Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 14, 2015, Pages 4363-4368

  Minchin, James E N ^a,b   Dahlman, Ingrid ^c   Harvey, Christopher J ^b   Mejhert, Niklas ^c   Singh, Manvendra K ^d,e   Epstein, Jonathan A ^d   Arner, Peter ^c   Torres Vázquez, Jesús ^f   Rawls, John F ^a   Cone, Roger D ^g  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e DUKE NUS MEDICAL SCHOOL   (Singapore)

^f NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adipose development; Body fat distribution; Extracellular matrix; Insulin resistance; Zebrafish

Indexed keywords

COLLAGEN TYPE 5; COLLAGEN TYPE V ALPHA 1; PLEXIN; PLEXIN D1; UNCLASSIFIED DRUG; COL5A1 PROTEIN, HUMAN; INSULIN; LIPID; MEMBRANE PROTEIN; MESSENGER RNA; NERVE CELL ADHESION MOLECULE; NERVE PROTEIN; PLXND1 PROTEIN, HUMAN; PLXND1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY FAT DISTRIBUTION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENETIC ANALYSIS; GLUCOSE TOLERANCE TEST; HETEROZYGOTE; HOMOZYGOTE; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRAABDOMINAL FAT; LIPID DIET; LIPID STORAGE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN DEFICIENCY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBCUTANEOUS FAT; ZEBRA FISH; ANIMAL; BIOSYNTHESIS; BODY COMPOSITION; CHEMISTRY; CYTOLOGY; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION REGULATION; METABOLISM; MOUSE; MUTATION; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

DANIO RERIO;

ANIMALS; BODY COMPOSITION; CELL ADHESION MOLECULES, NEURONAL; CELL PROLIFERATION; COLLAGEN TYPE V; ENDOTHELIAL CELLS; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INSULIN; INTRA-ABDOMINAL FAT; LIPIDS; MEMBRANE GLYCOPROTEINS; MICE; MUTATION; NERVE TISSUE PROTEINS; OBESITY; RNA, MESSENGER; SIGNAL TRANSDUCTION; ZEBRAFISH;

EID: 84929493842     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1416412112     Document Type: Article

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