Coinfection with blood-stage Plasmodium promotes systemic type I interferon production during pneumovirus infection but impairs inflammation and viral control in the lung

Clinical and Vaccine Immunology

Volumn 22, Issue 5, 2015, Pages 477-483

  Edwards, Chelsea L ^a   Zhang, Vivian ^b   Werder, Rhiannon B ^b   Best, Shannon E ^a   Sebina, Ismail ^a   James, Kylie R ^a   Faleiro, Rebecca J ^a   De Labastida Rivera, Fabian ^a   Amante, Fiona H ^a   Engwerda, Christian R ^a,b   Phipps, Simon ^b   Haque, Ashraful ^a,b  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR; IL10 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; FEMALE; INTERFERON PRODUCTION; MIXED INFECTION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PARASITEMIA; PLASMODIUM CHABAUDI INFECTION; PNEUMOVIRUS INFECTION; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION; SPLENOMEGALY; VIRAL RESPIRATORY TRACT INFECTION; VIRUS LOAD; VIRUS REPLICATION; WEIGHT REDUCTION; ANIMAL; BLOOD; COMPLICATION; DISEASE MODEL; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNOLOGY; INFLAMMATION; LUNG; MALARIA; PARASITOLOGY; PATHOGENICITY; PHYSIOLOGY; PLASMODIUM CHABAUDI; PNEUMOVIRUS; VIRAL BRONCHIOLITIS; VIROLOGY;

ANIMALS; BRONCHIOLITIS, VIRAL; COINFECTION; DISEASE MODELS, ANIMAL; FEMALE; INFLAMMATION; INTERFERON-BETA; INTERLEUKIN-10; LUNG; MALARIA; PLASMODIUM CHABAUDI; PNEUMOVIRUS; PNEUMOVIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; VIRAL LOAD; WEIGHT LOSS;

EID: 84929076736     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00051-15     Document Type: Article

References (25)

1. Nair H, Nokes DJ, Gessner BD, Dherani M, Madhi SA, Singleton RJ, O'Brien KL, Roca A, Wright PF, Bruce N, Chandran A, Theodoratou E, Sutanto A, Sedyaningsih ER, Ngama M, Munywoki PK, Kartasasmita C, Simoes EA, Rudan I, Weber MW, Campbell H. 2010. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet 375:1545-1555. http://dx.doi.org/10.1016/S0140-6736 (10) 60206-1.
2. WHO. 2012. WHO Global Malaria Programme: world malaria report 2012. World Health Organization, Geneva, Switzerland. http://www.who.int/malaria/publications/world-malaria-report-2012/wmr2012-no-profiles.pdf?ua= 1.
3. WHO. 2013. WHO Global Malaria Programme: world malaria report 2013. World Health Organization, Geneva, Switzerland. http://www.who.int/malaria/publications/world-malaria-report-2013/wmr2013-no-profiles.pdf?ua= 1.
4. Haynes AK, Manangan AP, Iwane MK, Sturm-Ramirez K, Homaira N, Brooks WA, Luby S, Rahman M, Klena JD, Zhang Y, Yu H, Zhan F, Dueger E, Mansour AM, Azazzy N, McCracken JP, Bryan JP, Lopez MR, Burton DC, Bigogo G, Breiman RF, Feikin DR, Njenga K, Montgomery J, Cohen AL, Moyes J, Pretorius M, Cohen C, Venter M, Chittaganpitch M, Thamthitiwat S, Sawatwong P, Baggett HC, Luber G, Gerber SI. 2013. Respiratory syncytial virus circulation in seven countries with Global Disease Detection Regional Centers. J Infect Dis 208(Suppl 3):S246-S254. http://dx.doi.org/10.1093/infdis/jit515.
5. Feasey NA, Dougan G, Kingsley RA, Heyderman RS, Gordon MA. 2012. Invasive non-typhoidal Salmonella disease: an emerging and neglected tropical disease in Africa. Lancet 379:2489-2499. http://dx.doi.org/10.1016/S0140-6736 (11) 61752-2.
6. Cunnington AJ, De Souza JB, Walther M, Riley EM. 2012. Malaria impairs resistance to Salmonella through heme- and heme oxygenasedependent dysfunctional granulocyte mobilization. Nat Med 18:120-127. http://dx.doi.org/10.1038/nm.2601.
7. Lokken KL, Mooney JP, Butler BP, Xavier MN, Chau JY, Schaltenberg N, Begum RH, Muller W, Luckhart S, Tsolis RM. 2014. Malaria parasite infection compromises control of concurrent systemic nontyphoidal Salmonella infection via IL-10-mediated alteration of myeloid cell function. PLoS Pathog 10:e1004049. http://dx.doi.org/10.1371/journal.ppat.1004049.
8. Mooney JP, Butler BP, Lokken KL, Xavier MN, Chau JY, Schaltenberg N, Dandekar S, George MD, Santos RL, Luckhart S, Tsolis RM. 2014. The mucosal inflammatory response to non-typhoidal Salmonella in the intestine is blunted by IL-10 during concurrent malaria parasite infection. Mucosal Immunol 7:1302-1311. http://dx.doi.org/10.1038/mi.2014.18.
9. Niikura M, Kamiya S, Kita K, Kobayashi F. 2008. Coinfection with nonlethal murine malaria parasites suppresses pathogenesis caused by Plasmodium berghei NK65. J Immunol 180:6877-6884. http://dx.doi.org/10.4049/jimmunol.180.10.6877.
10. Niikura M, Kamiya S, Nakane A, Kita K, Kobayashi F. 2010. IL-10 plays a crucial role for the protection of experimental cerebral malaria by coinfection with non-lethal malaria parasites. Int J Parasitol 40:101-108. http://dx.doi.org/10.1016/j.ijpara.2009.08.009.
11. D'Acremont V, Kilowoko M, Kyungu E, Philipina S, Sangu W, Kahama-Maro J, Lengeler C, Cherpillod P, Kaiser L, Genton B. 2014. Beyond malaria-causes of fever in outpatient Tanzanian children. N Engl J Med 370:809-817. http://dx.doi.org/10.1056/NEJMoa1214482.
12. Davidson S, Kaiko G, Loh Z, Lalwani A, Zhang V, Spann K, Foo SY, Hansbro N, Uematsu S, Akira S, Matthaei KI, Rosenberg HF, Foster PS, Phipps S. 2011. Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway. J Immunol 186:5938-5948. http://dx.doi.org/10.4049/jimmunol.1002635.
13. Apte SH, Groves PL, Roddick JS, P Da Hora V, Doolan DL. 2011. High-throughput multi-parameter flow-cytometric analysis from microquantities of Plasmodium-infected blood. Int J Parasitol 41:1285-1294. http://dx.doi.org/10.1016/j.ijpara.2011.07.010.
14. Haque A, Best SE, Montes De Oca M, James KR, Ammerdorffer A, Edwards CL, De Labastida Rivera F, Amante FH, Bunn PT, Sheel M, Sebina I, Koyama M, Varelias A, Hertzog PJ, Kalinke U, Gun SY, Renia L, Ruedl C, MacDonald KP, Hill GR, Engwerda CR. 2014. Type I IFN signaling in CD8-DCs impairs Th1-dependent malaria immunity. J Clin Invest 124:2483-2496. http://dx.doi.org/10.1172/JCI70698.
15. Klonis N, Crespo-Ortiz MP, Bottova I, Abu-Bakar N, Kenny S, Rosenthal PJ, Tilley L. 2011. Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion. Proc Natl Acad Sci U S A 108:11405-11410. http://dx.doi.org/10.1073/pnas.1104063108.
16. Malleret B, Claser C, Ong AS, Suwanarusk R, Sriprawat K, Howland SW, Russell B, Nosten F, Renia L. 2011. A rapid and robust tricolor flow cytometry assay for monitoring malaria parasite development. Sci Rep 1:118.
17. Phipps S, Lam CE, Kaiko GE, Foo SY, Collison A, Mattes J, Barry J, Davidson S, Oreo K, Smith L, Mansell A, Matthaei KI, Foster PS. 2009. Toll/IL-1 signaling is critical for house dust mite-specific helper T cell type 2 and type 17 [corrected] responses. Am J Respir Crit Care Med 179:883-893. http://dx.doi.org/10.1164/rccm.200806-974OC.
18. Kaiko GE, Loh Z, Spann K, Lynch JP, Lalwani A, Zheng Z, Davidson S, Uematsu S, Akira S, Hayball J, Diener KR, Baines KJ, Simpson JL, Foster PS, Phipps S. 2013. Toll-like receptor 7 gene deficiency and earlylife Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice. J Allergy Clin Immunol 131:1331-1339. http://dx.doi.org/10.1016/j.jaci.2013.02.041.
19. Glineur SF, Bowen AB, Percopo CM, Garcia-Crespo KE, Dyer KD, Ochkur SI, Lee NA, Lee JJ, Domachowske JB, Rosenberg HF. 2014. Sustained inflammation and differential expression of interferons type I and III in PVM-infected interferon-gamma (IFN7) gene-deleted mice. Virology 468-470:140-149. http://dx.doi.org/10.1016/j.virol.2014.07.039.
20. Coban C, Ishii KJ, Kawai T, Hemmi H, Sato S, Uematsu S, Yamamoto M, Takeuchi O, Itagaki S, Kumar N, Horii T, Akira S. 2005. Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J Exp Med 201:19-25. http://dx.doi.org/10.1084/jem.20041836.
21. Wykes MN, Kay JG, Manderson A, Liu XQ, Brown DL, Richard DJ, Wipasa J, Jiang SH, Jones MK, Janse CJ, Waters AP, Pierce SK, Miller LH, Stow JL, Good MF. 2011. Rodent blood-stage Plasmodium survive in dendritic cells that infect naive mice. Proc Natl Acad Sci USA 108:11205-11210. http://dx.doi.org/10.1073/pnas.1108579108.
22. Sharma S, De Oliveira RB, Kalantari P, Parroche P, Goutagny N, Jiang Z, Chan J, Bartholomeu DC, Lauw F, Hall JP, Barber GN, Gazzinelli RT, Fitzgerald KA, Golenbock DT. 2011. Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome. Immunity 35:194-207. http://dx.doi.org/10.1016/j.immuni.2011.05.016.
23. Swiecki M, Wang Y, Vermi W, Gilfillan S, Schreiber RD, Colonna M. 2011. Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo. J Exp Med 208:2367-2374. http://dx.doi.org/10.1084/jem.20110654.
24. Medeiros MM, Da Silva HB, Reis AS, Barboza R, Thompson J, Lima MR, Marinho CR, Tadokoro CE. 2013. Liver accumulation of Plasmodium chabaudi-infected red blood cells and modulation of regulatory T cell and dendritic cell responses. PLoS One 8:e81409. http://dx.doi.org/10.1371/journal.pone.0081409.
25. Haque A, Best SE, Amante FH, Mustafah S, Desbarrieres L, De Labastida F, Sparwasser T, Hill GR, Engwerda CR. 2010. CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivo. PLoS Pathog 6:e1001221. http://dx.doi.org/10.1371/journal.ppat.1001221.