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Volumn 236, Issue , 2015, Pages 9-18

AC-93253 triggers the downregulation of melanoma progression markers and the inhibition of melanoma cell proliferation

Author keywords

ABC transporters; AC 93253; Melanoma; Resistance; SIRT

Indexed keywords

ABC TRANSPORTER; AC 93253; CYTOTOXIC AGENT; DOXORUBICIN; PROTEIN INHIBITOR; SIRTUIN 2; TUMOR MARKER; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BENZOTHIAZOLE DERIVATIVE; SIRT2 PROTEIN, HUMAN;

EID: 84929469705     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.04.016     Document Type: Article
Times cited : (14)

References (64)
  • 5
    • 84865764405 scopus 로고    scopus 로고
    • Circumventing melanoma chemoresistance by targeting DNA repair
    • S. Mocellin, L. Bertazza, C. Benna, and P. Pilati Circumventing melanoma chemoresistance by targeting DNA repair Curr. Med. Chem. 19 2012 3893 3899
    • (2012) Curr. Med. Chem. , vol.19 , pp. 3893-3899
    • Mocellin, S.1    Bertazza, L.2    Benna, C.3    Pilati, P.4
  • 7
    • 70350359819 scopus 로고    scopus 로고
    • Chemotherapy and biologic therapies for melanoma: do they work?
    • L.B. Jilaveanu, S.A. Aziz, and H.M. Kluger Chemotherapy and biologic therapies for melanoma: do they work? Clin. Dermatol. 27 2009 614 625
    • (2009) Clin. Dermatol. , vol.27 , pp. 614-625
    • Jilaveanu, L.B.1    Aziz, S.A.2    Kluger, H.M.3
  • 9
    • 84902252466 scopus 로고    scopus 로고
    • New developments in the treatment of metastatic melanoma: immune checkpoint inhibitors and targeted therapies
    • K. Azijli, E. Stelloo, G.J. Peters, and V.D.E. AJ New developments in the treatment of metastatic melanoma: immune checkpoint inhibitors and targeted therapies Anticancer Res. 34 2014 1493 1505
    • (2014) Anticancer Res. , vol.34 , pp. 1493-1505
    • Azijli, K.1    Stelloo, E.2    Peters, G.J.3    Aj, V.D.E.4
  • 15
    • 32944469022 scopus 로고    scopus 로고
    • Well-defined melanoma antigens as progression markers for melanoma: insights into differential expression and host response based on stage
    • F.S. Hodi Well-defined melanoma antigens as progression markers for melanoma: insights into differential expression and host response based on stage Clin. Cancer Res. 12 2006 673 678
    • (2006) Clin. Cancer Res. , vol.12 , pp. 673-678
    • Hodi, F.S.1
  • 16
    • 0030932869 scopus 로고    scopus 로고
    • Cancer-susceptibility genes. Gatekeepers and caretakers
    • K.W. Kinzler, and B. Vogelstein Cancer-susceptibility genes. Gatekeepers and caretakers Nature 386 1997 761 763
    • (1997) Nature , vol.386 , pp. 761-763
    • Kinzler, K.W.1    Vogelstein, B.2
  • 18
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 2000 57 70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 19
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
    • S.B. Baylin, and J.E. Ohm Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat. Rev. Cancer 6 2006 107 116
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 20
    • 33846188098 scopus 로고    scopus 로고
    • MicroRNAs as oncogenes and tumor suppressors
    • B. Zhang, X. Pan, G.P. Cobb, and T.A. Anderson MicroRNAs as oncogenes and tumor suppressors Dev. Biol. 302 2007 1 12
    • (2007) Dev. Biol. , vol.302 , pp. 1-12
    • Zhang, B.1    Pan, X.2    Cobb, G.P.3    Anderson, T.A.4
  • 21
    • 58649094430 scopus 로고    scopus 로고
    • ABCB8 mediates doxorubicin resistance in melanoma cells by protecting the mitochondrial genome
    • A.M. Elliott, and M.A. Al-Hajj ABCB8 mediates doxorubicin resistance in melanoma cells by protecting the mitochondrial genome Mol. Cancer Res. 7 2009 79 87
    • (2009) Mol. Cancer Res. , vol.7 , pp. 79-87
    • Elliott, A.M.1    Al-Hajj, M.A.2
  • 22
    • 34347218991 scopus 로고    scopus 로고
    • In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro
    • C.C. Liang, A.Y. Park, and J.L. Guan In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro Nat. Protoc. 2 2007 329 333
    • (2007) Nat. Protoc. , vol.2 , pp. 329-333
    • Liang, C.C.1    Park, A.Y.2    Guan, J.L.3
  • 23
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • J. Vandesompele, K. De Preter, F. Pattyn, B. Poppe, N. Van Roy, A. De Paepe, and F. Speleman Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Genome Biol 3 2002 (RESEARCH0034)
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6    Speleman, F.7
  • 25
    • 77952948681 scopus 로고    scopus 로고
    • p65 Negatively regulates transcription of the cyclin E gene
    • V.C. Janbandhu, A.K. Singh, A. Mukherji, and V. Kumar p65 Negatively regulates transcription of the cyclin E gene J. Biol. Chem. 285 2010 17453 17464
    • (2010) J. Biol. Chem. , vol.285 , pp. 17453-17464
    • Janbandhu, V.C.1    Singh, A.K.2    Mukherji, A.3    Kumar, V.4
  • 26
    • 4544343758 scopus 로고    scopus 로고
    • Histone acetylation regulates p21WAF1 expression in human colon cancer cell lines
    • Y.X. Chen, J.Y. Fang, H.Y. Zhu, R. Lu, Z.H. Cheng, and D.K. Qiu Histone acetylation regulates p21WAF1 expression in human colon cancer cell lines World J. Gastroenterol. 10 2004 2643 2646
    • (2004) World J. Gastroenterol. , vol.10 , pp. 2643-2646
    • Chen, Y.X.1    Fang, J.Y.2    Zhu, H.Y.3    Lu, R.4    Cheng, Z.H.5    Qiu, D.K.6
  • 28
    • 0344010620 scopus 로고    scopus 로고
    • Real-time PCR analysis of the apoptosis related genes in ATRA treated APL t(15;17) patients
    • H. Savli, S. Sirma, B. Nagy, M. Aktan, G. Dincol, and U. Ozbek Real-time PCR analysis of the apoptosis related genes in ATRA treated APL t(15;17) patients Exp. Mol. Med. 35 2003 454 459
    • (2003) Exp. Mol. Med. , vol.35 , pp. 454-459
    • Savli, H.1    Sirma, S.2    Nagy, B.3    Aktan, M.4    Dincol, G.5    Ozbek, U.6
  • 29
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for general users and for biologist programmers
    • S. Rozen, and H. Skaletsky Primer3 on the WWW for general users and for biologist programmers Methods Mol. Biol. 132 2000 365 386
    • (2000) Methods Mol. Biol. , vol.132 , pp. 365-386
    • Rozen, S.1    Skaletsky, H.2
  • 30
    • 79952229559 scopus 로고    scopus 로고
    • Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8
    • I. Sachrajda, and M. Ratajewski Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8 Mol. Genet. Genomics 285 2011 57 65
    • (2011) Mol. Genet. Genomics , vol.285 , pp. 57-65
    • Sachrajda, I.1    Ratajewski, M.2
  • 31
    • 70350100345 scopus 로고    scopus 로고
    • Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma
    • K.G. Chen, J.C. Valencia, J.P. Gillet, V.J. Hearing, and M.M. Gottesman Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma Pigment Cell Melanoma Res. 22 2009 740 749
    • (2009) Pigment Cell Melanoma Res. , vol.22 , pp. 740-749
    • Chen, K.G.1    Valencia, J.C.2    Gillet, J.P.3    Hearing, V.J.4    Gottesman, M.M.5
  • 34
    • 84859447698 scopus 로고    scopus 로고
    • The role of sirtuin 2 activation by nicotinamide phosphoribosyltransferase in the aberrant proliferation and survival of myeloid leukemia cells
    • L. Dan, O. Klimenkova, M. Klimiankou, J.H. Klusman, M.M. van den Heuvel-Eibrink, D. Reinhardt, K. Welte, and J. Skokowa The role of sirtuin 2 activation by nicotinamide phosphoribosyltransferase in the aberrant proliferation and survival of myeloid leukemia cells Haematologica 97 2012 551 559
    • (2012) Haematologica , vol.97 , pp. 551-559
    • Dan, L.1    Klimenkova, O.2    Klimiankou, M.3    Klusman, J.H.4    Van Den Heuvel-Eibrink, M.M.5    Reinhardt, D.6    Welte, K.7    Skokowa, J.8
  • 35
    • 84862702751 scopus 로고    scopus 로고
    • An intron-retaining splice variant of human cyclin A2, expressed in adult differentiated tissues, induces a G1/S cell cycle arrest in vitro
    • A. Honda, Y. Valogne, M. Bou Nader, C. Brechot, and J. Faivre An intron-retaining splice variant of human cyclin A2, expressed in adult differentiated tissues, induces a G1/S cell cycle arrest in vitro PLoS One 7 2012 e39249
    • (2012) PLoS One , vol.7
    • Honda, A.1    Valogne, Y.2    Bou Nader, M.3    Brechot, C.4    Faivre, J.5
  • 41
    • 0024438925 scopus 로고
    • Analysis of ras oncogenes in malignant melanoma and precursor lesions: correlation of point mutations with differentiation phenotype
    • A.P. Albino, D.M. Nanus, I.R. Mentle, C. Cordon-Cardo, N.S. McNutt, J. Bressler, and M. Andreeff Analysis of ras oncogenes in malignant melanoma and precursor lesions: correlation of point mutations with differentiation phenotype Oncogene 4 1989 1363 1374
    • (1989) Oncogene , vol.4 , pp. 1363-1374
    • Albino, A.P.1    Nanus, D.M.2    Mentle, I.R.3    Cordon-Cardo, C.4    McNutt, N.S.5    Bressler, J.6    Andreeff, M.7
  • 42
    • 0348223934 scopus 로고    scopus 로고
    • NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression
    • K. Omholt, A. Platz, L. Kanter, U. Ringborg, and J. Hansson NRAS and BRAF mutations arise early during melanoma pathogenesis and are preserved throughout tumor progression Clin. Cancer Res. 9 2003 6483 6488
    • (2003) Clin. Cancer Res. , vol.9 , pp. 6483-6488
    • Omholt, K.1    Platz, A.2    Kanter, L.3    Ringborg, U.4    Hansson, J.5
  • 43
    • 0037442752 scopus 로고    scopus 로고
    • Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation
    • K. Satyamoorthy, G. Li, M.R. Gerrero, M.S. Brose, P. Volpe, B.L. Weber, P. Van Belle, D.E. Elder, and M. Herlyn Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation Cancer Res. 63 2003 756 759
    • (2003) Cancer Res. , vol.63 , pp. 756-759
    • Satyamoorthy, K.1    Li, G.2    Gerrero, M.R.3    Brose, M.S.4    Volpe, P.5    Weber, B.L.6    Van Belle, P.7    Elder, D.E.8    Herlyn, M.9
  • 45
    • 0033397882 scopus 로고    scopus 로고
    • Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma
    • D. Grossman, J.M. McNiff, F. Li, and D.C. Altieri Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma J. Invest. Dermatol. 113 1999 1076 1081
    • (1999) J. Invest. Dermatol. , vol.113 , pp. 1076-1081
    • Grossman, D.1    McNiff, J.M.2    Li, F.3    Altieri, D.C.4
  • 46
    • 28044440925 scopus 로고    scopus 로고
    • Survivin expression by metastatic melanoma predicts poor disease outcome in patients receiving adjuvant polyvalent vaccine
    • H. Takeuchi, D.L. Morton, D. Elashoff, and D.S. Hoon Survivin expression by metastatic melanoma predicts poor disease outcome in patients receiving adjuvant polyvalent vaccine Int. J. Cancer 117 2005 1032 1038
    • (2005) Int. J. Cancer , vol.117 , pp. 1032-1038
    • Takeuchi, H.1    Morton, D.L.2    Elashoff, D.3    Hoon, D.S.4
  • 48
    • 4344660599 scopus 로고    scopus 로고
    • Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis
    • M. Chawla-Sarkar, S.I. Bae, F.J. Reu, B.S. Jacobs, D.J. Lindner, and E.C. Borden Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis Cell Death Differ. 11 2004 915 923
    • (2004) Cell Death Differ. , vol.11 , pp. 915-923
    • Chawla-Sarkar, M.1    Bae, S.I.2    Reu, F.J.3    Jacobs, B.S.4    Lindner, D.J.5    Borden, E.C.6
  • 50
    • 39149122568 scopus 로고    scopus 로고
    • Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis
    • B.J. North, and E. Verdin Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis PLoS One 2 2007 e784
    • (2007) PLoS One , vol.2 , pp. e784
    • North, B.J.1    Verdin, E.2
  • 52
    • 34247570492 scopus 로고    scopus 로고
    • Strong expression of a longevity-related protein, SIRT1, Bowen's disease
    • Y. Hida, Y. Kubo, K. Murao, and S. Arase Strong expression of a longevity-related protein, SIRT1, Bowen's disease Arch. Dermatol. Res. 299 2007 103 106
    • (2007) Arch. Dermatol. Res. , vol.299 , pp. 103-106
    • Hida, Y.1    Kubo, Y.2    Murao, K.3    Arase, S.4
  • 53
    • 84898950030 scopus 로고    scopus 로고
    • Novel downstream molecular targets of SIRT1 in melanoma: a quantitative proteomics approach
    • C.K. Singh, J. George, M. Nihal, G. Sabat, R. Kumar, and N. Ahmad Novel downstream molecular targets of SIRT1 in melanoma: a quantitative proteomics approach Oncotarget 5 2014 1987 1999
    • (2014) Oncotarget , vol.5 , pp. 1987-1999
    • Singh, C.K.1    George, J.2    Nihal, M.3    Sabat, G.4    Kumar, R.5    Ahmad, N.6
  • 54
    • 84908404597 scopus 로고    scopus 로고
    • SIRT1 deacetylase is overexpressed in human melanoma and its small molecule inhibition imparts anti-proliferative response via p53 activation
    • M.J. Wilking, C. Singh, M. Nihal, W. Zhong, and N. Ahmad SIRT1 deacetylase is overexpressed in human melanoma and its small molecule inhibition imparts anti-proliferative response via p53 activation Arch. Biochem. Biophys. 563 2014 94 100
    • (2014) Arch. Biochem. Biophys. , vol.563 , pp. 94-100
    • Wilking, M.J.1    Singh, C.2    Nihal, M.3    Zhong, W.4    Ahmad, N.5
  • 57
    • 84873108957 scopus 로고    scopus 로고
    • Imatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-kappaB and HSP27/p38/AKT pathways and by inhibiting ABCB1
    • J.T. Sims, S.S. Ganguly, H. Bennett, J.W. Friend, J. Tepe, and R. Plattner Imatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-kappaB and HSP27/p38/AKT pathways and by inhibiting ABCB1 PLoS One 8 2013 e55509
    • (2013) PLoS One , vol.8
    • Sims, J.T.1    Ganguly, S.S.2    Bennett, H.3    Friend, J.W.4    Tepe, J.5    Plattner, R.6
  • 58
    • 0037405043 scopus 로고    scopus 로고
    • Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle
    • S.C. Dryden, F.A. Nahhas, J.E. Nowak, A.S. Goustin, and M.A. Tainsky Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle Mol. Cell. Biol. 23 2003 3173 3185
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 3173-3185
    • Dryden, S.C.1    Nahhas, F.A.2    Nowak, J.E.3    Goustin, A.S.4    Tainsky, M.A.5
  • 59
    • 34248151365 scopus 로고    scopus 로고
    • The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation
    • T. Inoue, M. Hiratsuka, M. Osaki, and M. Oshimura The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation Cell Cycle 6 2007 1011 1018
    • (2007) Cell Cycle , vol.6 , pp. 1011-1018
    • Inoue, T.1    Hiratsuka, M.2    Osaki, M.3    Oshimura, M.4
  • 60
    • 78650638268 scopus 로고    scopus 로고
    • SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis
    • Y. Li, H. Matsumori, Y. Nakayama, M. Osaki, H. Kojima, A. Kurimasa, H. Ito, S. Mori, M. Katoh, M. Oshimura, and T. Inoue SIRT2 down-regulation in HeLa can induce p53 accumulation via p38 MAPK activation-dependent p300 decrease, eventually leading to apoptosis Genes Cells 16 2011 34 45
    • (2011) Genes Cells , vol.16 , pp. 34-45
    • Li, Y.1    Matsumori, H.2    Nakayama, Y.3    Osaki, M.4    Kojima, H.5    Kurimasa, A.6    Ito, H.7    Mori, S.8    Katoh, M.9    Oshimura, M.10    Inoue, T.11
  • 61
    • 84863033018 scopus 로고    scopus 로고
    • HDAC6 and SIRT2 promote bladder cancer cell migration and invasion by targeting cortactin
    • Q. Zuo, W. Wu, X. Li, L. Zhao, and W. Chen HDAC6 and SIRT2 promote bladder cancer cell migration and invasion by targeting cortactin Oncol. Rep. 27 2012 819 824
    • (2012) Oncol. Rep. , vol.27 , pp. 819-824
    • Zuo, Q.1    Wu, W.2    Li, X.3    Zhao, L.4    Chen, W.5
  • 62
    • 79959906869 scopus 로고    scopus 로고
    • Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase
    • W. Jiang, S. Wang, M. Xiao, Y. Lin, L. Zhou, Q. Lei, Y. Xiong, K.L. Guan, and S. Zhao Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase Mol. Cell 43 2011 33 44
    • (2011) Mol. Cell , vol.43 , pp. 33-44
    • Jiang, W.1    Wang, S.2    Xiao, M.3    Lin, Y.4    Zhou, L.5    Lei, Q.6    Xiong, Y.7    Guan, K.L.8    Zhao, S.9


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