Chronic Trichuris muris infection in C57BL/6 mice causes significant changes in host microbiota and metabolome: Effects reversed by pathogen clearance

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Houlden, Ashley ^a   Hayes, Kelly S ^a   Bancroft, Allison J ^a   Worthington, John J ^a   Wang, Ping ^a   Grencis, Richard K ^a   Roberts, Ian S ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CARBOHYDRATE; MEBENDAZOLE; POLYSACCHARIDE; ANTHELMINTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTEROIDETES; C57BL 6 MOUSE; CELL POPULATION; CONTROLLED STUDY; DIGESTION; DIGESTIVE FUNCTION; FECES MICROFLORA; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; INFECTION; INTESTINE FLORA; MALE; METABOLOME; METABOLOMICS; MICROBIAL COMMUNITY; MICROBIAL DIVERSITY; MOUSE; NEMATODIASIS; NONHUMAN; PARABACTEROIDES; PATHOGEN CLEARANCE; PATHOPHYSIOLOGY; POPULATION ABUNDANCE; PREVOTELLA; PYROSEQUENCING; SPECIES COMPOSITION; TREATMENT DURATION; TRICHURIS MURIS; TRICHURIS MURIS INFECTION; WEIGHT GAIN; ANIMAL; BACTERIUM; BIODIVERSITY; C57BL MOUSE; CHRONIC DISEASE; CLASSIFICATION; DISEASE MODEL; DRUG EFFECTS; GENETICS; HOST PARASITE INTERACTION; IMMUNOLOGY; METABOLISM; METAGENOME; MICROBIOLOGY; MICROFLORA; PARASITOLOGY; PROCEDURES; TIME FACTOR; TRICHURIASIS; TRICHURIS;

ANIMALIA; BACTEROIDETES; MUS; PREVOTELLA; TRICHURIS; TRICHURIS MURIS; VERMES;

ANIMALS; ANTHELMINTICS; BACTERIA; BIODIVERSITY; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; HOST-PARASITE INTERACTIONS; METABOLOME; METABOLOMICS; METAGENOME; MICE; MICE, INBRED C57BL; MICROBIOTA; TIME FACTORS; TRICHURIASIS; TRICHURIS;

EID: 84929103328     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0125945     Document Type: Article

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