Biodegradable poly (lactic-co-glycolic acid)-polyethylene glycol nanocapsules: An efficient carrier for improved solubility, bioavailability, and anticancer property of lutein

Journal of Pharmaceutical Sciences

Volumn 104, Issue 6, 2015, Pages 2085-2093

  Arunkumar, Ranganathan ^a   Prashanth, Keelara Veerappa Harish ^a   Manabe, Yuki ^b   Hirata, Takashi ^b   Sugawara, Tatsuya ^b   Dharmesh, Shylaja Mallaiah ^a   Baskaran, Vallikannan ^a  

^a CENTRAL FOOD TECHNOLOGICAL RESEARCH INSTITUTE   (India)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

antioxidants; bioavailability; biodegradable polymers; nanocapsules; pharmacokinetics; poly(lactic glycolic) acid (PLGA or PLA); polymeric drug carrier; poorly water soluble drugs; X ray powder diffractometry

Indexed keywords

MACROGOL; NANOCAPSULE; POLY(LACTIC CO GLYCOLIC ACID)POLYETHYLENE GLYCOL NANOCAPSULE; POLYGLACTIN; UNCLASSIFIED DRUG; XANTHOPHYLL; ANTINEOPLASTIC AGENT; LACTIC ACID; MACROGOL DERIVATIVE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL EXPERIMENT; ANTIPROLIFERATIVE ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CHEMICAL INTERACTION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG SOLUBILITY; HUMAN; HUMAN CELL; HYDROGEN BOND; INFRARED SPECTROSCOPY; LIGHT SCATTERING; MALE; MOUSE; NONHUMAN; POSTPRANDIAL STATE; SCANNING ELECTRON MICROSCOPY; X RAY DIFFRACTION; ANIMAL; BIOAVAILABILITY; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; DRUG STABILITY; HEPG2 CELL LINE; NEOPLASMS; SOLUBILITY; TAGETES;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOLOGICAL AVAILABILITY; CELL PROLIFERATION; DRUG STABILITY; HEP G2 CELLS; HUMANS; LACTIC ACID; LUTEIN; MALE; MICE; NANOCAPSULES; NEOPLASMS; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; SOLUBILITY; TAGETES;

EID: 84929224428     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24436     Document Type: Article

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