UPLC-Q-TOF/MS-based screening and identification of the main flavonoids and their metabolites in rat bile, urine and feces after oral administration of Scutellaria baicalensis extract

Journal of Ethnopharmacology

Volumn 169, Issue , 2015, Pages 156-162

  Du, Le Yue ^a   Qian, Da Wei ^a   Shang, Er Xin ^a   Liu, Pei ^a   Jiang, Shu ^a   Guo, Jian Ming ^a   Su, Shu Lan ^a   Duan, Jin Ao ^a   Xu, Jun ^a   Zhao, Min ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Flavonoids; Metabolites; Scutellaria baicalensis extract; UPLC Q TOF MS

Indexed keywords

BAICALEIN; BAICALIN; DRUG METABOLITE; FLAVONOID; GLUCURONIDE; SCUTELLARIA BAICALENSIS EXTRACT; SULFATE; UNCLASSIFIED DRUG; WOGONIN; WOGONOSIDE; HERBACEOUS AGENT; PLANT EXTRACT;

ACETYLATION; ANIMAL EXPERIMENT; ARTICLE; BILE; CHINESE MEDICINE; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG EXCRETION; DRUG IDENTIFICATION; DRUG METABOLISM; DRUG SCREENING; FECES; HYDROXYLATION; IN VIVO STUDY; MALE; METHYLATION; NONHUMAN; PHARMACOLOGY; QUADRUPOLE MASS SPECTROMETRY; RAT; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINE; ANIMAL; CHEMISTRY; LIQUID CHROMATOGRAPHY; METABOLISM; ORAL DRUG ADMINISTRATION; PLANT ROOT; PROCEDURES; SPRAGUE DAWLEY RAT; TANDEM MASS SPECTROMETRY;

LAMIACEAE; RATTUS; SCUTELLARIA BAICALENSIS;

ADMINISTRATION, ORAL; ANIMALS; BILE; CHROMATOGRAPHY, LIQUID; DRUGS, CHINESE HERBAL; FECES; MALE; PLANT EXTRACTS; PLANT ROOTS; RATS; RATS, SPRAGUE-DAWLEY; TANDEM MASS SPECTROMETRY; URINE;

EID: 84929657485     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.04.039     Document Type: Article

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