Overexpression of IL-15 promotes tumor destruction via NK1.1+ cells in a spontaneous breast cancer model

BMC Cancer

Volumn 15, Issue 1, 2015, Pages

  Gillgrass, Amy E ^a   Chew, Marianne V ^a   Krneta, Tamara ^a   Ashkar, Ali A ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Breast cancer; CD8 T cells; IL 15; NK cells; NK1.1

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 18; KLRB1C PROTEIN, MOUSE; LY ANTIGEN; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY B;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER SURVIVAL; CARCINOGENESIS; CD3+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DEATH; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; LUNG METASTASIS; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC INFILTRATION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSGENIC MOUSE; TUMOR CELL DESTRUCTION; TUMOR GROWTH; ANIMAL; C57BL MOUSE; EXPERIMENTAL MAMMARY NEOPLASM; FEMALE; GENETICS; IMMUNOLOGY; LUNG TUMOR; METABOLISM; PATHOLOGY; SECONDARY; TUMOR CELL LINE;

ANIMALS; ANTIGENS, LY; CELL LINE, TUMOR; FEMALE; HUMANS; INTERLEUKIN-15; KILLER CELLS, NATURAL; LUNG NEOPLASMS; LYMPHOCYTE ACTIVATION; MAMMARY NEOPLASMS, ANIMAL; MICE, INBRED C57BL; MICE, KNOCKOUT; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY B;

EID: 84929177305     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1264-3     Document Type: Article

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