Histone deacetylase 6 (HDAC6) promotes the pro-survival activity of 14-3-3ζ via deacetylation of lysines within the 14-3-3ζ binding pocket

Journal of Biological Chemistry

Volumn 290, Issue 20, 2015, Pages 12487-12496

  Mortenson, Jeffrey B ^a   Heppler, Lisa N ^a   Banks, Courtney J ^a   Weerasekara, Vajira K ^a   Whited, Matthew D ^a   Piccolo, Stephen R ^b   Johnson, William E ^c   Thompson, J Will ^d   Andersen, Joshua L ^a  

^a Brigham Young University   (United States)

^b BRIGHAM YOUNG UNIVERSITY   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; PROTEINS;

BINDING ACTIVITIES; BINDING POCKETS; BINDING PROTEINS; DEPHOSPHORYLATIONS; HISTONE DEACETYLASES; ONCOGENIC PATHWAYS; POSITIVE CHARGES; PROTEIN-PROTEIN INTERFACE;

AMINO ACIDS;

BINDING PROTEIN; HISTONE DEACETYLASE 6; LYSINE; MUTANT PROTEIN; PHOSPHOPROTEIN; PROTEIN 14 3 3 ZETA PROTEIN; PROTEIN BAD; SERINE; THREONINE; UNCLASSIFIED DRUG; BAD PROTEIN, HUMAN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HDAC6 PROTEIN, HUMAN; HISTONE DEACETYLASE; PROTEIN 14 3 3; TBC1D4 PROTEIN, HUMAN; YWHAE PROTEIN, HUMAN;

ACETYLATION; ARTICLE; BINDING SITE; CONTROLLED STUDY; CYTOTOXICITY; DEACETYLATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SCREENING; SURFACE CHARGE; AMINO ACID SUBSTITUTION; CELL SURVIVAL; GENETICS; HEK293 CELL LINE; METABOLISM; MISSENSE MUTATION;

14-3-3 PROTEINS; ACETYLATION; AMINO ACID SUBSTITUTION; BCL-ASSOCIATED DEATH PROTEIN; BINDING SITES; CELL SURVIVAL; GTPASE-ACTIVATING PROTEINS; HEK293 CELLS; HISTONE DEACETYLASES; HUMANS; LYSINE; MUTATION, MISSENSE;

EID: 84929337566     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.607580     Document Type: Article

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