Anti-Yo antibody uptake and interaction with its intracellular target antigen causes Purkinje cell death in rat cerebellar slice cultures: A possible mechanism for paraneoplastic cerebellar degeneration in humans with gynecological or breast cancers

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Greenlee, John E ^a,b   Clawson, Susan A ^b   Hill, Kenneth E ^b   Wood, Blair ^b   Clardy, Stacey L ^a,b   Tsunoda, Ikuo ^c   Carlson, Noel G ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CALBINDIN; CALMODULIN; IMMUNOGLOBULIN G ANTIBODY; PROTEIN PCP 2; UNCLASSIFIED DRUG; YO ANTIBODY; AUTOANTIBODY; CDR2 PROTEIN, HUMAN; IMMUNOGLOBULIN G; NERVE PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ARTICLE; BREAST CANCER; CELL DEATH; CELL INFILTRATION; CELL INTERACTION; CELL LINEAGE; CEREBELLUM; CONTROLLED STUDY; CYTOTOXICITY; FEMALE GENITAL TRACT CANCER; HUMAN; HUMAN CELL; MACROPHAGE; MICROGLIA; NONHUMAN; PARANEOPLASTIC NEUROPATHY; PROTEIN TRANSPORT; PURKINJE CELL; RAT; TISSUE CULTURE; ANIMAL; BREAST TUMOR; FEMALE; FEMALE GENITAL TRACT TUMOR; IMMUNOLOGY; PATHOLOGY; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; AUTOANTIBODIES; BREAST NEOPLASMS; CELL DEATH; CEREBELLUM; FEMALE; GENITAL NEOPLASMS, FEMALE; HUMANS; IMMUNOGLOBULIN G; NERVE TISSUE PROTEINS; PARANEOPLASTIC CEREBELLAR DEGENERATION; PURKINJE CELLS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84929492870     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0123446     Document Type: Article

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