
    • Miller, S.A.1    Dykes, D.D.2    Polesky, H.F.3
  • 18
    • 24644465053 scopus 로고    scopus 로고
    • The R commander: A basic-statistics graphical user interface to R
    • Fox J: The R commander: a basic-statistics graphical user interface to R. J Stat Softw 2005; 14:1–42
    • (2005) J Stat Softw , vol.14 , pp. 1-42
    • Fox, J.1
  • 20
    • 84862181593 scopus 로고    scopus 로고
    • T-tests, non-parametric tests, and large studies— a paradox of statistical practice?
    • Fagerland MW: t-tests, non-parametric tests, and large studies— a paradox of statistical practice? BMCMed Res Methodol 2012; 12:78
    • (2012) Bmcmed Res Methodol , vol.12 , pp. 78
    • Fagerland, M.W.1
  • 21
    • 0035908777 scopus 로고    scopus 로고
    • Mann-Whitney test is not just a test of medians: Differences in spread can be important
    • Hart A: Mann-Whitney test is not just a test of medians: differences in spread can be important. BMJ 2001; 323:391–393
    • (2001) BMJ , vol.323 , pp. 391-393
    • Hart, A.1
  • 22
    • 84866925330 scopus 로고    scopus 로고
    • Downregulation of genes involved in metabolism and oxidative stress in the peripheral leukocytes of Huntington’s disease patients
    • Chang K-H, Chen Y-C, Wu Y-R, et al: Downregulation of genes involved in metabolism and oxidative stress in the peripheral leukocytes of Huntington’s disease patients. PLoS ONE 2012; 7: e46492
    • (2012) Plos ONE , vol.7
    • Chang, K.-H.1    Chen, Y.-C.2    Wu, Y.-R.3
  • 23
    • 23344448837 scopus 로고    scopus 로고
    • Genome-wide expression profiling of human blood reveals biomarkers for Huntington’s disease
    • Borovecki F, Lovrecic L, Zhou J, et al: Genome-wide expression profiling of human blood reveals biomarkers for Huntington’s disease. Proc Natl Acad Sci USA 2005; 102:11023–11028
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 11023-11028
    • Borovecki, F.1    Lovrecic, L.2    Zhou, J.3
  • 24
    • 84864526960 scopus 로고    scopus 로고
    • European Huntington Disease Network: A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset
    • Soyal SM, Felder TK, Auer S, et al; European Huntington Disease Network: A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset. Hum Mol Genet 2012; 21:3461–3473
    • (2012) Hum Mol Genet , vol.21 , pp. 3461-3473
    • Soyal, S.M.1    Felder, T.K.2    Auer, S.3
  • 25
    • 84856211181 scopus 로고    scopus 로고
    • Telomere length is agedependent and reduced in monocytes of Alzheimer patients
    • Hochstrasser T, Marksteiner J, Humpel C: Telomere length is agedependent and reduced in monocytes of Alzheimer patients. Exp Gerontol 2012; 47:160–163
    • (2012) Exp Gerontol , vol.47 , pp. 160-163
    • Hochstrasser, T.1    Marksteiner, J.2    Humpel, C.3
  • 26
    • 0033747604 scopus 로고    scopus 로고
    • Short telomeres in patients with vascular dementia: An indicator of low antioxidative capacity and a possible risk factor?
    • von Zglinicki T, Serra V, Lorenz M, et al: Short telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor? Lab Invest 2000; 80: 1739–1747
    • (2000) Lab Invest , vol.80 , pp. 1739-1747
    • Von Zglinicki, T.1    Serra, V.2    Lorenz, M.3
  • 27
    • 46049085018 scopus 로고    scopus 로고
    • Shorter telomeres may mark early risk of dementia: Preliminary analysis of 62 participants from the Nurses’ Health Study
    • Grodstein F, van Oijen M, Irizarry MC, et al.: Shorter telomeres may mark early risk of dementia: preliminary analysis of 62 participants from the Nurses’ Health Study. PLoS ONE 2008; 3: e1590
    • (2008) Plos ONE , vol.3
    • Grodstein, F.1    Van Oijen, M.2    Irizarry, M.C.3
  • 28
    • 84867346421 scopus 로고    scopus 로고
    • Association of shorter leukocyte telomere repeat length with dementia and mortality
    • Honig LS, Kang MS, Schupf N, et al: Association of shorter leukocyte telomere repeat length with dementia and mortality. Arch Neurol 2012; 69:1332–1339
    • (2012) Arch Neurol , vol.69 , pp. 1332-1339
    • Honig, L.S.1    Kang, M.S.2    Schupf, N.3
  • 29
    • 0036629255 scopus 로고    scopus 로고
    • Oxidative stress shortens telomeres
    • von Zglinicki T: Oxidative stress shortens telomeres. Trends Biochem Sci 2002; 27:339–344
    • (2002) Trends Biochem Sci , vol.27 , pp. 339-344
    • Von Zglinicki, T.1
  • 30
    • 38749084157 scopus 로고    scopus 로고
    • Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia
    • Gackowski D, Rozalski R, Siomek A, et al: Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia. J Neurol Sci 2008; 266:57–62
    • (2008) J Neurol Sci , vol.266 , pp. 57-62
    • Gackowski, D.1    Rozalski, R.2    Siomek, A.3
  • 31
    • 84888198610 scopus 로고    scopus 로고
    • DNA methylation and Alzheimer’s disease
    • Edited by Tollefsbol TO. New York, Springer
    • van Groen T: DNA methylation and Alzheimer’s disease, in Epigenetics of Aging. Edited by Tollefsbol TO. New York, Springer, 2010, pp 315–326
    • (2010) Epigenetics of Aging , pp. 315-326
    • Van Groen, T.1
  • 32
    • 33947317206 scopus 로고    scopus 로고
    • The epigenetic regulation of mammalian telomeres
    • Blasco MA: The epigenetic regulation of mammalian telomeres. Nat Rev Genet 2007; 8:299–309
    • (2007) Nat Rev Genet , vol.8 , pp. 299-309
    • Blasco, M.A.1
  • 33
    • 0028909019 scopus 로고
    • DNA damage and repair in telomeres: Relation to aging
    • Kruk PA, Rampino NJ, Bohr VA: DNA damage and repair in telomeres: relation to aging. Proc Natl Acad Sci USA 1995; 92:258–262
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 258-262
    • Kruk, P.A.1    Rampino, N.J.2    Bohr, V.A.3
  • 34
    • 84860510280 scopus 로고    scopus 로고
    • Disease-specific phenotypes in dopamine neurons from human iPSbased models of genetic and sporadic Parkinson’s disease
    • Sánchez-Danés A, Richaud-Patin Y, Carballo-Carbajal I, et al: Disease-specific phenotypes in dopamine neurons from human iPSbased models of genetic and sporadic Parkinson’s disease. EMBOMol Med 2012; 4:380–395
    • (2012) Embomol Med , vol.4 , pp. 380-395
    • Sánchez-Danés, A.1    Richaud-Patin, Y.2    Carballo-Carbajal, I.3
  • 35
    • 78650990326 scopus 로고    scopus 로고
    • Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice
    • Jaskelioff M, Muller FL, Paik J-H, et al: Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature 2011; 469:102–106
    • (2011) Nature , vol.469 , pp. 102-106
    • Jaskelioff, M.1    Muller, F.L.2    Paik, J.-H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.