DATS suppresses growth of esophageal squamous cell carcinoma by regulation of ERK1/2

Clinical Laboratory

Volumn 61, Issue 3-4, 2015, Pages 315-322

  Wang, Feng ^a   Li, Shenglei ^a   Wang, Liuxing ^a   Zong, Hong ^a   Fan, Qingxia ^a  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

Author keywords

DATS; ERK1 2; ESCC; Migration; Proliferation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CRYSTAL VIOLET; DIALLYL TRISULFIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; AKT1 PROTEIN, HUMAN; ALLYL COMPOUND; ANTINEOPLASTIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE; SULFIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FILTERS AND MEMBRANES; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING; ANIMAL; CANCER TRANSPLANTATION; CELL MOTION; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; ESOPHAGUS TUMOR; GENE EXPRESSION REGULATION; METABOLISM; NUDE MOUSE; PHOSPHORYLATION; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE;

MUS MUSCULUS;

ALLYL COMPOUNDS; ANIMALS; ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ESOPHAGEAL NEOPLASMS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SULFIDES;

EID: 84929400940     PISSN: 14336510     EISSN: None     Source Type: Journal    
DOI: 10.7754/Clin.Lab.2014.140806     Document Type: Article

References (26)

1. Parkin DM, Bray FI, Devesa SS. Cancer burden in the year 2000 the global picture. Eur J Cancer 2001;37:S4S66.
2. Xing D, Tan W, Lin D. Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population. Oncol Rep 2003;10:1615-23.
3. Umar SB, Fleischer DE. Esophageal cancer: epidemiology, pathogenesis and prevention. Gastroen Hepatology 2008;5:517-26.
4. Blot WJ, McLaughlin JK. The changing epidemiology of esophageal cancer. Semin Oncol 1999;26(Suppl 15):2-8.
5. Stoner GD, Wang LS, Chen T. Chemoprevention of esophageal squamous cell carcinoma. Toxicol Appl Pharmacol 2007;224:337-49.
6. Seki T, Hosono T, Hosono-Fukao T, et al. Anticancer effects of diallyl trisulfide derived from garlic. Asia Pac J Clin Nutr 2008;17:249-52.
7. Rivilin RS. Historical perspective on the use of garlic. J Nutr 2001;131:951S-4S.
8. Hosono T, Fukao T, Ogihara J, et al. Diallyl trisulfide suppresses the proliferation and induces apoptosis of human colon cancer cells through oxidative modification of h-tubulin. J Biol Chem 2005;280:41487-93.
9. Nakagawa H, Tsuta K, Kiuchi K, et al. Growth inhibitory effects of diallyl disulfide on human breast cancer cell lines. Carcinogenesis 2001;22:891-7.
10. Xiao D, Herman-Antosiewicz A, Antosiewicz J, et al. Diallyl trisulfide-induced G2-M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and hyperphosphorylation of Cdc25C. Oncogene 2005;24:6256-68.
11. Wang HC, Yang JH, Hsieh SC et al. Allyl sulfides inhibit cell growth of skin cancer cells through induction of DNA damage mediated G2/M arrest and apoptosis. J Agric Food Chem 2010;58:7096-103.
12. Wargovich MJ, Imada O, Stephens LC. Initiation and post-initiation chemopreventive effects of diallyl sulfide in esophageal carcinogenesis. Cancer Lett 1992;64:39-42.
13. De Luca A, Maiello MR, D'Alessio A, et al. The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches. Expert Opin Ther Targets 2012;16:S17-27.
14. Junttila MR, Li SP, Westermarck J. Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J 2008;22:954-65.
15. Ballif BA, Blenis J. Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK) - MAPK cell survival signals. Cell Growth Differ 2001;12:397-408.
16. McCubrey JA, Steelman LS, Chappell WH, et al. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta 2007;1773:1263-84.
17. Zhuang S, Schnellmann RG. A death-promoting role for extracellular signal-regulated kinase. J Pharmacol Exp Ther 2006;319:991-7.
18. Shi D, Guo W, Chen W, et al. Nicotine promotes proliferation of human nasopharyngeal carcinoma cells by regulating α7AChR, ERK, HIF-lα and VEGF/PEDF signaling. PLoS One 2012;7(8):e43898.
19. Park YS, Cho NJ. EGFR and PKC are involved in the activation of ERK1/2 and p90 RSK and the subsequent proliferation of SNU-407 colon cancer cells by muscarinic acetylcholine receptors. Mol Cell Biochem 2012;370:191-8.
20. Wallace EM, Lyssikatos JP, Yeh T, et al. Progress towards therapeutic small molecule MEK inhibitors for use in cancer therapy. Curr Top Med Chem 2005;5:215-29.
21. Knowles LM, Milner JA. Diallyl disulfide induces ERK phosphorylation and alters gene expression profiles in human colon tumor cells. J Nutr 2003;133:2901-6.
22. Hui C, Jun. W, Ya LN, et al. Effect of Allium sativum (garlic) diallyl disulfide (DADS) on human non-small cell lung carcinoma H1299 cells. Trap Biomed 2008;25:37-45.
23. Shin DY, Kim GY, Lee JH, et al. Apoptosis Induction of Human Prostate Carcinoma DU145 Cells by Diallyl Disulfide via Modulation of JNK and PI3K/AKT Signaling Pathways. Int J Mol Sci 2012;13:14158-71.
24. Xiao D, Singh SV. Diallyl trisulfide, a constituent of processed garlic, inactivates Akt to trigger mitochondrial translocation of BAD and caspase-mediated apoptosis in human prostate cancer cells. Carcinogenesis 2006;27:533-40.
25. Yang JS, Kok LF, Lin YH, et al. Diallyl disulfide inhibits WEHI-3 leukemia cells in vivo. Anticancer Res 2006;26:219-25.
26. Zhao J, Huang WG, He, J et al. Diallyl disulfide suppresses growth of HL-60 cell through increasing histone acetylation and p21WAFl expression in vivo and in vitro. Acta Pharmacol Sin 2006;27:1459-66.