Recombinant adeno-associated virus-mediated inhibition of microRNA-21 protects mice against the lethal schistosome infection by repressing both IL-13 and transforming growth factor beta 1 pathways

Hepatology

Volumn 61, Issue 6, 2015, Pages 2008-2017

  He, Xing ^a   Xie, Jun ^b   Zhang, Dongmei ^a   Su, Qin ^b   Sai, Xue ^a   Bai, Ruipu ^a   Chen, Chao ^a   Luo, Xufeng ^a   Gao, Guangping ^b   Pan, Weiqing ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 13; MICRORNA 21; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; MICRORNA; MIRN-21 MICRORNA, MOUSE; SMAD7 PROTEIN, MOUSE; TGFB1 PROTEIN, MOUSE;

ADENO ASSOCIATED VIRUS 8; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE REPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; LIVER FIBROSIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHISTOSOMIASIS; SIGNAL TRANSDUCTION; STELLATE CELL; UPREGULATION; VIRAL GENE THERAPY; VIRUS RECOMBINANT; ADENOVIRIDAE; ANIMAL; BAGG ALBINO MOUSE; LIVER DISEASES, PARASITIC; METABOLISM;

ADENOVIRIDAE; ANIMALS; DOWN-REGULATION; HEPATIC STELLATE CELLS; INTERLEUKIN-13; LIVER DISEASES, PARASITIC; MALE; MICE, INBRED BALB C; MICRORNAS; SCHISTOSOMIASIS; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84929581812     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27671     Document Type: Article

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