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Volumn 31, Issue 7, 2015, Pages 986-990

Promiscuous mRNA splicing under the control of AIRE in medullary thymic epithelial cells

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; ISOPROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR;

EID: 84929144058     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/btu785     Document Type: Article
Times cited : (18)

References (26)
  • 1
    • 73149115486 scopus 로고    scopus 로고
    • AIRE's partners in the molecular control of immunological tolerance
    • Abramson, J. et al. (2010) AIRE's partners in the molecular control of immunological tolerance. Cell, 140, 123-135.
    • (2010) Cell , vol.140 , pp. 123-135
    • Abramson, J.1
  • 2
    • 84861656218 scopus 로고    scopus 로고
    • Thymic epithelial cells: Working class heroes for T cell development and repertoire selection
    • Anderson, G. and Takahama, Y. (2012) Thymic epithelial cells: working class heroes for T cell development and repertoire selection. Trends Immunol., 33, 256-263.
    • (2012) Trends Immunol. , vol.33 , pp. 256-263
    • Anderson, G.1    Takahama, Y.2
  • 3
    • 0037112047 scopus 로고    scopus 로고
    • Projection of an immunological self shadow within the thymus by the AIRE protein
    • Anderson, M.S. et al. (2002) Projection of an immunological self shadow within the thymus by the AIRE protein. Science, 298, 1395-1401.
    • (2002) Science , vol.298 , pp. 1395-1401
    • Anderson, M.S.1
  • 4
    • 84907031404 scopus 로고    scopus 로고
    • Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis
    • Bock, L.D. et al. (2014) Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis. J. Immunol., 193, 2147-2156.
    • (2014) J. Immunol. , vol.193 , pp. 2147-2156
    • Bock, L.D.1
  • 5
    • 84905049901 scopus 로고    scopus 로고
    • Trimmomatic: A flexible trimmer for illumina sequence data
    • Bolger, A.M. et al. (2014) Trimmomatic: a flexible trimmer for illumina sequence data. Bioinformatics, 30, 2114-2120.
    • (2014) Bioinformatics , vol.30 , pp. 2114-2120
    • Bolger, A.M.1
  • 6
    • 0035171545 scopus 로고    scopus 로고
    • Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
    • Derbinski, J. et al. (2001) Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat. Immunol., 2, 1032-1039.
    • (2001) Nat. Immunol. , vol.2 , pp. 1032-1039
    • Derbinski, J.1
  • 7
    • 22344449972 scopus 로고    scopus 로고
    • Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels
    • Derbinski, J. et al. (2005) Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J. Exp. Med., 202, 33-45.
    • (2005) J. Exp. Med. , vol.202 , pp. 33-45
    • Derbinski, J.1
  • 8
    • 0027424442 scopus 로고
    • Specific commitment of different pre-mRNAs to splicing by single SR proteins
    • Fu, X.D. (1993) Specific commitment of different pre-mRNAs to splicing by single SR proteins. Nature, 365, 82-85.
    • (1993) Nature , vol.365 , pp. 82-85
    • Fu, X.D.1
  • 9
    • 84855995571 scopus 로고    scopus 로고
    • Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells
    • Giraud, M. et al. (2012) Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells. Proc. Natl Acad. Sci. USA, 109, 535-540.
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 535-540
    • Giraud, M.1
  • 10
    • 0033984067 scopus 로고    scopus 로고
    • Shaping of the autoreactive t-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells
    • Klein, L. et al. (2000) Shaping of the autoreactive t-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells. Nat. Med., 6, 56-61.
    • (2000) Nat. Med. , vol.6 , pp. 56-61
    • Klein, L.1
  • 11
    • 72949104779 scopus 로고    scopus 로고
    • Antigen presentation in the thymus for positive selection and central tolerance induction
    • Klein, L. et al. (2009) Antigen presentation in the thymus for positive selection and central tolerance induction. Nat. Rev. Immunol., 9, 833-844.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 833-844
    • Klein, L.1
  • 12
    • 49449116959 scopus 로고    scopus 로고
    • The splicing factor SC35 has an active role in transcriptional elongation
    • Lin, S. et al. (2008) The splicing factor SC35 has an active role in transcriptional elongation. Nat. Struct. Mol. Biol., 15, 819-826.
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 819-826
    • Lin, S.1
  • 13
    • 84871436996 scopus 로고    scopus 로고
    • Evolutionary dynamics of gene and isoform regulation in mammalian tissues
    • Merkin, J. et al. (2012) Evolutionary dynamics of gene and isoform regulation in mammalian tissues. Science, 338, 1593-1599.
    • (2012) Science , vol.338 , pp. 1593-1599
    • Merkin, J.1
  • 14
    • 9644254186 scopus 로고    scopus 로고
    • Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes
    • Ng, B. et al. (2004) Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes. J. Allergy Clin. Immunol., 114, 1463-1470.
    • (2004) J. Allergy Clin. Immunol. , vol.114 , pp. 1463-1470
    • Ng, B.1
  • 15
    • 37549060329 scopus 로고    scopus 로고
    • AIRE recruits p-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells
    • Oven, I. et al. (2007) AIRE recruits p-TEFb for transcriptional elongation of target genes in medullary thymic epithelial cells. Mol. Cell. Biol., 27, 8815-8823.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 8815-8823
    • Oven, I.1
  • 16
    • 1542269618 scopus 로고    scopus 로고
    • Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED): A model disease to study molecular aspects of endocrine autoimmunity
    • Peterson, P. et al. (2004) Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED): a model disease to study molecular aspects of endocrine autoimmunity. Clin. Exp. Immunol., 135, 348-357.
    • (2004) Clin. Exp. Immunol. , vol.135 , pp. 348-357
    • Peterson, P.1
  • 17
    • 75249101203 scopus 로고    scopus 로고
    • ARH: Predicting splice variants from genome-wide data with modified entropy
    • Rasche, A. and Herwig, R. (2010) ARH: predicting splice variants from genome-wide data with modified entropy. Bioinformatics, 26, 84-90.
    • (2010) Bioinformatics , vol.26 , pp. 84-90
    • Rasche, A.1    Herwig, R.2
  • 18
    • 41849110528 scopus 로고    scopus 로고
    • Entropy measures quantify global splicing disorders in cancer
    • Ritchie, W. et al. (2008) Entropy measures quantify global splicing disorders in cancer. PLoS Comput. Biol., 4, e1000011.
    • (2008) PLoS Comput. Biol. , vol.4 , pp. e1000011
    • Ritchie, W.1
  • 19
    • 33745516115 scopus 로고    scopus 로고
    • Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium
    • Rossi, S.W. et al. (2006) Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium. Nature, 441, 988-991.
    • (2006) Nature , vol.441 , pp. 988-991
    • Rossi, S.W.1
  • 20
    • 84878730343 scopus 로고    scopus 로고
    • Transcriptome sequencing of neonatal thymic epithelial cells
    • St-Pierre, C. et al. (2013) Transcriptome sequencing of neonatal thymic epithelial cells. Sci. Rep., 3, 1860.
    • (2013) Sci. Rep. , vol.3 , pp. 1860
    • St-Pierre, C.1
  • 21
    • 46049099789 scopus 로고    scopus 로고
    • Exon and junction microarrays detect widespread mouse strain- and sex-bias expression differences
    • Su, W-L. et al. (2008) Exon and junction microarrays detect widespread mouse strain- and sex-bias expression differences. BMC Genomics, 9, 273.
    • (2008) BMC Genomics , vol.9 , pp. 273
    • Su, W.-L.1
  • 22
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-Seq
    • Trapnell, C. et al. (2009) TopHat: discovering splice junctions with RNA-Seq. Bioinformatics, 25, 1105-1111.
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1
  • 23
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • Trapnell, C. et al. (2010) Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat. Biotechnol., 28, 511-515.
    • (2010) Nat. Biotechnol. , vol.28 , pp. 511-515
    • Trapnell, C.1
  • 24
    • 75349083571 scopus 로고    scopus 로고
    • Identification and functional analyses of 11 769 full-length human cDNAs focused on alternative splicing
    • Wakamatsu, A. et al. (2009) Identification and functional analyses of 11 769 full-length human cDNAs focused on alternative splicing. DNA Res., 16, 371-383.
    • (2009) DNA Res. , vol.16 , pp. 371-383
    • Wakamatsu, A.1
  • 25
    • 0036712421 scopus 로고    scopus 로고
    • Genome-wide detection of tissue-specific alternative splicing in the human transcriptome
    • Xu, Q. et al. (2002) Genome-wide detection of tissue-specific alternative splicing in the human transcriptome. Nucleic Acids Res., 30, 3754-3766.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 3754-3766
    • Xu, Q.1
  • 26
    • 80054065566 scopus 로고    scopus 로고
    • Patient mutation in AIRE disrupts p-TEFb binding and target gene transcription
    • Zumer, K. et al. (2011) Patient mutation in AIRE disrupts p-TEFb binding and target gene transcription. Nucleic Acids Res., 39, 7908-7919.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 7908-7919
    • Zumer, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.