Hollow gold nanoparticles as biocompatible radiosensitizer: An in vitro proof of concept study

Journal of Nano Research

Volumn 32, Issue , 2015, Pages 106-112

  Huang, Chienwen ^a   Kearney, Vasant ^a   Moeendarbari, Sina ^b   Jiang, Ruiqian ^b   Christensen, Preston ^a   Tekade, Rakesh ^a   Sun, Xiankai ^a   Mao, Weihua ^a   Hao, Yaowu ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b University of Texas at Arlington   (United States)

Author keywords

Gold nanoparticles; Hollow nanoparticles; Radiation dose enhancement; Radiation therapy

Indexed keywords

BIOCOMPATIBILITY; CELL CULTURE; CELLS; CYTOLOGY; DISEASES; FIBER OPTIC SENSORS; METAL NANOPARTICLES; NANOPARTICLES; RADIATION DAMAGE; RADIOTHERAPY; TUMORS;

CLINICAL SETTINGS; DOSE ENHANCEMENTS; ENHANCED PERMEABILITY AND RETENTION EFFECT; GOLD NANOPARTICLES; HOLLOW NANOPARTICLES; INTRATUMORAL INJECTION; NANOPARTICLE CONCENTRATIONS; POLYCRYSTALLINE SHELLS;

GOLD;

EID: 84929457960     PISSN: 16625250     EISSN: 16619897     Source Type: Journal    
DOI: 10.4028/www.scientific.net/JNanoR.32.106     Document Type: Article

References (31)

1. Connell, P.P., and Hellman, S., Advances in Radiotherapy and Implications for the Next Century: A Historical Perspective, Cancer Res. 69 (2009) 383-392.
2. Eriksson, D., and Stigbrand, T., Radiation-induced cell death mechanisms, Tumor Biology. 31 (2010) 363-372.
3. Bhide, S.A., and Nutting, C.M., Recent advances in radiotherapy, Bmc Medicine. 8 (2010).
4. Berdis, A.J., Current and emerging strategies to increase the efficacy of ionizing radiation in the treatment of cancer, Expert Opinion on Drug Discovery. 9 (2014) 167-181.
5. Dykman, L., and Khlebtsov, N., Gold nanoparticles in biomedical applications: Recent advances and perspectives, Chem Soc Rev. 41 (2012) 2256-2282.
6. Boisselier, E., and Astruc, D., Gold nanoparticles in nanomedicine: Preparations, imaging, diagnostics, therapies and toxicity, Chem Soc Rev. 38 (2009) 1759-1782.
7. Ghosh, P., Han, G., De, M., Kim, C.K., and Rotello, V.M., Gold nanoparticles in delivery applications, Advanced Drug Delivery Reviews. 60 (2008) 1307-1315.
8. Zhang, X.J., Xing, J.Z., Chen, J., Ko, L., Amanie, J., Gulavita, S., Pervez, N., Yee, D., Moore, R., and Roa, W., Enhanced radiation sensitivity in prostate cancer by gold-nanoparticles, Clin Invest Med. 31 (2008) E160-E167.
9. Hainfeld, J.F., Dilmanian, F.A., Slatkin, D.N., and Smilowitz, H.M., Radiotherapy enhancement with gold nanoparticles, Journal of Pharmacy and Pharmacology. 60 (2008) 977-985.
10. Hainfeld, J.F., Dilmanian, F.A., Zhong, Z., Slatkin, D.N., Kalef-Ezra, J.A., and Smilowitz, H.M., Gold nanoparticles enhance the radiation therapy of a murine squamous cell carcinoma, Physics in Medicine and Biology. 55 (2010) 3045-3059.
11. Chithrani, D.B., Jelveh, S., Jalali, F., van Prooijen, M., Allen, C., Bristow, R.G., Hill, R.P., and Jaffray, D.A., Gold Nanoparticles as Radiation Sensitizers in Cancer Therapy, Radiat Res. 173 (2010) 719-728.
12. McMahon, S.J., Hyland, W.B., Muir, M.F., Coulter, J.A., Jain, S., Butterworth, K.T., Schettino, G., Dickson, G.R., Hounsell, A.R., O'Sullivan, J.M., Prise, K.M., Hirst, D.G., and Currell, F.J., Nanodosimetric effects of gold nanoparticles in megavoltage radiation therapy, Radiotherapy and Oncology. 100 (2011) 412-416.
13. Xiao, F.X., Zheng, Y., Cloutier, P., He, Y.H., Hunting, D., and Sanche, L., On the role of low-energy electrons in the radiosensitization of DNA by gold nanoparticles, Nanotechnology. 22 (2011).
14. Billotey, C., Nanoparticles in radiotherapy, Biofutur (2012) 32-34.
15. Butterworth, K.T., McMahon, S.J., Currell, F.J., and Prise, K.M., Physical basis and biological mechanisms of gold nanoparticle radiosensitization, Nanoscale. 4 (2012) 4830-4838.
16. Chattopadhyay, N., Cai, Z.L., Kwon, Y.L., Lechtman, E., Pignol, J.P., and Reilly, R.M., Molecularly targeted gold nanoparticles enhance the radiation response of breast cancer cells and tumor xenografts to X-radiation, Breast Cancer Research and Treatment. 137 (2013) 81-91.
17. Coulter, J.A., Hyland, W.B., Nicol, J., and Currell, F.J., Radiosensitising Nanoparticles as Novel Cancer Therapeutics - Pipe Dream or Realistic Prospect?, Clinical Oncology. 25 (2013) 593-603.
18. Jeremic, B., Aguerri, A.R., and Filipovic, N., Radiosensitization by gold nanoparticles, Clinical & Translational Oncology. 15 (2013) 593-601.
19. Pottier, A., Borghi, E., and Levy, L., New Use of Metals as Nanosized Radioenhancers, Anticancer Research. 34 (2014) 443-453.
20. Douglass, M., Bezak, E., and Penfold, S., Monte Carlo investigation of the increased radiation deposition due to gold nanoparticles using kilovoltage and megavoltage photons in a 3D randomized cell model, Medical Physics. 40 (2013).
21. Cai, Z.L., Pignol, J.P., Chattopadhyay, N., Kwon, Y.L., Lechtman, E., and Reilly, R.M., Investigation of the effects of cell model and subcellular location of gold nanoparticles on nuclear dose enhancement factors using Monte Carlo simulation, Medical Physics. 40 (2013).
22. Ghorbani, M., Bakhshabadi, M., Golshan, A., and Knaup, C., Dose enhancement by various nanoparticles in prostate brachytherapy, Australasian Physical & Engineering Sciences in Medicine. 36 (2013) 431-440.
23. Lechtman, E., Mashouf, S., Chattopadhyay, N., Keller, B.M., Lai, P., Cai, Z., Reilly, R.M., and Pignol, J.P., A Monte Carlo-based model of gold nanoparticle radiosensitization accounting for increased radiobiological effectiveness, Physics in Medicine and Biology. 58 (2013) 3075-3087.
24. Cheng, N.N., Starkewolf, Z., Davidson, R.A., Sharmah, A., Lee, C., Lien, J., and Guo, T., Chemical Enhancement by Nanomaterials under X-ray Irradiation, J Am Chem Soc. 134 (2012) 1950-1953.
25. Huang, C.W., Jiang, J.C., Lu, M.Y., Sun, L., Meletis, E.I., and Hao, Y.W., Capturing Electrochemically Evolved Nanobubbles by Electroless Deposition. A Facile Route to the Synthesis of Hollow Nanoparticles, Nano Lett. 9 (2009) 4297-4301.
26. Khlebtsov, N., and Dykman, L., Biodistribution and toxicity of engineered gold nanoparticles: A review of in vitro and in vivo studies, Chem Soc Rev. 40 (2011) 1647-1671.
27. Franken, N.A.P., Rodermond, H.M., Stap, J., Haveman, J., and Bree, C.v., Clonogenic assay of cells in vitro, Nature Protocols. 1 (2006) 2315-2319.
28. Gao, H.J., Shi, W.D., and Freund, L.B., Mechanics of receptor-mediated endocytosis, Proc Natl Acad Sci U S A. 102 (2005) 9469-9474.
29. Rahman, W.N., Bishara, N., Ackerly, T., He, C.F., Jackson, P., Wong, C., Davidson, R., and Geso, M., Enhancement of radiation effects by gold nanoparticles for superficial radiation therapy, Nanomedicine-Nanotechnology Biology and Medicine. 5 (2009) 136-142.
30. Chang, M.-Y., Shiau, A.-L., Chen, Y.-H., Chang, C.-J., Chen, H.H.W., and Wu, C.-L., Increased apoptotic potential and dose-enhancing effect of gold nanoparticles in combination with single-dose clinical electron beams on tumor-bearing mice, Cancer Science. 99 (2008) 1479-1484.
31. Jain, S., Coulter, J.A., Hounsell, A.R., Butterworth, K.T., McMahon, S.J., Hyland, W.B., Muir, M.F., Dickson, G.R., Prise, K.M., Currell, F.J., O'Sullivan, J.M., and Hirst, D.G., Cell-specific Radiosensitization by Gold Nanoparticles at Megavoltage Radiation Energies, International Journal of Radiation Oncology Biology Physics. 79 (2011) 531-539.