메뉴 건너뛰기




Volumn 68, Issue 4, 2015, Pages 253-258

Antimicrobial activity of a quinuclidine-based FtsZ inhibitor and its synergistic potential with β-lactam antibiotics

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; CEFOXITIN; CEFTAZIDIME; FTSZ PROTEIN; HYDROLASE INHIBITOR; IMIPENEM; METICILLIN; OXACILLIN; QUINUCLIDINE 1; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BETA LACTAM; CYTOSKELETON PROTEIN; FTSZ PROTEIN, BACTERIA; QUINUCLIDINE DERIVATIVE;

EID: 84928951939     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2014.140     Document Type: Article
Times cited : (37)

References (27)
  • 1
    • 75949092121 scopus 로고    scopus 로고
    • Anti-virulence strategies to combat bacteria-mediated disease
    • Rasko, D. A., Sperandio, V. Anti-virulence strategies to combat bacteria-mediated disease. Nat. Rev. Drug Discov. 9, 117-128 (2010).
    • (2010) Nat. Rev. Drug Discov , vol.9 , pp. 117-128
    • Rasko, D.A.1    Sperandio, V.2
  • 2
    • 52249094198 scopus 로고    scopus 로고
    • Microbiology. Desperately seeking new antibiotics
    • Payne, D. J. Microbiology. Desperately seeking new antibiotics. Science 321, 1644-1645 (2008).
    • (2008) Science , vol.321 , pp. 1644-1645
    • Payne, D.J.1
  • 3
    • 69549111337 scopus 로고    scopus 로고
    • Antibiotics for emerging pathogens
    • Fischbach, M. A., Walsh, C. T. Antibiotics for emerging pathogens. Science 325, 1089-1093 (2009).
    • (2009) Science , vol.325 , pp. 1089-1093
    • Fischbach, M.A.1    Walsh, C.T.2
  • 4
    • 74049161613 scopus 로고    scopus 로고
    • Surface disinfection properties of the combination of an antimicrobial peptide, ranalexin, with an endopeptidase, lysostaphin, against methicillin-resistant Staphylococcus aureus (MRSA).
    • Desbois, A. P., Lang, S., Gemmell, C. G., Coote, P. J. Surface disinfection properties of the combination of an antimicrobial peptide, ranalexin, with an endopeptidase, lysostaphin, against methicillin-resistant Staphylococcus aureus (MRSA). J. Appl. Microbiol. 108, 723-730 (2010).
    • (2010) J. Appl. Microbiol , vol.108 , pp. 723-730
    • Desbois, A.P.1    Lang, S.2    Gemmell, C.G.3    Coote, P.J.4
  • 5
    • 74249108028 scopus 로고    scopus 로고
    • Three decades of beta-lactamase inhibitors
    • Drawz, S. M., Bonomo, R. A. Three decades of beta-lactamase inhibitors. Clin. Microbiol. Rev. 23, 160-201 (2010).
    • (2010) Clin. Microbiol. Rev , vol.23 , pp. 160-201
    • Drawz, S.M.1    Bonomo, R.A.2
  • 6
    • 0028872562 scopus 로고
    • FtsZ a prokaryotic homolog of tubulin
    • Erickson, H. P. FtsZ, a prokaryotic homolog of tubulin. Cell 80, 367-370 (1995).
    • (1995) Cell , vol.80 , pp. 367-370
    • Erickson, H.P.1
  • 7
    • 0026059127 scopus 로고
    • FtsZ ring structure associated with division in Escherichia coli
    • Bi, E., Lutkenhaus, J. FtsZ ring structure associated with division in Escherichia coli. Nature 354, 161-164 (1991).
    • (1991) Nature , vol.354 , pp. 161-164
    • Bi, E.1    Lutkenhaus, J.2
  • 8
    • 13444274140 scopus 로고    scopus 로고
    • Structural insights into FtsZ protofilament formation
    • Oliva, M. A., Cordell, S. C., Lowe, J. Structural insights into FtsZ protofilament formation. Nat. Struct. Mol. Biol. 11, 1243 (2004).
    • (2004) Nat. Struct. Mol. Biol , vol.11 , pp. 1243
    • Oliva, M.A.1    Cordell, S.C.2    Lowe, J.3
  • 9
    • 77955891916 scopus 로고    scopus 로고
    • FtsZ inhibition: A promising approach for antistaphylococcal therapy
    • Singh, P., Panda, D. FtsZ inhibition: a promising approach for antistaphylococcal therapy. Drug news perspect. 23, 295-304 (2010).
    • (2010) Drug News Perspect , vol.23 , pp. 295-304
    • Singh, P.1    Panda, D.2
  • 10
    • 68549092791 scopus 로고    scopus 로고
    • Targeting FtsZ for antibacterial therapy: A promising avenue
    • Kapoor, S., Panda, D. Targeting FtsZ for antibacterial therapy: a promising avenue. Expert Opin. Ther. Tar. 13, 1037-1051 (2009).
    • (2009) Expert Opin. Ther. Tar , vol.13 , pp. 1037-1051
    • Kapoor, S.1    Panda, D.2
  • 11
    • 42149131579 scopus 로고    scopus 로고
    • Cell-division inhibitors: New insights for future antibiotics
    • Lock, R. L., Harry, E. J. Cell-division inhibitors: New insights for future antibiotics. Nat. Rev. Drug Discov. 7, 324-338 (2008).
    • (2008) Nat. Rev. Drug Discov , vol.7 , pp. 324-338
    • Lock, R.L.1    Harry, E.J.2
  • 12
    • 79955120811 scopus 로고    scopus 로고
    • Therapeutic potential of FtsZ inhibition: A patent perspective
    • Awasthi, D., Kumar, K., Ojima, I. Therapeutic potential of FtsZ inhibition: a patent perspective. Expert Opin. Ther. Pat. 21, 657-679 (2011).
    • (2011) Expert Opin. Ther. Pat , vol.21 , pp. 657-679
    • Awasthi, D.1    Kumar, K.2    Ojima, I.3
  • 13
    • 84857549874 scopus 로고    scopus 로고
    • Targeting the assembly of bacterial cell division protein FtsZ with small molecules
    • Schaffner-Barbero, C., Martin-Fontecha, M., Chacon, P., Andreu, J. M. Targeting the assembly of bacterial cell division protein FtsZ with small molecules. ACS Chem. Biol. 7, 269-277 (2012).
    • (2012) ACS Chem. Biol , vol.7 , pp. 269-277
    • Schaffner-Barbero, C.1    Martin-Fontecha, M.2    Chacon, P.3    Andreu, J.M.4
  • 14
    • 84883241483 scopus 로고    scopus 로고
    • Identification of a new class of FtsZ inhibitors by structure-based design and in vitro screening
    • Chan, F. Y. et al. Identification of a new class of FtsZ inhibitors by structure-based design and in vitro screening. J. Chem. Inf. Model. 53, 2131-2140 (2013).
    • (2013) J. Chem. Inf. Model , vol.53 , pp. 2131-2140
    • Chan, F.Y.1
  • 15
    • 84908210522 scopus 로고    scopus 로고
    • Restoring methicillin-resistant Staphylococcus aureus susceptibility to beta-lactam antibiotics
    • Tan, C. M. et al. Restoring methicillin-resistant Staphylococcus aureus susceptibility to beta-lactam antibiotics. Sci. Transl. Med. 4, 126ra135 (2012).
    • (2012) Sci. Transl. Med , vol.4 , pp. 126ra135
    • Tan, C.M.1
  • 16
    • 84884668580 scopus 로고    scopus 로고
    • Synthetic inhibitors of bacterial cell division targeting the GTPbinding site of FtsZ
    • Ruiz-Avila, L. B. et al. Synthetic inhibitors of bacterial cell division targeting the GTPbinding site of FtsZ. ACS Chem. Biol. 8, 2072-2083 (2013).
    • (2013) ACS Chem. Biol , vol.8 , pp. 2072-2083
    • Ruiz-Avila, L.B.1
  • 17
    • 84901336638 scopus 로고    scopus 로고
    • Rational design of berberine-based FtsZ inhibitors with broad-spectrum antibacterial activity
    • Sun, N. et al. Rational design of berberine-based FtsZ inhibitors with broad-spectrum antibacterial activity. PLoS ONE 9, e97514 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e97514
    • Sun, N.1
  • 18
    • 0242606152 scopus 로고    scopus 로고
    • Dispersed mode of Staphylococcus aureus cell wall synthesis in the absence of the division machinery
    • Pinho, M. G., Errington, J. Dispersed mode of Staphylococcus aureus cell wall synthesis in the absence of the division machinery. Mol. Microbiol. 50, 871-881 (2003).
    • (2003) Mol. Microbiol , vol.50 , pp. 871-881
    • Pinho, M.G.1    Errington, J.2
  • 19
    • 0003457567 scopus 로고    scopus 로고
    • Performance Standards for Antimicrobial Susceptibility Testing
    • Clinical and Laboratory Standards Institute Wayne, PA, USA
    • Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing; Nineteenth Informational Supplement CLSI document M100-S19 CLSI: Wayne, PA, USA, (2009).
    • (2009) Nineteenth Informational Supplement CLSI Document M100-S19 CLSI
  • 20
    • 0004286502 scopus 로고    scopus 로고
    • 5th edn. Antimicrobial Combinations (eds Pillai S. K., Moellering R. C. J., Eliopoulos G. M.) (Lippincott Williams & Wilkins: Philadelphia, PA, USA
    • Lorian, V. in. Antibiotics in Laboratory Medicine 5th edn. Antimicrobial Combinations (eds Pillai S. K., Moellering R. C. J., Eliopoulos G. M.) 365-440 (Lippincott Williams & Wilkins: Philadelphia, PA, USA, 2005).
    • (2005) Antibiotics in Laboratory Medicine , pp. 365-440
    • Lorian, V.1
  • 21
    • 0038601510 scopus 로고    scopus 로고
    • Synergy antagonism, and what the chequerboard puts between them
    • Odds, F. C. Synergy, antagonism, and what the chequerboard puts between them. J. Antimicrob. Chemother. 52, 1 (2003).
    • (2003) J. Antimicrob. Chemother , vol.52 , pp. 1
    • Odds, F.C.1
  • 22
    • 0037423396 scopus 로고    scopus 로고
    • Glutamate-induced assembly of bacterial cell division protein FtsZ
    • Beuria, T. K. et al. Glutamate-induced assembly of bacterial cell division protein FtsZ. J. Biol. Chem. 278, 3735-3741 (2003).
    • (2003) J. Biol. Chem , vol.278 , pp. 3735-3741
    • Beuria, T.K.1
  • 23
    • 29244432515 scopus 로고    scopus 로고
    • Sanguinarine blocks cytokinesis in bacteria by inhibiting FtsZ assembly and bundling
    • Beuria, T. K., Santra, M. K., Panda, D. Sanguinarine blocks cytokinesis in bacteria by inhibiting FtsZ assembly and bundling. Biochemistry 44, 16584-16593 (2005).
    • (2005) Biochemistry , vol.44 , pp. 16584-16593
    • Beuria, T.K.1    Santra, M.K.2    Panda, D.3
  • 24
    • 0033823009 scopus 로고    scopus 로고
    • Themes and variations in prokaryotic cell division
    • Margolin, W. Themes and variations in prokaryotic cell division. Fems. Microbiol. Rev. 24, 531-548 (2000).
    • (2000) Fems. Microbiol. Rev , vol.24 , pp. 531-548
    • Margolin, W.1
  • 25
    • 52249120794 scopus 로고    scopus 로고
    • An inhibitor of FtsZ with potent and selective anti-staphylococcal activity
    • Haydon, D. J. et al. An inhibitor of FtsZ with potent and selective anti-staphylococcal activity. Science 321, 1673-1675 (2008).
    • (2008) Science , vol.321 , pp. 1673-1675
    • Haydon, D.J.1
  • 26
    • 84899678758 scopus 로고    scopus 로고
    • A trisubstituted benzimidazole cell division inhibitor with efficacy against Mycobacterium tuberculosis
    • Knudson, S. E. et al. A trisubstituted benzimidazole cell division inhibitor with efficacy against Mycobacterium tuberculosis. PLoS ONE 9, e93953 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e93953
    • Knudson, S.E.1
  • 27
    • 28844488672 scopus 로고    scopus 로고
    • Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assay
    • Stokes, N. R. et al. Novel inhibitors of bacterial cytokinesis identified by a cell-based antibiotic screening assay. J. Biol. Chem. 280, 39709-39715 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 39709-39715
    • Stokes, N.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.