Antisense inhibition of apoB synthesis with mipomersen reduces plasma apoC-III and apoC-III-containing lipoproteins

Journal of Lipid Research

Volumn 53, Issue 4, 2012, Pages 784-791

  Furtado, Jeremy D ^a   Wedel, Mark K ^b   Sacks, Frank M ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b ISIS PHARMACEUTICALS   (United States)

Author keywords

Apolipoprotein B; Apolipoprotein C III; Apolipoprotein E; Atherosclerosis; Cholesterol

Indexed keywords

APOLIPOPROTEIN B; APOLIPOPROTEIN C3; LIPOPROTEIN; MIPOMERSEN; PLACEBO;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CARDIOVASCULAR RISK; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; ENZYME INHIBITION; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; IMMUNOAFFINITY CHROMATOGRAPHY; ISCHEMIC HEART DISEASE; LIPOPROTEIN BLOOD LEVEL; LOADING DRUG DOSE; MALE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RISK REDUCTION; TREATMENT DURATION; TREATMENT RESPONSE; ULTRACENTRIFUGATION;

ADOLESCENT; ADULT; AGED; APOLIPOPROTEIN C-III; APOLIPOPROTEINS B; APOLIPOPROTEINS E; BODY MASS INDEX; CHOLESTEROL, LDL; CHROMATOGRAPHY, AFFINITY; FEMALE; HUMANS; HYPERCHOLESTEROLEMIA; LIPOPROTEINS, VLDL; MALE; MIDDLE AGED; OLIGONUCLEOTIDES; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TRIGLYCERIDES; ULTRACENTRIFUGATION; YOUNG ADULT;

EID: 84859408689     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.P021717     Document Type: Article

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