PiRNA-directed cleavage of meiotic transcripts regulates spermatogenesis

Genes and Development

Volumn 29, Issue 10, 2015, Pages 1032-1044

  Goh, Wee Siong Sho ^a,b,e   Falciatori, Ilaria ^a,b,c   Tam, Oliver H ^b   Burgess, Ralph ^a,b   Meikar, Oliver ^d   Kotaja, Noora ^d   Hammell, Molly ^b   Hannon, Gregory J ^a,b,c  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b WATSON SCHOOL OF BIOLOGICAL SCIENCES   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF TURKU   (Finland)

^e INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

Exogenous piRNAs; MIWI; Pachytene piRNAs; Ping pong cycle; RNA cleavage; Spermatogenesis defect

Indexed keywords

PIWI INTERACTING RNA; SMALL INTERFERING RNA; TRANSPOSON;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CHROMOSOME 17; ESSENTIAL GENE; GENE EXPRESSION; GENE TARGETING; GENETIC CODE; HUMAN; MALE; MALE STERILITY; MEIOSIS; MOUSE; NONHUMAN; PACHYTENE; PRIORITY JOURNAL; RNA CLEAVAGE; RNA TRANSCRIPTION; SPERMATOGENESIS; TRANSCRIPTION INITIATION SITE; TRANSPOSON; ANIMAL; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; MALE INFERTILITY; METABOLISM; OPEN READING FRAME; TESTIS;

ANIMALS; DNA TRANSPOSABLE ELEMENTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE SILENCING; HUMANS; INFERTILITY, MALE; MALE; MEIOSIS; MICE; OPEN READING FRAMES; PACHYTENE STAGE; RNA, SMALL INTERFERING; SPERMATOGENESIS; TESTIS;

EID: 84929575533     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.260455.115     Document Type: Article

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