CD36 inhibition prevents lipid accumulation and contractile dysfunction in rat cardiomyocytes

Biochemical Journal

Volumn 448, Issue 1, 2012, Pages 43-53

  Angin, Yeliz ^a   Steinbusch, Laura K M ^a   Simons, Peter J ^b   Greulich, Sabrina ^c   Hoebers, Nicole T H ^a   Douma, Kim ^a   Van Zandvoort, Marc A M J ^a   Coumans, Will A ^a   Wijnen, Wino ^a   Diamant, Michaela ^d   Ouwens, D Margriet ^c   Glatz, Jan F C ^a   Luiken, Joost J F P ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b BIOCEROS   (Netherlands)

^c LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cardiac metabolism; CD36; Diabetes; Insulin resistance; Lipid accumulation

Indexed keywords

CD36 ANTIGEN; GLUCOSE; INSULIN; PALMITIC ACID; TRIACYLGLYCEROL;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME PHOSPHORYLATION; GLUCOSE TRANSPORT; HEART CONTRACTILE DYSFUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE METABOLISM; IMMUNOCHEMISTRY; INSULIN RESISTANCE; LIPID STORAGE; MYOCARDIAL DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOMERE; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; ANTIGENS, CD36; BIOLOGICAL TRANSPORT; CALCIUM SIGNALING; CELLS, CULTURED; DIABETIC CARDIOMYOPATHIES; FATTY ACIDS; GLUCOSE; INSULIN; INSULIN RESISTANCE; MALE; MITOCHONDRIA, HEART; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PALMITATES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, INBRED LEW; SARCOLEMMA; SARCOMERES; SIGNAL TRANSDUCTION; TRIGLYCERIDES;

EID: 84867784655     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120060     Document Type: Article

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