-
1
-
-
0035924320
-
Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
-
A. Ohta, M. Sitkovsky, Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature 414, 916-920 (2001).
-
(2001)
Nature
, vol.414
, pp. 916-920
-
-
Ohta, A.1
Sitkovsky, M.2
-
2
-
-
33748357735
-
A2A adenosine receptor protects tumors from antitumor T cells
-
A. Ohta, E. Gorelik, S. J. Prasad, F. Ronchese, D. Lukashev, M. K. K. Wong, X. Huang, S. Caldwell, K. Liu, P. Smith, J.-F. Chen, E. K. Jackson, S. Apasov, S. Abrams, M. Sitkovsky, A2A adenosine receptor protects tumors from antitumor T cells. Proc. Natl. Acad. Sci. U.S.A. 103, 13132-13137 (2006).
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 13132-13137
-
-
Ohta, A.1
Gorelik, E.2
Prasad, S.J.3
Ronchese, F.4
Lukashev, D.5
Wong, M.K.K.6
Huang, X.7
Caldwell, S.8
Liu, K.9
Smith, P.10
Chen, J.-F.11
Jackson, E.K.12
Apasov, S.13
Abrams, S.14
Sitkovsky, M.15
-
5
-
-
61349158530
-
T regulatory cells: Hypoxia-adenosinergic suppression and re-direction of the immune response
-
M. V. Sitkovsky, T regulatory cells: Hypoxia-adenosinergic suppression and re-direction of the immune response. Trends Immunol. 30, 102-108 (2009).
-
(2009)
Trends Immunol.
, vol.30
, pp. 102-108
-
-
Sitkovsky, M.V.1
-
6
-
-
84964315622
-
Hostile, hypoxia-A2-adenosinergic tumor biology as the next barrier to overcome for tumor immunologists
-
M. V. Sitkovsky, S. Hatfield, R. Abbott, B. Belikoff, D. Lukashev, A. Ohta, Hostile, hypoxia-A2-adenosinergic tumor biology as the next barrier to overcome for tumor immunologists. Cancer Immunol. Res. 2, 598-605 (2014).
-
(2014)
Cancer Immunol. Res.
, vol.2
, pp. 598-605
-
-
Sitkovsky, M.V.1
Hatfield, S.2
Abbott, R.3
Belikoff, B.4
Lukashev, D.5
Ohta, A.6
-
7
-
-
41149097574
-
Adoptive cell transfer: A clinical path to effective cancer immunotherapy
-
S. A. Rosenberg, N. P. Restifo, J. C. Yang, R. A. Morgan, M. E. Dudley, Adoptive cell transfer: A clinical path to effective cancer immunotherapy. Nat. Rev. Cancer 8, 299-308 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 299-308
-
-
Rosenberg, S.A.1
Restifo, N.P.2
Yang, J.C.3
Morgan, R.A.4
Dudley, M.E.5
-
8
-
-
80054875641
-
Novel cancer immunotherapy agents with survival benefit: Recent successes and next steps
-
P. Sharma, K. Wagner, J. D. Wolchok, J. P. Allison, Novel cancer immunotherapy agents with survival benefit: Recent successes and next steps. Nat. Rev. Cancer 11, 805-812 (2011).
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 805-812
-
-
Sharma, P.1
Wagner, K.2
Wolchok, J.D.3
Allison, J.P.4
-
9
-
-
84927574518
-
Immune modulation for cancer therapy
-
J. Naidoo, D. B. Page, J. D. Wolchok, Immune modulation for cancer therapy. Br. J. Cancer 111, 2214-2219 (2014).
-
(2014)
Br. J. Cancer
, vol.111
, pp. 2214-2219
-
-
Naidoo, J.1
Page, D.B.2
Wolchok, J.D.3
-
10
-
-
84255197842
-
Cancer immunotherapy comes of age
-
I. Mellman, G. Coukos, G. Dranoff, Cancer immunotherapy comes of age. Nature 480, 480-489 (2011).
-
(2011)
Nature
, vol.480
, pp. 480-489
-
-
Mellman, I.1
Coukos, G.2
Dranoff, G.3
-
11
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
F. S. Hodi, S. J. O'Day, D. F. McDermott, R. W. Weber, J. A. Sosman, J. B. Haanen, R. Gonzalez, C. Robert, D. Schadendorf, J. C. Hassel, W. Akerley, A. J. van den Eertwegh, J. Lutzky, P. Lorigan, J. M. Vaubel, G. P. Linette, D. Hogg, C. H. Ottensmeier, C. Lebbé, C. Peschel, I. Quirt, J. I. Clark, J. D. Wolchok, J. S. Weber, J. Tian, M. J. Yellin, G. M. Nichol, A. Hoos, W. J. Urba, Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 363, 711-723 (2010).
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
Akerley, W.11
Eertwegh Den Van, A.J.12
Lutzky, J.13
Lorigan, P.14
Vaubel, J.M.15
Linette, G.P.16
Hogg, D.17
Ottensmeier, C.H.18
Lebbé, C.19
Peschel, C.20
Quirt, I.21
Clark, J.I.22
Wolchok, J.D.23
Weber, J.S.24
Tian, J.25
Yellin, M.J.26
Nichol, G.M.27
Hoos, A.28
Urba, W.J.29
more..
-
12
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
D. M. Pardoll, The blockade of immune checkpoints in cancer immunotherapy. Nat. Rev. Cancer 12, 252-264 (2012).
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
13
-
-
84905455228
-
Targeting cancer-derived adenosine: New therapeutic approaches
-
A. Young, D. Mittal, J. Stagg, M. J. Smyth, Targeting cancer-derived adenosine: New therapeutic approaches. Cancer Discov. 4, 879-888 (2014).
-
(2014)
Cancer Discov.
, vol.4
, pp. 879-888
-
-
Young, A.1
Mittal, D.2
Stagg, J.3
Smyth, M.J.4
-
14
-
-
36849010167
-
Adaptive immunity maintains occult cancer in an equilibrium state
-
C. M. Koebel, W. Vermi, J. B. Swann, N. Zerafa, S. J. Rodig, L. J. Old, M. J. Smyth, R. D. Schreiber, Adaptive immunity maintains occult cancer in an equilibrium state. Nature 450, 903-907 (2007).
-
(2007)
Nature
, vol.450
, pp. 903-907
-
-
Koebel, C.M.1
Vermi, W.2
Swann, J.B.3
Zerafa, N.4
Rodig, S.J.5
Old, L.J.6
Smyth, M.J.7
Schreiber, R.D.8
-
16
-
-
79961011452
-
Impact of CD39 and purinergic signalling on the growth and metastasis of colorectal cancer
-
B. M. Künzli, M. I. Bernlochner, S. Rath, S. Käser, E. Csizmadia, K. Enjyoji, P. Cowan, A. d'Apice, K. Dwyer, R. Rosenberg, A. Perren, H. Friess, C. A. Maurer, S. C. Robson, Impact of CD39 and purinergic signalling on the growth and metastasis of colorectal cancer. Purinergic Signal. 7, 231-241 (2011).
-
(2011)
Purinergic Signal.
, vol.7
, pp. 231-241
-
-
Künzli, B.M.1
Bernlochner, M.I.2
Rath, S.3
Käser, S.4
Csizmadia, E.5
Enjyoji, K.6
Cowan, P.7
D'Apice, A.8
Dwyer, K.9
Rosenberg, R.10
Perren, A.11
Friess, H.12
Maurer, C.A.13
Robson, S.C.14
-
17
-
-
75949112218
-
Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
-
J. Stagg, U. Divisekera, N. McLaughlin, J. Sharkey, S. Pommey, D. Denoyer, K. M. Dwyer, and M. J. Smyth, Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis. Proc. Natl. Acad. Sci. U.S.A. 107, 1547-1552 (2010).
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 1547-1552
-
-
Stagg, J.1
Divisekera, U.2
McLaughlin, N.3
Sharkey, J.4
Pommey, S.5
Denoyer, D.6
Dwyer, K.M.7
Smyth, M.J.8
-
18
-
-
79954576658
-
CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis
-
J. Stagg, U. Divisekera, H. Duret, T. Sparwasser, M. W. L. Teng, P. K. Darcy, M. J. Smyth, CD73-deficient mice have increased antitumor immunity and are resistant to experimental metastasis. Cancer Res. 71, 2892-2900 (2011).
-
(2011)
Cancer Res.
, vol.71
, pp. 2892-2900
-
-
Stagg, J.1
Divisekera, U.2
Duret, H.3
Sparwasser, T.4
Teng, M.W.L.5
Darcy, P.K.6
Smyth, M.J.7
-
19
-
-
77950231071
-
CD73 on tumor cells impairs antitumor T-cell responses: A novel mechanism of tumor-induced immune suppression
-
D. Jin, J. Fan, L. Wang, L. F. Thompson, A. Liu, B. J. Daniel, T. Shin, T. J. Curiel, B. Zhang, CD73 on tumor cells impairs antitumor T-cell responses: A novel mechanism of tumor-induced immune suppression. Cancer Res. 70, 2245-2255 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 2245-2255
-
-
Jin, D.1
Fan, J.2
Wang, L.3
Thompson, L.F.4
Liu, A.5
Daniel, B.J.6
Shin, T.7
Curiel, T.J.8
Zhang, B.9
-
20
-
-
84883422236
-
+ tumors
-
+ tumors. Proc. Natl. Acad. Sci. U.S.A. 110, 14711-14716 (2013).
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 14711-14716
-
-
Beavis, P.A.1
Divisekera, U.2
Paget, C.3
Chow, M.T.4
John, L.B.5
Devaud, C.6
Dwyer, K.7
Stagge, J.8
Smyth, M.J.9
Darcy, P.K.10
-
21
-
-
84879705407
-
CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer
-
S. Loi, S. Pommey, B. Haibe-Kains, P. A. Beavis, P. K. Darcy, M. J. Smyth, J. Stagg, CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer. Proc. Natl. Acad. Sci. U.S.A. 110, 11091-11096 (2013).
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 11091-11096
-
-
Loi, S.1
Pommey, S.2
Haibe-Kains, B.3
Beavis, P.A.4
Darcy, P.K.5
Smyth, M.J.6
Stagg, J.7
-
22
-
-
84873661506
-
Hyperoxic acute lung injury
-
R. H. Kallet, M. A. Matthay, Hyperoxic acute lung injury. Respir. Care 58, 123-141 (2013).
-
(2013)
Respir. Care
, vol.58
, pp. 123-141
-
-
Kallet, R.H.1
Matthay, M.A.2
-
23
-
-
22744450934
-
Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury
-
M. Thiel, A. Chouker, A. Ohta, E. Jackson, C Caldwell, P. Smith, D. Lukashev, I. Bittmann, M. V. Sitkovsky, Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury. PLOS Biol. 3, e174 (2005).
-
(2005)
PLOS Biol.
, vol.3
, pp. e174
-
-
Thiel, M.1
Chouker, A.2
Ohta, A.3
Jackson, E.4
Caldwell, C.5
Smith, P.6
Lukashev, D.7
Bittmann, I.8
Sitkovsky, M.V.9
-
24
-
-
84934436655
-
Tumor oxygenation: An appraisal of past and present concepts and a look into the future: Arisztid G. B. Kovách Lecture
-
P. Vaupel, Tumor oxygenation: An appraisal of past and present concepts and a look into the future: Arisztid G. B. Kovách Lecture. Adv. Exp. Med. Biol. 789, 229-236 (2013).
-
(2013)
Adv. Exp. Med. Biol.
, vol.789
, pp. 229-236
-
-
Vaupel, P.1
-
25
-
-
84914113076
-
Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1a-dependent and extracellular adenosine-mediated tumor protection
-
S. M. Hatfield, J. Kjaergaard, D. Lukashev, B. Belikoff, T. H. Schreiber, S. Sethumadhavan, R. Abbott, P. Philbrook, M. Thayer, D. Shujia, S. Rodig, J. L. Kutok, J. Ren, A. Ohta, E. R. Podack, B. Karger, E. K. Jackson, M. Sitkovsky, Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1a-dependent and extracellular adenosine-mediated tumor protection. J. Mol. Med. 92, 1283-1292 (2014).
-
(2014)
J. Mol. Med.
, vol.92
, pp. 1283-1292
-
-
Hatfield, S.M.1
Kjaergaard, J.2
Lukashev, D.3
Belikoff, B.4
Schreiber, T.H.5
Sethumadhavan, S.6
Abbott, R.7
Philbrook, P.8
Thayer, M.9
Shujia, D.10
Rodig, S.11
Kutok, J.L.12
Ren, J.13
Ohta, A.14
Podack, E.R.15
Karger, B.16
Jackson, E.K.17
Sitkovsky, M.18
-
26
-
-
44349157832
-
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
-
M. W. Dewhirst, Y. Cao, B. Moeller, Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response. Nat. Rev. Cancer 8, 425-437 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 425-437
-
-
Dewhirst, M.W.1
Cao, Y.2
Moeller, B.3
-
27
-
-
58149105356
-
Cancer cell killing via ROS: To increase or decrease, that is the question
-
J. Wang, J. Yi, Cancer cell killing via ROS: To increase or decrease, that is the question. Cancer Biol. Ther. 7, 1875-1884 (2008).
-
(2008)
Cancer Biol. Ther.
, vol.7
, pp. 1875-1884
-
-
Wang, J.1
Yi, J.2
-
28
-
-
84866461088
-
Synergistic protection against hyperoxia-induced lung injury by neutrophils blockade and EC-SOD overexpression
-
J. H. Min, C. N. Codipilly, S. Nasim, E. J. Miller, M. N. Ahmed, Synergistic protection against hyperoxia-induced lung injury by neutrophils blockade and EC-SOD overexpression. Respir. Res. 13, 58 (2012).
-
(2012)
Respir. Res.
, vol.13
, pp. 58
-
-
Min, J.H.1
Codipilly, C.N.2
Nasim, S.3
Miller, E.J.4
Ahmed, M.N.5
-
29
-
-
84868331578
-
Oxidative stress contributes to lung injury and barrier dysfunction via microtubule destabilization
-
E. Kratzer, Y. Tian, N. Sarich, T. Wu, A. Meliton, A. Leff, A. A. Birukova, Oxidative stress contributes to lung injury and barrier dysfunction via microtubule destabilization. Am. J. Respir. Cell Mol. Biol. 47, 688-697 (2012).
-
(2012)
Am. J. Respir. Cell Mol. Biol.
, vol.47
, pp. 688-697
-
-
Kratzer, E.1
Tian, Y.2
Sarich, N.3
Wu, T.4
Meliton, A.5
Leff, A.6
Birukova, A.A.7
-
30
-
-
0033565732
-
Tumor infiltration by adoptively transferred T cells is independent of immunologic specificity but requires down-regulation of L-selectin expression
-
J. Kjaergaard, S. Shu, Tumor infiltration by adoptively transferred T cells is independent of immunologic specificity but requires down-regulation of L-selectin expression. J. Immunol. 163, 751-759 (1999).
-
(1999)
J. Immunol.
, vol.163
, pp. 751-759
-
-
Kjaergaard, J.1
Shu, S.2
-
31
-
-
0038690157
-
Therapeutic efficacy of adoptive immunotherapy is predicated on in vivo antigen-specific proliferation of donor T cells
-
J. Kjaergaard, L. Peng, P. A. Cohen, S. Shu, Therapeutic efficacy of adoptive immunotherapy is predicated on in vivo antigen-specific proliferation of donor T cells. Clin. Immunol. 108, 8-20 (2003).
-
(2003)
Clin. Immunol.
, vol.108
, pp. 8-20
-
-
Kjaergaard, J.1
Peng, L.2
Cohen, P.A.3
Shu, S.4
-
32
-
-
77951683908
-
Effect of NKG2D ligand expression on host immune responses
-
M. Champsaur, L. L. Lanier, Effect of NKG2D ligand expression on host immune responses. Immunol. Rev. 235, 267-285 (2010).
-
(2010)
Immunol. Rev.
, vol.235
, pp. 267-285
-
-
Champsaur, M.1
Lanier, L.L.2
-
33
-
-
84875509728
-
Regulation of ligands for the NKG2D activating receptor
-
D. H. Raulet, S. Gasser, B. G. Gowen, W. Deng, H. Jung, Regulation of ligands for the NKG2D activating receptor. Annu. Rev. Immunol. 31, 413-441 (2013).
-
(2013)
Annu. Rev. Immunol.
, vol.31
, pp. 413-441
-
-
Raulet, D.H.1
Gasser, S.2
Gowen, B.G.3
Deng, W.4
Jung, H.5
-
34
-
-
51049108540
-
Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma
-
S. A. Quezada, K. S. Peggs, T. R. Simpson, Y. Shen, D. R. Littman, J. P. Allison, Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma. J. Exp. Med. 205, 2125-2138 (2008).
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2125-2138
-
-
Quezada, S.A.1
Peggs, K.S.2
Simpson, T.R.3
Shen, Y.4
Littman, D.R.5
Allison, J.P.6
-
35
-
-
62449170994
-
Tumor-induced suppression of CTL expansion and subjugation by gp96-Ig vaccination
-
T. H. Schreiber, V. V. Deyev, J. D. Rosenblatt, E. R. Podack, Tumor-induced suppression of CTL expansion and subjugation by gp96-Ig vaccination. Cancer Res. 69, 2026-2033 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 2026-2033
-
-
Schreiber, T.H.1
Deyev, V.V.2
Rosenblatt, J.D.3
Podack, E.R.4
-
36
-
-
58149147369
-
Hypoxia-adenosinergic immunosuppression: Tumor protection by T regulatory cells and cancerous tissue hypoxia
-
M. V. Sitkovsky, J. Kjaergaard, D. Lukashev, A. Ohta, Hypoxia-adenosinergic immunosuppression: Tumor protection by T regulatory cells and cancerous tissue hypoxia. Clin. Cancer Res. 14, 5947-5952 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 5947-5952
-
-
Sitkovsky, M.V.1
Kjaergaard, J.2
Lukashev, D.3
Ohta, A.4
-
37
-
-
53749094183
-
+ regulatory T cell function
-
+ regulatory T cell function. Science 322, 271-275 (2008).
-
(2008)
Science
, vol.322
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
Yamaguchi, T.4
Miyara, M.5
Fehervari, Z.6
Nomura, T.7
Sakaguchi, S.8
-
38
-
-
0035576267
-
Augmentation versus inhibition: Effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor
-
J. Kjaergaard, L. Peng, P. A. Cohen, J. A. Drazba, A. D. Weinberg, S. Shu, Augmentation versus inhibition: Effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor. J. Immunol. 167, 6669-6677 (2001).
-
(2001)
J. Immunol.
, vol.167
, pp. 6669-6677
-
-
Kjaergaard, J.1
Peng, L.2
Cohen, P.A.3
Drazba, J.A.4
Weinberg, A.D.5
Shu, S.6
-
39
-
-
0030803163
-
Memory of extracellular adenosine A#INF#2#/INF#A purinergic receptor-mediated signaling in murine T cells
-
M. Koshiba, H. Kojima, S. Huang, S. Apasov, M.V. Sitkovsky, Memory of extracellular adenosine A#INF#2#/INF#A purinergic receptor-mediated signaling in murine T cells. J. Biol. Chem. 272, 25881-25889 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25881-25889
-
-
Koshiba, M.1
Kojima, H.2
Huang, S.3
Apasov, S.4
Sitkovsky, M.V.5
-
40
-
-
0033954723
-
Chronic hypoxia enhances adenosine release in rat PC12 cells by altering adenosine metabolism and membrane transport
-
S. Kobayashi, H. Zimmermann, D. E. Millhorn, Chronic hypoxia enhances adenosine release in rat PC12 cells by altering adenosine metabolism and membrane transport. J. Neurochem. 74, 621-632 (2000).
-
(2000)
J. Neurochem.
, vol.74
, pp. 621-632
-
-
Kobayashi, S.1
Zimmermann, H.2
Millhorn, D.E.3
-
41
-
-
0030747295
-
Hypoxia-induced inhibition of adenosine-kinase potentiates cardiac adenosine release
-
U. K. Decking, G. Schlieper, K. Kroll, J. Schrader, Hypoxia-induced inhibition of adenosine-kinase potentiates cardiac adenosine release. Circ. Res. 81, 154-164 (1997).
-
(1997)
Circ. Res.
, vol.81
, pp. 154-164
-
-
Decking, U.K.1
Schlieper, G.2
Kroll, K.3
Schrader, J.4
-
42
-
-
85047685683
-
Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia
-
K. Synnestvedt, G. T. Furuta, K. M. Comerford, N. Louis, J. Karhausen, H. K. Eltzschig, K. R. Hansen, L. F. Thompson, S. P. Colgan, Ecto-5'-nucleotidase (CD73) regulation by hypoxia-inducible factor-1 mediates permeability changes in intestinal epithelia. J. Clin. Invest. 110, 993-1002 (2002).
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 993-1002
-
-
Synnestvedt, K.1
Furuta, G.T.2
Comerford, K.M.3
Louis, N.4
Karhausen, J.5
Eltzschig, H.K.6
Hansen, K.R.7
Thompson, L.F.8
Colgan, S.P.9
-
43
-
-
78149330949
-
HIF-1a regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
-
C. A. Corzo, T. Condamine, L. Lu, M. J. Cotter, J. I. Youn, P. Cheng, H. I. Cho, E. Celis, D. G. Quiceno, T. Padhya, T. V. McCaffrey, J. C McCaffrey, D. I. Gabrilovich, HIF-1a regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. J. Exp. Med. 207, 2439-2453 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2439-2453
-
-
Corzo, C.A.1
Condamine, T.2
Lu, L.3
Cotter, M.J.4
Youn, J.I.5
Cheng, P.6
Cho, H.I.7
Celis, E.8
Quiceno, D.G.9
Padhya, T.10
McCaffrey, T.V.11
McCaffrey, J.C.12
Gabrilovich, D.I.13
-
44
-
-
84907223092
-
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
-
O. R. Colegio, N.-Q. Chu, A. L Szabo, T. Chu, A. Marie Rhebergen, V. Jairam, N. Cyrus, C E. Brokowski, S. C. Eisenbarth, G. M. Phillips, G. W. Cline, A. J. Phillips, R. Medzhitov, Functional polarization of tumour-associated macrophages by tumour-derived lactic acid. Nature 513, 559-563 (2014).
-
(2014)
Nature
, vol.513
, pp. 559-563
-
-
Colegio, O.R.1
Chu, N.-Q.2
Szabo, A.L.3
Chu, T.4
Marie Rhebergen, A.5
Jairam, V.6
Cyrus, N.7
Brokowski, C.E.8
Eisenbarth, S.C.9
Phillips, G.M.10
Cline, G.W.11
Phillips, A.J.12
Medzhitov, R.13
-
45
-
-
84901046659
-
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
-
P. Chaturvedi, D. M. Gilkes, N. Takano, G. L. Semenza, Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment. Proc. Natl. Acad. Sci. U.S.A. 111, E2120-E2129 (2014).
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. E2120-E2129
-
-
Chaturvedi, P.1
Gilkes, D.M.2
Takano, N.3
Semenza, G.L.4
-
46
-
-
33748313243
-
Caveats in promising therapeutic targeting of the anti-inflammatory A2 adenosine receptors: The notes of caution
-
A. Ohta, M. Sitkovsky, Caveats in promising therapeutic targeting of the anti-inflammatory A2 adenosine receptors: The notes of caution. Nat. Rev. Drug Discov. 5 (2006).
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
-
-
Ohta, A.1
Sitkovsky, M.2
-
47
-
-
0034099007
-
Chronic hyper-capnia inhibits hypoxic pulmonary vascular remodeling
-
H. Ooi, E. Cadogan, M. Sweeney, K. Howell, R. G. O'Regan, P. McLoughlin, Chronic hyper-capnia inhibits hypoxic pulmonary vascular remodeling. Am. J. Physiol. Heart Circ. Physiol. 278, H331-H338 (2000).
-
(2000)
Am. J. Physiol. Heart Circ. Physiol.
, vol.278
, pp. H331-H338
-
-
Ooi, H.1
Cadogan, E.2
Sweeney, M.3
Howell, K.4
O'Regan, R.G.5
McLoughlin, P.6
-
48
-
-
37049008461
-
Hypercapnic acidosis modulates inflammation, lung mechanics, and edema in the isolated perfused lung
-
H. R. De Smet, A. D. Bersten, H. A. Barr, I. R. Doyle, Hypercapnic acidosis modulates inflammation, lung mechanics, and edema in the isolated perfused lung. J. Crit. Care 22, 305-313 (2007).
-
(2007)
J. Crit. Care
, vol.22
, pp. 305-313
-
-
De Smet, H.R.1
Bersten, A.D.2
Barr, H.A.3
Doyle, I.R.4
-
49
-
-
0034306979
-
Therapeutic efficacy of OX-40 receptor antibody depends on tumor immunogenicity and anatomic site of tumor growth
-
J. Kjaergaard, J. Tanaka, J. A. Kim, K. Rothchild, A. Weinberg, S. Shu, Therapeutic efficacy of OX-40 receptor antibody depends on tumor immunogenicity and anatomic site of tumor growth. Cancer Res. 60, 5514-5521 (2000).
-
(2000)
Cancer Res.
, vol.60
, pp. 5514-5521
-
-
Kjaergaard, J.1
Tanaka, J.2
Kim, J.A.3
Rothchild, K.4
Weinberg, A.5
Shu, S.6
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