Non-invasive assessment of liver fibrosis in C282Y homozygous HFE hemochromatosis

Liver International

Volumn 35, Issue 6, 2015, Pages 1731-1738

  Legros, Ludivine ^a   Bardou Jacquet, Edouard ^a,b   Latournerie, Marianne ^a   Guillygomarc'h, Anne ^a   Turlin, Bruno ^a,b   Le Lan, Caroline ^a   Désille, Yoann ^a   Lainé, Fabrice ^c   Moirand, Romain ^a,b   Brissot, Pierre ^a,b   Deugnier, Yves ^a,b   Guyader, Dominique ^a,b  

^a RENNES UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Cirrhosis; Hyaluronic acid; Liver fibrosis; Serum ferritin; Transient elastography

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ASPARTATE AMINOTRANSFERASE; FERRITIN; GAMMA GLUTAMYLTRANSFERASE; HFE PROTEIN; HYALURONIC ACID; AMINOTRANSFERASE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL CONSUMPTION; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHRONIC HEPATITIS C; COHORT ANALYSIS; DIAGNOSTIC ACCURACY; DISEASE SEVERITY; ELASTOGRAPHY; FEMALE; FERRITIN BLOOD LEVEL; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HEMOCHROMATOSIS; HEPATOMEGALY; HOMOZYGOTE; HUMAN; HYPERTRANSAMINASEMIA; LIVER BIOPSY; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OBESITY; OBSERVATIONAL STUDY; PATHOLOGIST; PROSPECTIVE STUDY; PROTHROMBIN TIME; STEATOSIS; THROMBOCYTE COUNT; TRANSIENT ELASTOGRAPHY; BIOPSY; BLOOD; COMPLICATION; GENETICS; LIVER; LIVER CIRRHOSIS; MUTATION; PATHOLOGY; PROCEDURES; RECEIVER OPERATING CHARACTERISTIC;

ADULT; BIOPSY; ELASTICITY IMAGING TECHNIQUES; FEMALE; FERRITINS; HEMOCHROMATOSIS; HOMOZYGOTE; HUMANS; HYALURONIC ACID; LIVER; LIVER CIRRHOSIS; MALE; MIDDLE AGED; MUTATION; PROSPECTIVE STUDIES; ROC CURVE; TRANSAMINASES;

EID: 84929131683     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12762     Document Type: Article

References (34)

1. Brissot P, Bardou-Jacquet E, Jouanolle AM, Loreal O. Iron disorders of genetic origin: a changing world. Trends Mol Med 2011; 17: 707-13.
2. Brissot P, Moirand R, Jouanolle AM, et al. A genotypic study of 217 unrelated probands diagnosed as "genetic hemochromatosis" on "classical" phenotypic criteria. J Hepatol 1999; 30: 588-93.
3. Wood MJ, Powell LW, Ramm GA. Environmental and genetic modifiers of the progression to fibrosis and cirrhosis in hemochromatosis. Blood 2008; 111: 4456-62.
4. Ramm GA, Ruddell RG. Iron homeostasis, hepatocellular injury, and fibrogenesis in hemochromatosis: the role of inflammation in a noninflammatory liver disease. Semin Liver Dis 2010; 30: 271-87.
5. Deugnier YM, Guyader D, Crantock L, et al. Primary liver cancer in genetic hemochromatosis: a clinical, pathological, and pathogenetic study of 54 cases. Gastroenterology 1993; 104: 228-34.
6. Deugnier Y M, Charalambous P, Le Quilleuc D, et al. Preneoplastic significance of hepatic iron-free foci in genetic hemochromatosis: a study of 185 patients. Hepatology (Baltimore, Md) 1993; 18: 1363-9.
7. Piccinino F, Sagnelli E, Pasquale G, Giusti G. Complications following percutaneous liver biopsy. a multicentre retrospective study on 68276 biopsies. J Hepatol 1986; 2: 165-73.
8. Bedossa P, Dargere D, Paradis V. Sampling variability of liver fibrosis in chronic hepatitis C. Hepatology 2003; 38: 1449-57.
9. Bacon BR, Adams PC, Kowdley KV, Powell LW, Tavill AS. Diagnosis and management of hemochromatosis: 2011 practice guideline by the American Association for the Study of Liver Diseases. Hepatology 2011; 54: 328-43.
10. Guyader D, Jacquelinet C, Moirand R, et al. Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis. Gastroenterology 1998; 115: 929-36.
11. Crawford DH, Murphy TL, Ramm LE, et al. Serum hyaluronic acid with serum ferritin accurately predicts cirrhosis and reduces the need for liver biopsy in C282Y hemochromatosis. Hepatology 2009; 49: 418-25.
12. Castera L, Vergniol J, Foucher J, et al. Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C. Gastroenterology 2005; 128: 343-50.
13. EASL Clinical Practice Guidelines. Management of hepatitis C virus infection. J Hepatol 2011; 55: 245-64.
14. Marcellin P, Ziol M, Bedossa P, et al. Non-invasive assessment of liver fibrosis by stiffness measurement in patients with chronic hepatitis B. Liver Int 2009; 29: 242-7.
15. Wong VW, Vergniol J, Wong GL, et al. Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease. Hepatology 2010; 51: 454-62.
16. Corpechot C, El Naggar A, Poujol-Robert A, et al. Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC. Hepatology 2006; 43: 1118-24.
17. Bardou-Jacquet E, Legros L, Soro D, et al. Effect of alcohol consumption on liver stiffness measured by transient elastography. World J Gastroenterol 2013; 19: 516-22.
18. Mirault T, Lucidarme D, Turlin B, et al. Non-invasive assessment of liver fibrosis by transient elastography in post transfusional iron overload. Eur J Haematol 2008; 80: 337-40.
19. Adhoute X, Foucher J, Laharie D, et al. Diagnosis of liver fibrosis using FibroScan and other noninvasive methods in patients with hemochromatosis: a prospective study. Gastroenterol Clin Biol 2008; 32: 180-7.
20. Jazwinska EC, Cullen LM, Busfield F, et al. Haemochromatosis and HLA-H. Nat Genet 1996; 14: 249-51.
21. Kleiner DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005; 41: 1313-21.
22. Falize L, Guillygomarc'h A, Perrin M, et al. Reversibility of hepatic fibrosis in treated genetic hemochromatosis: a study of 36 cases. Hepatology 2006; 44: 472-7.
23. Fracanzani AL, Piperno A, Valenti L, et al. Hemochromatosis in Italy in the last 30 years: role of genetic and acquired factors. Hepatology 2010; 51: 501-10.
24. Beaton M, Guyader D, Deugnier Y, et al. Noninvasive prediction of cirrhosis in C282Y-linked hemochromatosis. Hepatology 2002; 36: 673-8.
25. Morrison ED, Brandhagen DJ, Phatak PD, et al. Serum ferritin level predicts advanced hepatic fibrosis among U.S. patients with phenotypic hemochromatosis. Ann Intern Med 2003; 138: 627-33.
26. Arena U, Vizzutti F, Abraldes JG, et al. Reliability of transient elastography for the diagnosis of advanced fibrosis in chronic hepatitis C. Gut 2008; 57: 1288-93.
27. Ziol M, Handra-Luca A, Kettaneh A, et al. Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C. Hepatology 2005; 41: 48-54.
28. Nahon P, Kettaneh A, Tengher-Barna I, et al. Assessment of liver fibrosis using transient elastography in patients with alcoholic liver disease. J Hepatol 2008; 49: 1062-8.
29. Gelsi E, Dainese R, Truchi R, et al. Effect of detoxification on liver stiffness assessed by Fibroscan(R) in alcoholic patients. Alcohol Clin Exp Res 2011; 35: 566-70.
30. Boursier J, de ledinghen V, Sturm N, et al. Precise evaluation of liver histology by compterized morphometry shows that steatosis influence liver stiffness measured by transient elastography in chronic hepatitis C. J Gastroenterol 2014; 49: 527-37.
31. Castera L, Foucher J, Bernard PH, et al. Pitfalls of liver stiffness measurement: a 5-year prospective study of 13 369 examinations. Hepatology 2010; 51: 828-35.
32. Myers RP, Pomier-Layrargues G, Kirsch R, et al. Feasibility and diagnostic performance of the FibroScan XL probe for liver stiffness measurement in overweight and obese patients. Hepatology 2012; 55: 199-208.
33. Lucidarme D, Foucher J, Le Bail B, et al. Factors of accuracy of transient elastography (fibroscan) for the diagnosis of liver fibrosis in chronic hepatitis C. Hepatology 2009; 49: 1083-9.
34. Boursier J, Zarski JP, De Ledinghen V, et al. Determination of reliability criteria for liver stiffness evaluation by transient elastography. Hepatology 2013; 57: 1182-91.