Specific deletion of AMP-activated protein kinase (a1 AMPK) in murine oocytes alters junctional protein expression and mitochondrial physiology

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Bertoldo, Michael J ^a,e   Guibert, Edith ^a   Faure, Melanie ^a   Ramé, Christelle ^a   Foretz, Marc ^b,c,d   Viollet, Benoit ^b,c,d   Dupont, Joëlle ^a   Froment, Pascal ^a  

^a UMR85 PHYSIOLOGIE DE LA REPRODUCTION ET DES COMPORTEMENTS   (France)

^b INSTITUT COCHIN   (France)

^c CNRS   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADENOSINE TRIPHOSPHATE; AMP ACTIVATED PROTEIN KINASE ALPHA 1 SUBUNIT; BETA CATENIN; CONNEXIN 37; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOCHROME C; HISTONE DEACETYLASE; HISTONE H3; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NERVE CELL ADHESION MOLECULE; OCCLUDIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SIRTUIN 1; UNCLASSIFIED DRUG; AMPK ALPHA1 SUBUNIT, MOUSE; CADHERIN; GAP JUNCTION PROTEIN;

ALPHA 1 AMPK GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COMMUNICATION; CELL STIMULATION; CELLULAR ENERGY HOMEOSTASIS; CONTROLLED STUDY; CUMULUS CELL; CUMULUS OOCYTE COMPLEX; DOWN REGULATION; EMBRYO; ENERGY YIELD; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; FEMALE GENITAL SYSTEM FUNCTION; FEMALE GENITAL TRACT PARAMETERS; FEMALE SUBFERTILITY; FERTILIZATION IN VITRO; GENE DELETION; GENE INACTIVATION; GRANULOSA CELL; HISTOLOGY; HISTONE ACETYLATION; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INTRACELLULAR SIGNALING; JUNCTIONAL PROTEIN EXPRESSION; LITTER SIZE; METAPHASE; MITOCHONDRIAL DYNAMICS; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OOCYTE; OOCYTE QUALITY; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSGENIC MOUSE; ANIMAL; C57BL MOUSE; ENERGY METABOLISM; GAP JUNCTION; MALE; METABOLISM; MITOCHONDRION; OOCYTE DEVELOPMENT; OVARY FOLLICLE; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

MURINAE; MUS; MUS MUSCULUS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CADHERINS; CELL COMMUNICATION; CONNEXINS; ENERGY METABOLISM; FEMALE; GAP JUNCTIONS; GRANULOSA CELLS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; OOCYTES; OOGENESIS; OVARIAN FOLLICLE; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 84929492502     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0119680     Document Type: Article

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