Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 20, 2015, Pages E2602-E2610

  Ma, Gary S ^a   Aznar, Nicolas ^a   Kalogriopoulos, Nicholas ^a   Midde, Krishna K ^a   Lopez Sanchez, Inmaculada ^a   Sato, Emi ^a   Dunkel, Ying ^a   Gallo, Richard L ^a,b   Ghosh, Pradipta ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Cell permeable GIV Girdin peptide; Fibrosis; Heterotrimeric G proteins; Invasion; Wound healing

Indexed keywords

COLLAGEN; DERMATOLOGICAL AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; GROWTH FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; PROTEIN TYROSINE KINASE; TAT G ALPHA INTERACTING VESICLE ASSOCIATED PROTEIN C TERMINUS PEPTIDE; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; CCDC88A PROTEIN, HUMAN; CELL PENETRATING PEPTIDE; SIGNAL PEPTIDE; TRANSACTIVATOR PROTEIN; VESICULAR TRANSPORT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CELL ACTIVATION; CELL FUNCTION; CELL INVASION; CELL MEMBRANE PERMEABILITY; CELL MIGRATION; CONTROLLED STUDY; DRUG EFFECT; HUMAN; HUMAN CELL; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; SCRATCHING; THERAPY EFFECT; WOUND HEALING; ANIMAL; CHEMISTRY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENETIC ENGINEERING; GENETIC TRANSDUCTION; GENETICS; HELA CELL LINE; METABOLISM; MOLECULAR MODEL; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PROCEDURES; SIGNAL TRANSDUCTION;

EUKARYOTA; GREAT ISLAND VIRUS; MUS;

ANIMALS; CELL-PENETRATING PEPTIDES; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE PRODUCTS, TAT; GENETIC ENGINEERING; GTP-BINDING PROTEINS; HELA CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICROFILAMENT PROTEINS; MODELS, MOLECULAR; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSDUCTION, GENETIC; VESICULAR TRANSPORT PROTEINS;

EID: 84929587553     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1505543112     Document Type: Article

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