The effect of ligand density on in vivo tumor targeting of nanographene oxide

Journal of Controlled Release

Volumn 209, Issue , 2015, Pages 219-228

  Lee, Jong Hyun ^a   Sahu, Abhishek ^a   Jang, Cheol ^a   Tae, Giyoong ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

Active targeting; Folate; Graphene oxide; Ligand density; Pluronic

Indexed keywords

COATINGS; GRAPHENE; LIGANDS; MAMMALS; MOBILE SECURITY;

ACTIVE TARGETING; FOLATE; GRAPHENE OXIDES; LIGAND DENSITY; PLURONICS;

TUMORS;

FOLATE RECEPTOR; GRAPHENE OXIDE; POLOXAMER; FOLATE TRANSPORTER; FOLIC ACID; GRAPHITE; LIGAND; NANOMATERIAL; OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG COATING; DRUG TARGETING; DRUG UPTAKE; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VIVO STUDY; KB CELL LINE; MOUSE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DENSITY; SURFACE PROPERTY; TUMOR ABLATION; TUMOR XENOGRAFT; 3T3 CELL LINE; ANIMAL; CHEMISTRY; DRUG EFFECTS; LOW LEVEL LASER THERAPY; MALE; MCF 7 CELL LINE; METABOLISM; NEOPLASMS; NUDE MOUSE; PATHOLOGY; PHOTOTHERAPY; TUMOR VOLUME;

ANIMALS; FOLIC ACID; FOLIC ACID TRANSPORTERS; GRAPHITE; HUMANS; KB CELLS; LASER THERAPY; LIGANDS; MALE; MCF-7 CELLS; MICE; MICE, NUDE; NANOSTRUCTURES; NEOPLASMS; NIH 3T3 CELLS; OXIDES; PHOTOTHERAPY; POLOXAMER; TUMOR BURDEN;

EID: 84928896005     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.04.035     Document Type: Article

References (37)

1. M. Ferrari Cancer nanotechnology: opportunities and challenges Nat. Rev. Cancer 5 2005 161 171
2. N. Bertrand, J. Wu, X. Xu, N. Kamaly, and O.C. Farokhzad Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology Adv. Drug Deliv. Rev. 66 2014 2 25
3. D. Peer, J.M. Karp, S. Hong, O.C. Farokhzad, R. Margalit, and R. Langer Nanocarriers as an emerging platform for cancer therapy Nat. Nanotechnol. 2 2007 751 760
4. H. Maeda, J. Wu, T. Sawa, Y. Matsumura, and K. Hori Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review J. Control. Release 65 2000 271 284
5. F. Danhier, O. Feron, and V. Préat To exploit the tumor microenvironment: passive and active tumor targeting of nanocarriers for anti-cancer drug delivery J. Control. Release 148 2010 135 461
6. R.K. Jain Barriers to drug-delivery in solid tumors Sci. Am. 271 1994 58 65
7. Y. Wang, Z. Li, J. Wang, J. Li, and Y. Lin Graphene and graphene oxide: biofunctionalization and applications in biotechnology Trends Biotechnol. 29 2011 205 212
8. S. Goenka, V. Sant, and S. Sant Graphene-based nanomaterials for drug delivery and tissue engineering J. Control. Release 173 2014 75 88
9. Z. Liu, J.T. Robinson, X. Sun, and H. Dai PEGylated nanographene oxide for delivery of water-insoluble cancer drugs J. Am. Chem. Soc. 130 2008 10876 10877
10. G. Shim, J.Y. Kim, J. Han, S.W. Chung, S. Lee, Y. Byun, and Y.K. Oh Reduced graphene oxide nanosheets coated with an anti-angiogenic anticancer low-molecular-weight heparin derivative for delivery of anticancer drugs J. Control. Release 189 2014 80 89
11. A.R. Maity, A. Chakraborty, A. Mondal, and N.R. Jana Carbohydrate coated, folate functionalized colloidal graphene as a nanocarrier for both hydrophobic and hydrophilic drugs Nanoscale 6 2014 2752 2758
12. Z. Sun, P. Huang, G. Tong, J. Lin, A. Jin, P. Rong, L. Zhu, L. Nie, G. Niu, F. Cao, and X. Chen VEGF-loaded graphene oxide as theranostics for multi-modality imaging-monitored targeting therapeutic angiogenesis of ischemic muscle Nanoscale 5 2013 6857 6866
13. B. Chen, M. Liu, L. Zhang, J. Huang, J. Yao, and Z. Zhang Polyethylenimine-functionalized graphene oxide as an efficient gene delivery vector J. Mater. Chem. 21 2014 7736 7741
14. A. Sahu, W.I. Choi, J.H. Lee, and G. Tae Graphene oxide mediated delivery of methylene blue for combined photodynamic and photothermal therapy Biomaterials 34 2013 6239 6248
15. J.T. Robinson, S.M. Tabakman, Y. Liang, H. Wang, H.S. Casalongue, D. Vinh, and H. Dai Ultrasmall reduced graphene oxide with high near-infrared absorbance for photothermal therapy J. Am. Chem. Soc. 133 2011 6825 6831
16. K. Yang, S. Zhang, G. Zhang, X. Sun, S.T. Lee, and Z. Liu Graphene in mice: ultrahigh in vivo tumor uptake and efficient photothermal therapy Nano Lett. 10 2010 3318 3323
17. W. Zhang, Z. Guo, D. Huang, Z. Liu, X. Guo, and H. Zhong Synergistic effect of chemo-photothermal therapy using PEGylated graphene oxide Biomaterials 32 2011 8555 8561
18. H. Kim, and W.J. Kim Photothermally controlled gene delivery by reduced graphene oxide-polyethylenimine nanocomposite Small 10 2014 117 126
19. J. Sudimack, and R.J. Lee Targeted drug delivery via the folate receptor Adv. Drug Deliv. Rev. 41 2000 147 162
20. J.A. Reddy, and P.S. Low Enhanced folate receptor mediated gene therapy using a novel pH-sensitive lipid formulation J. Control. Release 64 2000 27 37
21. X. Yang, Y. Wang, X. Huang, Y. Ma, Y. Huang, R. Yang, H. Duan, and Y. Chen Multi-functionalized graphene oxide based anticancer drug-carrier with dual-targeting function and pH-sensitivity J. Mater. Chem. 21 2011 3448 3454
22. X. Zhao, and P. Liu Biocompatible graphene oxide as a folate receptor-targeting drug delivery system for the controlled release of anti-cancer drugs RSC Adv. 4 2014 24232 24239
23. F. Gu, L. Zhang, B.A. Teply, N. Mann, A. Wang, A.F. Radovic-Moreno, R. Langer, and O.C. Farokhzad Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers Proc. Natl. Acad. Sci. 105 2008 2586 2591
24. Y. Zhong, F. Meng, C. Deng, and Z. Zhong Ligand-directed active tumor-targeting polymeric nanoparticles for cancer chemotherapy Biomacromolecules 15 2014 1955 1969
25. J.Y. Kim, W.I. Choi, Y.H. Kim, G. Tae, S.Y. Lee, K. Kim, and I.C. Kwon In vivo tumor targeting of pluronic-based nano-carriers J. Control. Release 147 2010 109 117
26. B.J. Hong, O.C. Compton, Z. An, I. Eryazici, and S.T. Nguyen Successful stabilization of graphene oxide in electrolyte solutions: enhancement of biofunctionalization and cellular uptake ACS Nano 6 2012 63 73
27. W. Miao, G. Shim, S. Lee, and Y.K. Oh Structure-dependent photothermal anticancer effects of carbon-based photoresponsive nanomaterials Biomaterials 35 2014 4058 4065
28. S. Hong, P.R. Leroueil, I.J. Majoros, B.G. Orr, J.R. Baker Jr., and M.M. Banaszak Holl The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform Chem. Biol. 14 2007 107 115
29. Z. Cheng, A.A. Zaki, J.Z. Hui, V.R. Muzykantov, and A. Tsourkas Multifunctional nanoparticles: cost versus benefit of adding targeting and imaging capabilities Science 338 2012 903 910
30. M. Shahin, R. Soudy, H.M. Aliabadi, N. Kneteman, K. Kaur, and A. Lavasanifar Engineered breast tumor targeting peptide ligand modified liposomal doxorubicin and the effect of peptide density on anticancer activity Biomaterials 34 2013 4089 4097
31. Z. Poon, S. Chen, A.C. Engler, H. Lee, E. Atas, G. Maltzahn, S.N. Bhatia, and P.T. Hammond Ligand-clustered "patchy" nanoparticles for modulated cellular uptake and in vivo tumor targeting Angew. Chem. Int. Ed. 49 2010 7266 7270
32. E. Moradi, D. Vllasaliu, M. Garnett, F. Falcone, and S. Stolnik Ligand density and clustering effects on endocytosis of folate modified nanoparticles RSC Adv. 2 2012 3025 3033
33. C.P. Leamon, S.R. Cooper, and G.E. Hardee Folate-liposome-mediated antisense oligodeoxynucleotide targeting to cancer cells: evaluation in vitro and in vivo Bioconjug. Chem. 14 2003 738 747
34. D.R. Elias, A. Poloukhtine, V. Popik, and A. Tsourkas Effect of ligand density, receptor density, and nanoparticle size on cell targeting Nanomedicine 9 2013 194 201
35. J. Zhao, Y. Mi, Y. Liu, and S.S. Feng Quantitative control of targeting effect of anticancer drugs formulated by ligand-conjugated nanoparticles of biodegradable copolymer blend Biomaterials 33 2012 1948 1958
36. Y. Liu, K. Li, B. Liu, and S.S. Feng A strategy for precision engineering of nanoparticles of biodegradable copolymers for quantitative control of targeted drug delivery Biomaterials 31 2010 9145 9155
37. Z. Tang, D. Li, H. Sun, X. Guo, Y. Chen, and S. Zhou Quantitative control of active targeting of nanocarriers to tumor cells through optimization of folate ligand density Biomaterials 35 2014 8015 8027