Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography-tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese medicinal preparations containing scutellaria-coptis herb couple

Journal of Pharmaceutical and Biomedical Analysis

Volumn 53, Issue 3, 2010, Pages 591-598

  Feng, Jin ^a   Xu, Wen ^a   Tao, Xia ^a   Wei, Hua ^a   Cai, Fei ^a   Jiang, Bo ^a   Chen, Wansheng ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Determination; LC MS MS; Pharmacokinetics; Rat plasma; Scutellaria coptis herb couple

Indexed keywords

ACETONITRILE; BAICALEIN; BAICALIN; BERBERINE; FORMIC ACID; GEGEN QINLIAN; HERBACEOUS AGENT; JATRORRHIZINE; PALMATINE; PROTEIN; UNCLASSIFIED DRUG; WOGONIN; YIQING;

ANIMAL EXPERIMENT; ARTICLE; CAPSULE ENDOSCOPE; CHINESE MEDICINE; COPTIS; DRUG BLOOD LEVEL; DRUG DETERMINATION; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; RAT; SCUTELLARIA; TABLET; TANDEM MASS SPECTROMETRY;

ADMINISTRATION, ORAL; ANIMALS; BERBERINE; BERBERINE ALKALOIDS; CHROMATOGRAPHY, LIQUID; COPTIS; FLAVANONES; FLAVONOIDS; MALE; MEDICINE, CHINESE TRADITIONAL; RATS; RATS, SPRAGUE-DAWLEY; SCUTELLARIA; TANDEM MASS SPECTROMETRY;

EID: 77954861154     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2010.04.002     Document Type: Article

References (19)

1. Lin C.L., Hsu H.Y. Herb Couples 1992, Oriental Healing Arts Institute, Los Angeles, CA, pp. 1-13, 25.
2. Chinese Pharmacopoeia Commission The Pharmacopoeia of the People's Republic of China 2005, vol. 1. Chemical Industry Press, Beijing.
3. Ye F., Wang H., Jiang S., Wu J., Shao J., Cheng X., Tu Y., Zhang D.Y. Quality evaluation of commercial extracts of Scutellaria baicalensis. Nutr. Cancer 2004, 49:217-222.
4. Kuo C.L., Chi C.W., Liu T.Y. The anti-inflammatory potential of berberine in vitro and in vivo. Cancer Lett. 2004, 203:127-137.
5. Schmeller T., Latz-Bruning B., Wink M. Biochemical activities of berberine, palmatine and sanguinarine mediating chemical defence against microorganisms and herbivores. Phytochemistry 1997, 44:257-266.
6. Wang Y., Yao Y., An R., You L., Wang X.H. Simultaneous determination of puerarin, daidzein, baicalin, wogonoside and liquiritin of GegenQinlian decoction in rat plasma by ultra-performance liquid chromatography-mass spectrometry. J. Chromatogr. B 2009, 877:1820-1826.
7. Kotani A., Kojima S., Hakamata H., Kusu F. HPLC with electrochemical detection to examine the pharmacokinetics of baicalin and baicalein in rat plasma after oral administration of a Kampo medicine. Anal. Biochem. 2006, 350:99-104.
8. Kim Y.H., Jeong D.W., Paek I.B., Ji H.Y., Kim Y.C., Sohn D.H., Lee H.S. Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma. J. Chromatogr. B 2006, 844:261-267.
9. Chuang W.C., Young D.S., Liu L.K., Sheu S.J. Liquid chromatographic-electrospray mass spectrometric analysis of Coptidis Rhizoma. J. Chromatogr. A 1996, 755:19-26.
10. Lu T., Liang Y., Song J., Xie L., Wang G.J., Liu X.D. Simultaneous determination of berberine and palmatine in rat plasma by HPLC-ESI-MS after oral administration of traditional Chinese medicinal preparation Huang-Lian-Jie-Du decoction and the pharmacokinetic application of the method. J. Pharm. Biomed. Anal. 2006, 40:1218-1224.
11. Yu S., Pang X.Y., Deng Y.X., Liu L., Liang Y., Xie L., Wang G.J., Wang X.T. A sensitive and specific liquid chromatography mass spectrometry method for simultaneous determination of berberine, palmatine, coptisine, epiberberine and jatrorrhizine from Coptidis Rhizoma in rat plasma. Int. J. Mass Spectrom. 2007, 268:30-37.
12. Deng Y., Liao Q.F., Li S.H., Bi K.S., Pan B.Y., Xie Z.Y. Simultaneous determination of berberine, palmatine and jatrorrhizine by liquid chromatography-tandem mass spectrometry in rat plasma and its application in a pharmacokinetic study after oral administration of coptis-evodia herb couple. J. Chromatogr. B 2008, 863:195-205.
13. Huang J.M., Wang G.Q., Jin Y.E., Shen T., Weng W.Y. Determination of palmatine in canine plasma by liquid chromatography-tandem mass spectrometry with solid-phase extraction. J. Chromatogr. B 2007, 854:279-285.
14. Hua W.Y., Ding L., Chen Y., Gong B., He J.C., Xu G.L. Determination of berberine in human plasma by liquid chromatography-electrospray ionization-mass spectrometry. J. Pharm. Biomed. Anal. 2007, 44:931-937.
15. Gupta P.K., Hubbard M., Gurley B., Hendrickson H.P. Validation of a liquid chromatography-tandem mass spectrometric assay for the quantitative determination of hydrastine and berberine in human serum. J. Pharm. Biomed. Anal. 2009, 49:1021-1026.
16. Li Y., Gao J.P., Xu X., Dai L.X. Simultaneous determination of baicalin, rhein and berberine in rat plasma by column-switching high-performance liquid chromatography. J. Chromatogr. B 2006, 838:50-55.
17. US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Guidance for Industry, Bioanalytical Method Validation, May 2001.
18. Zhou S., Gao Y., Jiang W., Huang M., Xu A., Paxton J.W. Interactions of herbs with cytochrome P450. Drug Metab. Rev. 2003, 35:35-98.
19. Zhou S., Koh H.L., Gao Y., Gong Z.Y., Lee E.J.D. Herbal bioactivation: the good, the bad and the ugly. Life Sci. 2004, 74:935-968.