Neurologic complications in neonates supported with extracorporeal membrane oxygenation. An analysis of ELSO registry data

Intensive Care Medicine

Volumn 39, Issue 9, 2013, Pages 1594-1601

  Polito, Angelo ^a   Barrett, Cindy S ^b   Wypij, David ^c,e   Rycus, Peter T ^d   Netto, Roberta ^a   Cogo, Paola E ^a   Thiagarajan, Ravi R ^e  

^a BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^b CHILDREN S HOSPITAL   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

^e BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Brain injury; Extracorporeal membrane oxygenation; Neonate; Neurologic complications

Indexed keywords

BICARBONATE; SURFACTANT;

ARTERIAL GAS; ARTERIAL PH; ARTICLE; ARTIFICIAL VENTILATION; BIRTH WEIGHT; BLOOD GAS ANALYSIS; BLOOD PH; BRAIN DEATH; BRAIN HEMORRHAGE; BRAIN INFARCTION; CANNULATION; COHORT ANALYSIS; CONGENITAL HEART DISEASE; DIAPHRAGM HERNIA; DISEASE ASSOCIATION; DISEASE REGISTRY; EXTRACORPOREAL OXYGENATION; FEMALE; FOLLOW UP; GESTATIONAL AGE; HEART ARREST; HEART RIGHT ATRIUM; HUMAN; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MECONIUM ASPIRATION; MORTALITY; NEONATAL RESPIRATORY DISTRESS SYNDROME; NEUROLOGIC DISEASE; NEWBORN; NEWBORN CARE; NEWBORN SEPSIS; OXYGEN SATURATION; PATIENT SELECTION; PRESSURE; QUALITY OF LIFE; RESPIRATORY FAILURE; RESPIRATORY TRACT INFECTION; RESUSCITATION; RETROSPECTIVE STUDY; SEIZURE; TREATMENT INDICATION; VULNERABLE POPULATION;

COHORT STUDIES; EXTRACORPOREAL MEMBRANE OXYGENATION; FEMALE; HUMANS; INCIDENCE; INFANT, NEWBORN; MALE; NERVOUS SYSTEM DISEASES; ODDS RATIO; REGISTRIES; RETROSPECTIVE STUDIES;

EID: 84881470178     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-013-2985-x     Document Type: Article

References (33)

1. Cengiz P, Seidel K, Rycus PT, Brogan TV, Roberts JS (2005) Central nervous system complications during pediatric extracorporeal life support: incidence and risk factors. Crit Care Med 33:2817-2824
2. Barrett CS, Bratton SL, Salvin JW, Laussen PC, Rycus PT, Thiagarajan RR (2009) Neurological injury after extracorporeal membrane oxygenation use to aid pediatric cardiopulmonary resuscitation. Pediatr Crit Care Med 10:445-451
3. Bulas D, Glass P (2005) Neonatal ECMO: neuroimaging and neurodevelopmental outcome. Semin Perinatol 29:58-65
4. Short BL (2005) The effect of extracorporeal life support on the brain: a focus on ECMO. Semin Perinatol 29:45-50
5. Volpe JJ (2008) Intracranial Hemorrhage: Subdural, Primary Subarachanoid, Cerebral, Intraventricular (Term Infant) and Miscellaneous. In: Volpe JJ (ed) Neurology of the newborn. Saunders Elsevier, Philadelphia, pp 483-516
6. Hervey-Jumper SL, Annich GM, Yancon AR, Garton HJ, Muraszko KM, Maher CO (2011) Neurological complications of extracorporeal membrane oxygenation in children. J Neurosurg Pediatr 7:338-344
7. Thiagarajan RR, Laussen PC, Rycus PT, Bartlett RH, Bratton SL (2007) Extracorporeal membrane oxygenation to aid cardiopulmonary resuscitation in infants and children. Circulation 116:1693-1700
8. Sivarajan VB, Best D, Brizard CP, Shekerdemian LS, d'Udekem Y, Butt W (2011) Duration of resuscitation prior to rescue extracorporeal membrane oxygenation impacts outcome in children with heart disease. Intensive Care Med 37:853-860
9. Hardart GE, Fackler JC (1999) Predictors of intracranial hemorrhage during neonatal extracorporeal membrane oxygenation. J Pediatr 134:156-159
10. Hardart GE, Hardart MK, Arnold JH (2004) Intracranial hemorrhage in premature neonates treated with extracorporeal membrane oxygenation correlates with conceptional age. J Pediatr 145:184-189
11. Conrad SA, Rycus P (2012) The registry of the extracorporeal life support organization. In: Annich GM, Lynch WR, MacLaren G, Wilson JM, Bartlett RH (eds) ECMO: extracorporeal cardiopulmonary support in critical care. Extracorporeal Life Support Organization, Ann Arbor, pp 87-104
12. Graziani LJ, Gringlas M, Baumgart S (1997) Cerebrovascular complications and neurodevelopmental sequelae of neonatal ECMO. Clin Perinatol 24:655-675
13. Short BL, Bender K, Walker LK, Traystman RJ (1994) The cerebrovascular response to prolonged hypoxia with carotid artery and jugular vein ligation in the newborn lamb. J Pediatr Surg 29:887-891
14. Short BL, Walker LK, Traystman RJ (1994) Impaired cerebral autoregulation in the newborn lamb during recovery from severe, prolonged hypoxia, combined with carotid artery and jugular vein ligation. Crit Care Med 22:1262-1268
15. Tweed A, Cote J, Lou H, Gregory G, Wade J (1986) Impairment of cerebral blood flow autoregulation in the newborn lamb by hypoxia. Pediatr Res 20:516-519
16. Biehl DA, Stewart DL, Forti NH, Cook LN (1996) Timing of intracranial hemorrhage during extracorporeal life support. ASAIO J 42:938-941
17. Dela Cruz TV, Stewart DL, Winston SJ, Weatherman KS, Phelps JL, Mendoza JC (1997) Risk factors for intracranial hemorrhage in the extracorporeal membrane oxygenation patient. J Perinatol 17:18-23
18. Grayck EN, Meliones JN, Kern FH, Hansell DR, Ungerleider RM, Greeley WJ (1995) Elevated serum lactate correlates with intracranial hemorrhage in neonates treated with extracorporeal life support. Pediatrics 96:914-917
19. Khan AM, Shabarek FM, Zwischenberger JB, Warner BW, Cheu HW, Jaksic T, Goretsky MJ, Meyer TA, Doski J, Lally KP (1998) Utility of daily head ultrasonography for infants on extracorporeal membrane oxygenation. J Pediatr Surg 33:1229-1232
20. Meyer DM, Jessen ME (1995) Results of extracorporeal membrane oxygenation in neonates with sepsis. The extracorporeal life support organization experience. J Thorac Cardiovasc Surg 109:419-425 Discussion 425-427
21. Wilson JM, Bower LK, Fackler JC, Beals DA, Bergus BO, Kevy SV (1993) Aminocaproic acid decreases the incidence of intracranial hemorrhage and other hemorrhagic complications of ECMO. J Pediatr Surg 28:536-540 Discussion 540-531
22. Downard CD, Betit P, Chang RW, Garza JJ, Arnold JH, Wilson JM (2003) Impact of AMICAR on hemorrhagic complications of ECMO: a ten-year review. J Pediatr Surg 38:1212-1216
23. Rollins MD, Hubbard A, Zabrocki L, Barnhart DC, Bratton SL (2012) Extracorporeal membrane oxygenation cannulation trends for pediatric respiratory failure and central nervous system injury. J Pediatr Surg 47:68-75
24. Perlman JM, Altman DI (1992) Symmetric cerebral blood flow in newborns who have undergone successful extracorporeal membrane oxygenation. Pediatrics 89:235-239
25. Lohrer RM, Bejar RF, Simko AJ, Moulton SL, Cornish JD (1992) Internal carotid artery blood flow velocities before, during, and after extracorporeal membrane oxygenation. Am J Dis Child 146:201-207
26. Rozmiarek AJ, Qureshi FG, Cassidy L, Ford HR, Gaines BA, Rycus P, Hackam DJ (2004) How low can you go? Effectiveness and safety of extracorporeal membrane oxygenation in low-birth-weight neonates. J Pediatr Surg 39:845-847
27. Back SA, Riddle A, McClure MM (2007) Maturation-dependent vulnerability of perinatal white matter in premature birth. Stroke 38:724-730
28. Volpe JJ (2008) Intracranial Hemorrhage: germinal matrix - intraventricular hemorrhage of the premature infant. In: Volpe JJ (ed) Neurology of the newborn. Saunders Elsevier, Philadelphia, pp 517-588
29. Meehan JJ, Haney BM, Snyder CL, Sharp RJ, Acosta JM, Holcomb GW 3rd (2002) Outcome after recannulation and a second course of extracorporeal membrane oxygenation. J Pediatr Surg 37:845-850
30. Shankaran S, Laptook AR, Ehrenkranz RA, Tyson JE, McDonald SA, Donovan EF, Fanaroff AA, Poole WK, Wright LL, Higgins RD, Finer NN, Carlo WA, Duara S, Oh W, Cotten CM, Stevenson DK, Stoll BJ, Lemons JA, Guillet R, Jobe AH (2005) Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med 353:1574-1584
31. Azzopardi DV, Strohm B, Edwards AD, Dyet L, Halliday HL, Juszczak E, Kapellou O, Levene M, Marlow N, Porter E, Thoresen M, Whitelaw A, Brocklehurst P (2009) Moderate hypothermia to treat perinatal asphyxial encephalopathy. N Engl J Med 361:1349-1358
32. Murray DM, Boylan GB, Ali I, Ryan CA, Murphy BP, Connolly S (2008) Defining the gap between electrographic seizure burden, clinical expression and staff recognition of neonatal seizures. Arch Dis Child Fetal Neonatal Ed 93:F187-F191
33. Clancy RR, McGaurn SA, Wernovsky G, Gaynor JW, Spray TL, Norwood WI, Jacobs ML, Goin JE (2003) Risk of seizures in survivors of newborn heart surgery using deep hypothermic circulatory arrest. Pediatrics 111:592-601