-
1
-
-
84855405497
-
The proliferation rate paradox in antimitotic chemotherapy
-
Mitchison, T. J. The proliferation rate paradox in antimitotic chemotherapy. Mol. Biol. Cell 23, 1-6, doi: Doi 10.1091/Mbc. E10-04-0335 (2012).
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 1-6
-
-
Mitchison, T.J.1
-
2
-
-
0034994444
-
Nucleoside analogues: Mechanisms of drug resistance and reversal strategies
-
Galmarini, C. M., Mackey, J. R. & Dumontet, C. Nucleoside analogues: mechanisms of drug resistance and reversal strategies. Leukemia 15, 875-890, doi: Doi 10.1038/Sj. Leu.2402114 (2001).
-
(2001)
Leukemia
, vol.15
, pp. 875-890
-
-
Galmarini, C.M.1
Mackey, J.R.2
Dumontet, C.3
-
3
-
-
79957815352
-
Cardiovascular complications of conventional and targeted adjuvant breast cancer therapy
-
Harbeck, N., Ewer, M. S., De Laurentiis, M., Suter, T. M. & Ewer, S. M. Cardiovascular complications of conventional and targeted adjuvant breast cancer therapy. Ann. Oncol. 22, 1250-1258, doi: Doi 10.1093/Annonc/Mdq543 (2011).
-
(2011)
Ann. Oncol.
, vol.22
, pp. 1250-1258
-
-
Harbeck, N.1
Ewer, M.S.2
De Laurentiis, M.3
Suter, T.M.4
Ewer, S.M.5
-
4
-
-
67649958842
-
Cardiovascular complications of cancer therapy incidence, pathogenesis, diagnosis, and management
-
Yeh, E. T. H. & Bickford, C. L. Cardiovascular Complications of Cancer Therapy Incidence, Pathogenesis, Diagnosis, and Management. J. Am. Coll. Cardiol. 53, 2231-2247, doi: Doi 10.1016/J. Jacc.2009.02.050 (2009).
-
(2009)
J. Am. Coll. Cardiol.
, vol.53
, pp. 2231-2247
-
-
Yeh, E.T.H.1
Bickford, C.L.2
-
5
-
-
6044274062
-
Cardiovascular complications of cancer therapy - Diagnosis, pathogenesis, and management
-
Yeh, E. T. H. et al. Cardiovascular complications of cancer therapy - Diagnosis, pathogenesis, and management. Circulation 109, 3122-3131, doi: Doi 10.1161/01. Cir.0000133187.74800. B9 (2004).
-
(2004)
Circulation
, vol.109
, pp. 3122-3131
-
-
Yeh, E.T.H.1
-
6
-
-
84859355565
-
Complexity in the signaling network: Insights from the use of targeted inhibitors in cancer therapy
-
Logue, J. S. & Morrison, D. K. Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy. Gene. Dev. 26, 641-650, doi: Doi 10.1101/Gad.186965.112 (2012).
-
(2012)
Gene. Dev.
, vol.26
, pp. 641-650
-
-
Logue, J.S.1
Morrison, D.K.2
-
7
-
-
10444261212
-
Development of TGF-beta signalling inhibitors for cancer therapy
-
Yingling, J. M., Blanchard, K. L. & Sawyer, J. S. Development of TGF-beta signalling inhibitors for cancer therapy. Nat. Rev. Drug Discov. 3, 1011-1022, doi: Doi 10.1038/Nrd1580 (2004).
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 1011-1022
-
-
Yingling, J.M.1
Blanchard, K.L.2
Sawyer, J.S.3
-
8
-
-
15644368237
-
Androgen receptor gene amplification: A possible molecular mechanism for androgen deprivation therapy failure in prostate cancer
-
Koivisto, P. et al. Androgen receptor gene amplification: A possible molecular mechanism for androgen deprivation therapy failure in prostate cancer. Cancer Res. 57, 314-319 (1997).
-
(1997)
Cancer Res.
, vol.57
, pp. 314-319
-
-
Koivisto, P.1
-
9
-
-
42449153652
-
Small molecule HER-2 tyrosine kinase inhibitors
-
Spector, N., Xia, W. L., El-Hariry, I., Yarden, Y. & Bacus, S. Small molecule HER-2 tyrosine kinase inhibitors. Breast Cancer Res. 9, doi: Artn 205 Doi 10.1186/Bcr1652 (2007).
-
(2007)
Breast Cancer Res.
, pp. 9
-
-
Spector, N.1
Xia, W.L.2
El-Hariry, I.3
Yarden, Y.4
Bacus, S.5
-
10
-
-
37049183697
-
Human-breast cancer - Correlation of relapse and survival with amplification of the Her-2 neu oncogene
-
Slamon, D. J. et al. Human-Breast Cancer - Correlation of Relapse and Survival with Amplification of the Her-2 Neu Oncogene. Science 235, 177-182, doi: Doi 10.1126/Science.3798106 (1987).
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
-
11
-
-
67650071137
-
Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
-
Trachootham, D., Alexandre, J. & Huang, P. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat. Rev. Drug Discov. 8, 579-591, doi: Doi 10.1038/Nrd2803 (2009).
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 579-591
-
-
Trachootham, D.1
Alexandre, J.2
Huang, P.3
-
12
-
-
33748165596
-
Reactive oxygen species in cancer cells: Live by the sword, die by the sword
-
Schumacker, P. T. Reactive oxygen species in cancer cells: Live by the sword, die by the sword. Cancer Cell 10, 175-176, doi: Doi 10.1016/J. Ccr.2006.08.015 (2006).
-
(2006)
Cancer Cell
, vol.10
, pp. 175-176
-
-
Schumacker, P.T.1
-
13
-
-
79960427057
-
Selective killing of cancer cells by a small molecule targeting the stress response to ROS
-
Raj, L. et al. Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature 475, 231-234, doi: Doi 10.1038/Nature10167 (2011).
-
(2011)
Nature
, vol.475
, pp. 231-234
-
-
Raj, L.1
-
14
-
-
84887500713
-
Piperlongumine induces autophagy by targeting p38 signaling
-
Wang, Y. et al. Piperlongumine induces autophagy by targeting p38 signaling. Cell Death Dis. 4, e824, doi:10.1038/cddis.2013.358 (2013).
-
(2013)
Cell Death Dis.
, vol.4
, pp. e824
-
-
Wang, Y.1
-
15
-
-
22144443475
-
Drug resistance in cancer: Principles of emergence and prevention
-
Komarova, N. L. & Wodarz, D. Drug resistance in cancer: Principles of emergence and prevention. P. Natl. Acad. Sci. USA 102, 9714-9719, doi: Doi 10.1073/Pnas.0501870102 (2005).
-
(2005)
P. Natl. Acad. Sci. USA
, vol.102
, pp. 9714-9719
-
-
Komarova, N.L.1
Wodarz, D.2
-
16
-
-
84884688446
-
Target inhibition networks: Predicting selective combinations of druggable targets to block cancer survival pathways
-
Tang, J. et al. Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways. Plos Comput. Biol. 9, doi: Artn E1003226 Doi 10.1371/Journal. Pcbi.1003226 (2013).
-
(2013)
Plos Comput. Biol.
, pp. 9
-
-
Tang, J.1
-
17
-
-
84905449941
-
Doxorubicin and lapatinib combination nanomedicine for treating resistant breast cancer
-
Wang, H., Li, F., Du, C., Mahato, R. I. & Huang, Y. Doxorubicin and Lapatinib Combination Nanomedicine for Treating Resistant Breast Cancer. Mol. Pharm. doi:10.1021/mp400687w (2014).
-
(2014)
Mol. Pharm.
-
-
Wang, H.1
Li, F.2
Du, C.3
Mahato, R.I.4
Huang, Y.5
-
18
-
-
62449168519
-
TRAIL agonists on clinical trials for cancer therapy: The promises and the challenges
-
Bellail, A. C., Qi, L., Mulligan, P., Chhabra, V. & Hao, C. TRAIL agonists on clinical trials for cancer therapy: the promises and the challenges. Rev. Recent Clin. Trials 4, 34-41 (2009).
-
(2009)
Rev. Recent Clin. Trials
, vol.4
, pp. 34-41
-
-
Bellail, A.C.1
Qi, L.2
Mulligan, P.3
Chhabra, V.4
Hao, C.5
-
19
-
-
0346792725
-
TRAIL and apoptosis induction by TNF-family death receptors
-
Wang, S. & El-Deiry, W. S. TRAIL and apoptosis induction by TNF-family death receptors. Oncogene 22, 8628-8633, doi:10.1038/sj.onc.1207232 (2003).
-
(2003)
Oncogene
, vol.22
, pp. 8628-8633
-
-
Wang, S.1
El-Deiry, W.S.2
-
20
-
-
54249107246
-
The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway
-
Wang, S. The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway. Oncogene 27, 6207-6215, doi:10.1038/onc.2008.298 (2008).
-
(2008)
Oncogene
, vol.27
, pp. 6207-6215
-
-
Wang, S.1
-
21
-
-
84892917389
-
TRAIL-coated leukocytes that kill cancer cells in the circulation
-
Mitchell, M. J., Wayne, E., Rana, K., Schaffer, C. B. & King, M. R. TRAIL-coated leukocytes that kill cancer cells in the circulation. P. Natl. Acad. Sci. USA 111, 930-935, doi:10.1073/pnas.1316312111 (2014).
-
(2014)
P. Natl. Acad. Sci. USA
, vol.111
, pp. 930-935
-
-
Mitchell, M.J.1
Wayne, E.2
Rana, K.3
Schaffer, C.B.4
King, M.R.5
-
22
-
-
84875230886
-
On the TRAIL to successful cancer therapy?Predicting and counteracting resistance against TRAIL-based therapeutics
-
Dimberg, L. Y. et al. On the TRAIL to successful cancer therapy?Predicting and counteracting resistance against TRAIL-based therapeutics. Oncogene 32, 1341-1350, doi: Doi 10.1038/Onc.2012.164 (2013).
-
(2013)
Oncogene
, vol.32
, pp. 1341-1350
-
-
Dimberg, L.Y.1
-
23
-
-
33846243774
-
Blockade of transforming growth factor-beta-activated kinase 1 activity enhances TRAIL-induced apoptosis through activation of a caspase cascade
-
Choo, M. K. et al. Blockade of transforming growth factor-beta-activated kinase 1 activity enhances TRAIL-induced apoptosis through activation of a caspase cascade. Mol. Cancer Ther. 5, 2970-2976, doi: Doi 10.1158/1535-7163. Mct-06-0379 (2006).
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 2970-2976
-
-
Choo, M.K.1
-
24
-
-
32544435965
-
TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt
-
Szegezdi, E., Cahill, S., Meyer, M., O'Dwyer, M. & Samali, A. TRAIL sensitisation by arsenic trioxide is caspase-8 dependent and involves modulation of death receptor components and Akt. Brit. J. Cancer 94, 398-406, doi: Doi 10.1038/Sj. Bjc.6602954 (2006).
-
(2006)
Brit. J. Cancer
, vol.94
, pp. 398-406
-
-
Szegezdi, E.1
Cahill, S.2
Meyer, M.3
O'Dwyer, M.4
Samali, A.5
-
25
-
-
38849184654
-
Activation of p38 MAPK by reactive oxygen species is essential in a rat model of stress-induced gastric mucosal injury
-
Jia, Y. T. et al. Activation of p38 MAPK by reactive oxygen species is essential in a rat model of stress-induced gastric mucosal injury. J. Immunol. 179, 7808-7819 (2007).
-
(2007)
J. Immunol.
, vol.179
, pp. 7808-7819
-
-
Jia, Y.T.1
-
26
-
-
0037389558
-
Mitogen-activated protein kinases: New signaling pathways functioning in cellular responses to environmental stress
-
Cowan, K. J. & Storey, K. B. Mitogen-activated protein kinases: new signaling pathways functioning in cellular responses to environmental stress. J. Exp. Biol. 206, 1107-1115, doi: Doi 10.1242/Jeb.00220 (2003).
-
(2003)
J. Exp. Biol.
, vol.206
, pp. 1107-1115
-
-
Cowan, K.J.1
Storey, K.B.2
-
27
-
-
84867116994
-
Understanding the biology of triple-negative breast cancer
-
Criscitiello, C., Azim, H. A., Schouten, P. C., Linn, S. C. & Sotiriou, C. Understanding the biology of triple-negative breast cancer. Ann. Oncol. 23, 13-18, doi: Doi 10.1093/Annonc/Mds188 (2012).
-
(2012)
Ann. Oncol.
, vol.23
, pp. 13-18
-
-
Criscitiello, C.1
Azim, H.A.2
Schouten, P.C.3
Linn, S.C.4
Sotiriou, C.5
-
28
-
-
84867118148
-
Emerging targeted therapies in triple-negative breast cancer
-
Crown, J., O'Shaughnessy, J. & Gullo, G. Emerging targeted therapies in triple-negative breast cancer. Ann. Oncol. 23, 56-65, doi: Doi 10.1093/Annonc/Mds196 (2012).
-
(2012)
Ann. Oncol.
, vol.23
, pp. 56-65
-
-
Crown, J.1
O'Shaughnessy, J.2
Gullo, G.3
-
29
-
-
2942616456
-
Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. Intermediacy of H (2) O (2) - and p53-dependent pathways
-
Wang, S. et al. Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H (2) O (2) - and p53-dependent pathways. J. Biol. Chem. 279, 25535-25543, doi:10.1074/jbc. M400944200 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25535-25543
-
-
Wang, S.1
-
30
-
-
0019175583
-
Cardiac toxicity from antitumor therapy
-
Praga, C., Beretta, G. & Labianca, R. Cardiac toxicity from antitumor therapy. Oncology 37(Suppl 1), 51-58 (1980).
-
(1980)
Oncology
, vol.37
, pp. 51-58
-
-
Praga, C.1
Beretta, G.2
Labianca, R.3
-
31
-
-
0018560916
-
Adriamycin (doxorubicin) cardiotoxicity: A review
-
Chlebowski, R. T. Adriamycin (doxorubicin) cardiotoxicity: a review. West J. Med. 131, 364-368 (1979).
-
(1979)
West J. Med.
, vol.131
, pp. 364-368
-
-
Chlebowski, R.T.1
-
32
-
-
79956210767
-
Other options in the treatment of advanced breast cancer
-
Cobleigh, M. A. Other Options in the Treatment of Advanced Breast Cancer. Semin Oncol. 38, S11-Ss16, doi: Doi 10.1053/J. Seminoncol.2011.04.005 (2011).
-
(2011)
Semin Oncol.
, vol.38
, pp. S11-Ss16
-
-
Cobleigh, M.A.1
-
33
-
-
0035099833
-
The prognostic advantage of preoperative intratumoral injection of OK-432 for gastric cancer patients
-
Gochi, A., Orita, K., Fuchimoto, S., Tanaka, N. & Ogawa, N. The prognostic advantage of preoperative intratumoral injection of OK-432 for gastric cancer patients. Brit. J. Cancer 84, 443-451, doi: Doi 10.1054/Bjoc.2000.1599 (2001).
-
(2001)
Brit. J. Cancer
, vol.84
, pp. 443-451
-
-
Gochi, A.1
Orita, K.2
Fuchimoto, S.3
Tanaka, N.4
Ogawa, N.5
-
34
-
-
84903940811
-
Enhanced localization of anticancer drug in tumor tissue using polyethylenimineconjugated cationic liposomes
-
Han, H. D., Byeon, Y., Jeon, H. N. & Shin, B. C. Enhanced localization of anticancer drug in tumor tissue using polyethylenimineconjugated cationic liposomes. Nanoscale Res. Lett. 9, doi: Artn 209 Doi 10.1186/1556-276x-9-209 (2014).
-
(2014)
Nanoscale Res. Lett.
, pp. 9
-
-
Han, H.D.1
Byeon, Y.2
Jeon, H.N.3
Shin, B.C.4
-
35
-
-
33749822314
-
Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymerbased drug delivery systems
-
Lammers, T. et al. Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymerbased drug delivery systems. Neoplasia 8, 788-795, doi: Doi 10.1593/Neo.06436 (2006).
-
(2006)
Neoplasia
, vol.8
, pp. 788-795
-
-
Lammers, T.1
-
36
-
-
0034059465
-
Electrochemotherapy with cisplatin: Clinical experience in malignant melanoma patients
-
Sersa, G., Stabuc, B., Cemazar, M., Miklavcic, D. & Rudolf, Z. Electrochemotherapy with cisplatin: Clinical experience in malignant melanoma patients. Clin. Cancer Res. 6, 863-867 (2000).
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 863-867
-
-
Sersa, G.1
Stabuc, B.2
Cemazar, M.3
Miklavcic, D.4
Rudolf, Z.5
-
37
-
-
84867049694
-
Effect of intratumoral administration on biodistribution of Cu-64-labeled nanoshells
-
Xie, H., Goins, B., Bao, A. D., Wang, Z. J. & Phillips, W. T. Effect of intratumoral administration on biodistribution of Cu-64-labeled nanoshells. Int. J. Nanomed. 7, 2227-2238, doi: Doi 10.2147/Ijn. S30699 (2012).
-
(2012)
Int. J. Nanomed.
, vol.7
, pp. 2227-2238
-
-
Xie, H.1
Goins, B.2
Bao, A.D.3
Wang, Z.J.4
Phillips, W.T.5
-
38
-
-
77953413920
-
Improved antitumor activity and tumor targeting of NH2-terminal-specific PEGylated tumor necrosis factor-related apoptosis-inducing ligand
-
Chae, S. Y. et al. Improved Antitumor Activity and Tumor Targeting of NH2-Terminal-Specific PEGylated Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand. Mol. Cancer Ther. 9, 1719-1729, doi: Doi 10.1158/1535-7163. Mct-09-1076 (2010).
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 1719-1729
-
-
Chae, S.Y.1
-
39
-
-
84890434135
-
Human fucosyltransferase 6 enables prostate cancer metastasis to bone
-
Li, J. et al. Human fucosyltransferase 6 enables prostate cancer metastasis to bone. Brit. J. Cancer 109, 3014-3022, doi: Doi 10.1038/Bjc.2013.690 (2013).
-
(2013)
Brit. J. Cancer
, vol.109
, pp. 3014-3022
-
-
Li, J.1
-
40
-
-
84876116281
-
Ulinastatin exerts synergistic effects with taxotere and inhibits invasion and metastasis of breast cancer by blocking angiogenesis and the epithelial-mesenchymal transition
-
Gao, F. et al. Ulinastatin Exerts Synergistic Effects with Taxotere and Inhibits Invasion and Metastasis of Breast Cancer by Blocking Angiogenesis and the Epithelial-Mesenchymal Transition. Cancer Biother Radio 28, 218-225, doi: Doi 10.1089/Cbr.2011.1122 (2013).
-
(2013)
Cancer Biother Radio
, vol.28
, pp. 218-225
-
-
Gao, F.1
|