메뉴 건너뛰기




Volumn 17, Issue 1, 2015, Pages

Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: A meta-analysis of genome-wide association study in a Japanese population

(32)  Terao, Chikashi a   Ohmura, Koichiro a   Kochi, Yuta b   Ikari, Katsunori c   Okada, Yukinori d   Shimizu, Masakazu a   Nishina, Naoshi e   Suzuki, Akari b   Myouzen, Keiko b   Kawaguchi, Takahisa a   Takahashi, Meiko a   Takasugi, Kiyoshi f   Murasawa, Akira g   Mizuki, Shinichi h   Iwahashi, Mitsuhiro i   Funahashi, Keiko j   Natsumeda, Masamitsu k   Furu, Moritoshi a   Hashimoto, Motomu a   Ito, Hiromu a   more..

b RIKEN   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC CITRULLINATED PEPTIDE ANTIBODY; HLA ANTIGEN; CYCLIC CITRULLINATED PEPTIDE; CYCLOPEPTIDE;

EID: 84929298327     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/s13075-015-0623-4     Document Type: Article
Times cited : (24)

References (43)
  • 1
    • 0034121235 scopus 로고    scopus 로고
    • Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins
    • MacGregor AJ, Snieder H, Rigby AS, Koskenvuo M, Kaprio J, Aho K, et al. Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis Rheum. 2000;43:30-7.
    • (2000) Arthritis Rheum. , vol.43 , pp. 30-37
    • MacGregor, A.J.1    Snieder, H.2    Rigby, A.S.3    Koskenvuo, M.4    Kaprio, J.5    Aho, K.6
  • 2
    • 0033869054 scopus 로고    scopus 로고
    • The prognostic value of anti-cyclic citrullinated peptide antibody in patients with recent-onset rheumatoid arthritis
    • Kroot EJ, de Jong BA, van Leeuwen MA, Swinkels H, van den Hoogen FH, van't Hof M, et al. The prognostic value of anti-cyclic citrullinated peptide antibody in patients with recent-onset rheumatoid arthritis. Arthritis Rheum. 2000;43:1831-5.
    • (2000) Arthritis Rheum. , vol.43 , pp. 1831-1835
    • Kroot, E.J.1    Jong, B.A.2    Leeuwen, M.A.3    Swinkels, H.4    Hoogen, F.H.5    Hof, M.6
  • 3
    • 0031974911 scopus 로고    scopus 로고
    • Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies
    • Schellekens GA, de Jong BA, van den Hoogen FH, van de Putte LB, van Venrooij WJ. Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. J Clin Invest. 1998;101:273-81.
    • (1998) J Clin Invest. , vol.101 , pp. 273-281
    • Schellekens, G.A.1    Jong, B.A.2    Hoogen, F.H.3    Putte, L.B.4    Venrooij, W.J.5
  • 4
    • 0034091322 scopus 로고    scopus 로고
    • The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide
    • Schellekens GA, Visser H, de Jong BA, van den Hoogen FH, Hazes JM, Breedveld FC, et al. The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide. Arthritis Rheum. 2000;43:155-63.
    • (2000) Arthritis Rheum. , vol.43 , pp. 155-163
    • Schellekens, G.A.1    Visser, H.2    Jong, B.A.3    Hoogen, F.H.4    Hazes, J.M.5    Breedveld, F.C.6
  • 5
    • 78549263034 scopus 로고    scopus 로고
    • Anti-citrullinated peptide antibody-negative RA is a genetically distinct subset: a definitive study using only bone-erosive ACPA-negative rheumatoid arthritis
    • Ohmura K, Terao C, Maruya E, Katayama M, Matoba K, Shimada K, et al. Anti-citrullinated peptide antibody-negative RA is a genetically distinct subset: a definitive study using only bone-erosive ACPA-negative rheumatoid arthritis. Rheumatology (Oxford). 2010;49:2298-304.
    • (2010) Rheumatology (Oxford). , vol.49 , pp. 2298-2304
    • Ohmura, K.1    Terao, C.2    Maruya, E.3    Katayama, M.4    Matoba, K.5    Shimada, K.6
  • 6
    • 82755160838 scopus 로고    scopus 로고
    • A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects
    • Terao C, Ohmura K, Kochi Y, Ikari K, Maruya E, Katayama M, et al. A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects. Ann Rheum Dis. 2011;70:2134-9.
    • (2011) Ann Rheum Dis. , vol.70 , pp. 2134-2139
    • Terao, C.1    Ohmura, K.2    Kochi, Y.3    Ikari, K.4    Maruya, E.5    Katayama, M.6
  • 7
    • 65249174519 scopus 로고    scopus 로고
    • Opposing effects of HLA-DRB1*13 alleles on the risk of developing anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis
    • Lundstrom E, Kallberg H, Smolnikova M, Ding B, Ronnelid J, Alfredsson L, et al. Opposing effects of HLA-DRB1*13 alleles on the risk of developing anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis. Arthritis Rheum. 2009;60:924-30.
    • (2009) Arthritis Rheum. , vol.60 , pp. 924-930
    • Lundstrom, E.1    Kallberg, H.2    Smolnikova, M.3    Ding, B.4    Ronnelid, J.5    Alfredsson, L.6
  • 8
    • 29144460980 scopus 로고    scopus 로고
    • Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles
    • Irigoyen P, Lee AT, Wener MH, Li W, Kern M, Batliwalla F, et al. Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles. Arthritis Rheum. 2005;52:3813-8.
    • (2005) Arthritis Rheum. , vol.52 , pp. 3813-3818
    • Irigoyen, P.1    Lee, A.T.2    Wener, M.H.3    Li, W.4    Kern, M.5    Batliwalla, F.6
  • 9
    • 84897992288 scopus 로고    scopus 로고
    • Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity
    • Han B, Diogo D, Eyre S, Kallberg H, Zhernakova A, Bowes J, et al. Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity. Am J Hum Genet. 2014;94:522-32.
    • (2014) Am J Hum Genet. , vol.94 , pp. 522-532
    • Han, B.1    Diogo, D.2    Eyre, S.3    Kallberg, H.4    Zhernakova, A.5    Bowes, J.6
  • 10
    • 77952885768 scopus 로고    scopus 로고
    • A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility
    • Kochi Y, Okada Y, Suzuki A, Ikari K, Terao C, Takahashi A, et al. A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility. Nat Genet. 2010;42:515-9.
    • (2010) Nat Genet. , vol.42 , pp. 515-519
    • Kochi, Y.1    Okada, Y.2    Suzuki, A.3    Ikari, K.4    Terao, C.5    Takahashi, A.6
  • 11
    • 52949100576 scopus 로고    scopus 로고
    • Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population
    • Suzuki A, Yamada R, Kochi Y, Sawada T, Okada Y, Matsuda K, et al. Functional SNPs in CD244 increase the risk of rheumatoid arthritis in a Japanese population. Nat Genet. 2008;40:1224-9.
    • (2008) Nat Genet. , vol.40 , pp. 1224-1229
    • Suzuki, A.1    Yamada, R.2    Kochi, Y.3    Sawada, T.4    Okada, Y.5    Matsuda, K.6
  • 12
    • 79958071902 scopus 로고    scopus 로고
    • Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis-a genome-wide study combined with immunological analyses
    • Terao C, Ohmura K, Katayama M, Takahashi M, Kokubo M, Diop G, et al. Myelin basic protein as a novel genetic risk factor in rheumatoid arthritis-a genome-wide study combined with immunological analyses. PLoS One. 2011;6:e20457.
    • (2011) PLoS One. , vol.6 , pp. e20457
    • Terao, C.1    Ohmura, K.2    Katayama, M.3    Takahashi, M.4    Kokubo, M.5    Diop, G.6
  • 13
    • 79958701491 scopus 로고    scopus 로고
    • The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population
    • Terao C, Yamada R, Ohmura K, Takahashi M, Kawaguchi T, Kochi Y, et al. The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population. Hum Mol Genet. 2011;20:2680-5.
    • (2011) Hum Mol Genet. , vol.20 , pp. 2680-2685
    • Terao, C.1    Yamada, R.2    Ohmura, K.3    Takahashi, M.4    Kawaguchi, T.5    Kochi, Y.6
  • 14
    • 84862809846 scopus 로고    scopus 로고
    • Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population
    • Okada Y, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, et al. Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population. Nat Genet. 2012;44:511-6.
    • (2012) Nat Genet. , vol.44 , pp. 511-516
    • Okada, Y.1    Terao, C.2    Ikari, K.3    Kochi, Y.4    Ohmura, K.5    Suzuki, A.6
  • 17
  • 18
    • 67649880295 scopus 로고    scopus 로고
    • REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis
    • Gregersen PK, Amos CI, Lee AT, Lu Y, Remmers EF, Kastner DL, et al. REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. Nat Genet. 2009;41:820-3.
    • (2009) Nat Genet. , vol.41 , pp. 820-823
    • Gregersen, P.K.1    Amos, C.I.2    Lee, A.T.3    Lu, Y.4    Remmers, E.F.5    Kastner, D.L.6
  • 20
    • 70649086092 scopus 로고    scopus 로고
    • Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk
    • Raychaudhuri S, Thomson BP, Remmers EF, Eyre S, Hinks A, Guiducci C, et al. Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat Genet. 2009;41:1313-8.
    • (2009) Nat Genet. , vol.41 , pp. 1313-1318
    • Raychaudhuri, S.1    Thomson, B.P.2    Remmers, E.F.3    Eyre, S.4    Hinks, A.5    Guiducci, C.6
  • 21
    • 77952888454 scopus 로고    scopus 로고
    • Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
    • Stahl EA, Raychaudhuri S, Remmers EF, Xie G, Eyre S, Thomson BP, et al. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet. 2010;42:508-14.
    • (2010) Nat Genet. , vol.42 , pp. 508-514
    • Stahl, E.A.1    Raychaudhuri, S.2    Remmers, E.F.3    Xie, G.4    Eyre, S.5    Thomson, B.P.6
  • 22
    • 84870531924 scopus 로고    scopus 로고
    • High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
    • Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, et al. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet. 2012;44:1336-40.
    • (2012) Nat Genet. , vol.44 , pp. 1336-1340
    • Eyre, S.1    Bowes, J.2    Diogo, D.3    Lee, A.4    Barton, A.5    Martin, P.6
  • 23
    • 3242713277 scopus 로고    scopus 로고
    • A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
    • Begovich AB, Carlton VE, Honigberg LA, Schrodi SJ, Chokkalingam AP, Alexander HC, et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet. 2004;75:330-7.
    • (2004) Am J Hum Genet. , vol.75 , pp. 330-337
    • Begovich, A.B.1    Carlton, V.E.2    Honigberg, L.A.3    Schrodi, S.J.4    Chokkalingam, A.P.5    Alexander, H.C.6
  • 24
    • 78751705333 scopus 로고    scopus 로고
    • A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis
    • Padyukov L, Seielstad M, Ong RT, Ding B, Ronnelid J, Seddighzadeh M, et al. A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. Ann Rheum Dis. 2011;70:259-65.
    • (2011) Ann Rheum Dis. , vol.70 , pp. 259-265
    • Padyukov, L.1    Seielstad, M.2    Ong, R.T.3    Ding, B.4    Ronnelid, J.5    Seddighzadeh, M.6
  • 25
    • 85027928051 scopus 로고    scopus 로고
    • A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides
    • Bossini-Castillo L, de Kovel C, Kallberg H, van't Slot R, Italiaander A, Coenen M, et al. A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides. Ann Rheum Dis. 2015;74:e15.
    • (2015) Ann Rheum Dis. , vol.74 , pp. e15
    • Bossini-Castillo, L.1    Kovel, C.2    Kallberg, H.3    Slot, R.4    Italiaander, A.5    Coenen, M.6
  • 26
    • 77955463306 scopus 로고    scopus 로고
    • A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis
    • Skinningsrud B, Lie BA, Husebye ES, Kvien TK, Forre O, Flato B, et al. A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis. Ann Rheum Dis. 2010;69:1471-4.
    • (2010) Ann Rheum Dis. , vol.69 , pp. 1471-1474
    • Skinningsrud, B.1    Lie, B.A.2    Husebye, E.S.3    Kvien, T.K.4    Forre, O.5    Flato, B.6
  • 27
    • 84868502721 scopus 로고    scopus 로고
    • Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients
    • Viatte S, Plant D, Bowes J, Lunt M, Eyre S, Barton A, et al. Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients. Ann Rheum Dis. 2012;71:1984-90.
    • (2012) Ann Rheum Dis. , vol.71 , pp. 1984-1990
    • Viatte, S.1    Plant, D.2    Bowes, J.3    Lunt, M.4    Eyre, S.5    Barton, A.6
  • 28
    • 80053552366 scopus 로고    scopus 로고
    • Preferential association of interferon regulatory factor 5 gene variants with seronegative rheumatoid arthritis in 2 Swedish case-control studies
    • Wang C, Kokkonen H, Sandling JK, Johansson M, Seddighzadeh M, Padyukov L, et al. Preferential association of interferon regulatory factor 5 gene variants with seronegative rheumatoid arthritis in 2 Swedish case-control studies. J Rheumatol. 2011;38:2130-2.
    • (2011) J Rheumatol. , vol.38 , pp. 2130-2132
    • Wang, C.1    Kokkonen, H.2    Sandling, J.K.3    Johansson, M.4    Seddighzadeh, M.5    Padyukov, L.6
  • 31
    • 78650860672 scopus 로고    scopus 로고
    • Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records
    • Kurreeman F, Liao K, Chibnik L, Hickey B, Stahl E, Gainer V, et al. Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records. Am J Hum Genet. 2011;88:57-69.
    • (2011) Am J Hum Genet. , vol.88 , pp. 57-69
    • Kurreeman, F.1    Liao, K.2    Chibnik, L.3    Hickey, B.4    Stahl, E.5    Gainer, V.6
  • 32
    • 84863696213 scopus 로고    scopus 로고
    • ACPA-Negative RA Consists of Two Genetically Distinct Subsets Based on RF Positivity in Japanese
    • Terao C, Ohmura K, Ikari K, Kochi Y, Maruya E, Katayama M, et al. ACPA-Negative RA Consists of Two Genetically Distinct Subsets Based on RF Positivity in Japanese. PLoS One. 2012;7:e40067.
    • (2012) PLoS One. , vol.7 , pp. e40067
    • Terao, C.1    Ohmura, K.2    Ikari, K.3    Kochi, Y.4    Maruya, E.5    Katayama, M.6
  • 33
    • 84857781570 scopus 로고    scopus 로고
    • A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1: stratification by autoantibody status in a large UK population
    • Mackie SL, Taylor JC, Martin SG, Wordsworth P, Steer S, Wilson AG, et al. A spectrum of susceptibility to rheumatoid arthritis within HLA-DRB1: stratification by autoantibody status in a large UK population. Genes Immun. 2012;13:120-8.
    • (2012) Genes Immun. , vol.13 , pp. 120-128
    • Mackie, S.L.1    Taylor, J.C.2    Martin, S.G.3    Wordsworth, P.4    Steer, S.5    Wilson, A.G.6
  • 34
    • 84899756990 scopus 로고    scopus 로고
    • Novel risk loci for rheumatoid arthritis in han chinese and congruence with risk variants in europeans
    • Jiang L, Yin J, Ye L, Yang J, Hemani G, Liu AJ, et al. Novel risk loci for rheumatoid arthritis in han chinese and congruence with risk variants in europeans. Arthritis Rheumatol. 2014;66:1121-32.
    • (2014) Arthritis Rheumatol. , vol.66 , pp. 1121-1132
    • Jiang, L.1    Yin, J.2    Ye, L.3    Yang, J.4    Hemani, G.5    Liu, A.J.6
  • 35
    • 0023945481 scopus 로고
    • The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
    • Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988;31:315-24.
    • (1988) Arthritis Rheum. , vol.31 , pp. 315-324
    • Arnett, F.C.1    Edworthy, S.M.2    Bloch, D.A.3    McShane, D.J.4    Fries, J.F.5    Cooper, N.S.6
  • 36
    • 77956055481 scopus 로고    scopus 로고
    • 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative
    • Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham 3rd CO, et al. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum. 2010;62:2569-81.
    • (2010) Arthritis Rheum. , vol.62 , pp. 2569-2581
    • Aletaha, D.1    Neogi, T.2    Silman, A.J.3    Funovits, J.4    Felson, D.T.5    Bingham, C.O.6
  • 38
    • 20944434679 scopus 로고    scopus 로고
    • A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities
    • Kochi Y, Yamada R, Suzuki A, Harley JB, Shirasawa S, Sawada T, et al. A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities. Nat Genet. 2005;37:478-85.
    • (2005) Nat Genet. , vol.37 , pp. 478-485
    • Kochi, Y.1    Yamada, R.2    Suzuki, A.3    Harley, J.B.4    Shirasawa, S.5    Sawada, T.6
  • 39
    • 78049329814 scopus 로고    scopus 로고
    • Association analyses identify six new psoriasis susceptibility loci in the Chinese population
    • Sun LD, Cheng H, Wang ZX, Zhang AP, Wang PG, Xu JH, et al. Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet. 2010;42:1005-9.
    • (2010) Nat Genet. , vol.42 , pp. 1005-1009
    • Sun, L.D.1    Cheng, H.2    Wang, Z.X.3    Zhang, A.P.4    Wang, P.G.5    Xu, J.H.6
  • 40
    • 59249099537 scopus 로고    scopus 로고
    • A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease
    • Burgner D, Davila S, Breunis WB, Ng SB, Li Y, Bonnard C, et al. A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease. PLoS Genet. 2009;5:e1000319.
    • (2009) PLoS Genet. , vol.5 , pp. e1000319
    • Burgner, D.1    Davila, S.2    Breunis, W.B.3    Ng, S.B.4    Li, Y.5    Bonnard, C.6
  • 42
    • 84865119738 scopus 로고    scopus 로고
    • CSMD1 exhibits antitumor activity in A375 melanoma cells through activation of the Smad pathway
    • Tang MR, Wang YX, Guo S, Han SY, Wang D. CSMD1 exhibits antitumor activity in A375 melanoma cells through activation of the Smad pathway. Apoptosis. 2012;17:927-37.
    • (2012) Apoptosis. , vol.17 , pp. 927-937
    • Tang, M.R.1    Wang, Y.X.2    Guo, S.3    Han, S.Y.4    Wang, D.5
  • 43
    • 33646021647 scopus 로고    scopus 로고
    • CSMD1 is a novel multiple domain complement-regulatory protein highly expressed in the central nervous system and epithelial tissues
    • Kraus DM, Elliott GS, Chute H, Horan T, Pfenninger KH, Sanford SD, et al. CSMD1 is a novel multiple domain complement-regulatory protein highly expressed in the central nervous system and epithelial tissues. J Immunol. 2006;176:4419-30.
    • (2006) J Immunol. , vol.176 , pp. 4419-4430
    • Kraus, D.M.1    Elliott, G.S.2    Chute, H.3    Horan, T.4    Pfenninger, K.H.5    Sanford, S.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.