Escherichia coli maltose-binding protein induces M1 polarity of RAW264.7 macrophage cells via a TLR2- and TLR4-dependent manner

International Journal of Molecular Sciences

Volumn 16, Issue 5, 2015, Pages 9896-9909

  Wang, Wan ^a   Yuan, Hong Yan ^a   Liu, Guo Mu ^a   Ni, Wei Hua ^a   Wang, Fang ^a   Tai, Gui Xiang ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

Classically activated macrophages; Maltose binding protein; Toll like receptor 2; Toll like receptor 4

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; MALTOSE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; AUTACOID; BIOLOGICAL MARKER; CYTOKINE; ESCHERICHIA COLI PROTEIN; HLA ANTIGEN CLASS 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MALE PROTEIN, E COLI; NITRIC OXIDE; PERIPLASMIC BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL POLARITY; CELL VIABILITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNE RESPONSE; MACROPHAGE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PINOCYTOSIS; POLARIZATION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL SURVIVAL; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; MACROPHAGE; METABOLISM; RAW 264.7 CELL LINE; SECRETION (PROCESS); UPREGULATION;

ESCHERICHIA COLI; MURINAE;

ANIMALS; BIOMARKERS; CELL POLARITY; CELL SURVIVAL; CYTOKINES; ESCHERICHIA COLI PROTEINS; HISTOCOMPATIBILITY ANTIGENS CLASS I; INFLAMMATION MEDIATORS; MACROPHAGES; MAP KINASE SIGNALING SYSTEM; MICE; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PERIPLASMIC BINDING PROTEINS; PINOCYTOSIS; RAW 264.7 CELLS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; UP-REGULATION;

EID: 84929376643     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms16059896     Document Type: Article

References (22)

1. Boos, W.; Shuman, H. Maltose/maltodextrin system of Escherichia coli: Transport, metabolism, and regulation. Microbiol. Mol. Biol. Rev. 1998, 62, 204–229.
2. Riggs, P. Expression and purification of recombinant proteins by fusion to maltose-binding protein. Mol. Biotechnol. 2000, 15, 51–63.
3. Fox, J.D.; Kapust, R.B.; Waugh, D.S. Single amino acid substitutions on the surface of Escherichia coli maltose-binding protein can have a profound impact on the solubility of fusion proteins. Protein Sci. 2001, 10, 622–630.
4. Witteveldt, J.; Vlak, J.M.; van Hulten, M.C. Protection of Panaeus monodon against white spot syndrome virus using a WSSV subunit vaccine. Fish Shellfish Immunol. 2004, 16, 571–579.
5. Kang, Q.Z.; Duan, G.C.; Fan, Q.T.; Xi, Y.L. Fusion expression of Helicobacter pylori neutrophil-activating protein in E. coli. World J. Gastroenterol. 2005, 11, 454–456.
6. Du, Y.; Hashizume, T.; Kurita-Ochiai, T.; Yuzawa, S.; Abiko, Y.; Yamamoto, M. Nasal Immunization with a fusion protein consisting of the hemagglutinin A antigenic region and the maltose-binding protein elicits CD11c+ CD8+ dendritic cells for induced long-term protective immunity. Infect. Immun. 2011, 79, 895–904.
7. Fernandez, S.; Palmer, D.R.; Simmons, M.; Sun, P.; Bisbing, J.; McClain, S.; Mani, S.; Burgess, T.; Gunther, V.; Sun, W. Potential role for Toll-like receptor 4 in mediating Escherichia coli maltose-binding protein activation of dendritic cells. Infect. Immun. 2007, 75, 1359–1363.
8. Zhang, Q.Y.; Ni, W.H.; Zhao, X.X.; Wang, F.L.; Gao, Z.; Tai, G.X. Synergistic antitumor effects of Escherichia coli maltose binding protein and Bacillus Calmette-Guerin in a mouse lung carcinoma model. Immunol. Lett. 2011, 136, 108–113.
9. Ni, W.H.; Zhang, Q.Y.; Liu, G.M.; Wang, F.L.; Yuan, H.Y.; Zhang, X.; Xie, F.; Li, Q.S.; Tai, G.X. Escherichia coli maltose-binding protein activates mouse peritoneal macrophages and induces M1 polarization via TLR2/4 in vivo and in vitro. Int. Immunopharmacol. 2014, 21, 171–180.
10. Zhao, X.X.; Ni, W.H.; Zhang, Q.Y.; Wang, F.L.; Li, Y.Y.; Sun, X.X.; Liu, Z.H.; Tai, G.X. Maltose-binding protein isolated from Escherichia coli induces Toll-like receptor 2-mediated viability in U937 cells. Clin. Transl. Oncol. 2011, 13, 509–518.
11. Kim, J.H.; Kim, D.H.; Baek, S.H.; Lee, H.J.; Kim, M.R.; Kwon, H.J.; Lee, C.H. Rengyolone inhibits inducible nitric oxide synthase expression and nitric oxide production by down-regulation of NF-κB and p38 MAP kinase activity in LPS-stimulated RAW264.7 cells. Biochem. Pharmacol. 2006, 71, 1198–1205.
12. Chiou, W.F.; Don, M.J.; Liao, J.F.; Wei, B.L. Psoralidin inhibits LPS-induced iNOS expression via repressing Syk-mediated activation of PI3K-IKK-IκB signaling pathways. Eur. J. Pharmacol. 2011, 650, 102–109.
13. Wang, S.Y.; Tai, G.X.; Zhang, P.Y.; Mu, D.P.; Zhang, X.J.; Liu, Z.H. Inhibitory effect of activin A on activation of lipopolysaccharide-stimulated mouse macrophage RAW264.7 cells. Cytokine 2008, 42, 85–91.
14. Ge, J.Y.; Wang, Y.N.; Feng, Y.; Liu, H.Y.; Cui, X.L.; Chen, F.F.; Tai, G.X.; Liu, Z.H. Direct effects of activin A on the activation of mouse macrophage RAW264.7 cells. Cell. Mol. Immunol. 2009, 6, 129–133.
15. Stout, R.D.; Jiang, C.; Matta, B.; Tietzel, I.; Watkins, S.K.; Suttles, J. Macrophages sequentially change their functional phenotype in response to changes in microenvironment influences. J. Immunol. 2005, 175, 342–349.
16. Akira, S.; Hoshino, K. Myeloid differentiation factor 88-dependent and -independent pathways in Toll-like receptor signaling. J. Infect. Dis. 2003, 187, S356–S363.
17. Bjorkbacka, H.; Fitzgerald, K.A.; Huet, F.; Li, X.; Gregory, J.A.; Lee, M.A.; Ordija, C.M.; Dowley, N.E.; Golenbock, D.T.; Freeman, M.W. The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades. Physiol. Genomics 2004, 19, 319–330.
18. Laird, M.; Rhee, S.H.; Perkins, D.J.; Medvedev, A.E.; Piao, W.; Fenton, M.J.; Vogel, S.N. TLR4/MyD88/PI3K interactions regulate TLR4 signaling. J. Leukoc. Biol. 2009, 85, 966–977.
19. Duff, G.W.; Atkins, E. The inhibitory effect of polymyxin B on endotoxin-induced endogenous pyrogen production. J. Immunol. Methods 1982, 52, 333–340.
20. Lien, E.; Means, T.K.; Heine, H.; Yoshimura, A.; Kusumoto, S.; Fukase, K.; Fenton, M.J.; Oikawa, M.; Qureshi, N.; Monks, B. et al. Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. J. Clin. Investig. 2000, 105, 497–504.
21. Glushkova, O.V.; Parfenyuk, S.B.; Khrenov, M.O.; Novoselova, T.V.; Lunin, S.M.; Fesenko, E.E.; Novoselova, E. G. Inhibitors of TLR-4, NF-κB, and SAPK/JNK signaling reduce the toxic effect of lipopolysaccharide on RAW 264.7 cells. J. Immunotoxicol. 2013, 10, 133–140.
22. Yu, H.; Ha, T.; Liu, L.; Wang, X.; Gao, M.; Kelley, J.; Kao, R.; Williams, D.; Li, C. Scavenger receptor A (SR-A) is required for LPS-induced TLR4 mediated NF-κB activation in macrophages. Biochim. Biophys. Acta 2012, 1823, 1192–1198.