Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection

Chemistry and Biology

Volumn 21, Issue 8, 2014, Pages 977-987

  Festa, Richard A ^a   Helsel, Marian E ^b   Franz, Katherine J ^b   Thiele, Dennis J ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 QUINOLINOL; ANTIINFECTIVE AGENT; COPPER; IONOPHORE; OXYGEN DERIVATIVE; PEROXIDE; QBP; UNCLASSIFIED DRUG; ANTIFUNGAL AGENT; ORGANOMETALLIC COMPOUND;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMICROBIAL ACTIVITY; ARTICLE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DRUG BIOAVAILABILITY; DRUG DETOXIFICATION; FEMALE; FUNGICIDAL ACTIVITY; IMMUNOCOMPETENT CELL; INNATE IMMUNITY; LUNG INFECTION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PHAGOLYSOSOME; PRIORITY JOURNAL; RESPIRATORY BURST; ANIMAL; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CRYPTOCOCCOSIS; DOSE RESPONSE; DRUG EFFECTS; FILOBASIDIELLA; IMMUNOLOGY; MACROPHAGE; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

FILOBASIDIELLA NEOFORMANS; PROCHELATOR;

ANIMALS; ANTIFUNGAL AGENTS; CELLS, CULTURED; COPPER; CRYPTOCOCCOSIS; CRYPTOCOCCUS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; IMMUNITY, INNATE; MACROPHAGES; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84929177536     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.06.009     Document Type: Article

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