Investigation of the effects of cell model and subcellular location of gold nanoparticles on nuclear dose enhancement factors using Monte Carlo simulation

Medical Physics

Volumn 40, Issue 11, 2013, Pages

  Cai, Zhongli ^a   Pignol, Jean Philippe ^b   Chattopadhyay, Niladri ^a   Kwon, Yongkyu Luke ^a   Lechtman, Eli ^b   Reilly, Raymond M ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

cell nucleus; dose enhancement; gold nanoparticles; Monte Carlo simulation; radiosensitization; x rays

Indexed keywords

CELL MEMBRANES; DISEASES; ELECTRON TRANSPORT PROPERTIES; FIBER OPTIC SENSORS; GOLD NANOPARTICLES; LOCATION; METAL NANOPARTICLES; MONOLAYERS; MONTE CARLO METHODS; PHOTONS; RADIOTHERAPY; TISSUE; X RAYS;

CELL NUCLEUS; DOSE ENHANCEMENT FACTORS; DOSE ENHANCEMENTS; EXPERIMENTAL CONDITIONS; HUMAN BREAST CANCER CELLS; MONTE CARLO N PARTICLES; RADIATION ENHANCEMENT; RADIO-SENSITIZATION;

CYTOLOGY;

GOLD NANOPARTICLE; IODINE 125; PALLADIUM 103; GOLD; METAL NANOPARTICLE; PALLADIUM; RADIOACTIVE IODINE; RADIOISOTOPE;

ARTICLE; BRACHYTHERAPY; BREAST CANCER; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CELL NUCLEUS; CELL SURFACE; CELLULAR DISTRIBUTION; COMPUTER MODEL; CYTOPLASM; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; MONTE CARLO METHOD; RADIATION DOSE; RADIOISOTOPE THERAPY; X RAY; X RAY BEAM LIMITING DEVICE; BREAST TUMOR; CHEMISTRY; ELECTRON; FEMALE; IMAGE PROCESSING; METHODOLOGY; PATHOLOGY; PHOTON; SCINTISCANNING;

BRACHYTHERAPY; BREAST NEOPLASMS; CELL NUCLEUS; CYTOPLASM; ELECTRONS; FEMALE; GOLD; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IODINE RADIOISOTOPES; METAL NANOPARTICLES; MONTE CARLO METHOD; PALLADIUM; PHOTONS; RADIATION DOSAGE; RADIOISOTOPES; X-RAYS;

EID: 84889655143     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.4823787     Document Type: Article

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