-
1
-
-
2542461241
-
Optimal low-density lipoprotein is 50 to 70 mg/dl: Lower is better and physiologically normal
-
O'Keefe JH Jr, Cordain L, Harris WH, et al. Optimal low-density lipoprotein is 50 to 70 mg/dl: lower is better and physiologically normal. J Am Coll Cardiol. 2004;43:2142-2146.
-
(2004)
J Am Coll Cardiol.
, vol.43
, pp. 2142-2146
-
-
O'Keefe, J.H.1
Cordain, L.2
Harris, W.H.3
-
2
-
-
15944410609
-
Intensive lipid lowering with atorvastatin in patients with stable coronary disease
-
LaRosa JC, Grundy SM, Waters DD, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med. 2005;352:1425-1435.
-
(2005)
N Engl J Med.
, vol.352
, pp. 1425-1435
-
-
Larosa, J.C.1
Grundy, S.M.2
Waters, D.D.3
-
3
-
-
33745156066
-
What the statin trials have taught us
-
Waters DD. What the statin trials have taught us. Am J Cardiol. 2006;98:129-134.
-
(2006)
Am J Cardiol.
, vol.98
, pp. 129-134
-
-
Waters, D.D.1
-
4
-
-
3142729178
-
Implications of recent clinical trials for the National cholesterol Education Program Adult treatment Panel III guidelines
-
Grundy SM, Cleeman JI, Merz CN, et al. Implications of recent clinical trials for the National cholesterol Education Program Adult treatment Panel III guidelines. Circulation. 2004;110:227-239.
-
(2004)
Circulation.
, vol.110
, pp. 227-239
-
-
Grundy, S.M.1
Cleeman, J.I.2
Merz, C.N.3
-
5
-
-
84870941622
-
Modifiable factors associated with failure to attain low-density lipopro-tein cholesterol goal at 6 months after acute myocardial infarction
-
Martin SS, Gosch K, Kulkarni KR, et al. Modifiable factors associated with failure to attain low-density lipopro-tein cholesterol goal at 6 months after acute myocardial infarction. Am Heart J. 2013;165:26-33.e3.
-
(2013)
Am Heart J.
, vol.165
, pp. 26-26e3
-
-
Martin, S.S.1
Gosch, K.2
Kulkarni, K.R.3
-
6
-
-
80053630176
-
Frequency and correlates of treatment intensification for elevated cholesterol levels in patients with cardiovascular disease
-
Virani SS, Woodard LD, Chitwood SS, et al. Frequency and correlates of treatment intensification for elevated cholesterol levels in patients with cardiovascular disease. Am Heart J. 2011;162:725-732.e1.
-
(2011)
Am Heart J.
, vol.162
, pp. 725-725e1
-
-
Virani, S.S.1
Woodard, L.D.2
Chitwood, S.S.3
-
7
-
-
84861747780
-
Understanding Statin Use in America and Gaps in Patient Education (USAGE): An internet-based survey of 10, 138 current and former statin users
-
Cohen JD, Brinton EA, Ito MK, et al. Understanding Statin Use in America and Gaps in Patient Education (USAGE): an internet-based survey of 10, 138 current and former statin users. J Clin Lipidol. 2012;6:208-215.
-
(2012)
J Clin Lipidol.
, vol.6
, pp. 208-215
-
-
Cohen, J.D.1
Brinton, E.A.2
Ito, M.K.3
-
8
-
-
77549087054
-
Statins and risk of incident diabetes: A collaborative meta-Analysis of randomised statin trials
-
Sattar N, Preiss D, Murray HM, et al. Statins and risk of incident diabetes: a collaborative meta-Analysis of randomised statin trials. Lancet. 2010;375:735-742.
-
(2010)
Lancet.
, vol.375
, pp. 735-742
-
-
Sattar, N.1
Preiss, D.2
Murray, H.M.3
-
9
-
-
79959428660
-
Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: A meta-Analysis
-
Preiss D, Seshasai SR, Welsh P, et al. Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-Analysis. JAMA. 2011;305:2556-2564.
-
(2011)
JAMA.
, vol.305
, pp. 2556-2564
-
-
Preiss, D.1
Seshasai, S.R.2
Welsh, P.3
-
10
-
-
84929519916
-
-
FDA Drug Safety Communication. Important safety label changes to cholesterol-lowering statin drugs Accessed February 28, 2012
-
FDA Drug Safety Communication. Important safety label changes to cholesterol-lowering statin drugs. Available at: http://www.fda.gov/drugs/drugsafety/ucm293101.htm. Accessed February 28, 2012.
-
-
-
-
11
-
-
0032542277
-
Clinical trial experience with extended-release niacin (Niaspan): Dose-escalation study
-
Goldberg AC. Clinical trial experience with extended-release niacin (Niaspan): dose-escalation study. Am J Car-diol. 1998;82:35U-38U.
-
(1998)
Am J Car-diol.
, vol.82
, pp. 35U-38U
-
-
Goldberg, A.C.1
-
12
-
-
0023625355
-
Effects of fe-nofibrate on plasma lipoproteins in hypercholesterolemia and combined hyperlipidemia
-
Knopp RH, Brown WV, Dujovne CA, et al. Effects of fe-nofibrate on plasma lipoproteins in hypercholesterolemia and combined hyperlipidemia. Am J Med. 1987;83:50-59.
-
(1987)
Am J Med.
, vol.83
, pp. 50-59
-
-
Knopp, R.H.1
Brown, W.V.2
Dujovne, C.A.3
-
13
-
-
0038054346
-
Evaluation of the efficacy, safety, and tolerability of ezetimibe in primary hypercholesterolaemia: A pooled analysis from two controlled phase III clinical studies
-
Knopp RH, Dujovne CA, Le Beaut A, et al. Evaluation of the efficacy, safety, and tolerability of ezetimibe in primary hypercholesterolaemia: a pooled analysis from two controlled phase III clinical studies. Int J Clin Pract. 2003; 57:363-368.
-
(2003)
Int J Clin Pract.
, vol.57
, pp. 363-368
-
-
Knopp, R.H.1
Dujovne, C.A.2
Le Beaut, A.3
-
14
-
-
0034774221
-
Effectiveness of colesevelam hydrochloride in decreasing LDL cholesterol in patients with primary hypercholesterolemia: A 24-week randomized controlled trial
-
Insull W Jr, Toth P, Mullican W, et al. Effectiveness of colesevelam hydrochloride in decreasing LDL cholesterol in patients with primary hypercholesterolemia: a 24-week randomized controlled trial. Mayo Clin Proc. 2001;76:971-982.
-
(2001)
Mayo Clin Proc.
, vol.76
, pp. 971-982
-
-
Insull, W.1
Toth, P.2
Mullican, W.3
-
15
-
-
84857368169
-
Mipomersen: A safe and effective antisense therapy adjunct to statins in patients with hypercholesterolemia
-
Ricotta DN, Frishman WH. Mipomersen: a safe and effective antisense therapy adjunct to statins in patients with hypercholesterolemia. Cardiol Rev. 2012;20:90-95.
-
(2012)
Cardiol Rev.
, vol.20
, pp. 90-95
-
-
Ricotta, D.N.1
Frishman, W.H.2
-
16
-
-
77949485460
-
Mipomersen, an apo-lipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: A randomised, double-blind, placebo-controlled trial
-
Raal FJ, Santos RD, Blom DJ, et al. Mipomersen, an apo-lipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial. Lancet. 2010;375:998-1006.
-
(2010)
Lancet.
, vol.375
, pp. 998-1006
-
-
Raal, F.J.1
Santos, R.D.2
Blom, D.J.3
-
17
-
-
84888090979
-
Mipomersen, an apolipoprotein B synthesis inhibitor, reduces atherogenic lipoproteins in patients with severe hypercholesterol-emia at high cardiovascular risk: A randomized, double-blind, placebo-controlled trial
-
Thomas GS, Cromwell WC, Ali S, et al. Mipomersen, an apolipoprotein B synthesis inhibitor, reduces atherogenic lipoproteins in patients with severe hypercholesterol-emia at high cardiovascular risk: a randomized, double-blind, placebo-controlled trial. J Am Coll Cardiol. 2013;62:2178-2184.
-
(2013)
J Am Coll Cardiol.
, vol.62
, pp. 2178-2184
-
-
Thomas, G.S.1
Cromwell, W.C.2
Ali, S.3
-
18
-
-
77951069859
-
Effect of mipo-mersen, an apolipoprotein B synthesis inhibitor, on low-density lipoprotein cholesterol in patients with familial hypercholesterolemia
-
Akdim F, Visser ME, Tribble DL, et al. Effect of mipo-mersen, an apolipoprotein B synthesis inhibitor, on low-density lipoprotein cholesterol in patients with familial hypercholesterolemia. Am J Cardiol. 2010;105:1413-1419.
-
(2010)
Am J Cardiol.
, vol.105
, pp. 1413-1419
-
-
Akdim, F.1
Visser, M.E.2
Tribble, D.L.3
-
19
-
-
84860615159
-
Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: A randomized, double-blind, placebo-controlled trial
-
Visser ME, Wagener G, Baker BF, et al. Mipomersen, an apolipoprotein B synthesis inhibitor, lowers low-density lipoprotein cholesterol in high-risk statin-intolerant patients: a randomized, double-blind, placebo-controlled trial. Eur Heart J. 2012;33:1142-1149.
-
(2012)
Eur Heart J.
, vol.33
, pp. 1142-1149
-
-
Visser, M.E.1
Wagener, G.2
Baker, B.F.3
-
20
-
-
79959661095
-
Efficacy of apolipo-protein B synthesis inhibition in subjects with mild-to-moderate hyperlipidaemia
-
Akdim F, Tribble DL, Flaim JD, et al. Efficacy of apolipo-protein B synthesis inhibition in subjects with mild-to-moderate hyperlipidaemia. Eur Heart J. 2011;32:2650-2659.
-
(2011)
Eur Heart J.
, vol.32
, pp. 2650-2659
-
-
Akdim, F.1
Tribble, D.L.2
Flaim, J.D.3
-
21
-
-
84859408689
-
Antisense inhibition of apoB synthesis with mipomersen reduces plasma apoC-III and apoC-III-containing lipoproteins
-
Furtado JD, Wedel MK, Sacks FM. Antisense inhibition of apoB synthesis with mipomersen reduces plasma apoC-III and apoC-III-containing lipoproteins. J Lipid Res. 2012;53:784-791.
-
(2012)
J Lipid Res.
, vol.53
, pp. 784-791
-
-
Furtado, J.D.1
Wedel, M.K.2
Sacks, F.M.3
-
23
-
-
80054113117
-
Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: Implications for classification and disease risk
-
Calandra S, Tarugi P, Speedy HE, et al. Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classification and disease risk. J Lipid Res. 2011;52: 1885-1926.
-
(2011)
J Lipid Res.
, vol.52
, pp. 1885-1926
-
-
Calandra, S.1
Tarugi, P.2
Speedy, H.E.3
-
24
-
-
84879898680
-
New therapies to reduce low-density lipoprotein cholesterol
-
Wierzbicki AS, Viljoen A, Hardman TC, et al. New therapies to reduce low-density lipoprotein cholesterol. Curr Opin Cardiol. 2013;28:452-457.
-
(2013)
Curr Opin Cardiol.
, vol.28
, pp. 452-457
-
-
Wierzbicki, A.S.1
Viljoen, A.2
Hardman, T.C.3
-
25
-
-
84890562042
-
Recent developments in the treatment of familial hypercholesterolemia: A review of several new drug classes
-
Wilkinson MJ, Davidson MH. Recent developments in the treatment of familial hypercholesterolemia: a review of several new drug classes. Curr Treat Options Cardiovasc Med. 2013;15:696-705.
-
(2013)
Curr Treat Options Cardiovasc Med.
, vol.15
, pp. 696-705
-
-
Wilkinson, M.J.1
Davidson, M.H.2
-
26
-
-
84871945617
-
Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hyper-cholesterolaemia: A single-Arm, open-label, phase 3 study
-
Cuchel M, Meagher EA, du Toit Theron H, et al. Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hyper-cholesterolaemia: a single-Arm, open-label, phase 3 study. Lancet. 2013;381:40-46.
-
(2013)
Lancet.
, vol.381
, pp. 40-46
-
-
Cuchel, M.1
Meagher, E.A.2
Du Toit Theron, H.3
-
27
-
-
34548175537
-
Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis
-
Qian YW, Schmidt RJ, Zhang Y, et al. Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis. J Lipid Res. 2007;48: 1488-1498.
-
(2007)
J Lipid Res.
, vol.48
, pp. 1488-1498
-
-
Qian, Y.W.1
Schmidt, R.J.2
Zhang, Y.3
-
28
-
-
84898597389
-
Antihyperlipidemic therapies targeting PCSK9
-
Weinreich M, Frishman WH. Antihyperlipidemic therapies targeting PCSK9. Cardiol Rev. 2014;22:140-146.
-
(2014)
Cardiol Rev.
, vol.22
, pp. 140-146
-
-
Weinreich, M.1
Frishman, W.H.2
-
29
-
-
0037603589
-
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
-
Abifadel M, Varret M, Rabès JP, et al. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat Genet. 2003;34:154-156.
-
(2003)
Nat Genet.
, vol.34
, pp. 154-156
-
-
Abifadel, M.1
Varret, M.2
Rabès, J.P.3
-
30
-
-
2442670243
-
Mutations in the PCSK9 gene in Norwegian subjects with autosomal dominant hypercholesterolemia
-
Leren TP. Mutations in the PCSK9 gene in Norwegian subjects with autosomal dominant hypercholesterolemia. Clin Genet. 2004;65:419-422.
-
(2004)
Clin Genet.
, vol.65
, pp. 419-422
-
-
Leren, T.P.1
-
31
-
-
33645103550
-
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
-
Cohen JC, Boerwinkle E, Mosley TH Jr, et al. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med. 2006;354:1264-1272.
-
(2006)
N Engl J Med.
, vol.354
, pp. 1264-1272
-
-
Cohen, J.C.1
Boerwinkle, E.2
Mosley, T.H.3
-
32
-
-
3943060193
-
Statins upre-gulate PCSK9, the gene encoding the proprotein conver-tase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia
-
Dubuc G, Chamberland A, Wassef H, et al. Statins upre-gulate PCSK9, the gene encoding the proprotein conver-tase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia. Arterioscler Thromb Vasc Biol. 2004;24:1454-1459.
-
(2004)
Arterioscler Thromb Vasc Biol.
, vol.24
, pp. 1454-1459
-
-
Dubuc, G.1
Chamberland, A.2
Wassef, H.3
-
33
-
-
84879549184
-
New therapeutic principles in dyslipidaemia: Focus on LDL and Lp (a) lowering drugs
-
Norata GD, Ballantyne CM, Catapano AL. New therapeutic principles in dyslipidaemia: focus on LDL and Lp (a) lowering drugs. Eur Heart J. 2013;34:1783-1789.
-
(2013)
Eur Heart J.
, vol.34
, pp. 1783-1789
-
-
Norata, G.D.1
Ballantyne, C.M.2
Catapano, A.L.3
-
34
-
-
84858638369
-
Effect of a monoclonal antibody to PCSK9 on LDL cholesterol
-
Stein EA, Mellis S, Yancopoulos GD, et al. Effect of a monoclonal antibody to PCSK9 on LDL cholesterol. N Engl J Med. 2012;366:1108-1118.
-
(2012)
N Engl J Med.
, vol.366
, pp. 1108-1118
-
-
Stein, E.A.1
Mellis, S.2
Yancopoulos, G.D.3
-
35
-
-
84863494422
-
Effect of a monoclonal antibody to PCSK9, REGN727/SAR236553, to reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy: A phase 2 randomised controlled trial
-
Stein EA, Gipe D, Bergeron J, et al. Effect of a monoclonal antibody to PCSK9, REGN727/SAR236553, to reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy: a phase 2 randomised controlled trial. Lancet. 2012;380:29-36.
-
(2012)
Lancet.
, vol.380
, pp. 29-36
-
-
Stein, E.A.1
Gipe, D.2
Bergeron, J.3
-
36
-
-
84862219022
-
Safety and efficacy of a monoclonal antibody to proprotein conver-tase subtilisin/kexin type 9 serine protease, SAR236553/REGN727, in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy
-
McKenney JM, Koren MJ, Kereiakes DJ, et al. Safety and efficacy of a monoclonal antibody to proprotein conver-tase subtilisin/kexin type 9 serine protease, SAR236553/REGN727, in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy. J Am Coll Cardiol. 2012;59:2344-2353.
-
(2012)
J Am Coll Cardiol.
, vol.59
, pp. 2344-2353
-
-
McKenney, J.M.1
Koren, M.J.2
Kereiakes, D.J.3
-
37
-
-
84868689211
-
Atorvastatin with or without an antibody to PCSK9 in primary hyper-cholesterolemia
-
Roth EM, McKenney JM, Hanotin C, et al. Atorvastatin with or without an antibody to PCSK9 in primary hyper-cholesterolemia. N Engl J Med. 2012;367:1891-1900.
-
(2012)
N Engl J Med.
, vol.367
, pp. 1891-1900
-
-
Roth, E.M.1
McKenney, J.M.2
Hanotin, C.3
-
39
-
-
84892679366
-
Efficacy and safety of Longer-Term administration of evolocumab (AMG 145) in patients with hypercholesterolemia: 52-Week results from the open-label study of Long-Term Evaluation against LDL-C (OSLER) randomized trial
-
Koren MJ, Giugliano RP, Raal FJ, et al. Efficacy and safety of Longer-Term administration of evolocumab (AMG 145) in patients with hypercholesterolemia: 52-Week results from the open-label study of Long-Term Evaluation against LDL-C (OSLER) randomized trial. Circulation. 2013;129:234-243.
-
(2013)
Circulation.
, vol.129
, pp. 234-243
-
-
Koren, M.J.1
Giugliano, R.P.2
Raal, F.J.3
-
40
-
-
84871226706
-
AMP-Activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism
-
Pinkosky SL, Filippov S, Srivastava RA, et al. AMP-Activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. J Lipid Res. 2013;54:134-151.
-
(2013)
J Lipid Res.
, vol.54
, pp. 134-151
-
-
Pinkosky, S.L.1
Filippov, S.2
Srivastava, R.A.3
-
41
-
-
84884366154
-
Efficacy and safety of a novel dual modulator of adenosine triphosphate-citrate lyase and adenosine monophosphate-Activated protein kinase in patients with hypercholesterolemia: Results of a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial
-
Ballantyne CM, Davidson MH, Macdougall DE, et al. Efficacy and safety of a novel dual modulator of adenosine triphosphate-citrate lyase and adenosine monophosphate-Activated protein kinase in patients with hypercholesterolemia: results of a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial. J Am Coll Cardiol. 2013;62:1154-1162.
-
(2013)
J Am Coll Cardiol.
, vol.62
, pp. 1154-1162
-
-
Ballantyne, C.M.1
Davidson, M.H.2
De, M.3
-
42
-
-
36348975228
-
Effects of torce-trapib in patients at high risk for coronary events
-
Barter PJ, Caulfield M, Eriksson M, et al. Effects of torce-trapib in patients at high risk for coronary events. N Engl J Med. 2007;357:2109-2122.
-
(2007)
N Engl J Med.
, vol.357
, pp. 2109-2122
-
-
Barter, P.J.1
Caulfield, M.2
Eriksson, M.3
-
43
-
-
48449087714
-
Cholesteryl ester transfer protein inhibition for coronary heart disease prevention: Real hope or despair?
-
Frishman WH, Barkowski RS. Cholesteryl ester transfer protein inhibition for coronary heart disease prevention: real hope or despair? Am J Med. 2008;121:644-646.
-
(2008)
Am J Med.
, vol.121
, pp. 644-646
-
-
Frishman, W.H.1
Barkowski, R.S.2
-
44
-
-
84901626093
-
High-density lipoprotein Functionality in coronary artery disease
-
Kosmas CE, Christodoulidis G, Cheng JW, et al. High-density lipoprotein Functionality in coronary artery disease. Am J Med Sci. 2014;347:504-508.
-
(2014)
Am J Med Sci.
, vol.347
, pp. 504-508
-
-
Kosmas, C.E.1
Christodoulidis, G.2
Cheng, J.W.3
-
45
-
-
84870045994
-
Effects of dalce-trapib in patients with a recent acute coronary syndrome
-
Schwartz GG, Olsson AG, Abt M, et al. Effects of dalce-trapib in patients with a recent acute coronary syndrome. N Engl J Med. 2012;367:2089-2099.
-
(2012)
N Engl J Med.
, vol.367
, pp. 2089-2099
-
-
Schwartz, G.G.1
Olsson, A.G.2
Abt, M.3
-
46
-
-
78549235583
-
Safety of anace-trapib in patients with or at high risk for coronary heart disease
-
Cannon CP, Shah S, Dansky HM, et al. Safety of anace-trapib in patients with or at high risk for coronary heart disease. N Engl J Med. 2010;363:2406-2415.
-
(2010)
N Engl J Med.
, vol.363
, pp. 2406-2415
-
-
Cannon, C.P.1
Shah, S.2
Dansky, H.M.3
-
47
-
-
81255125373
-
Effects of the CETP inhibitor evacetrapib administered as monotherapy or in combination with statins on HDL and LDL cholesterol: A randomized controlled trial
-
Nicholls SJ, Brewer HB, Kastelein JJ, et al. Effects of the CETP inhibitor evacetrapib administered as monotherapy or in combination with statins on HDL and LDL cholesterol: a randomized controlled trial. JAMA. 2011;306:2099-2109.
-
(2011)
JAMA.
, vol.306
, pp. 2099-2109
-
-
Nicholls, S.J.1
Brewer, H.B.2
Kastelein, J.J.3
-
48
-
-
77958518713
-
Liver X receptors: A potential therapeutic target for modulating the atherosclerotic process
-
Parikh N, Frishman WH. Liver X receptors: a potential therapeutic target for modulating the atherosclerotic process. Cardiol Rev. 2010;18:269-274.
-
(2010)
Cardiol Rev.
, vol.18
, pp. 269-274
-
-
Parikh, N.1
Frishman, W.H.2
-
49
-
-
0034669171
-
Role of LXRs in control of lipogenesis
-
Schultz JR, Tu H, Luk A, et al. Role of LXRs in control of lipogenesis. Genes Dev. 2000;14:2831-2838.
-
(2000)
Genes Dev.
, vol.14
, pp. 2831-2838
-
-
Schultz, J.R.1
Tu, H.2
Luk, A.3
-
50
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
-
Peet DJ, Turley SD, Ma W, et al. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell. 1998;93:693-704.
-
(1998)
Cell.
, vol.93
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
-
51
-
-
34547652884
-
Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE
-
Bradley MN, Hong C, Chen M, et al. Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE. J Clin Invest. 2007;117:2337-2346.
-
(2007)
J Clin Invest.
, vol.117
, pp. 2337-2346
-
-
Bradley, M.N.1
Hong, C.2
Chen, M.3
-
52
-
-
70849088458
-
LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse
-
Quinet EM, Basso MD, Halpern AR, et al. LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse. J Lipid Res. 2009;50:2358-2370.
-
(2009)
J Lipid Res.
, vol.50
, pp. 2358-2370
-
-
Quinet, E.M.1
Basso, M.D.2
Halpern, A.R.3
|