Pandemic swine-origin H1N1 influenza virus replicates to higher levels and induces more fever and acute inflammatory cytokines in cynomolgus versus rhesus monkeys and can replicate in common marmosets

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Mooij, Petra ^a   Koopman, Gerrit ^a   Mortier, Daniëlla ^a   Van Heteren, Melanie ^a   Oostermeijer, Herman ^a   Fagrouch, Zahra ^a   De Laat, Rudy ^a   Kobinger, Gary ^b   Li, Yan ^b   Remarque, Edmond J ^a   Kondova, Ivanela ^a   Verschoor, Ernst J ^a   Bogers, Willy M J M ^a  

^a BIOMEDICAL PRIMATE RESEARCH CENTRE   (Netherlands)

^b PUBLIC HEALTH AGENCY OF CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE DERIVATIVE; CYTOKINE; VIRUS RECEPTOR; AUTACOID; CHEMOKINE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; BRONCHUS; CALLITRICHINAE; CONTROLLED STUDY; FEVER; INFECTION SENSITIVITY; INFLUENZA A (H1N1); INFLUENZA VIRUS A H1N1; MACACA FASCICULARIS; MALE; NEUTROPHIL; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RESPIRATORY DISTRESS; RHESUS MONKEY; SPECIES DIFFERENCE; T LYMPHOCYTE ACTIVATION; TRACHEA; UPPER RESPIRATORY TRACT INFECTION; VIRUS REPLICATION; ANIMAL; BLOOD; CALLITHRIX; DISEASE MODEL; HOST PATHOGEN INTERACTION; HOST RANGE; HUMAN; IMMUNOLOGY; INFLUENZA A VIRUS (H1N1); INFLUENZA, HUMAN; LUNG; METABOLISM; ORTHOMYXOVIRUS INFECTION; PANDEMIC; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; PIG; VIROLOGY; VIRULENCE; VIRUS LOAD;

CALLITHRIX JACCHUS; HUMAN INFLUENZA VIRUS; INFLUENZA A VIRUS; MACACA; MACACA MULATTA; ORTHOMYXOVIRIDAE; PRIMATES; SUIDAE;

ANIMALS; CALLITHRIX; CHEMOKINES; CYTOKINES; DISEASE MODELS, ANIMAL; FEVER; HOST SPECIFICITY; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLAMMATION MEDIATORS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; LUNG; MACACA FASCICULARIS; MACACA MULATTA; MALE; ORTHOMYXOVIRIDAE INFECTIONS; PANDEMICS; RECEPTORS, VIRUS; SWINE; VIRAL LOAD; VIRULENCE; VIRUS REPLICATION;

EID: 84929340869     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0126132     Document Type: Article

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