Instructional review: General orthopaedics silver nanoparticles and their orthopaedic applications

Bone and Joint Journal

Volumn 97-B, Issue 5, 2015, Pages 582-589

  Brennan, S A ^a   Fhoghlú, C Ní ^a   DeVitt, B M ^a   O'Mahony, F J ^a,b   Brabazon, D ^a,c   Walsh, A ^a  

^a OUR LADY OF LOURDES HOSPITAL   (Ireland)

^b Department of Medicine National University of Ireland Cork   (Ireland)

^c DUBLIN CITY UNIVERSITY   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BONE CEMENT; HYDROXYAPATITE; SILVER NANOPARTICLE; NANOPARTICLE; SILVER;

ANTIMICROBIAL ACTIVITY; BIOCOMPATIBILITY; DRUG MANUFACTURE; DRUG MECHANISM; EXTERNAL FIXATOR; HUMAN; MATERIAL COATING; NANOTECHNOLOGY; NONHUMAN; ORTHOPEDICS; OSTEOMYELITIS; PRIORITY JOURNAL; PROSTHESIS INFECTION; PSEUDARTHROSIS; REVIEW; WOUND DRESSING; ADVERSE EFFECTS; ANIMAL; BACTERIAL INFECTIONS; BONE NAIL; DEVICES; MICROBIOLOGY; ORTHOPEDIC SURGERY; POSTOPERATIVE COMPLICATIONS; PROSTHESIS; PROSTHESIS-RELATED INFECTIONS;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; BONE NAILS; DURAPATITE; HUMANS; NANOPARTICLES; ORTHOPEDIC PROCEDURES; POSTOPERATIVE COMPLICATIONS; PROSTHESIS DESIGN; PROSTHESIS-RELATED INFECTIONS; SILVER;

EID: 84929072184     PISSN: 20494394     EISSN: 20494408     Source Type: Journal    
DOI: 10.1302/0301-620X.97B5.33336     Document Type: Review

References (83)

1. Agarwal A, Weis TL, Schurr MJ, et al. Surfaces modified with nanometer-thick silver-impregnated polymeric films that kill bacteria but support growth of mammalian cells. Biomaterials 2010;31:680-690.
2. Sambhy V, MacBride MM, Peterson BR, Sen A. Silver bromide nanoparticle/polymer composites: dual action tunable antimicrobial materials. J Am Chem Soc 2006;128:9798-9808.
3. Cao H, Liu X. Silver nanoparticles-modified films versus biomedical device-associated infections. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2010;2:670-684.
4. Ansari MA, Khan HM, Khan AA, et al. Interaction of silver nanoparticles with Escherichia coli and their cell envelope biomolecules. J Basic Microbiol 2014;54:905-915.
5. Phillips PL, Yang Q, Davis S, et al. Antimicrobial dressing efficacy against mature Pseudomonas aeruginosa biofilm on porcine skin explants. Int Wound J 2013; (Epub ahead of print).
6. Phillips PL, Yang Q, Davis S, et al. Antimicrobial dressing efficacy against mature Pseudomonas aeruginosa biofilm on porcine skin explants. Int Wound J 2013; (Epub ahead of print).:.
7. Nair LS, Laurencin CT. Nanofibers and nanoparticles for orthopaedic surgery applications. J Bone Joint Surg [Am] 2008;90-A(Supp l1):128-131.
8. Chaloupka K, Malam Y, Seifalian AM. Nanosilver as a new generation of nanoproduct in biomedical applications. Trends Biotechnol 2010;28:580-588.
9. Yamanaka M, Hara K, Kudo J. Bactericidal actions of a silver ion solution on Escherichia coli, studied by energy-filtering transmission electron microscopy and proteomic analysis. Appl Environ Microbiol 2005;71:7589-7593.
10. Alt V, Bechert T, Steinrücke P, et al. An in vitro assessment of the antibacterial properties and cytotoxicity of nanoparticulate silver bone cement. Biomaterials 2004;25:4383-4391.
11. Chaloupka K, Malam Y, Seifalian AM. Nanosilver as a new generation of nanoproduct in biomedical applications. Trends Biotechnol 2010;28:580-588.
12. Park HJ, Kim JY, Kim J, et al. Silver-ion-mediated reactive oxygen species generation affecting bactericidal activity. Water Res 2009;43:1027-1032.
13. Percival SL, Bowler PG, Russell D. Bacterial resistance to silver in wound care. J Hosp Infect 2005;60:1-7.
14. Cuin A, Massabni AC, Leite CQ, et al. Synthesis, X-ray structure and antimycobacterial activity of silver complexes with alpha-hydroxycarboxylic acids. J Inorg Biochem 2007;101:291-296.
15. Taglietti A, Arciola CR, D'Agostino A, et al. Antibiofilm activity of a monolayer of silver nanoparticles anchored to an amino-silanized glass surface. Biomaterials 2014;35:1779-1788.
16. Choi O, Deng KK, Kim NJ, et al. The inhibitory effects of silver nanoparticles, silver ions, and silver chloride colloids on microbial growth. Water Res 2008;42:3066-3074.
17. Alt V, Bechert T, Steinrücke P, et al. An in vitro assessment of the antibacterial properties and cytotoxicity of nanoparticulate silver bone cement. Biomaterials 2004;25:4383-4391.
18. Kim JS, Kuk E, Yu KN, et al. Antimicrobial effects of silver nanoparticles. Nanomedicine 2007;3:95-101.
19. Fayaz AM, Balaji K, Girilal M, et al. Biogenic synthesis of silver nanoparticles and their synergistic effect with antibiotics: a study against gram-positive and gram-negative bacteria. Nanomedicine 2010;6:103-109.
20. Dar MA, Ingle A, Rai M. Enhanced antimicrobial activity of silver nanoparticles synthesized by Cryphonectria sp. evaluated singly and in combination with antibiotics. Nanomedicine 2013;9:105-110.
21. Chaloupka K, Malam Y, Seifalian AM. Nanosilver as a new generation of nanoproduct in biomedical applications. Trends Biotechnol 2010;28:580-588.
22. Travan A, Marsich E, Donati I, et al. Silver-polysaccharide nanocomposite antimicrobial coatings for methacrylic thermosets. Acta Biomater 2011;7:337-346.
23. Sintubin L, Verstraete W, Boon N. Biologically produced nanosilver: current state and future perspectives. Biotechnol Bioeng 2012;109:2422-2436.
24. Nanda A, Saravanan M. Biosynthesis of silver nanoparticles from Staphylococcus aureus and its antimicrobial activity against MRSA and MRSE. Nanomedicine 2009;5:452-456.
25. Bhainsa KC, D'Souza SF. Extracellular biosynthesis of silver nanoparticles using the fungus Aspergillus fumigatus. Colloids Surf B Biointerfaces 2006;47:160-164.
26. Chen W, Liu Y, Courtney HS, et al. In vitro anti-bacterial and biological properties of magnetron co-sputtered silver-containing hydroxyapatite coating. Biomaterials 2006;27:5512-5517.
27. Pala E, Trovarelli G, Calabrò T, et al. Survival of modern knee tumor megaprostheses: failures, functional results, and a comparative statistical analysis. Clin Orthop Relat Res 2015;473:891-899.
28. Angelini A, Drago G, Trovarelli G, Calabrò T, Ruggieri P. Infection after surgical resection for pelvic bone tumors: an analysis of 270 patients from one institution. Clin Orthop Relat Res 2014;472:349-359.
29. Angelini A, Henderson E, Trovarelli G, Ruggieri P. Is there a role for knee arthrodesis with modular endoprostheses for tumor and revision of failed endoprostheses? Clin Orthop Relat Res 2013;471:3326-3335.
30. Hardes J, Von Eiff C, Streitbuerger A, et al. Reduction of periprosthetic infection with silver-coated megaprostheses in patients with bone sarcoma. J Surg Oncol 2010;101:389-395.
31. Gosheger G, Hardes J, Ahrens H, et al. Silver-coated megaendoprostheses in a rabbit model-an analysis of the infection rate and toxicological side effects. Biomaterials 2004;25:5547-5556.
32. Mahan J, Seligson D, Henry SL, Hynes P, Dobbins J. Factors in pin tract infections. Orthopedics 1991;14:305-308.
33. Jennison T, McNally M, Pandit H. Prevention of infection in external fixator pin sites. Acta Biomater 2014;10:595-603.
34. Furkert FH, Sörensen JH, Arnoldi J, Robioneck B, Steckel H. Antimicrobial efficacy of surface-coated external fixation pins. Curr Microbiol 2011;62:1743-1751.
35. Wassall MA, Santin M, Isalberti C, Cannas M, Denyer SP. Adhesion of bacteria to stainless steel and silver-coated orthopedic external fixation pins. J Biomed Mater Res 1997;36:325-330.
36. Collinge CA, Goll G, Seligson D, Easley KJ. Pin tract infections: silver vs uncoated pins. Orthopedics 1994;17:445-448.
37. Coester LM, Nepola JV, Allen J, Marsh JL. The effects of silver coated external fixation pins. Iowa Orthop J 2006;26:48-53.
38. Massè A, Bruno A, Bosetti M, et al. Prevention of pin track infection in external fixation with silver coated pins: clinical and microbiological results. J Biomed Mater Res 2000;53:600-604.
39. Tamura K. Some effects of weak direct current and silver ions on experimental osteomyelitis and their clinical application. Nihon Seikeigeka Gakkai Zasshi 1983;57:187-197.
40. Webster DA, Spadaro JA, Becker RO, Kramer S. Silver anode treatment of chronic osteomyelitis. Clin Orthop Relat Res 1981;161:105-114.
41. Nand S, Sengar GK, Nand S, Jain VK, Gupta TD. Dual use of silver for management of chronic bone infections and infected non-unions. J Indian Med Assoc 1996;94:91-95.
42. Becker RO, Spadaro JA. Treatment of orthopaedic infections with electrically generated silver ions. A preliminary report. J Bone Joint Surg [Am] 1978;60-A:871-881.
43. Journeaux SF, Johnson N, Bryce SL, et al. Bacterial contamination rates during bone allograft retrieval. J Arthroplasty 1999;14:677-681.
44. Zheng Z, Yin W, Zara JN, et al. The use of BMP-2 coupled - Nanosilver-PLGA composite grafts to induce bone repair in grossly infected segmental defects. Biomaterials 2010;31:9293-9300.
45. Chen W, Liu Y, Courtney HS, et al. In vitro anti-bacterial and biological properties of magnetron co-sputtered silver-containing hydroxyapatite coating. Biomaterials 2006;27:5512-5517.
46. Journeaux SF, Johnson N, Bryce SL, et al. Bacterial contamination rates during bone allograft retrieval. J Arthroplasty 1999;14:677-681.
47. Suwanprateeb J, Thammarakcharoen F, Wasoontararat K, Chokevivat W, Phanphiriya P. Single step preparation of nanosilver loaded calcium phosphate by low temperature co-conversion process. J Mater Sci Mater Med 2012;23:2091-2100.
48. Sahni G, Gopinath P, Jeevanandam P. A novel thermal decomposition approach to synthesize hydroxyapatite-silver nanocomposites and their antibacterial action against GFP-expressing antibiotic resistant E. coli. Colloids Surf B Biointerfaces 2013;103:441-447.
49. Samani S, Hossainalipour SM, Tamizifar M, Rezaie HR. In vitro antibacterial evaluation of sol-gel-derived Zn-, Ag-, and (Zn + Ag)-doped hydroxyapatite coatings against methicillin-resistant Staphylococcus aureus. J Biomed Mater Res A 2013;101:222-230.
50. Sandukas S, Yamamoto A, Rabiei A. Osteoblast adhesion to functionally graded hydroxyapatite coatings doped with silver. J Biomed Mater Res A 2011;97:490-497.
51. Pulido L, Ghanem E, Joshi A, Purtill JJ, Parvizi J. Periprosthetic Joint Infection: the incidence, timing, and predisposing factors. Clin Orthop Relat Res 2008;466:1710-1715.
52. Ghani Y, Coathup MJ, Hing KA, Blunn GW. Development of a hydroxyapatite coating containing silver for the prevention of peri-prosthetic infection. J Orthop Res 2012;30:356-363.
53. Shimazaki T, Miyamoto H, Ando Y, et al. In vivo antibacterial and silver-releasing properties of novel thermal sprayed silver-containing hydroxyapatite coating. J Biomed Mater Res B Appl Biomater 2010;92:386-389.
54. Akiyama T, Miyamoto H, Yonekura Y, et al. Silver oxide-containing hydroxyapatite coating has in vivo antibacterial activity in the rat tibia. J Orthop Res 2013;31:1195-1200.
55. Alt V, Bechert T, Steinrücke P, et al. An in vitro assessment of the antibacterial properties and cytotoxicity of nanoparticulate silver bone cement. Biomaterials 2004;25:4383-4391.
56. Prokopovich P, Leech R, Carmalt CJ, Parkin IP, Perni S. A novel bone cement impregnated with silver-tiopronin nanoparticles: its antimicrobial, cytotoxic, and mechanical properties. Int J Nanomedicine 2013;8:2227-2237.
57. Wilkinson LJ, White RJ, Chipman JK. Silver and nanoparticles of silver in wound dressings: a review of efficacy and safety. J Wound Care 2011;20:543-549.
58. Ewald A, Glückermann SK, Thull R, Gbureck U. Antimicrobial titanium/silver PVD coatings on titanium. Biomed Eng Online 2006;5:22.
59. Das K, Bose S, Bandyopadhyay A, Karandikar B, Gibbins BL. Surface coatings for improvement of bone cell materials and antimicrobial activities of Ti implants. J Biomed Mater Res B Appl Biomater 2008;87:455-460.
60. Sheehan E, McKenna J, Mulhall KJ, Marks P, McCormack D. Adhesion of Staphylococcus to orthopaedic metals, an in vivo study. J Orthop Res 2004;22:39-43.
61. Kose N, Otuzbir A, Pekşen C, Kiremitçi A, Doʇan A. A silver ion-doped calcium phosphate-based ceramic nanopowder-coated prosthesis increased infection resistance. Clin Orthop Relat Res 2013;471:2532-2539.
62. Yuan X, Setyawati MI, Tan AS, et al. Highly luminescent silver nanoclusters with tunable emissions: cyclic reduction-decomposition synthesis and antimicrobial property. NPG Asia Mat 2013;5:39.
63. Prucek R, Tuèek J, Kilianová M, et al. The targeted antibacterial and antifungal properties of magnetic nanocomposite of iron oxide and silver nanoparticles. Biomaterials 2011;32:4704-4713.
64. Gray JE, Norton PR, Alnouno R, et al. Biological efficacy of electroless-deposited silver on plasma activated polyurethane. Biomaterials 2003;24:2759-2765.
65. Hasegawa M, Yoshida K, Wakabayashi H, Sudo A. Prevalence of adverse reactions to metal debris following metal-on-metal THA. Orthopedics 2013;36:606-612.
66. Sullivan MP, McHale KJ, Parvizi J, Mehta S. Nanotechnology: current concepts in orthopaedic surgery and future directions. Bone Joint J 2014;96-B:569-573.
67. Lee KJ, Nallathamby PD, Browning LM, Osgood CJ, Xu XH. In vivo imaging of transport and biocompatibility of single silver nanoparticles in early development of zebrafish embryos. ACS Nano 2007;1:133-143.
68. Cheng X, Zhang W, Ji Y, et al. Revealing silver cytotoxicity using Au nanorods/Ag shell nanostructures: disrupting cell membrane and causing apoptosis through oxidative damage. RSC Adv 2013;3:2296-2305.
69. Asha Rani PV, Low Kah Mun G, Hande MP, Valiyaveettil S. Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano 2009;3:279-290.
70. De Jong WH, Van Der Ven LT, Sleijffers A, et al. Systemic and immunotoxicity of silver nanoparticles in an intravenous 28 days repeated dose toxicity study in rats. Biomaterials 2013;34:8333-8343.
71. Wang Z, Sun Y, Wang D, Liu H, Boughton RI. In situ fabrication of silver nanoparticlefilled hydrogen titanate nanotube layer on metallic titanium surface for bacteriostatic and biocompatible implantation. Int J Nanomedicine 2013;8:2903-2916.
72. Pauksch L, Hartmann S, Rohnke M, et al. Biocompatibility of silver nanoparticles and silver ions in primary human mesenchymal stem cells and osteoblasts. Acta Biomater 2014;10:439-449.
73. Greulich C, Diendorf J, Simon T, et al. Uptake and intracellular distribution of silver nanoparticles in human mesenchymal stem cells. Acta Biomater 2011;7:347-354.
74. Necula BS, Van Leeuwen JP, Fratila-Apachitei LE, et al. In vitro cytotoxicity evaluation of porous TiO?-Ag antibacterial coatings for human fetal osteoblasts. Acta Biomater 2012;8:4191-4197.
75. Albers CE, Hofstetter W, Siebenrock KA, Landmann R, Klenke FM. In vitro cytotoxicity of silver nanoparticles on osteoblasts and osteoclasts at antibacterial concentrations. Nanotoxicology 2013;7:30-36.
76. Powers CM, Badireddy AR, Ryde IT, Seidler FJ, Slotkin TA. Silver nanoparticles compromise neurodevelopment in PC12 cells: critical contributions of silver ion, particle size, coating, and composition. Environ Health Perspect 2011;119:37-44.
77. Powers CM, Levin ED, Seidler FJ, Slotkin TA. Silver exposure in developing zebrafish produces persistent synaptic and behavioral changes. Neurotoxicol Teratol 2011;33:329-332.
78. Powers CM, Slotkin TA, Seidler FJ, Badireddy AR, Padilla S. Silver nanoparticles alter zebrafish development and larval behavior: distinct roles for particle size, coating and composition. Neurotoxicol Teratol 2011;33:708-714.
79. Kovvuru P, Mancilla PE, Shirode AB, et al. Oral ingestion of silver nanoparticles induces genomic instability and DNA damage in multiple tissues. Nanotoxicology 2014; (Epub ahead of print).
80. Ucciferri N, Collnot EM, Gaiser BK, et al. In vitro toxicological screening of nanoparticles on primary human endothelial cells and the role of flow in modulating cell response. Nanotoxicology 2014;8:697-708.
81. Martínez-Gutierrez F, Thi EP, Silverman JM, et al. Antibacterial activity, inflammatory response, coagulation and cytotoxicity effects of silver nanoparticles. Nanomedicine 2012;8:328-336.
82. Vik H, Andersen KJ, Julshamn K, Todnem K. Neuropathy caused by silver absorption from arthroplasty cement. Lancet 1985;1:872.
83. Sudmann E, Vik H, Rait M, et al. Systemic and local silver accumulation after total hip replacement using silver-impregnated bone cement. Med Prog Technol 1994;20:179-184.