White matter integrity supports BOLD signal variability and cognitive performance in the aging human brain

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Burzynska, Agnieszka Z ^a   Wong, Chelsea N ^a   Voss, Michelle W ^b   Cooke, Gillian E ^a   McAuley, Edward ^a   Kramer, Arthur F ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b E11 SSH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AGING; ARTICLE; BOLD SIGNAL; BRAIN FUNCTION; COGNITION; FEMALE; GRAY MATTER; HUMAN; HUMAN EXPERIMENT; INTELLIGENCE; LINGUISTICS; MALE; MEMORY; MENTAL PERFORMANCE; NORMAL HUMAN; PARTIAL LEAST SQUARES REGRESSION; PERCEPTION; STATISTICAL MODEL; VERY ELDERLY; WHITE MATTER; BLOOD; BRAIN MAPPING; MIDDLE AGED; PHYSIOLOGY;

OXYGEN;

ADULT; AGED; AGING; BRAIN MAPPING; COGNITION; FEMALE; HUMANS; MALE; MEMORY; MIDDLE AGED; OXYGEN; WHITE MATTER;

EID: 84929484686     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0120315     Document Type: Article

References (87)

1. Rajah MN, D'Esposito M (2005) Region-specific changes in prefrontal function with age: a review of PET and fMRI studies on working and episodic memory. Brain 128: 1964-1983. Available: http://www. ncbi.nlm.nih.gov/pubmed/16049041. Accessed 2010 Jul 27. PMID: 16049041
2. Hafkemeijer A, van der Grond J, Rombouts SARB (2012) Imaging the default mode network in aging and dementia. Biochim Biophys Acta 1822: 431-441. Available: http://www.ncbi.nlm.nih.gov/pubmed/ 21807094. Accessed 2014 Jul 26. doi: 10.1016/j.bbadis.2011.07.008 PMID: 21807094
3. Madden DJ, Bennett IJ, Burzynska A, Potter GG, Chen N-K, Song AW (2012) Diffusion tensor imaging of cerebral white matter integrity in cognitive aging. Biochim Biophys Acta 1822: 386-400. Available: http://www.ncbi.nlm.nih.gov/pubmed/21871957. doi: 10.1016/j.bbadis.2011.08.003 PMID: 21871957
4. Grady CL, Garrett DD (2014) Understanding variability in the BOLD signal and why it matters for aging. Brain Imaging Behav 8: 274-283. Available: http://www.ncbi.nlm.nih.gov/pubmed/24008589. Accessed 2014 Jul 14. doi: 10.1007/s11682-013-9253-0 PMID: 24008589
5. Garrett DD, Kovacevic N, McIntosh AR, Grady CL (2013) The modulation of BOLD variability between cognitive states varies by age and processing speed. Cereb Cortex 23: 684-693. Available: http:// www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3823571&tool = pmcentrez&rendertype = abstract . Accessed 2014 Jul 14. doi: 10.1093/cercor/bhs055 PMID: 22419679
6. Deco G, Jirsa V, McIntosh AR, Sporns O, Kötter R (2009) Key role of coupling, delay, and noise in resting brain fluctuations. Proc Natl Acad Sci U S A 106: 10302-10307. Available: http://www. pubmedcentral.nih.gov/articlerender.fcgi?artid = 2690605&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 29. doi: 10.1073/pnas.0901831106 PMID: 19497858
7. Deco G, Jirsa VK, McIntosh AR (2011) Emerging concepts for the dynamical organization of restingstate activity in the brain. Nat Rev Neurosci 12: 43-56. Available: http://www.ncbi.nlm.nih.gov/ pubmed/21170073. Accessed 2014 Jul 11. doi: 10.1038/nrn2961 PMID: 21170073
8. Ghosh A, Rho Y, McIntosh AR, Kötter R, Jirsa VK (2008) Noise during rest enables the exploration of the brain's dynamic repertoire. PLoS Comput Biol 4: e1000196. Available: http://www.pubmedcentral. nih.gov/articlerender.fcgi?artid = 2551736&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 16. doi: 10.1371/journal.pcbi.1000196 PMID: 18846206
9. Raichle ME, MacLeod AM, Snyder AZ, Powers WJ, Gusnard DA, Shulman GL (2001) A default mode of brain function. Proc Natl Acad Sci U S A 98: 676-682. Available: http://www.pubmedcentral.nih.gov/ articlerender.fcgi?artid = 14647&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 14. PMID: 11209064
10. Raichle ME, Snyder AZ (2007) A default mode of brain function: a brief history of an evolving idea. Neuroimage 37: 1083-90; discussion 1097-9. Available: http://www.ncbi.nlm.nih.gov/pubmed/17719799. Accessed 2014 Jul 11. PMID: 17719799
11. Raichle ME (2010) Two views of brain function. Trends Cogn Sci 14: 180-190. Available: http://www. ncbi.nlm.nih.gov/pubmed/20206576. Accessed 2014 Jul 10. doi: 10.1016/j.tics.2010.01.008 PMID: 20206576
12. Faisal AA, Selen LPJ, Wolpert DM (2008) Noise in the nervous system. Nat Rev Neurosci 9: 292-303. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 2631351&tool = pmcentrez&- rendertype = abstract. Accessed 2014 Jul 10. doi: 10.1038/nrn2258 PMID: 18319728
13. Garrett DD, Kovacevic N, McIntosh AR, Grady CL (2010) Blood oxygen level-dependent signal variability is more than just noise. J Neurosci 30: 4914-4921. Available: http://www.ncbi.nlm.nih.gov/pubmed/ 20371811. Accessed 2014 Jul 14. doi: 10.1523/JNEUROSCI.5166-09.2010 PMID: 20371811
14. Garrett DD, Kovacevic N, McIntosh AR, Grady CL (2011) The importance of being variable. J Neurosci 31: 4496-4503. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 3104038&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 14. doi: 10.1523/JNEUROSCI.5641-10.2011 PMID: 21430150
15. Craik F, Salthouse T (2000) Handbook of Aging and Cognition. 2nd ed. Hillsdale, N.J: Lawrence Erlbaum Associates.
16. Birren J, Schaie K, editors (2006) Handbook of the psychology of aging. 6th ed. San Diego, CA.
17. Salthouse TA (2004) Localizing age-related individual differences in a hierarchical structure. Intelligence 32. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 3866028&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 30.
18. Salthouse TA (2005) Relations between cognitive abilities and measures of executive functioning. Neuropsychology 19: 532-545. Available: http://www.ncbi.nlm.nih.gov/pubmed/16060828. Accessed 2014 Jul 30. PMID: 16060828
19. Salthouse TA (2010) Influence of age on practice effects in longitudinal neurocognitive change. Neuropsychology 24: 563-572. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 2933088&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 30. doi: 10.1037/a0019026 PMID: 20804244
20. Salthouse TA, Ferrer-Caja E (2003) What needs to be explained to account for age-related effects on multiple cognitive variables? Psychol Aging 18: 91-110. Available: http://www.ncbi.nlm.nih.gov/ pubmed/12641315. Accessed 2014 Jul 30. PMID: 12641315
21. Kannurpatti SS, Rypma B, Biswal BB (2012) Prediction of Task-Related BOLD fMRI with Amplitude Signatures of Resting-State fMRI. Front Syst Neurosci 6: 7. Available: http://www.pubmedcentral.nih. gov/articlerender.fcgi?artid = 3294272&tool = pmcentrez&rendertype = abstract. Accessed 2014 Nov 3. doi: 10.3389/fnsys.2012.00007 PMID: 22408609
22. Van den Heuvel MP, Sporns O (2011) Rich-club organization of the human connectome. J Neurosci 31: 15775-15786. Available: http://www.ncbi.nlm.nih.gov/pubmed/22049421. Accessed 2014 Jul 10. doi: 10.1523/JNEUROSCI.3539-11.2011 PMID: 22049421
23. Hagmann P, Cammoun L, Gigandet X, Meuli R, Honey CJ, Wedeen VJ, et al. (2008) Mapping the structural core of human cerebral cortex. PLoS Biol 6: e159. Available: http://www.pubmedcentral.nih.gov/ articlerender.fcgi?artid = 2443193&tool = pmcentrez&rendertype = abstract. Accessed 2010 Aug 9. doi: 10.1371/journal.pbio.0060159 PMID: 18597554
24. McIntosh AR, Bookstein FL, Haxby J V, Grady CL (1996) Spatial pattern analysis of functional brain images using partial least squares. Neuroimage 3: 143-157. Available: http://www.ncbi.nlm.nih.gov/ pubmed/9345485. Accessed 2014 Jul 30. PMID: 9345485
25. Haász J, Westlye ET, Fjær S, Espeseth T, Lundervold A, Lundervold AJ (2013) General fluid-type intelligence is related to indices of white matter structure in middle-aged and old adults. Neuroimage 83: 372-383. Available: http://www.ncbi.nlm.nih.gov/pubmed/23791837. Accessed 2014 Jun 23. doi: 10. 1016/j.neuroimage.2013.06.040 PMID: 23791837
26. Burzynska AZ, Nagel IE, Preuschhof C, Gluth S, Bäckman L, Li S-C, et al. (2011) Cortical thickness is linked to executive functioning in adulthood and aging. Hum Brain Mapp. Available: http://www.ncbi. nlm.nih.gov/pubmed/21739526. Accessed 2011 Jul 14.
27. Burzynska AZ, Garrett DD, Preuschhof C, Nagel IE, Li S-C, Bäckman L, et al. (2013) A scaffold for efficiency in the human brain. J Neurosci 33: 17150-17159. Available: http://www.ncbi.nlm.nih.gov/ pubmed/24155318. Accessed 2014 Jul 15. doi: 10.1523/JNEUROSCI.1426-13.2013 PMID: 24155318
28. Jezzard P, Balaban RS (1995) Correction for geometric distortion in echo planar images from B0 field variations. Magn Reson Med 34: 65-73. Available: http://www.ncbi.nlm.nih.gov/pubmed/7674900. Accessed 2014 Jul 17. PMID: 7674900
29. Reese TG, Heid O, Weisskoff RM, Wedeen VJ (2003) Reduction of eddy-current-induced distortion in diffusion MRI using a twice-refocused spin echo. Magn Reson Med 49: 177-182. Available: http:// www.ncbi.nlm.nih.gov/pubmed/12509835. Accessed 2014 Jul 17. PMID: 12509835
30. Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TEJ, Johansen-Berg H, et al. (2004) Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 23 Suppl 1: S208-19. Available: http://www.ncbi.nlm.nih.gov/pubmed/15501092. Accessed 2014 Jul 10. PMID: 15501092
31. Jenkinson M, Bannister P, Brady M, Smith S (2002) Improved optimization for the robust and accurate linear registration and motion correction of brain images. Neuroimage 17: 825-841. Available: http:// www.ncbi.nlm.nih.gov/pubmed/12377157. Accessed 2014 Jul 17. PMID: 12377157
32. Smith SM (2002) Fast robust automated brain extraction. Hum Brain Mapp 17: 143-155. Available: http://www.ncbi.nlm.nih.gov/pubmed/12391568. PMID: 12391568
33. Jenkinson M (2003) Fast, automated, N-dimensional phase-unwrapping algorithm. Magn Reson Med 49: 193-197. Available: http://www.ncbi.nlm.nih.gov/pubmed/12509838. Accessed 2014 Jul 9. PMID: 12509838
34. Greve DN, Fischl B (2009) Accurate and robust brain image alignment using boundary-based registration. Neuroimage 48: 63-72. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 2733527&tool = pmcentrez&rendertype = abstract. Accessed 2010 Jul 16. doi: 10.1016/j.neuroimage. 2009.06.060 PMID: 19573611
35. Beckmann CF, Smith SM (2004) Probabilistic independent component analysis for functional magnetic resonance imaging. IEEE Trans Med Imaging 23: 137-152. Available: http://www.ncbi.nlm.nih.gov/ pubmed/14964560. Accessed 2014 Jul 10. PMID: 14964560
36. Kelly RE, Alexopoulos GS, Wang Z, Gunning FM, Murphy CF, Morimoto SS, et al. (2010) Visual inspection of independent components: defining a procedure for artifact removal from fMRI data. J Neurosci Methods 189: 233-245. Available: http://www.sciencedirect.com/science/article/pii/ S0165027010001627. Accessed 2014 Jul 10. doi: 10.1016/j.jneumeth.2010.03.028 PMID: 20381530
37. Hallquist MN, Hwang K, Luna B (2013) The nuisance of nuisance regression: spectral misspecification in a common approach to resting-state fMRI preprocessing reintroduces noise and obscures functional connectivity. Neuroimage 82: 208-225. Available: http://www.ncbi.nlm.nih.gov/pubmed/23747457. Accessed 2014 Jul 17. doi: 10.1016/j.neuroimage.2013.05.116 PMID: 23747457
38. Birn RM, Diamond JB, Smith MA, Bandettini PA (2006) Separating respiratory-variation-related fluctuations from neuronal-activity-related fluctuations in fMRI. Neuroimage 31: 1536-1548. Available: http:// www.ncbi.nlm.nih.gov/pubmed/16632379. Accessed 2014 Jul 11. PMID: 16632379
39. De Munck JC, Gonçalves SI, Faes TJC, Kuijer JPA, Pouwels PJW, Heethaar RM, et al. (2008) A study of the brain's resting state based on alpha band power, heart rate and fMRI. Neuroimage 42: 112-121. Available: http://www.ncbi.nlm.nih.gov/pubmed/18539049. Accessed 2014 Jul 17. doi: 10.1016/j. neuroimage.2008.04.244 PMID: 18539049
40. Chang C, Glover GH (2009) Effects of model-based physiological noise correction on default mode network anti-correlations and correlations. Neuroimage 47: 1448-1459. Available: http://www. pubmedcentral.nih.gov/articlerender.fcgi?artid = 2995588&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 30. doi: 10.1016/j.neuroimage.2009.05.012 PMID: 19446646
41. Weissenbacher A, Kasess C, Gerstl F, Lanzenberger R, Moser E, Windischberger C (2009) Correlations and anticorrelations in resting-state functional connectivity MRI: a quantitative comparison of preprocessing strategies. Neuroimage 47: 1408-1416. Available: http://www.ncbi.nlm.nih.gov/pubmed/ 19442749. Accessed 2014 Jul 15. doi: 10.1016/j.neuroimage.2009.05.005 PMID: 19442749
42. Krishnan A, Williams LJ, McIntosh AR, Abdi H (2011) Partial Least Squares (PLS) methods for neuroimaging: a tutorial and review. Neuroimage 56: 455-475. Available: http://www.ncbi.nlm.nih.gov/ pubmed/20656037. Accessed 2012 Oct 4. doi: 10.1016/j.neuroimage.2010.07.034 PMID: 20656037
43. McIntosh AR, Lobaugh NJ (2004) Partial least squares analysis of neuroimaging data: applications and advances. Neuroimage 23 Suppl 1: S250-63. Available: http://www.ncbi.nlm.nih.gov/pubmed/ 15501095. Accessed 2012 Oct 4. PMID: 15501095
44. Efron B, Tibshirani R (1993) An introduction to the bootstrap. London: Chapman and Hall.
45. Beaulieu C (2002) The basis of anisotropic water diffusion in the nervous system-a technical review. NMR Biomed 15: 435-455. Available: http://www.ncbi.nlm.nih.gov/pubmed/12489094. Accessed 2014 Jul 10. PMID: 12489094
46. Smith SM, Jenkinson M, Johansen-Berg H, Rueckert D, Nichols TE, Mackay CE, et al. (2006) Tractbased spatial statistics: voxelwise analysis of multi-subject diffusion data. Neuroimage 31: 1487-1505. Available: http://www.ncbi.nlm.nih.gov/pubmed/16624579. Accessed 2014 Jul 12. PMID: 16624579
47. Smith SM, Johansen-Berg H, Jenkinson M, Rueckert D, Nichols TE, Miller KL, et al. (2007) Acquisition and voxelwise analysis of multi-subject diffusion data with tract-based spatial statistics. Nat Protoc 2: 499-503. Available: http://www.ncbi.nlm.nih.gov/pubmed/17406613. PMID: 17406613
48. Rueckert D, Sonoda LI, Hayes C, Hill DL, Leach MO, Hawkes DJ (1999) Nonrigid registration using free-form deformations: application to breast MR images. IEEE Trans Med Imaging 18: 712-721. Available: http://www.ncbi.nlm.nih.gov/pubmed/10534053. Accessed 2014 Jul 14. PMID: 10534053
49. Cattell RB (1963) Theory of fluid and crystallized intelligence: A critical experiment. J Educ Psychol: 1-22.
50. McIntosh AR, Kovacevic N, Lippe S, Garrett D, Grady C, Jirsa V (2010) The development of a noisy brain. Arch Ital Biol 148: 323-337. Available: http://www.ncbi.nlm.nih.gov/pubmed/21175017. Accessed 2014 Jul 30. PMID: 21175017
51. Cavanaugh J, Blanchard-Fields F (2006) Adult development and aging. 5th ed. Belmont, CA: Wadsworth Publishing/Thomson Learning.
52. Li S-C, Lindenberger U, Hommel B, Aschersleben G, Prinz W, Baltes PB (2004) Transformations in the couplings among intellectual abilities and constituent cognitive processes across the life span. Psychol Sci 15: 155-163. Available: http://www.ncbi.nlm.nih.gov/pubmed/15016286. Accessed 2014 Jul 30. PMID: 15016286
53. Buckner RL, Sepulcre J, Talukdar T, Krienen FM, Liu H, Hedden T, et al. (2009) Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease. J Neurosci 29: 1860-1873. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 2750039&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 16. doi: 10.1523/ JNEUROSCI.5062-08.2009 PMID: 19211893
54. Grayson DS, Ray S, Carpenter S, Iyer S, Dias TGC, Stevens T, et al. (2014) Structural and functional rich club organization of the brain in children and adults. PLoS One 9: e88297. Available: http://www. pubmedcentral.nih.gov/articlerender.fcgi?artid = 3915050&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 30. doi: 10.1371/journal.pone.0088297 PMID: 24505468
55. Van den Heuvel MP, Hulshoff Pol HE (2010) Exploring the brain network: a review on resting-state fMRI functional connectivity. Eur Neuropsychopharmacol 20: 519-534. Available: http://www.ncbi.nlm. nih.gov/pubmed/20471808. Accessed 2014 Jul 12. doi: 10.1016/j.euroneuro.2010.03.008 PMID: 20471808
56. Sporns O, Honey CJ, Kötter R (2007) Identification and classification of hubs in brain networks. PLoS One 2: e1049. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 2013941&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 30. PMID: 17940613
57. Colizza V, Flammini A, Serrano MA, Vespignani A (2006) Detecting rich-club ordering in complex networks. Nat Phys 2: 110-115. Available: http://dx.doi.org/10.1038/nphys209. Accessed 2014 Jul 18.
58. Guimerà R, Mossa S, Turtschi A, Amaral LAN (2005) The worldwide air transportation network: Anomalous centrality, community structure, and cities' global roles. Proc Natl Acad Sci U S A 102: 7794-7799. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 1142352&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 13. PMID: 15911778
59. Joyce KE, Laurienti PJ, Burdette JH, Hayasaka S (2010) A new measure of centrality for brain networks. PLoS One 5: e12200. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 2922375&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 19. doi: 10.1371/journal.pone. 0012200 PMID: 20808943
60. Power JD, Schlaggar BL, Lessov-Schlaggar CN, Petersen SE (2013) Evidence for hubs in human functional brain networks. Neuron 79: 798-813. Available: http://www.ncbi.nlm.nih.gov/pubmed/23972601. Accessed 2014 Jul 15. doi: 10.1016/j.neuron.2013.07.035 PMID: 23972601
61. He BJ (2011) Scale-free properties of the functional magnetic resonance imaging signal during rest and task. J Neurosci 31: 13786-13795. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi? artid = 3197021&tool = pmcentrez&rendertype = abstract. Accessed 2014 Sep 7. doi: 10.1523/ JNEUROSCI.2111-11.2011 PMID: 21957241
62. Garrett DD, McIntosh AR, Grady CL (2013) Brain Signal Variability is Parametrically Modifiable. Cereb Cortex. Available: http://www.ncbi.nlm.nih.gov/pubmed/23749875. Accessed 2014 Jul 14.
63. Birn RM (2012) The role of physiological noise in resting-state functional connectivity. Neuroimage 62: 864-870. Available: http://www.ncbi.nlm.nih.gov/pubmed/22245341. Accessed 2014 Jul 10. doi: 10. 1016/j.neuroimage.2012.01.016 PMID: 22245341
64. Murphy K, Birn RM, Bandettini PA (2013) Resting-state fMRI confounds and cleanup. Neuroimage 80: 349-359. Available: http://www.ncbi.nlm.nih.gov/pubmed/23571418. Accessed 2014 Jul 15. doi: 10. 1016/j.neuroimage.2013.04.001 PMID: 23571418
65. Zou Q, Wu CW, Stein EA, Zang Y, Yang Y (2009) Static and dynamic characteristics of cerebral blood flow during the resting state. Neuroimage 48: 515-524. Available: http://www.pubmedcentral.nih.gov/ articlerender.fcgi?artid = 2739419&tool = pmcentrez&rendertype = abstract. Accessed 2014 Oct 31. doi: 10.1016/j.neuroimage.2009.07.006 PMID: 19607928
66. Zhu Z, Johnson NF, Kim C, Gold BT (2013) Reduced Frontal Cortex Efficiency is Associated with Lower White Matter Integrity in Aging. Cereb Cortex: bht212-. Available: http://cercor.oxfordjournals. org/content/early/2013/08/17/cercor.bht212.short. Accessed 2014 Jul 30. doi: 10.1093/cercor/bht212 PMID: 23960206
67. Honey CJ, Sporns O, Cammoun L, Gigandet X, Thiran JP, Meuli R, et al. (2009) Predicting human resting-state functional connectivity from structural connectivity. Proc Natl Acad Sci U S A 106: 2035-2040. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 2634800&tool = pmcentrez& rendertype = abstract. Accessed 2014 Jul 13. doi: 10.1073/pnas.0811168106 PMID: 19188601
68. Van den Heuvel MP, Sporns O (2013) An anatomical substrate for integration among functional networks in human cortex. J Neurosci 33: 14489-14500. Available: http://www.ncbi.nlm.nih.gov/pubmed/ 24005300. Accessed 2014 Jul 9. doi: 10.1523/JNEUROSCI.2128-13.2013 PMID: 24005300
69. Burzynska AZ, Nagel IE, Preuschhof C, Li S-C, Lindenberger U, Bäckman L, et al. (2011) Microstructure of Frontoparietal Connections Predicts Cortical Responsivity and Working Memory Performance. Cereb Cortex. Available: http://www.ncbi.nlm.nih.gov/pubmed/21350048. Accessed 2011 Aug 22.
70. Bartzokis G (2004) Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. Neurobiol Aging 25: 5-18; author reply 49-62. Available: http://www.ncbi.nlm.nih. gov/pubmed/14675724. Accessed 2010 Oct 2. PMID: 14675724
71. Charlton RA, Barrick TR, Markus HS, Morris RG (2013) Verbal working and long-term episodic memory associations with white matter microstructure in normal aging investigated using tract-based spatial statistics. Psychol Aging 28: 768-777. Available: http://www.ncbi.nlm.nih.gov/pubmed/23957226. Accessed 2014 Jul 27. doi: 10.1037/a0032668 PMID: 23957226
72. Borghesani PR, Madhyastha TM, Aylward EH, Reiter MA, Swarny BR, Schaie KW, et al. (2013) The association between higher order abilities, processing speed, and age are variably mediated by white matter integrity during typical aging. Neuropsychologia 51: 1435-1444. Available: http://www.ncbi.nlm. nih.gov/pubmed/23507612. Accessed 2014 Jun 24. doi: 10.1016/j.neuropsychologia.2013.03.005 PMID: 23507612
73. Charlton RA, Barrick TR, Markus HS, Morris RG (2010) The relationship between episodic long-term memory and white matter integrity in normal aging. Neuropsychologia 48: 114-122. Available: http:// www.ncbi.nlm.nih.gov/pubmed/19699215. doi: 10.1016/j.neuropsychologia.2009.08.018 PMID: 19699215
74. Lockhart SN, Mayda AB V, Roach AE, Fletcher E, Carmichael O, Maillard P, et al. (2012) Episodic memory function is associated with multiple measures of white matter integrity in cognitive aging. Front Hum Neurosci 6: 56. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 3305887&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 26. doi: 10.3389/fnhum.2012. 00056 PMID: 22438841
75. Metzler-Baddeley C, Jones DK, Belaroussi B, Aggleton JP, O'SullivanMJ (2011) Frontotemporal connections in episodicmemory and aging: a diffusionMRI tractography study. J Neurosci 31: 13236-13245. Available: http://www.ncbi.nlm.nih.gov/pubmed/21917806. Accessed 2014 Jul 23. doi: 10.1523/ JNEUROSCI.2317-11.2011 PMID: 21917806
76. Salthouse TA (2011) Neuroanatomical substrates of age-related cognitive decline. Psychol Bull 137: 753-784. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid = 3132227&tool = pmcentrez&rendertype = abstract. Accessed 2014 Jul 14. doi: 10.1037/a0023262 PMID: 21463028
77. Raven J (1962) Advanced progressive matrices, sets I and II. London: H.K. Lewis. PMID: 14967850
78. Zachary RA (1986) Shipley Institute of Living Scale. Los Angeles, CA: Western Psychological Services.
79. Ekstrom RB, French JW, Harman HH, Dermen D (1976) Manual for Kit of Factor-referenced Cognitive Tests. Princeton, NJ: Educational Testing Service.
80. Bennett GK, Seashore HG, Wesman AG (1997) Differential Aptitude Test. San Antonio, TX: The Psychological Corporation.
81. Wechsler D (1997) Wechsler Adult Intelligence Scale. Third. San Antonio, TX: The Psychological Corporation.
82. Salthouse TA, Babcock RL (1991) Decomposing Adult Age Differences in Working Memory. Dev Psychol 27: 763-776. Available: http://www.scopus.com/inward/record.url?eid = 2-s2.0-58149206091&partnerID = tZOtx3y1.
83. Wechsler D. (1997) Wechsler Memory Scale. Third. San Antonio, TX: The Psychological Corporation.
84. Salthouse TA, Fristoe N, Rhee SH (1996) How localized are age-related effects on neuropsychological measures? Neuropsychology 10: 272-285. Available: http://www.scopus.com/inward/record.url?eid = 2-s2.0-0029968304&partnerID = tZOtx3y1. Accessed 2014 Jul 30.
85. Woodcock RW, Johnson MB (1990) Woodcock-Johnson Psycho-Educational Battery-Revised. Allen, TX: DLM.
86. Salthouse TA (1993) Speed and knowledge as determinants of adult age differences in verbal tasks. Journals Gerontol
87. Available: http://www.scopus.com/inward/record.url?eid = 2-s2.0-0027389663&partnerID = tZOtx3y1.