Comparison of the selective targeting efficacy of Salmonella typhimurium A1-R and VNP20009 on the lewis lung carcinoma in nude mice

Oncotarget

Volumn 6, Issue 16, 2015, Pages 14625-14631

  Zhang, Yong ^a   Zhang, Nan ^a   Zhao, Ming ^a   Hoffman, Robert M ^a,b  

^a ANTICANCER INC   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Gfp; Lung cancer; Rfp; Salmonella typhimurium A1 R; Vnp20009

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; BACTERIAL VACCINE; VNP 20009;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; AUXOTROPHIC MUTANT; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CANCER INHIBITION; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DRUG TOLERABILITY; FEMALE; LEWIS CARCINOMA; LIVER; MOUSE; NONHUMAN; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SPLEEN; TUMOR VOLUME; WEIGHT REDUCTION; ANIMAL; CARCINOMA, LEWIS LUNG; DISEASE MODEL; DRUG EFFECTS; DRUG SCREENING; HUMAN; LUNG NEOPLASMS; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; BACTERIAL VACCINES; CARCINOMA, LEWIS LUNG; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; HUMANS; LUNG NEOPLASMS; MICE; MICE, NUDE; SALMONELLA TYPHIMURIUM; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84929631636     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3342     Document Type: Article

References (38)

1. William Coley. Available at: http://en.wikipedia.org/wiki/William_Coley [last accessed 12 December 2013].
2. Hoffman RM. The preclinical discovery of bacterial therapy for the treatment of metastatic cancer with unique advantages. Expert Opin Drug Discov 2012; 7:73-83.
3. Forbes NS. Engineering the perfect (bacterial) cancer therapy. Nat Rev Cancer 2010; 10:785-94.
4. Hoffman RM. Bugging Tumors. Cancer Discovery 2012; 2: 588-590.
5. Yazawa K, Fujimori M, Nakamura T, Sasaki T, Amano J, Kano Y, Taniguchi S. Bifidobacterium longum as a delivery system for gene therapy of chemically induced rat mammary tumors. Breast Cancer Res Treat 2001;66:165-70
6. Dang LH, Bettegowda C, Huso DL, Kinzler KW, Vogelstein B. Combination bacteriolytic therapy for the treatment of experimental tumors. Proc Natl Acad Sci USA 2001;98: 15155-60.
7. Roberts NJ, Zhang L, Janku F, Collins A, Bai RY, Staedtke V, Rusk AW, Tung D, Miller M, Roix J, Khanna KV, Murthy R, Benjamin RS, Helgason T, Szvalb AD, Bird JE, Roy-Chowdhuri S, Zhang HH, Qiao Y, Karim B, McDaniel J, Elpiner A, Sahora A, Lachowicz J, Phillips B, Turner A, Klein MK, Post G, Diaz LA Jr, Riggins GJ, Papadopoulos N, Kinzler KW, Vogelstein B, Bettegowda C, Huso DL, Varterasian M, Saha S, Zhou S. Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses. Sci Transl Med 2014; 6:249ra111.
8. Pawelek JM, Low KB, Bermudes D. Bacteria as tumourtargeting vectors. Lancet Oncol 2003;4:548-556.
9. Pawelek JM, Low KB, Bermudes D. Tumor-targeted Salmonella as a novel anticancer vector. Cancer Res 1997; 57:4537-4544.
10. Toso JF, Gill VJ, Hwu P, Marincola FM, Restifo NP, Schwartzentruber DJ, Sherry RM, Topalian SL, Yang JC, Stock F, Freezer LJ, Morton KE, Seipp C, Haworth L, Mavroukakis S, White D, MacDonald S, Mao J, Sznol M, Rosenberg SA. Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma. J Clin Oncol 2002; 20:142-52.
11. Zhao M, Yang M, Li X-M, Jiang P, Baranov E, Li S, Xu, M., Penman, S, Hoffman RM. Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium. Proc Natl Acad Sci USA 2005; 102:755-760.
12. Zhao M, Yang M, Ma H, Li X, Tan X, Li S, Yang Z, Hoffman RM. Targeted therapy with a Salmonella typhimurium leucine-arginine auxotroph cures orthotopic human breast tumors in nude mice. Cancer Res 2006; 66:7647-7652.
13. Zhao M, Geller J, Ma H, Yang M, Penman S, Hoffman RM. Monotherapy with a tumor-targeting mutant of Salmonella typhimurium cures orthotopic metastatic mouse models of human prostate cancer. Proc Natl Acad Sci USA 2007; 104:10170-10174.
14. Nagakura C, Hayashi K, Zhao M, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Bouvet M, Hoffman RM. Efficacy of a genetically-modifi ed Salmonella typhimurium in an orthotopic human pancreatic cancer in nude mice. Anticancer Res 2009; 29:1873-1878.
15. Hayashi K, Zhao M, Yamauchi K, Yamamoto N, Tsuchiya H, Tomita K, Kishimoto H, Bouvet M, Hoffman RM. Systemic targeting of primary bone tumor and lung metastasis of high-grade osteosarcoma in nude mice with a tumor-selective strain of Salmonella typhimurium. Cell Cycle 2009; 8:870-875.
16. Yam C, Zhao M, Hayashi K, Ma H, Kishimoto H, McElroy M, Bouvet M, Hoffman RM. Monotherapy with a tumortargeting mutant of S. typhimurium inhibits liver metastasis in a mouse model of pancreatic cancer. J Surg Res 2010; 164:248-255.
17. Kimura H, Zhang L, Zhao M, Hayashi K, Tsuchiya H, Tomita K, Bouvet M, Wessels J, Hoffman RM. Targeted therapy of spinal cord glioma with a genetically-modified Salmonella typhimurium. Cell Prolif 2010; 43:41-48.
18. Matsumoto Y, Miwa S, Zhang Y, Hiroshima Y, Yano S, Uehara F, Yamamoto M, Toneri M, Bouvet M, Matsubara H, Hoffman RM, Zhao M. Efficacy of tumor-targeting Salmonella typhimurium A1-R on nude mouse models of metastatic and disseminated human ovarian cancer. J Cell Biochem 2014; 115: 1996-2003.
19. Montiyama M, Zhao M, l{jmura H, Tran B, Chishima T, Bouvet M, Endo I, Hoffman RM. Inhibition and eradication of human glioma with tumor-targeting Salmonella typhimurium in an orthotopic nude-mouse model. Cell Cycle 2012; 11: 628-632.
20. Zhang Y, Miwa S, Zhang N, Hoffman RM, Zhao M. Tumor-targeting Salmonella typhimurium A1-R arrests growth of breast-cancer brain metastasis. Oncotarget, in press.
21. Miwa S, Yano S, Zhang Y, Matsumoto Y, Uehara F, Yamamoto M, Hiroshima Y, Kimura H, Hayashi K, Yamamoto N, Bouvet M, Tsuchiya H, Hoffman RM, Zhao M. Tumor-targeting Salmonella typhimurium A1-R prevents experimental human breast cancer bone metastasis in nude mice. Oncotarget 2014; 5: 7119-7125.
22. Liu F, Zhang L, Hoffman RM, Zhao M. Vessel destruction by tumor targeting Salmonella typhimurium A1-R is enhanced by high tumor vascularity. Cell Cycle 2010; 9:4518-4524.
23. Yano S, Zhang Y, Zhao M, Hiroshima Y, Miwa S, Uehara F, Kishimoto H, Tazawa H, Bouvet M, Fujiwara T, Hoffman RM. Tumor-targeting Salmonella typhimurium A1-R decoys quiescent cancer cells to cycle as visualized by FUCCI imaging and become sensitive to chemotherapy. Cell Cycle 2014; 13: 3958-3963.
24. Blagosklonny MV. How cancer could be cured by 2015. Cell Cycle 2005; 4:269-278.
25. Blagosklonny MV. Tissue-selective therapy of cancer. Br J Cancer 2003; 89:1147-1151.
26. Blagosklonny MV. Matching targets for selective cancer therapy. Drug Discov Today 2003; 8:1104-1107.
27. Blagosklonny MV. "Targeting the absence" and therapeutic engineering for cancer therapy. Cell Cycle 2008; 7:1307-1312.
28. Blagosklonny MV. Teratogens as anti-cancer drugs. Cell Cycle 2005; 4:1518-1521.
29. Blagosklonny MV. Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells. Leukemia 2001; 15:936-941.
30. Blagosklonny MV. Target for cancer therapy: proliferating cells or stem cells. Leukemia 2006; 20:385-391.
31. Blagosklonny MV. Cancer stem cell and cancer stemloids: from biology to therapy. Cancer Biol Ther 2007; 6:1684-1690.
32. Hoffman RM, Yang M. Subcellular imaging in the live mouse. Nat Protoc 2006; 1:775-82.
33. Hoffman RM, Yang M. Color-coded fluorescence imaging of tumor-host interactions. Nat Protoc 2006; 1:928-35.
34. Hoffman RM, Yang M. Whole-body imaging with fluorescent proteins. Nat Protoc 2006; 1:1429-1438.
35. Zhao M, Suetsugu A, Ma H, Zhang L, Liu F, Zhang Y, Tran B, Hoffman RM. Efficacy against lung metastasis with a tumor-targeting mutant of Salmonella typhimurium in immunocompetent mice. Cell Cycle 2012; 11: 187-193.
36. Mansfield JR, Gossage KW, Hoyt CC and Levenson RM. Autofluorescence removal, multiplexing, and automated analysis methods for in vivo fluorescence imaging. J Biomed Opt 2005; 10: 41207.
37. Levenson RM and Mansfield JR. Multispectral in biology and medicine: Slices of life. Cytometry A 2006; 69:748-758.
38. Zhang Y, Hiroshima Y, Ma H, Zhang N, Hoffman RM, Zhao M. Complementarity of variable-magnification and spectral-separation fluorescence imaging systems for noninvasive detection of metastasis and intravital detection of single cancer cells in mouse models. Anticancer Research, 2015; 35: 661-668.