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Volumn 79, Issue 2, 2003, Pages 175-185

Expression of the CCAAT/enhancer-binding proteins C/EBPα, C/EBPβ and C/EBPδ in breast cancer: Correlations with clinicopathologic parameters and cell-cycle regulatory proteins

Author keywords

Breast cancer; C EBP family; C EBP ; C EBP ; C EBP ; LAP; LIP; Western blots

Indexed keywords

CCAAT BINDING FACTOR; CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; CCAAT ENHANCER BINDING PROTEIN DELTA; CYCLIN E; ESTROGEN RECEPTOR; KI 67 ANTIGEN; LIVER ENRICHED TRANSCRIPTIONAL ACTIVATING PROTEIN 1; LIVER ENRICHED TRANSCRIPTIONAL ACTIVATING PROTEIN 2; LIVER ENRICHED TRANSCRIPTIONAL INHIBITORY PROTEIN; PROGESTERONE RECEPTOR; PROTEIN P16; UNCLASSIFIED DRUG;

EID: 0038018480     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023929504884     Document Type: Article
Times cited : (61)

References (29)
  • 1
    • 0032582677 scopus 로고    scopus 로고
    • Biological role of the CCAAT/enhancer-binding protein family of transcription factors
    • Lekstrom-Himes J, Xanthopoulos KG: Biological role of the CCAAT/enhancer-binding protein family of transcription factors. J Biol Chem 273: 28545-28548, 1998
    • (1998) J Biol Chem , vol.273 , pp. 28545-28548
    • Lekstrom-Himes, J.1    Xanthopoulos, K.G.2
  • 2
    • 0024711273 scopus 로고
    • Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein
    • Birkenmeier EH, Gwynn B, Howard S, Jerry J, Gordon JI, Landschulz WH, McKnight SL: Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein. Gene Dev 3: 1146-1156, 1989
    • (1989) Gene Dev , vol.3 , pp. 1146-1156
    • Birkenmeier, E.H.1    Gwynn, B.2    Howard, S.3    Jerry, J.4    Gordon, J.I.5    Landschulz, W.H.6    McKnight, S.L.7
  • 3
    • 0030021836 scopus 로고    scopus 로고
    • DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family
    • Osada S, Yamamoto H, Nishihara T, Imagawa M: DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family. J Biol Chem 271: 3891-3896, 1996
    • (1996) J Biol Chem , vol.271 , pp. 3891-3896
    • Osada, S.1    Yamamoto, H.2    Nishihara, T.3    Imagawa, M.4
  • 5
    • 0026050219 scopus 로고
    • Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells
    • Cao Z, Umek RM, McKnight SL: Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Gene Dev 5: 1538-1552, 1991
    • (1991) Gene Dev , vol.5 , pp. 1538-1552
    • Cao, Z.1    Umek, R.M.2    McKnight, S.L.3
  • 7
    • 0032525338 scopus 로고    scopus 로고
    • The C/EBPβ transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland
    • Robinson GW, Johnson PF. Hennighausen L, Sterneck E: The C/EBPβ transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland. Gene Dev 12: 1907-1916, 1998
    • (1998) Gene Dev , vol.12 , pp. 1907-1916
    • Robinson, G.W.1    Johnson, P.F.2    Hennighausen, L.3    Sterneck, E.4
  • 8
    • 0032588390 scopus 로고    scopus 로고
    • C/EBPα regulates generation of C/EBPβ isoforms through activation of specific proteolytic cleavage
    • Welm AL, Timchenko NA, Darlington GJ: C/EBPα regulates generation of C/EBPβ isoforms through activation of specific proteolytic cleavage. Mol Cell Biol 19: 1695-1704, 1999
    • (1999) Mol Cell Biol , vol.19 , pp. 1695-1704
    • Welm, A.L.1    Timchenko, N.A.2    Darlington, G.J.3
  • 9
    • 0035878936 scopus 로고    scopus 로고
    • Regulation of CCAAT/enhancer-binding protein-β isoform synthesis by alternative translational initiation at multiple AUG start sites
    • Xiong W, Hsieh C-C, Kurtz AJ, Rabek JP, Papaconstantinou J: Regulation of CCAAT/enhancer-binding protein-β isoform synthesis by alternative translational initiation at multiple AUG start sites. Nucleic Acids Res 29: 3087-3098, 2001
    • (2001) Nucleic Acids Res , vol.29 , pp. 3087-3098
    • Xiong, W.1    Hsieh, C.-C.2    Kurtz, A.J.3    Rabek, J.P.4    Papaconstantinou, J.5
  • 10
    • 0030888581 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein-δ (C/EBP-δ) is induced in growth-arrested mouse mammary epithelial cells
    • O'Rourke J, Yuan R, DeWille J: CCAAT/enhancer binding protein-δ (C/EBP-δ) is induced in growth-arrested mouse mammary epithelial cells. J Biol Chem 272: 6291-6296, 1997
    • (1997) J Biol Chem , vol.272 , pp. 6291-6296
    • O'Rourke, J.1    Yuan, R.2    DeWille, J.3
  • 11
    • 0029086784 scopus 로고
    • Developmentally and hormonally regulated CCAAT/enhancer-binding protein isoforms influence beta-casein gene expression
    • Raught B, Liao WS, Rosen JM: Developmentally and hormonally regulated CCAAT/enhancer-binding protein isoforms influence beta-casein gene expression. Mol Endocrinol 9: 1223-1232, 1995
    • (1995) Mol Endocrinol , vol.9 , pp. 1223-1232
    • Raught, B.1    Liao, W.S.2    Rosen, J.M.3
  • 12
    • 0032525340 scopus 로고    scopus 로고
    • C/EBPβ, but not c/EBPα, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland
    • Seagroves TN, Krnacik S, Raught B, Gay J, Burgess-Beusse B, Darlington GJ, Rosen JM: C/EBPβ, but not c/EBPα, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland. Gene Dev 12: 1917-1928, 1998
    • (1998) Gene Dev , vol.12 , pp. 1917-1928
    • Seagroves, T.N.1    Krnacik, S.2    Raught, B.3    Gay, J.4    Burgess-Beusse, B.5    Darlington, G.J.6    Rosen, J.M.7
  • 13
    • 0031283125 scopus 로고    scopus 로고
    • Overexpression of C/EBPβ-LIP, a naturally occurring, dominant-negative transcription factor, in human breast cancer
    • Zahnow CA, Younes P, Laucirica R, Rosen JM: Overexpression of C/EBPβ-LIP, a naturally occurring, dominant-negative transcription factor, in human breast cancer. J Natl Cancer I 89: 1887-1891, 1997
    • (1997) J Natl Cancer I , vol.89 , pp. 1887-1891
    • Zahnow, C.A.1    Younes, P.2    Laucirica, R.3    Rosen, J.M.4
  • 14
    • 0033889226 scopus 로고    scopus 로고
    • Expression of cell cycle regulatory proteins Rb, p16/MTS1, p27/Kip1, p21/Waf1, cyclin D1 and cyclin E in breast cancer: Correlations with expression of activating protein-1 family members
    • Milde-Langosch K, Bamberger AM, Methner C, Rieck G, Löning T: Expression of cell cycle regulatory proteins Rb, p16/MTS1, p27/Kip1, p21/Waf1, cyclin D1 and cyclin E in breast cancer: correlations with expression of activating protein-1 family members. Int J Cancer 87: 468-472, 2000
    • (2000) Int J Cancer , vol.87 , pp. 468-472
    • Milde-Langosch, K.1    Bamberger, A.M.2    Methner, C.3    Rieck, G.4    Löning, T.5
  • 15
    • 0013253204 scopus 로고    scopus 로고
    • Expression of Rb2/p130 in breast and endometrial cancer: Correlations with steroid hormone receptor status and Rb expression
    • Milde-Langosch K, Goemann C. Methner C, Rieck G, Bamberger AM, Löning T: Expression of Rb2/p130 in breast and endometrial cancer: correlations with steroid hormone receptor status and Rb expression. Brit J Cancer 85: 564-551, 2001
    • (2001) Brit J Cancer , vol.85 , pp. 564-551
    • Milde-Langosch, K.1    Goemann, C.2    Methner, C.3    Rieck, G.4    Bamberger, A.M.5    Löning, T.6
  • 16
    • 0033595634 scopus 로고    scopus 로고
    • Expression pattern of the AP-1 family in breast cancer: Association of fosB expression with a well-differentiated, receptor-positive phenotype
    • Bamberger A-M, Methner C, Lisboa BW, Städtler C, Schulte HM, Löning T, Milde-Langosch K: Expression pattern of the AP-1 family in breast cancer: association of fosB expression with a well-differentiated, receptor-positive phenotype. Int J Cancer 84: 553-558, 1999
    • (1999) Int J Cancer , vol.84 , pp. 553-558
    • Bamberger, A.-M.1    Methner, C.2    Lisboa, B.W.3    Städtler, C.4    Schulte, H.M.5    Löning, T.6    Milde-Langosch, K.7
  • 17
    • 0036139766 scopus 로고    scopus 로고
    • Functional association of PR and CCAAT/enhancer-binding protein β isoforms: Promoter-dependent cooperation between PR-B and liver-enriched inhibitory protein, or liver-enriched activatory protein and PR-A in human endometrial stromal cells
    • Christian M, Pohnke Y, Kempf R, Gellersen B, Brosens JJ: Functional association of PR and CCAAT/enhancer-binding protein β isoforms: promoter-dependent cooperation between PR-B and liver-enriched inhibitory protein, or liver-enriched activatory protein and PR-A in human endometrial stromal cells. Mol Endocrinol 16: 141-154, 2002
    • (2002) Mol Endocrinol , vol.16 , pp. 141-154
    • Christian, M.1    Pohnke, Y.2    Kempf, R.3    Gellersen, B.4    Brosens, J.J.5
  • 18
    • 0033624014 scopus 로고    scopus 로고
    • C/EBPα inhibits cell growth via direct repression of E2F-DP-mediated transcription
    • Slomiany BA, D'Arigo KL, Kelly MM, Kurtz DT: C/EBPα inhibits cell growth via direct repression of E2F-DP-mediated transcription. Mol Cell Biol 20: 5986-5997, 2000
    • (2000) Mol Cell Biol , vol.20 , pp. 5986-5997
    • Slomiany, B.A.1    D'Arigo, K.L.2    Kelly, M.M.3    Kurtz, D.T.4
  • 19
    • 0034760521 scopus 로고    scopus 로고
    • Retinoblastoma protein complexes with C/EBP proteins and activates C/EBP-mediated transcription
    • Charles A, Tang X, Crouch E, Brody JS, Xiao ZX: Retinoblastoma protein complexes with C/EBP proteins and activates C/EBP-mediated transcription. J Cell Biochem 83: 414-425, 2001
    • (2001) J Cell Biochem , vol.83 , pp. 414-425
    • Charles, A.1    Tang, X.2    Crouch, E.3    Brody, J.S.4    Xiao, Z.X.5
  • 20
    • 0034904975 scopus 로고    scopus 로고
    • Expression and function of CCAAT/enhancer binding protein beta (C/EBPβ) LAP and LIP isoforms in mouse mammary gland, tumors and cultured mammary epithelial cells
    • Dearth LR, Hutt J, Sattler A, Giglotti A, DeVille J: Expression and function of CCAAT/enhancer binding protein beta (C/EBPβ) LAP and LIP isoforms in mouse mammary gland, tumors and cultured mammary epithelial cells. J Cell Biochem 82: 357-370, 2001
    • (2001) J Cell Biochem , vol.82 , pp. 357-370
    • Dearth, L.R.1    Hutt, J.2    Sattler, A.3    Giglotti, A.4    DeVille, J.5
  • 21
    • 0034335414 scopus 로고    scopus 로고
    • C/EBPβ (CCAAT/enhancer binding protein) controls cell fate determination during mammary gland development
    • Seagroves TN, Lydon JP, Hovey RC, Vonderhaar BK, Rosen JM: C/EBPβ (CCAAT/enhancer binding protein) controls cell fate determination during mammary gland development. Mol Endocrinol 14: 359-368, 2000
    • (2000) Mol Endocrinol , vol.14 , pp. 359-368
    • Seagroves, T.N.1    Lydon, J.P.2    Hovey, R.C.3    Vonderhaar, B.K.4    Rosen, J.M.5
  • 23
  • 24
    • 0034895071 scopus 로고    scopus 로고
    • Overexpression of the p16 cell cycle inhibitor in breast cancer is associated with a more malignant phenotype
    • Milde-Langosch K, Bamberger A-M, Rieck G, Kelp B, Löning T: Overexpression of the p16 cell cycle inhibitor in breast cancer is associated with a more malignant phenotype. Breast Cancer Res Tr 67: 61-70, 2001
    • (2001) Breast Cancer Res Tr , vol.67 , pp. 61-70
    • Milde-Langosch, K.1    Bamberger, A.-M.2    Rieck, G.3    Kelp, B.4    Löning, T.5
  • 25
    • 0035805495 scopus 로고    scopus 로고
    • Regulated nuclear-cytoplasmic localization of CCAAT/enhancer-binding protein delta in osteoblasts
    • Billiard J, Umayahara Y, Wiren K, Centrella M, McCarthy TL, Rotwein P: Regulated nuclear-cytoplasmic localization of CCAAT/enhancer-binding protein delta in osteoblasts. J Biol Chem 276: 15354-15361, 2001
    • (2001) J Biol Chem , vol.276 , pp. 15354-15361
    • Billiard, J.1    Umayahara, Y.2    Wiren, K.3    Centrella, M.4    McCarthy, T.L.5    Rotwein, P.6
  • 26
    • 0035138818 scopus 로고    scopus 로고
    • A role for CCAAT/enhancer-binding protein-β-liver-enriched inhibitory protein in mammary epithelial cell proliferation
    • Zahnow CA, Cardiff RD, Laucirica R, Medina D, Rosen JM: A role for CCAAT/enhancer-binding protein-β-liver-enriched inhibitory protein in mammary epithelial cell proliferation. Cancer Res 61: 261-269, 2001
    • (2001) Cancer Res , vol.61 , pp. 261-269
    • Zahnow, C.A.1    Cardiff, R.D.2    Laucirica, R.3    Medina, D.4    Rosen, J.M.5
  • 27
    • 0032548965 scopus 로고    scopus 로고
    • Retinoblastoma and p16 proteins in mammary carcinoma: Their relationship to cyclin D1 and histological parameters
    • Dublin EA, Patel NK, Gillett CE, Smith P, Peters G, Barnes DM: Retinoblastoma and p16 proteins in mammary carcinoma: their relationship to cyclin D1 and histological parameters. Int J Cancer 79: 71-75, 1998
    • (1998) Int J Cancer , vol.79 , pp. 71-75
    • Dublin, E.A.1    Patel, N.K.2    Gillett, C.E.3    Smith, P.4    Peters, G.5    Barnes, D.M.6
  • 29
    • 0034181477 scopus 로고    scopus 로고
    • Increased expression of the transcription factor CCAAT/enhancer binding protein-beta (c/EBPβ) and C/EBPζ (CHOP) correlate with invasiveness of human colorectal cancer
    • Rask K, Thorn M, Ponten F, Kraaz W, Sundfeldt K, Hedin L, Enerback S: Increased expression of the transcription factor CCAAT/enhancer binding protein-beta (c/EBPβ) and C/EBPζ (CHOP) correlate with invasiveness of human colorectal cancer. Int J Cancer 86: 337-343, 2000
    • (2000) Int J Cancer , vol.86 , pp. 337-343
    • Rask, K.1    Thorn, M.2    Ponten, F.3    Kraaz, W.4    Sundfeldt, K.5    Hedin, L.6    Enerback, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.