Risk factors for hospitalization due to community-acquired sepsis - A population-based case-control study

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Henriksen, Daniel Pilsgaard ^a   Pottegård, Anton ^b   Laursen, Christian B ^a   Jensen, Thøger Gorm ^a   Hallas, Jesper ^a,b   Pedersen, Court ^a   Lassen, Annmarie Touborg ^a  

^a ODENSE UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ALCOHOLISM; ARTICLE; CARDIOVASCULAR DISEASE; COMMUNITY ACQUIRED INFECTION; COMMUNITY ACQUIRED SEPSIS; COMORBIDITY; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE SEVERITY; FEMALE; GASTROINTESTINAL DISEASE; HIGH RISK POPULATION; HOSPITALIZATION; HUMAN; IMMUNE DEFICIENCY; KIDNEY DISEASE; MAJOR CLINICAL STUDY; MALE; NEOPLASM; NEUROLOGIC DISEASE; POPULATION BASED CASE CONTROL STUDY; PSYCHOSIS; RESPIRATORY TRACT DISEASE; RISK FACTOR; SEPSIS; SEPTIC SHOCK; SEX DIFFERENCE; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; AGE; CARDIOVASCULAR DISEASES; CASE CONTROL STUDY; GASTROINTESTINAL DISEASES; INTENSIVE CARE UNIT; MIDDLE AGED; MORTALITY; PATHOLOGY; PSYCHOTIC DISORDERS; SEVERITY OF ILLNESS INDEX; STATISTICAL MODEL; SURVIVAL ANALYSIS; VERY ELDERLY;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CARDIOVASCULAR DISEASES; CASE-CONTROL STUDIES; COMMUNITY-ACQUIRED INFECTIONS; COMORBIDITY; DIABETES MELLITUS; FEMALE; GASTROINTESTINAL DISEASES; HOSPITALIZATION; HUMANS; INTENSIVE CARE UNITS; LOGISTIC MODELS; MALE; MIDDLE AGED; PSYCHOTIC DISORDERS; RISK FACTORS; SEPSIS; SEVERITY OF ILLNESS INDEX; SEX FACTORS; SURVIVAL ANALYSIS;

EID: 84929466777     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124838     Document Type: Article

References (36)

1. Angus DC, van der Poll T. Severe sepsis and septic shock. N Engl J Med. 2013; 369: 840-51. doi: 10.1056/NEJMra1208623 PMID: 23984731
2. Wang HE, Shapiro NI, Angus DC, Yealy DM. National estimates of severe sepsis in United States emergency departments. Crit Care Med. 2007; 35: 1928-36. doi: 10.1097/01.CCM.0000277043.85378.C1 PMID: 17581480
3. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001; 345: 1368-77. doi: 10.1056/NEJMoa010307 PMID: 11794169
4. Kumar A, Roberts D, Wood KE, Light B, Parrillo JE, Sharma S, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006; 34: 1589-96. doi: 10.1097/01.CCM.0000217961.75225.E9 PMID: 16625125
5. Wang HE, Shapiro NI, Griffin R, Safford MM, Judd S, Howard G. Chronic medical conditions and risk of sepsis. PLoS One. 2012; 7: e48307. doi: 10.1371/ journal.pone.0048307 PMID: 23118977
6. Wang HE, Gamboa C, Warnock DG, Muntner P. Chronic kidney disease and risk of death from infection. Am J Nephrol. 2011; 34: 330-6. doi: 10.1159/000330673 PMID: 21860228
7. Storgaard M, Hallas J, Gahrn-Hansen B, Pedersen SS, Pedersen C, Lassen AT. Short- and long-term mortality in patients with community-acquired severe sepsis and septic shock. Scand J Infect Dis. 2013; 1-7. doi: 10.3109/00365548.2013.786836
8. Moss M. Epidemiology of sepsis: race, sex, and chronic alcohol abuse. Clin Infect Dis. 2005; 41 Suppl 7: S490-7. doi: 10.1086/432003 PMID: 16237652
9. Esper AM, Moss M, Lewis C a, Nisbet R, Mannino DM, Martin GS. The role of infection and comorbidity: Factors that influence disparities in sepsis. Crit Care Med. 2006; 34: 2576-82. doi: 10.1097/01.CCM.0000239114.50519.0E PMID: 16915108
10. Ginde A a, Moss M, Shapiro NI, Schwartz RS. Impact of older age and nursing home residence on clinical outcomes of US emergency department visits for severe sepsis. J Crit Care. Elsevier Inc.; 2013; 28: 606-11. doi: 10.1016/j.jcrc.2013.03.018 PMID: 23683561
11. Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001; 29: 1303-10. Available: http://www.ncbi.nlm.nih.gov/pubmed/11445675 PMID: 11445675
12. Sundararajan V, Macisaac CM, Presneill JJ, Cade JF, Visvanathan K. Epidemiology of sepsis in Victoria, Australia. Crit Care Med. 2005; 33: 71-80. doi: 10.1097/01.CCM.0000150027.98160.80 PMID: 15644651
13. O'Brien JM, Lu B, Ali NA, Martin GS, Aberegg SK, Marsh CB, et al. Alcohol dependence is independently associated with sepsis, septic shock, and hospital mortality among adult intensive care unit patients. Crit Care Med. 2007; 35: 345-50. doi: 10.1097/01.CCM.0000254340.91644.B2 PMID: 17205003
14. Poutsiaka DD, Davidson LE, Kahn KL, Bates DW, Snydman DR, Hibberd PL. Risk factors for death after sepsis in patients immunosuppressed before the onset of sepsis. Scand J Infect Dis. 2009; 41: 469-79. doi: 10.1080/00365540902962756 PMID: 19452348
15. Trifirò G, Gambassi G, Sen EF, Caputi AP, Bagnardi V, Brea J, et al. Association of community-acquired pneumonia with antipsychotic drug use in elderly patients: a nested case-control study. Ann Intern Med. 2010; 152: 418-25, W139-40. doi: 10.7326/0003-4819-152-7-201004060-00006 PMID: 20368647
16. Frank L. Epidemiology. When an entire country is a cohort. Science. 2000; 287: 2398-9. doi: 10.1126/science.287.5462.2398 PMID: 10766613
17. Henriksen DP, Laursen CB, Jensen TG, Hallas J, Pedersen C, Lassen AT. Incidence rate of community-acquired sepsis among hospitalized acute medical patients-a population-based survey∗. Crit Care Med. 2015; 43: 13-21. doi: 10.1097/CCM.0000000000000611 PMID: 25251760
18. Horan TC, Andrus M, Dudeck M a. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control. 2008; 36: 309-32. doi: 10.1016/j.ajic.2008.03.002 PMID: 18538699
19. Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977; 33: 159-74. Available: http://www.ncbi.nlm.nih.gov/pubmed/843571 PMID: 843571
20. Pedersen CB. The Danish Civil Registration System. Scand J Public Health. 2011; 39: 22-5. doi: 10.1177/1403494810387965 PMID: 21775345
21. Lynge E, Sandegaard JL, Rebolj M. The Danish National Patient Register. Scand J Public Health. 2011; 39: 30-3. doi: 10.1177/1403494811401482 PMID: 21775347
22. Hallas J. Conducting pharmacoepidemiologic research in Denmark. Pharmacoepidemiol Drug Saf. 2001; 10: 619-23. doi: 10.1002/pds.638 PMID: 11980250
23. Gjerstorff ML. The Danish Cancer Registry. Scand J Public Health. 2011; 39: 42-5. doi: 10.1177/1403494810393562 PMID: 21775350
24. Bone R, Balk R, Cerra F, Dellinger R, Fein a., Knaus W, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest. 1992; 101: 1644-1655. doi: 10.1378/chest.101.6.1644 PMID: 1303622
25. Royston P, Ambler G, Sauerbrei W. The use of fractional polynomials to model continuous risk variables in epidemiology. Int J Epidemiol. 1999; 28: 964-74. Available: http://www.ncbi.nlm.nih.gov/pubmed/10597998 PMID: 10597998
26. Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med. 2003; 348: 1546-54. doi: 10.1056/NEJMoa022139 PMID: 12700374
27. Martin GS, Mannino DM, Moss M. The effect of age on the development and outcome of adult sepsis∗. Crit Care Med. 2006; 34: 15-21. doi: 10.1097/01.CCM.0000194535.82812.BA PMID: 16374151
28. Mayr FB, Yende S, Linde-Zwirble WT, Peck-Palmer OM, Barnato AE, Weissfeld LA, et al. Infection rate and acute organ dysfunction risk as explanations for racial differences in severe sepsis. JAMA. 2010; 303: 2495-503. doi: 10.1001/jama.2010.851 PMID: 20571016
29. Strehlow MC, Emond SD, Shapiro NI, Pelletier AJ, Camargo C a. National study of emergency department visits for sepsis, 1992 to 2001. Ann Emerg Med. 2006; 48: 326-31, 331.e1-3. doi: 10.1016/j.annemergmed.2006.05.003 PMID: 16934654
30. Thygesen SK, Christiansen CF, Christensen S, Lash TL, Sørensen HT. The predictive value of ICD-10 diagnostic coding used to assess Charlson comorbidity index conditions in the population-based Danish National Registry of Patients. BMC Med Res Methodol. BioMed Central Ltd; 2011; 11: 83. doi: 10.1186/1471-2288-11-83 PMID: 21619668
31. Thomsen RW, Lange P, Hellquist B, Frausing E, Bartels PD, Krog BR, et al. Validity and underrecording of diagnosis of COPD in the Danish National Patient Registry. Respir Med. Elsevier Ltd; 2011; 105: 1063-8. doi: 10.1016/j.rmed.2011.01.012 PMID: 21320769
32. Harrington RD, Hooton TM. Urinary tract infection risk factors and gender. J Gend Specif Med. 2000; 3: 27-34. Available: http://www.ncbi.nlm.nih.gov/pubmed/11253265 PMID: 11253265
33. States U. Ten great public health achievements - United States, 1900-1999. MMWR Morb Mortal Wkly Rep. 1999; 48: 241-3. Available: http://www.ncbi.nlm.nih.gov/pubmed/10227303 PMID: 10220250
34. Fielding JE. Public health in the twentieth century: advances and challenges. Annu Rev Public Health. 1999; 20: xiii-xxx. doi: 10.1146/annurev.publhealth.20.1.0 PMID: 10352845
35. Seymour CW, Iwashyna TJ, Cooke CR, Hough CL, Martin GS. Marital status and the epidemiology and outcomes of sepsis. Chest. 2010; 137: 1289-96. doi: 10.1378/chest.09-2661 PMID: 20173054
36. Soto GJ, Martin GS, Gong MN. Healthcare disparities in critical illness. Crit Care Med. 2013; 41: 2784-93. doi: 10.1097/CCM.0b013e3182a84a43 PMID: 24121467