Silver oxide-containing hydroxyapatite coating has in vivo antibacterial activity in the rat tibia

Journal of Orthopaedic Research

Volumn 31, Issue 8, 2013, Pages 1195-1200

  Akiyama, Takayuki ^a   Miyamoto, Hiroshi ^a   Yonekura, Yutaka ^a   Tsukamoto, Masatsugu ^a   Ando, Yoshiki ^a,b   Noda, Iwao ^a,b   Sonohata, Motoki ^a   Mawatari, Masaaki ^a  

^a SAGA UNIVERSITY   (Japan)

^b KYOCERA CORPORATION   (Japan)

Author keywords

antibacterial activity; hydroxyapatite; implant; methicillin resistant Staphylococcus aureus (MRSA); silver

Indexed keywords

HYDROXYAPATITE; METAL OXIDE; SILVER OXIDE; TITANIUM; UNCLASSIFIED DRUG;

ABSCESS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL COUNT; BACTERIAL STRAIN; BLOOD LEVEL; BONE IMPLANT; BONE INFECTION; COLONY FORMING UNIT; CONTROLLED STUDY; CORTICAL BONE; DISEASE SEVERITY; HISTOPATHOLOGY; IN VIVO STUDY; INFECTION PREVENTION; INOCULATION; MALE; MATERIAL COATING; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; OSTEOLYSIS; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; SCORING SYSTEM; SURGICAL INFECTION; TIBIA;

ABSCESS; ANIMALS; ANTI-INFECTIVE AGENTS; BONE NAILS; COATED MATERIALS, BIOCOMPATIBLE; DISEASE MODELS, ANIMAL; HYDROXYAPATITES; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON, SCANNING; OSTEOMYELITIS; OXIDES; RATS; RATS, SPRAGUE-DAWLEY; SILVER COMPOUNDS; STAPHYLOCOCCAL INFECTIONS; SURGICAL WOUND INFECTION; TIBIA; TITANIUM;

EID: 84879412966     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22357     Document Type: Article

References (24)

1. Cuckler JM., 2005. The infected total knee: management options. J Arthroplasty 20: 33-36.
2. Joulie D, Girard J, Mares O, et al. 2011. Factors governing the healing of Staphylococcus aureus infections following hip and knee prosthesis implantation: a retrospective study of 95 patients. Orthop Traumatol Surg Res 97: 685-692.
3. Zimmerli W, Trampuz A, Ochsner PE., 2004. Prosthetic-joint infections. N Engl J Med 351: 1645-1654.
4. Elek SD, Conen PE., 1957. The virulence of Staphylococcus pyogenes for man; a study of the problems of wound infection. Br J Exp Pathol 38: 573-586.
5. Casey AL, Karpanen TJ, Nightingale P, et al. 2012. Microbiological comparison of a silver-coated and a non-coated needleless intravascular connector in clinical use. J Hosp Infect 80: 299-303.
6. Davenport K, Keeley FX., 2005. Evidence for the use of silver-alloy-coated urethral catheters. J Hosp Infect 60: 298-303.
7. Hardes J, Ahrens H, Gebert C, et al. 2007. Lack of toxicological side-effects in silver-coated megaprostheses in humans. Biomaterials 28: 2869-2875.
8. Hardes J, von Eiff C, Streitbuerger A, et al. 2010. Reduction of periprosthetic infection with silver-coated megaprostheses in patients with bone sarcoma. J Surg Oncol 101: 389-395.
9. Noda I, Miyaji F, Ando Y, et al. 2009. Development of novel thermal sprayed antibacterial coating and evaluation of release properties of silver ions. J Biomed Mater Res B Appl Biomater 89B: 456-465.
10. Ando Y, Miyamoto H, Noda I, et al. 2010. Effect of bacterial media on the evaluation of the antibacterial activity of a biomaterial containing inorganic antibacterial reagents or antibiotics. Biocontrol Sci 15: 15-19.
11. Ando Y, Miyamoto H, Noda I, et al. 2010. Calcium phosphate coating containing silver shows high antibacterial activity and low cytotoxicity and inhibits bacterial adhesion. Mater Sci Eng C 30: 175-180. 20.
12. Shimazaki T, Miyamoto H, Ando Y, et al. 2010. In vivo antibacterial and silver-releasing properties of novel thermal sprayed silver-containing hydroxyapatite coating. J Biomed Mater Res B Appl Biomater 92: 386-389.
13. Yonekura Y, Miyamoto H, Shimazaki T, et al. 2011. Osteoconductivity of thermal-sprayed silver-containing hydroxyapatite coating in the rat tibia. J Bone Joint Surg Br 93: 644-649.
14. Lucke M, Schmidmaier G, Sadoni S, et al. 2003. A new model of implant-related osteomyelitis in rats. J Biomed Mater Res B Appl Biomater 67: 593-602.
15. Kaiser S, Jorulf H, Hirsch G., 1998. Clinical value of imaging techniques in childhood osteomyelitis. Acta Radiol 39: 523-531.
16. Nath S, Kalmodia S, Basu B., 2009. Densification, phase stability and in vitro biocompatibility property of hydroxyapatite-10 wt% silver composites. J Mater Sci Mater Med 21: 1273-1287.
17. Rameshbabu N, Sampath Kumar TS, Prabhakar TG, et al. 2007. Antibacterial nanosized silver substituted hydroxyapatite: synthesis and characterization. J Biomed Mater Res A 80: 581-591.
18. Stanic̈ V, Janac̈kovic̈ D, Dimitrijevic̈ S, et al. 2011. Synthesis of antimicrobial monophase silver-doped hydroxyapatite nanopowders for bone tissue engineering. Appl Surf Sci 257: 4510-4518.
19. Bragg PD, Rainnie DJ., 1974. The effect of silver ions on the respiratory chain of Escherichia coli. Can J Microbiol 20: 883-889.
20. Darouiche RO., 1999. Anti-infective efficacy of silver-coated medical prostheses. Clin Infect Dis 29: 1371-1377; quiz 1378.
21. Schreurs WJ, Rosenberg H., 1982. Effect of silver ions on transport and retention of phosphate by Escherichia coli. J Bacteriol 152: 7-13.
22. Bai X, Sandukas S, Appleford M, et al. 2012. Antibacterial effect and cytotoxicity of Ag-doped functionally graded hydroxyapatite coatings. J Biom Mater Res B Appl Biomater 100B: 553-561.
23. de Lima R, Seabra AB, Duran N., 2012. Silver nanoparticles: a brief review of cytotoxicity and genotoxicity of chemically and biogenically synthesized nanoparticles. J Appl Toxicol 32: 867-879.
24. You C, Han C, Wang X, et al. 2012. The progress of silver nanoparticles in the antibacterial mechanism, clinical application and cytotoxicity. Mol Biol Rep 39: 9193-9201.