FUS regulates AMPA receptor function and FTLD/ALS-associated behaviour via GluA1 mRNA stabilization

Nature Communications

Volumn 6, Issue , 2015, Pages

  Udagawa, Tsuyoshi ^a,b   Fujioka, Yusuke ^a   Tanaka, Motoki ^a   Honda, Daiyu ^a   Yokoi, Satoshi ^a   Riku, Yuichi ^a   Ibi, Daisuke ^a,d   Nagai, Taku ^a   Yamada, Kiyofumi ^a   Watanabe, Hirohisa ^a   Katsuno, Masahisa ^a   Inada, Toshifumi ^b   Ohno, Kinji ^a   Sokabe, Masahiro ^a   Okado, Haruo ^c   Ishigaki, Shinsuke ^a   Sobue, Gen ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMANITIN; AMPA RECEPTOR; DACTINOMYCIN; FUSED IN SARCOMA PROTEIN; GLUA1 RECEPTOR; MESSENGER RNA; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; FUS PROTEIN, MOUSE; PROTEIN SUBUNIT; RNA BINDING PROTEIN FUS;

AMPLITUDE; ANIMAL; CHEMICAL BINDING; GENE EXPRESSION; RNA;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN MATURATION; CONTROLLED STUDY; DENDRITIC SPINE; EXCITATORY POSTSYNAPTIC POTENTIAL; FRONTOTEMPORAL DEMENTIA; GENE SILENCING; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; HYPERACTIVITY; IN VIVO STUDY; MORPHOGENESIS; MOUSE; NERVE CELL CULTURE; NONHUMAN; POLYADENYLATION; PROTEIN FUNCTION; PROTEIN RNA BINDING; RECEPTOR DOWN REGULATION; RNA STABILITY; SOCIAL INTERACTION; SYNAPSE; SYNAPTIC TRANSMISSION; ANIMAL; BRAIN CORTEX; C57BL MOUSE; CELL CULTURE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NERVE CELL; PHYSIOLOGY; PROTEIN SUBUNIT;

ANIMALIA;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BEHAVIOR, ANIMAL; CELLS, CULTURED; CEREBRAL CORTEX; FRONTOTEMPORAL LOBAR DEGENERATION; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HIPPOCAMPUS; MICE; MICE, INBRED C57BL; NEURONS; PROTEIN SUBUNITS; RECEPTORS, AMPA; RNA, MESSENGER; RNA-BINDING PROTEIN FUS;

EID: 84929340365     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8098     Document Type: Article

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