Extracellular Ca2+-dependent enhancement of cytocidal potency of zoledronic acid in human oral cancer cells

European Journal of Pharmacology

Volumn 761, Issue , 2015, Pages 44-54

  Inoue, Sayaka ^a   Arai, Naoya ^b   Tomihara, Kei ^a   Takashina, Michinori ^a   Hattori, Yuichi ^a   Noguchi, Makoto ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b MIE UNIVERSITY   (Japan)

Author keywords

Bisphosphonate; Cytocidal; Extracellular Ca2+; Oral squamous cell carcinoma; Zoledronic acid

Indexed keywords

CISPLATIN; CYTOCHROME C; GEMCITABINE; PROTEIN BAX; ZOLEDRONIC ACID; ANTINEOPLASTIC AGENT; BAX PROTEIN, HUMAN; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; CALCIUM CHELATING AGENT; IMIDAZOLE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CALCIUM TRANSPORT; CANCER INHIBITION; COLON CANCER; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; EXTRACELLULAR CALCIUM; HUMAN; HUMAN CELL; JAW CANCER; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MITOSIS INHIBITION; MOUTH SQUAMOUS CELL CARCINOMA; ORAL CANCER CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; UPREGULATION; BREAST NEOPLASMS; CARCINOMA, SQUAMOUS CELL; CELL PROLIFERATION; COLONIC NEOPLASMS; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECTS; HEAD AND NECK NEOPLASMS; MCF 7 CELL LINE; METABOLISM; MOUTH NEOPLASMS; PATHOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BREAST NEOPLASMS; CALCIUM; CALCIUM CHELATING AGENTS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; CYTOCHROMES C; DIPHOSPHONATES; DOSE-RESPONSE RELATIONSHIP, DRUG; HEAD AND NECK NEOPLASMS; HUMANS; IMIDAZOLES; MCF-7 CELLS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MOUTH NEOPLASMS;

EID: 84929072623     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.04.032     Document Type: Article

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