Neurologic injury in neonates with congenital heart disease during extracorporeal membrane oxygenation: An analysis of extracorporeal life support organization registry data

ASAIO Journal

Volumn 61, Issue 1, 2015, Pages 43-48

  Polito, Angelo ^a   Barrett, Cindy S ^b   Rycus, Peter T ^c   Favia, Isabella ^a   Cogo, Paola E ^a   Thiagarajan, Ravi R ^d  

^a BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^b CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

brain injuries; congenital heart disease; extracorporeal membrane oxygenation; newborn

Indexed keywords

CARDIOLOGY; CARDIOVASCULAR SURGERY; DISEASES; RESPIRATORY THERAPY; RESUSCITATION;

BIRTH WEIGHT; CARDIAC SURGERY; CARDIOPULMONARY RESUSCITATION; COHORT STUDIES; CONFIDENCE INTERVAL; CONGENITAL HEART DISEASE; EXTRACORPOREAL MEMBRANE OXYGENATION; HOSPITAL MORTALITY;

HEART;

ARTIFICIAL LUNG SURFACTANT; NITRIC OXIDE;

ARTERIAL TRUNK; ARTICLE; BLOOD PH; BRAIN HEMORRHAGE; BRAIN INJURY; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; COHORT ANALYSIS; CONGENITAL HEART DISEASE; CONTROLLED STUDY; DISEASE SEVERITY; EXTRACORPOREAL MEMBRANE OXYGENATION DEVICE; EXTRACORPOREAL OXYGENATION; FALLOT TETRALOGY; FEMALE; GREAT VESSELS TRANSPOSITION; HEART SINGLE VENTRICLE; HEART SURGERY; HIGH FREQUENCY VENTILATION; HUMAN; HYPOPLASTIC LEFT HEART SYNDROME; INCIDENCE; LUNG VEIN DRAINAGE ANOMALY; MALE; MEAN ARTERIAL PRESSURE; MORTALITY; NEUROMONITORING; NEWBORN; NEWBORN DISEASE; NEWBORN MORTALITY; OXYGEN SATURATION; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; PULMONARY VALVE STENOSIS; REGISTER; RESUSCITATION; RETROSPECTIVE STUDY; SYSTOLIC BLOOD PRESSURE; ADVERSE EFFECTS; BRAIN INJURIES; COMPLICATION; HEART DEFECTS, CONGENITAL; MULTIVARIATE ANALYSIS; RISK FACTOR; STATISTICAL MODEL;

BRAIN INJURIES; COHORT STUDIES; EXTRACORPOREAL MEMBRANE OXYGENATION; FEMALE; HEART DEFECTS, CONGENITAL; HUMANS; INFANT, NEWBORN; LOGISTIC MODELS; MALE; MULTIVARIATE ANALYSIS; REGISTRIES; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84929043544     PISSN: 10582916     EISSN: 1538943X     Source Type: Journal    
DOI: 10.1097/MAT.0000000000000151     Document Type: Article

References (30)

1. Wernovsky G. Improving neurologic and quality-of-life outcomes in children with congenital heart disease: Past, present, and future. J Thorac Cardiovasc Surg 135: 240-242, 2008
2. Thiagarajan RR, Laussen PC, Rycus PT, Bartlett RH, Bratton SL. Extracorporeal membrane oxygenation to aid cardiopulmonary resuscitation in infants and children. Circulation 116: 1693-1700, 2007
3. Barrett CS, Bratton SL, Salvin JW, Laussen PC, Rycus PT, Thiagarajan RR. Neurological injury after extracorporeal membrane oxygenation use to aid pediatric cardiopulmonary resuscitation. Pediatr Crit Care Med 10: 445-451, 2009
4. Lequier L, Joffe AR, Robertson CM, et al. Western Canadian Complex Pediatric Therapies Program Follow-up Group: Twoyear survival, mental, and motor outcomes after cardiac extracorporeal life support at less than five years of age. J Thorac Cardiovasc Surg 136: 976-983, 2008
5. Costello JM, O'Brien M, Wypij D, et al. Quality of life of pediatric cardiac patients who previously required extracorporeal membrane oxygenation. Pediatr Crit Care Med 13: 428-434, 2012
6. Cengiz P, Seidel K, Rycus PT, Brogan TV, Roberts JS. Central nervous system complications during pediatric extracorporeal life support: Incidence and risk factors. Crit Care Med 33: 2817-2824, 2005
7. Hardart GE, Fackler JC. Predictors of intracranial hemorrhage during neonatal extracorporeal membrane oxygenation. J Pediatr 134: 156-159, 1999
8. Polito A, Barrett CS, Wypij D, et al. Neurologic complications in neonates supported with extracorporeal membrane oxygenation. An analysis of ELSO registry data. Intensive Care Med 39: 1594-1601, 2013
9. Bhat P, Hirsch JC, Gelehrter S, et al. Outcomes of infants weighing three kilograms or less requiring extracorporeal membrane oxygenation after cardiac surgery. Ann Thorac Surg 95: 656-661, 2013
10. Lasa JJ, Cohen MS, Wernovsky G, Pinto NM. Is race associated with morbidity and mortality after hospital discharge among neonates undergoing heart surgery?. Pediatr Cardiol 34: 415-423, 2013
11. Ferriero DM. Neonatal brain injury. N Engl J Med 351: 1985-1995, 2004
12. Marino BS, Lipkin PH, Newburger JW, et al. American Heart Association Congenital Heart Defects Committee, Council on Cardiovascular Disease in the Young, Council on Cardiovascular Nursing, and Stroke Council: Neurodevelopmental outcomes in children with congenital heart disease: Evaluation and management: A scientific statement from the American Heart Association. Circulation 126: 1143-1172, 2012
13. Kaltman JR, Di H, Tian Z, Rychik J. Impact of congenital heart disease on cerebrovascular blood flow dynamics in the fetus. Ultrasound Obstet Gynecol 25: 32-36, 2005
14. Licht DJ, Wang J, Silvestre DW, et al. Preoperative cerebral blood flow is diminished in neonates with severe congenital heart defects. J Thorac Cardiovasc Surg 128: 841-849, 2004
15. Licht DJ, Shera DM, Clancy RR, et al. Brain maturation is delayed in infants with complex congenital heart defects. J Thorac Cardiovasc Surg 137: 529-536; discussion 536, 2009
16. Limperopoulos C, Tworetzky W, McElhinney DB, et al. Brain volume and metabolism in fetuses with congenital heart disease: Evaluation with quantitative magnetic resonance imaging and spectroscopy. Circulation 121: 26-33, 2010
17. Kurth CD, Steven JM, Nicolson SC, Jacobs ML. Cerebral oxygenation during cardiopulmonary bypass in children. J Thorac Cardiovasc Surg 113: 71-78; discussion 78, 1997
18. Newburger JW, Jonas RA, Wernovsky G, et al. A comparison of the perioperative neurologic effects of hypothermic circulatory arrest versus low-flow cardiopulmonary bypass in infant heart surgery. N Engl J Med 329: 1057-1064, 1993
19. Jonas RA, Wypij D, Roth SJ, et al. The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass: Results of a randomized trial in infants. J Thorac Cardiovasc Surg 126: 1765-1774, 2003
20. Hirsch JC, Jacobs ML, Andropoulos D, et al. Protecting the infant brain during cardiac surgery: A systematic review. Ann Thorac Surg 94: 1365-1373; discussion 1373, 2012
21. Beca J, Gunn JK, Coleman L, et al. New white matter brain injury after infant heart surgery is associated with diagnostic group and the use of circulatory arrest. Circulation 127: 971-979, 2013
22. Miller SP, McQuillen PS, Hamrick S, et al. Abnormal brain development in newborns with congenital heart disease. N Engl J Med 357: 1928-1938, 2007
23. Galli KK, Zimmerman RA, Jarvik GP, et al. Periventricular leukomalacia is common after neonatal cardiac surgery. J Thorac Cardiovasc Surg 127: 692-704, 2004
24. Dent CL, Spaeth JP, Jones BV, et al. Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion. J Thorac Cardiovasc Surg 131: 190-197, 2006
25. Dimitropoulos A, McQuillen PS, Sethi V, et al. Brain injury and development in newborns with critical congenital heart disease. Neurology 81: 241-248, 2013
26. Revenis ME, Glass P, Short BL. Mortality and morbidity rates among lower birth weight infants (2000 to 2500 grams) treated with extracorporeal membrane oxygenation. J Pediatr 121: 452-458, 1992
27. Sarkar S, Bhagat I, Dechert R, Schumacher RE, Donn SM. Severe intraventricular hemorrhage in preterm infants: Comparison of risk factors and short-term neonatal morbidities between grade 3 and grade 4 intraventricular hemorrhage. Am J Perinatol 26: 419-424, 2009
28. Rozmiarek AJ, Qureshi FG, Cassidy L, et al. How low can you go?. Effectiveness and safety of extracorporeal membrane oxygenation in low-birth-weight neonates. J Pediatr Surg 39: 845-847, 2004
29. Stewart A, Tekes A, Huisman TA, et al. Glial fibrillary acidic protein as a biomarker for periventricular white matter injury. Am J Obstet Gynecol 209: 27, 2013
30. Gaynor JW, Jarvik GP, Gerdes M, et al. Postoperative electroencephalographic seizures are associated with deficits in executive function and social behaviors at 4 years of age following cardiac surgery in infancy. J Thorac Cardiovasc Surg 146: 132-137, 2013