Estrogen plus progestin increase superoxide dismutase and total antioxidant capacity in postmenopausal women

Climacteric

Volumn 18, Issue 3, 2015, Pages 379-388

  Unfer, T C ^a   Figueiredo, C G ^a   Zanchi, M M ^a   Maurer, L H ^a   Kemerich, D M ^a   Duarte, M M F ^b   Konopka, C K ^a   Emanuelli, T ^a  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^b UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

Author keywords

Antioxidant capacity; Estrogen; Hormone therapy; Menopause; Progestin; Superoxide dismutase

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ASPARTATE AMINOTRANSFERASE; CARBONYL DERIVATIVE; CATALASE; CHOLESTEROL; CREATININE; ESTROGEN; GESTAGEN; GLUTATHIONE PEROXIDASE; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLASMA PROTEIN; PROGESTERONE; PROTEIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRIACYLGLYCEROL; URIC ACID; ANTIOXIDANT; ESTRADIOL;

ADULT; AGE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ANTIOXIDANT ASSAY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD ANALYSIS; BODY MASS; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CREATININE BLOOD LEVEL; CROSS-SECTIONAL STUDY; ENZYME ACTIVITY; FEMALE; HEMATOCRIT; HEMATOLOGICAL PARAMETERS; HEMOGLOBIN BLOOD LEVEL; HORMONAL THERAPY; HORMONE SUBSTITUTION; HUMAN; LIPID OXIDATION; OXIDATION; OXIDATIVE STRESS; POSTMENOPAUSE; PREMENOPAUSE; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; TRIACYLGLYCEROL BLOOD LEVEL; URIC ACID BLOOD LEVEL; AGED; BLOOD; ESTROGEN THERAPY; METABOLISM; MIDDLE AGED; OXIDATION REDUCTION REACTION; PROCEDURES;

ADULT; AGED; ANTIOXIDANTS; CATALASE; CROSS-SECTIONAL STUDIES; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; ESTROGENS; FEMALE; GLUTATHIONE PEROXIDASE; HUMANS; MIDDLE AGED; OXIDATION-REDUCTION; POSTMENOPAUSE; PREMENOPAUSE; PROGESTINS; SUPEROXIDE DISMUTASE;

EID: 84929319685     PISSN: 13697137     EISSN: 14730804     Source Type: Journal    
DOI: 10.3109/13697137.2014.964669     Document Type: Article

References (51)

1. Hale GE, Zhao X, Hughes CL, et al. Endocrine features of menstrual cycles in middle and late reproductive age and the menopausal transition classified according to the Staging of Reproductive Aging Workshop (STRAW) staging system. J Clin Endocrinol Metab 2007;92:3060-7
2. Aquino EM, Barreto SM, Bensenor IM, et al. Brazilian Longitudinal Study of Adult Health (ELSA-Brasil): Objectives and design. Am J Epidemiol 2012;175:315-24
3. Baquer NZ, Taha A, Kumar P, et al. A metabolic and functional overview of brain aging linked to neurological disorders. Biogerontology 2009;10:377-413
4. Trevisan M, Browne R, Ram M, et al. Correlates of markers of oxidative status in the general population. Am J Epidemiol 2001;154:348-56
5. Signorelli SS, Neri S, Sciacchitano S, et al. Behavior of some indicators of oxidative stress in postmenopausal and fertile women. Maturitas 2006;53:77-82
6. Sánchez-Rodríguez MA, Zacarías-Flores M, Arronte-Rosales A, et al. Menopause as risk factor for oxidative stress. Menopause 2012;19:361-7
7. Miquel J, Ramírez-BoscáA, Ramírez-Bosca JV, Alperi JD. Menopause: a review on the role of oxygen stress and favorable effects of dietary antioxidants. Arch Gerontol Geriatr 2006;42:289-306
8. WHI Writing Group For The Women's Health Initiative Investigators. Risk and benefits of estrogen plus progesterone in healthy postmenopausal women. JAMA 2002;288:321-33
9. Rossouw JE, Prentice RL, Manson JE, et al. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA 2007;297:1465-77
10. Hulley S, Grady D, Bush T, et al. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. JAMA 1998;280:605-13
11. Skouby SO, Jespersen J. Progestins in HRT: sufferance or desire? Maturitas 2009;62:371-5
12. Özden S, Dildar K, Kadir YH, Gülizar K. The effects of hormone replacement therapy on lipid peroxidation and antioxidant status. Maturitas 2001;38:165-70
13. Bednarek-Tupikowsa G, Bohdanowicz-Pawlak A, Bidzinska B, et al. Serum lipid peroxides and total antioxidant status in postmenopausal women on hormone replacement therapy. Gynecol Endocrinol 2004;19:57-63
14. Gómez CE, Mora SQ. HRT decreases DNA and lipid oxidation in postmenopausal women. Climacteric 2013;16:104-10
15. Bednarek-Tupikowska G, Tworowska U, Jedrychowska I, et al. Effects of oestradiol and oestroprogestin on erythrocyte antioxidative enzyme system activity in postmenopausal women. Clin Endocrinol (Oxf) 2006;64:463-8
16. Unfer TC, Conterato GM, Da Silva JC, et al. Influence of hormone replacement therapy on blood antioxidant enzymes in menopausal women. Clin Chim Acta 2006;369:73-7
17. Gökku u C, Özbek Z, Tata G. Hormone replacement therapy: relation to homocysteine and prooxidant-antioxidant status in healthy postmenopausal women. Arch Gynecol Obstet 2012;285:733-9
18. Haliwell B, Grootveld M. The measurement of free radical reactions in humans. Some thoughts for future experimentation. FEBS Lett 1987;213:9-16
19. Subbiah MT. Mechanisms of cardioprotection by estrogens. Proc Soc Exp Biol Med 1998;217:23-9
20. Huber LA, Scheffler E, Poll T, et al. 17 β-estradiol inhibits LDL oxidation and cholesteryl macrophages. Free Radic Res 1989;8:167-73
21. Subbiah MT, Kessel B, Agrawal M, et al. Antioxidant potential of specific estrogens on lipid peroxidation. J Clin Endocrinol Metab 1993;77:1095-7
22. Ayres S, Abplanalp W, Liu J, Subbiah MT. Mechanism involved in the protective effect of estradiol-17 β on lipid peroxidation and DNA damage. Am J Physiol 1998;274:1002-8
23. Thibodeau PA, Kachadourian R, Lemay R, et al. In vitro pro- and antioxidant properties of estrogens. J Steroid Biochem Mol Biol 2002;81:227-36
24. Wójcik M, Kosior-Korzecka U, Bobowiec R. Cytoprotective action of 17 β-oestradiol against iron-induced hepatic oxidative stress in vitro. Bull Vet Inst Pulawy 2010;54:259-63
25. Al-Gubory KH, Bolifraud P, Garrel C. Regulation of key antioxidant enzymatic systems in the sheep endometrium by ovarian steroids. Endocrinology 2008;149:4428-34
26. Tranquilli AL, Mazzanti L, Cugini AM, et al. Transdermal estradiol and medroxyprogesterone acetate in hormone replacement therapy are both antioxidants. Gynecol Endocrinol 1995;9:137-41
27. Gökkusu C, Tata G, Ademo g lu E, Tamer S. The benefits of hormone replacement therapy on plasma and platelet antioxidant status and fatty acid composition in healthy postmenopausal women. Platelets 2010;21:439-44
28. Strehlow K, Rotter S, Wassmann S, et al. Modulation of antioxidant enzyme expression and function by estrogen. Circ Res 2003;93:170-7
29. Moorthy K, Sharma D, Basir SF, Baquer NZ. Administration of estradiol and progesterone modulate the activities of antioxidant enzyme and aminotransferases in naturally menopausal rats. Exp Gerontol 2005;40:295-302
30. Unfer TC, Maurer LH, Kemerich DM, et al. Non-genomic, direct modulatory effect of 17b-estradiol, progesterone and their synthetic derivatives on the activity of human erythrocyte CuZn superoxide dismutase. Free Radic Res 2013;47:219-32
31. Sugino N, Karube-Harada A, Kashida S, et al. Differential regulation of copper-zinc superoxide dismutase and manganese superoxide dismutase by progesterone withdrawal in human endometrial stromal cells. Mol Hum Reprod 2002;8:68-74
32. Wassmann K, Wassmann S, Nickenig G. Progesterone antagonizes the vasoprotective effect of estrogen on antioxidant enzyme expression and function. Circ Res 2005;97:1046-54
33. Soules MR, Sherman S, Parrott, E et al. Stages of Reproductive Aging Workshop (STRAW). J Women Health Gen-B 2001;10:843-8
34. Spitz DR, Oberley L W. An assay for superoxide dismutase activity in mammalian tissue homogenates. Anal Biochem 1989;179:8-18
35. Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967;70:158-69
36. Aebi H. Catalase in vitro. Methods Enzymol 1984;105:121-6
37. Ohkawa H, Ohishi N, Yagi K. Assay for lipid hidroperoxides in animal tissue by thiobarbituric acid reaction. Anal Biochem 1979;95:351-8
38. Levine RL, Garland D, Oliver CN, et al. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 1990;186:464-78
39. Benzie IFF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay. Anal Biochem 1996;239:70-6
40. Ceballos-Picot, Trivier J M, Nicole A, et al. Age-correlated modifications of copper-zinc superoxide dismutase and glutathionerelated enzyme activities in human erythrocytes. Clin Chem 1992;38:66-70
41. Kim HT, Kim HY, Nam JW, et al. Study of 5'-flanking region of human Cu/Zn superoxide dismutase. Biochem Biophys Res Commun 1994;201:1526-33
42. Wan XS, Devalaraja MN, St Clair DK. Molecular structure and organization of the human manganese superoxide dismutase gene. DNA Cell Biol 1994;13:1127-36
43. Holley AK, Kiningham KK, Spitz DR, et al. Progestin stimulation of manganese superoxide dismutase and invasive properties in T47D human breast cancer cells. J Steroid Biochem Mol Biol 2009;117:23-30
44. Azevedo RB, Lacava ZGM, Miyasaka CK, et al. Regulation of antioxidant enzyme activities in male and female rat macrophages by sex steroids. Braz J Med Biol Res 2001;34:683-7
45. Lutoslawska G, Tkaczyk J, Panczenko-Kresowska B, et al. Plasma TBARS, blood GSH concentrations, and erythrocyte antioxidant enzyme activities in regularly menstruating women with ovulatory and anovulatory menstrual cycles. Clin Chim Acta 2003;331:159-63
46. Borrás C, Gambini J, Gómez-Cabrera C, et al. 17 β-oestradiol up-regulates longevity-related, antioxidant enzyme expression via the ERK1 and ERK2 [MAPK]/NF κ B cascade. Aging Cell 2005;4:113-18
47. Pinho RA, Andrades ME, Oliveira MR, et al. Imbalance in SOD/CAT activities in rat skeletal muscles submitted to treadmill training exercise. Cell Biol Int 2006;30:848-53
48. Delibasi T, Kockar C, Celik A, Kockar O. Antioxidant effects of hormone replacement therapy in postmenopausal women. Swiss Med Wkly 2006;136:510-14
49. Polac I, Borowiecka M, Wilamowska A, Nowak P. Oxidative stress measured by carbonyl groups level in postmenopausal women after oral and transdermal hormone therapy. J Obstet Gynaecol 2012;38:1177-81
50. Kumar P, Kale RK, McLean P, Baquer NZ. Protective effects of 17 β estradiol on altered age related neuronal parameters in female rat brain. Neurosci Lett 2011;502:56-60
51. Kumar P, Taha A, Kale RK, et al. Physiological and biochemical effects of 17 β estradiol in aging female rat brain. Exp Gerontol 2011;46:597-605