-
1
-
-
0025946095
-
Salmeterol, a novel, long-acting beta 2-adrenoceptor agonist: Characterization of pharmacological activity in vitro and in vivo
-
Ball, D.I., Brittain, R.T., Coleman, R.A., Denyer, L.H., Jack, D., Johnson, M., Lunts, L.H., Nials, A.T., Sheldrick, K.E., and Skidmore, I.F. (1991). Salmeterol, a novel, long-acting beta 2-adrenoceptor agonist: characterization of pharmacological activity in vitro and in vivo. Br. J. Pharmacol. 104, 665-671.
-
(1991)
Br. J. Pharmacol
, vol.104
, pp. 665-671
-
-
Ball, D.I.1
Brittain, R.T.2
Coleman, R.A.3
Denyer, L.H.4
Jack, D.5
Johnson, M.6
Lunts, L.H.7
Nials, A.T.8
Sheldrick, K.E.9
Skidmore, I.F.10
-
2
-
-
0020597547
-
Dose-response curves to inhaled beta-adrenoceptor agonists in normal and asthmatic subjects
-
Barnes, P.J., and Pride, N.B. (1983). Dose-response curves to inhaled beta-adrenoceptor agonists in normal and asthmatic subjects. Br. J. Clin. Pharmacol. 15, 677-682.
-
(1983)
Br. J. Clin. Pharmacol
, vol.15
, pp. 677-682
-
-
Barnes, P.J.1
Pride, N.B.2
-
3
-
-
18744412122
-
Validation of IKK beta as therapeutic target in airway inflammatory disease by adenoviral-mediated delivery of dominant-negative IKK beta to pulmonary epithelial cells
-
Catley, M.C., Chivers, J.E., Holden, N.S., Ba rnes, P.J., and Newton, R. (2005). Validation of IKK beta as therapeutic target in airway inflammatory disease by adenoviral-mediated delivery of dominant-negative IKK beta to pulmonary epithelial cells. Br. J. Pharmacol. 145, 114-122.
-
(2005)
Br. J. Pharmacol
, vol.145
, pp. 114-122
-
-
Catley, M.C.1
Chivers, J.E.2
Holden, N.S.3
Ba Rnes, P.J.4
Newton, R.5
-
4
-
-
56149100905
-
Role of matrix metalloprotease-9 in hyperoxic injury in developing lung
-
Chetty, A., Cao, G.J., Severgnini, M., Simon, A., Warburton, R., and Nielsen, H.C. (2008). Role of matrix metalloprotease-9 in hyperoxic injury in developing lung. Am. J. Physiol. Lung Cell. Mol. Physiol. 295, L584-592.
-
(2008)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.295
, pp. L584-L592
-
-
Chetty, A.1
Cao, G.J.2
Severgnini, M.3
Simon, A.4
Warburton, R.5
Nielsen, H.C.6
-
5
-
-
4444322565
-
Tumor necrosis factor-alpha drives 70% of cigarette smoke-induced emphysema in the mouse
-
Churg, A., Wang, R.D., Tai, H., Wang, X., Xie, C., and Wright, J.L. (2004). Tumor necrosis factor-alpha drives 70% of cigarette smoke-induced emphysema in the mouse. Am. J. Respir. Crit. Care Med. 170, 492-498.
-
(2004)
Am. J. Respir. Crit. Care Med
, vol.170
, pp. 492-498
-
-
Churg, A.1
Wang, R.D.2
Tai, H.3
Wang, X.4
Xie, C.5
Wright, J.L.6
-
6
-
-
34547815598
-
Effect of an MMP-9/MMP-12 inhibitor on smokeinduced emphysema and airway remodelling in guinea pigs
-
Churg, A., Wang, R., Wang, X., Onnervik, P.O., Thim, K., and Wright, J.L. (2007). Effect of an MMP-9/MMP-12 inhibitor on smokeinduced emphysema and airway remodelling in guinea pigs. Thorax 62, 706-713.
-
(2007)
Thorax
, vol.62
, pp. 706-713
-
-
Churg, A.1
Wang, R.2
Wang, X.3
Onnervik, P.O.4
Thim, K.5
Wright, J.L.6
-
7
-
-
0014439018
-
Salbutamol: A new, selective beta-adrenoceptive receptor stimulant
-
Cullum, V.A., Farmer, J.B., Jack, D., and Levy, G.P. (1969). Salbutamol: a new, selective beta-adrenoceptive receptor stimulant. Br. J. Pharmacol. 35, 141-151.
-
(1969)
Br. J. Pharmacol
, vol.35
, pp. 141-151
-
-
Cullum, V.A.1
Farmer, J.B.2
Jack, D.3
Levy, G.P.4
-
8
-
-
77954800883
-
Once-daily bronchodilators for chronic obstructive pulmonary disease: Indacaterol versus tiotropium
-
Donohue, J.F., Fogarty, C., Lotvall, J., Mahler, D.A., Worth, H., Yorgancioglu, A., Iqbal, A., Swales, J., Owen, R., Higgins, M., et al. (2010). Once-daily bronchodilators for chronic obstructive pulmonary disease: indacaterol versus tiotropium. Am. J. Respir. Crit. Care Med. 182, 155-162.
-
(2010)
Am. J. Respir. Crit. Care Med
, vol.182
, pp. 155-162
-
-
Donohue, J.F.1
Fogarty, C.2
Lotvall, J.3
Mahler, D.A.4
Worth, H.5
Yorgancioglu, A.6
Iqbal, A.7
Swales, J.8
Owen, R.9
Higgins, M.10
-
9
-
-
57749105255
-
Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease
-
Edwards, M.R., Bartlett, N.W., Clarke, D., Birrell, M., Belvisi, M., and Johnston, S.L. (2009). Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease. Pharmacol. Ther. 121, 1-13.
-
(2009)
Pharmacol. Ther
, vol.121
, pp. 1-13
-
-
Edwards, M.R.1
Bartlett, N.W.2
Clarke, D.3
Birrell, M.4
Belvisi, M.5
Johnston, S.L.6
-
10
-
-
0030811545
-
Elevated levels of matrix metalloproteinases in bronchoalveolar lavage fluid of emphysematous patients
-
Finlay, G.A., Russell, K.J., McMahon, K.J., D’Arcy E M., Masterson, J.B., FitzGerald, M.X., and O’Connor, C.M. (1997). Elevated levels of matrix metalloproteinases in bronchoalveolar lavage fluid of emphysematous patients. Thorax 52, 502-506.
-
(1997)
Thorax
, vol.52
, pp. 502-506
-
-
Finlay, G.A.1
Russell, K.J.2
McMahon, K.J.3
D’Arcy, E.M.4
Masterson, J.B.5
Fitzgerald, M.X.6
O’Connor, C.M.7
-
11
-
-
2342510314
-
Identification of beta-arrestin2 as a G protein-coupled receptor stimulated regulator of NF-kappaB pathways
-
Gao, H., Sun, Y., Wu, Y., Luan, B., Wang, Y., Qu, B., and Pei, G. (2004). Identification of beta-arrestin2 as a G protein-coupled receptor stimulated regulator of NF-kappaB pathways. Mol. Cell 14, 303-317.
-
(2004)
Mol. Cell
, vol.14
, pp. 303-317
-
-
Gao, H.1
Sun, Y.2
Wu, Y.3
Luan, B.4
Wang, Y.5
Qu, B.6
Pei, G.7
-
12
-
-
0031897632
-
NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
-
Ghosh, S., May, M.J., and Kopp, E.B. (1998). NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Ann. Rev. Immunol. 16, 225-260.
-
(1998)
Ann. Rev. Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
13
-
-
0028889036
-
Adverse effects of inhaled corticosteroids
-
Hanania, N.A., Chapman, K.R., and Kesten, S. (1995). Adverse effects of inhaled corticosteroids. Am. J. Med. 98, 196-208.
-
(1995)
Am. J. Med
, vol.98
, pp. 196-208
-
-
Hanania, N.A.1
Chapman, K.R.2
Kesten, S.3
-
14
-
-
29544449036
-
Molecular mechanisms of beta(2)-adrenergic receptor function, response, and regulation
-
quiz 25
-
Johnson, M. (2006) Molecular mechanisms of beta(2)-adrenergic receptor function, response, and regulation. J. Allergy Clin. Immunol. 117, 18-24; quiz 25.
-
(2006)
J. Allergy Clin. Immunol
, vol.117
, pp. 18-24
-
-
Johnson, M.1
-
15
-
-
2442462505
-
The possible role of matrix metalloproteinase (MMP)-2 and MMP-9 in cancer, e.g. acute leukemia
-
Klein, G., Vellenga, E., Fraaije, M.W., Kamps, W.A., and de Bont, E.S. (2004). The possible role of matrix metalloproteinase (MMP)-2 and MMP-9 in cancer, e.g. acute leukemia. Crit. Rev. Oncol. Hematol. 50, 87-100.
-
(2004)
Crit. Rev. Oncol. Hematol
, vol.50
, pp. 87-100
-
-
Klein, G.1
Vellenga, E.2
Fraaije, M.W.3
Kamps, W.A.4
De Bont, E.S.5
-
16
-
-
77951722077
-
Physcion-8-O-beta-D-glucopyranoside enhances the commitment of mouse mesenchymal progenitors into osteoblasts and their differentiation: Possible involvement of signaling pathways to activate BMP gene expression
-
Lee, S.U., Choi, Y.H., Kim, Y.S., Park, S.J., Kwak, H.B., Min, Y.K., Kim, H.N., Lim, K.E., Choi, J.Y., Rhee, M., et al. (2010). Physcion-8-O-beta-D-glucopyranoside enhances the commitment of mouse mesenchymal progenitors into osteoblasts and their differentiation: Possible involvement of signaling pathways to activate BMP gene expression. J. Cell. Biochem. 109, 1148-1157.
-
(2010)
J. Cell. Biochem
, vol.109
, pp. 1148-1157
-
-
Lee, S.U.1
Choi, Y.H.2
Kim, Y.S.3
Park, S.J.4
Kwak, H.B.5
Min, Y.K.6
Kim, H.N.7
Lim, K.E.8
Choi, J.Y.9
Rhee, M.10
-
17
-
-
84888625872
-
Beta-Arrestin 2 mediates G protein-coupled receptor 43 signals to nuclear Factor-kappaB
-
Lee, S.U., In, H.J., Kwon, M.S., Park, B.O., Jo, M., Kim, M.O., Cho, S., Lee, S., Lee, H.J., Kwak, Y.S., et al. (2013). beta-Arrestin 2 mediates G protein-coupled receptor 43 signals to nuclear Factor-kappaB. Biol. Pharm. Bull. 36, 1754-1759.
-
(2013)
Biol. Pharm. Bull
, vol.36
, pp. 1754-1759
-
-
Lee, S.U.1
In, H.J.2
Kwon, M.S.3
Park, B.O.4
Jo, M.5
Kim, M.O.6
Cho, S.7
Lee, S.8
Lee, H.J.9
Kwak, Y.S.10
-
18
-
-
17644402459
-
Transduction of receptor signals by beta-arrestins
-
Lefkowitz, R.J., and Shenoy, S.K. (2005). Transduction of receptor signals by beta-arrestins. Science 308, 512-517.
-
(2005)
Science
, vol.308
, pp. 512-517
-
-
Lefkowitz, R.J.1
Shenoy, S.K.2
-
19
-
-
79958723466
-
Pachymic acid impairs breast cancer cell invasion by suppressing nuclear factorkappaB-dependent matrix metalloproteinase-9 expression
-
Ling, H., Zhang, Y., Ng, K.Y., and Chew, E.H. (2011). Pachymic acid impairs breast cancer cell invasion by suppressing nuclear factorkappaB-dependent matrix metalloproteinase-9 expression. Breast Cancer Res. Treat. 126, 609-620.
-
(2011)
Breast Cancer Res. Treat
, vol.126
, pp. 609-620
-
-
Ling, H.1
Zhang, Y.2
Ng, K.Y.3
Chew, E.H.4
-
20
-
-
33646493793
-
Prevalence of COPD in women compared to men around the time of diagnosis of primary lung cancer
-
Loganathan, R.S., Stover, D.E., Shi, W., and Venkatraman, E. (2006). Prevalence of COPD in women compared to men around the time of diagnosis of primary lung cancer. Chest 129, 1305-1312.
-
(2006)
Chest
, vol.129
, pp. 1305-1312
-
-
Loganathan, R.S.1
Stover, D.E.2
Shi, W.3
Venkatraman, E.4
-
21
-
-
27744548897
-
Tumor necrosis factor-alpha triggers mucus production in airway epithelium through an IkappaB kinase betadependent mechanism
-
Lora, J.M., Zhang, D.M., Liao, S.M., Burwell, T., King, A.M., Barker, P.A., Singh, L., Keaveney, M., Morgenstern, J., Gutierrez-Ramos, J.C., et al. (2005). Tumor necrosis factor-alpha triggers mucus production in airway epithelium through an IkappaB kinase betadependent mechanism. J. Biol. Chem. 280, 36510-36517.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 36510-36517
-
-
Lora, J.M.1
Zhang, D.M.2
Liao, S.M.3
Burwell, T.4
King, A.M.5
Barker, P.A.6
Singh, L.7
Keaveney, M.8
Morgenstern, J.9
Gutierrez-Ramos, J.C.10
-
22
-
-
29244452161
-
Betaarrestin2 functions as a phosphorylation-regulated suppressor of UV-induced NF-kappaB activation
-
Luan, B., Zhang, Z., Wu, Y., Kang, J., and Pei, G. (2005). Betaarrestin2 functions as a phosphorylation-regulated suppressor of UV-induced NF-kappaB activation. EMBO J. 24, 4237-4246.
-
(2005)
EMBO J
, vol.24
, pp. 4237-4246
-
-
Luan, B.1
Zhang, Z.2
Wu, Y.3
Kang, J.4
Pei, G.5
-
23
-
-
20444415267
-
Tumor necrosis factor-alpha overexpression in lung disease: A single cause behind a complex phenotype
-
Lundblad, L.K., Thompson-Figueroa, J., Leclair, T., Sullivan, M.J., Poynter, M.E., Irvin, C.G., and Bates, J.H. (2005). Tumor necrosis factor-alpha overexpression in lung disease: a single cause behind a complex phenotype. Am. J. Respir. Crit. Care Med. 171, 1363-1370.
-
(2005)
Am. J. Respir. Crit. Care Med
, vol.171
, pp. 1363-1370
-
-
Lundblad, L.K.1
Thompson-Figueroa, J.2
Leclair, T.3
Sullivan, M.J.4
Poynter, M.E.5
Irvin, C.G.6
Bates, J.H.7
-
24
-
-
0036473397
-
The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals
-
Luttrell, L.M., and Lefkowitz, R.J. (2002). The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J. Cell Sci. 115, 455-465.
-
(2002)
J. Cell Sci
, vol.115
, pp. 455-465
-
-
Luttrell, L.M.1
Lefkowitz, R.J.2
-
25
-
-
75749095929
-
TNF-alpha inhibitors in asthma and COPD: We must not throw the baby out with the bath water. Pulm. Pharmacol
-
Matera, M.G., Calzetta, L., and Cazzola, M. (2010). TNF-alpha inhibitors in asthma and COPD: we must not throw the baby out with the bath water. Pulm. Pharmacol. Ther. 23, 121-128.
-
(2010)
Ther
, vol.23
, pp. 121-128
-
-
Matera, M.G.1
Calzetta, L.2
Cazzola, M.3
-
26
-
-
39449111918
-
Matrix metalloproteinase-9/gelatinase B is a putative therapeutic target of chronic obstructive pulmonary disease and multiple sclerosis
-
Muroski, M.E., Roycik, M.D., Newcomer, R.G., Van den Steen, P.E., Opdenakker, G., Monroe, H.R., Sahab, Z.J., and Sang, Q.X. (2008). Matrix metalloproteinase-9/gelatinase B is a putative therapeutic target of chronic obstructive pulmonary disease and multiple sclerosis. Curr. Pharm. Biotechnol. 9, 34-46.
-
(2008)
Curr. Pharm. Biotechnol
, vol.9
, pp. 34-46
-
-
Muroski, M.E.1
Roycik, M.D.2
Newcomer, R.G.3
Van Den Steen, P.E.4
Opdenakker, G.5
Monroe, H.R.6
Sahab, Z.J.7
Sang, Q.X.8
-
27
-
-
33847724812
-
Effect of indacaterol, a novel long-acting beta2-agonist, on isolated human bronchi
-
Naline, E., Trifilieff, A., Fairhurst, R.A., Advenier, C., and Molimard, M. (2007). Effect of indacaterol, a novel long-acting beta2-agonist, on isolated human bronchi. Eur. Respir. J. 29, 575-581.
-
(2007)
Eur. Respir. J
, vol.29
, pp. 575-581
-
-
Naline, E.1
Trifilieff, A.2
Fairhurst, R.A.3
Advenier, C.4
Molimard, M.5
-
28
-
-
77956165390
-
GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects
-
Oh, D.Y., Talukdar, S., Bae, E.J., Imamura, T., Morinaga, H., Fan, W., Li, P., Lu, W.J., Watkins, S.M., and Olefsky, J.M. (2010). GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell 142, 687-698.
-
(2010)
Cell
, vol.142
, pp. 687-698
-
-
Oh, D.Y.1
Talukdar, S.2
Bae, E.J.3
Imamura, T.4
Morinaga, H.5
Fan, W.6
Li, P.7
Lu, W.J.8
Watkins, S.M.9
Olefsky, J.M.10
-
29
-
-
84860476284
-
Early detection of COPD is important for lung cancer surveillance
-
Sekine, Y., Katsura, H., Koh, E., Hiroshima, K., and Fujisawa, T. (2012). Early detection of COPD is important for lung cancer surveillance. Eur. Respir. J. 39, 1230-1240.
-
(2012)
Eur. Respir. J
, vol.39
, pp. 1230-1240
-
-
Sekine, Y.1
Katsura, H.2
Koh, E.3
Hiroshima, K.4
Fujisawa, T.5
-
30
-
-
0242721361
-
Multifaceted roles of betaarrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling
-
Shenoy, S.K., and Lefkowitz, R.J. (2003). Multifaceted roles of betaarrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling. Biochem. J. 375, 503-515.
-
(2003)
Biochem. J
, vol.375
, pp. 503-515
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
31
-
-
84877682284
-
Combination bronchodilator therapy in the management of chronic obstructive pulmonary disease
-
Tashkin, D.P., and Ferguson, G.T. (2013). Combination bronchodilator therapy in the management of chronic obstructive pulmonary disease. Respir. Res. 14, 49.
-
(2013)
Respir. Res
, vol.14
, pp. 49
-
-
Tashkin, D.P.1
Ferguson, G.T.2
-
32
-
-
8544242685
-
Effects of the long acting beta agonist formoterol on asthma control in asthmatic patients using inhaled corticosteroids. The Netherlands and Canadian formoterol study investigators
-
van der Molen, T., Postma, D.S., Turner, M.O., Jong, B.M., Malo, J.L., Chapman, K., Grossman, R., de Graaff, C.S., Riemersma, R.A., and Sears, M.R. (1997). Effects of the long acting beta agonist formoterol on asthma control in asthmatic patients using inhaled corticosteroids. The Netherlands and Canadian formoterol study investigators. Thorax 52, 535-539.
-
(1997)
Thorax
, vol.52
, pp. 535-539
-
-
Van Der Molen, T.1
Postma, D.S.2
Turner, M.O.3
Jong, B.M.4
Malo, J.L.5
Chapman, K.6
Grossman, R.7
De Graaff, C.S.8
Riemersma, R.A.9
Sears, M.R.10
-
33
-
-
0029947193
-
Association of chronic mucus hypersecretion with FEV1 decline and chronic obstructive pulmonary disease morbidity. Copenhagen City heart study group
-
Vestbo, J., Prescott, E., and Lange, P. (1996). Association of chronic mucus hypersecretion with FEV1 decline and chronic obstructive pulmonary disease morbidity. Copenhagen City heart study group. Am. J. Respir. Crit. Care Med. 153, 1530-1535.
-
(1996)
Am. J. Respir. Crit. Care Med
, vol.153
, pp. 1530-1535
-
-
Vestbo, J.1
Prescott, E.2
Lange, P.3
-
34
-
-
1542618313
-
Synergistic activation of NF-kappaB by nontypeable Haemophilus influenza and tumor necrosis factor alpha
-
Watanabe, T., Jono, H., Han, J., Lim, D.J., and Li, J.D. (2004). Synergistic activation of NF-kappaB by nontypeable Haemophilus influenza and tumor necrosis factor alpha. Proc. Natl. Acad. Sci. USA 101, 3563-3568.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3563-3568
-
-
Watanabe, T.1
Jono, H.2
Han, J.3
Lim, D.J.4
Li, J.D.5
-
35
-
-
67749104113
-
Optimising treatment for COPD--new strategies for combination therapy
-
Welte, T. (2009). Optimising treatment for COPD--new strategies for combination therapy. Int. J. Clin. Pract. 63, 1136-1149.
-
(2009)
Int. J. Clin. Pract
, vol.63
, pp. 1136-1149
-
-
Welte, T.1
-
36
-
-
2942554958
-
Beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha
-
Witherow, D.S., Garrison, T.R., Miller, W.E., and Lefkowitz, R.J. (2004). beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha. Proc. Natl. Acad. Sci. USA 101, 8603-8607.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 8603-8607
-
-
Witherow, D.S.1
Garrison, T.R.2
Miller, W.E.3
Lefkowitz, R.J.4
-
37
-
-
84859011075
-
Indacaterol in chronic obstructive pulmonary disease: An update for clinicians
-
Yorgancioglu, A. (2012). Indacaterol in chronic obstructive pulmonary disease: an update for clinicians. Ther. Adv. Chronic. Dis. 3, 25-36.
-
(2012)
Ther. Adv. Chronic. Dis
, vol.3
, pp. 25-36
-
-
Yorgancioglu, A.1
|